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| 1 | β-Cyclodextrin promoted oxidation of aldehydes to carboxylic acids in water显示文摘A facile,efficient and substrate-selective oxidation of aldehydes to carboxylic acids with NaClO catalyzed byβ-cyclodextrin in water has been developed.A series of aldehydes which could form inclusion complex withβ-cyclodextrin(β-CD)were oxidized selectively with excellent yields. | Dong Po Shi Hong Bing Ji | 2009 | Chinese Chemical Letters2009，20，2： | 7 |
| 2 | Chromosome-scale genome assembly of sweet cherry(Prunus avium L.)cv.Tieton obtained using long-read and Hi-C sequencing显示文摘Sweet cherry(Prunus avium)is an economically significant fruit species in the genus Prunus.However,in contrast to other important fruit trees in this genus,only one draft genome assembly is available for sweet cherry,which was assembled using only Illumina short-read sequences.The incompleteness and low quality of the current sweet cherry draft genome limit its use in genetic and genomic studies.A high-quality chromosome-scale sweet cherry reference genome assembly is therefore needed.A total of 65.05 Gb of Oxford Nanopore long reads and 46.24 Gb of Illumina short reads were generated,representing~190x and 136x coverage,respectively,of the sweet cherry genome.The final de novo assembly resulted in a phased haplotype assembly of 344.29 Mb with a contig N50 of 3.25 Mb.Hi-C scaffolding of the genome resulted in eight pseudochromosomes containing 99.59%of the bases in the assembled genome.Genome annotation revealed that more than half of the genome(59.40%)was composed of repetitive sequences,and 40,338 protein-coding genes were predicted,75.40%of which were functionally annotated.With the chromosomescale assembly,we revealed that gene duplication events contributed to the expansion of gene families for salicylic acid/jasmonic acid carboxyl methyltransferase and ankyrin repeat-containing proteins in the genome of sweet cherry.Four auxin-responsive genes(two GH3s and two SAURs)were induced in the late stage of fruit development,indicating that auxin is crucial for the sweet cherry ripening process.In addition,772 resistance genes were identified and functionally predicted in the sweet cherry genome.The high-quality genome assembly of sweet cherry obtained in this study will provide valuable genomic resources for sweet cherry improvement and molecular breeding. | Jiawei Wang Weizhen Liu Dongzi Zhu Po Hong Shizhong Zhang Shijun Xiao Yue Tan Xin Chen Li Xu Xiaojuan Zong Lisi Zhang Hairong Wei Xiaohui Yuan Qingzhong Liu | 2020 | Horticulture Research2020，7，1： | 4 |
| 3 | Loss of heterozygosity of Kras2 gene on 12p12-13 in Chinese colon carcinoma patients显示文摘瞄准:在中国冒号癌病人在 12p12-13 上学习杂合现象(LOH ) 的损失。方法:DNA 分别地从癌症组织,邻近的组织的 10 个标本和正常组织的 10 个标本的 10 个标本被提取。Kras2 基因的 LOH 被聚合酶链反应(PCR ) 和使中毒的 polyacrylamide 胶化电气泳动在 12p-12-13 上用 11 个微卫星标记分析。结果:Kras 基因的 LOH 在 30% 至少在 12p-12-13 的一个标记上被检测(3/10 ) 邻近的织物标本。LOH 的高频率在 28.57% 在 D12S1034 上被识别(2/7 ) 邻近的织物标本。LOH 至少在一个上被检测癌织物标本的在 60% 的 12p12-13 (6/10 ) 的标记,最经常的 LOH 在 42.86% 在 D12S1034 和 D12S1591 上被发现(3/7 ) 癌织物标本。LOH 在 30% 被检测(3/10 ) 癌组织标本,(3/10 )30% 在 1% 邻近的组织标本,并且不发信号(1/0 ) 癌组织标本。LOH 的出现没与性别,年龄,肿瘤尺寸和淋巴节点转移相关。结论:Genomic 不稳定性可以在冒号癌的发展和前进发生在 Kras2 基因的 12p-12-13 上。Kras2 基因的高 LOH 可以直接影响野类型 Kras2 基因的抄写和翻译。 | Jun wan Hong Li Yuan Li Mei-Ling Zhu Po Zhao | 2006 | World Journal of Gastroenterology2006，12，7： | 3 |
| 4 | Growth inhibitory effect of wild-type Kras2 gene on a colonic adenocarcinoma cell line显示文摘AIM: To observe the growth inhibitory effect of wild-type Kras2 gene on a colonic adenocarcinoma cell line Caco-2. METHODS: Recombinant plasmid pCI-neo-Kras2 with wild type Kras2 open reading frame was constructed. The Caco-2 cells were transfected with either pCI-neo or pCI-neo-Kras2 using Lipofectamine 2000. The expression of wild type Kras 2 was examined by Northern blot analysis. And the expression of wild type Kras2 protein was examined by Western blot analysis. The effects of wild-type Kras2 on cell proliferation were analyzed by monotetrazolium (MTT) assay, meanwhile analyses of cell cycle and spontaneous apoptosis rate were carried out by flow cytometry (FCM). RESULTS: The plasmid of pCI-neo-Kras 2 was successfully established. The growth rate of cells transfected with pCI-neo-Kras2 was significantly lower than the control cells transfected with the empty pCI-neo vector (P < 0.05). Cell cycle analysis revealed arrest of the pCI-neo-Kras2 transfected cells in G0/G1 phases, decreased DNA synthesis and decreased fractions of cells in S phase. The proliferative index of cells transfected with pCI-neo-Kras2 was decreased compared with the control cells (49.78% vs 64.21%),while the apoptotic rate of Caco-2 cells with stable Kras 2 expression increased (0.30% vs 0.02%). CONCLUSION: The wild-type Kras2 gene effectively inhibits the growth of the colonic adenocarcinoma cell line Caco-2. | Hong Li Hou-Fa Cao Jun Wan Yuan Li Mei-Ling Zhu Po Zhao | 2007 | World Journal of Gastroenterology2007，13，6： | 3 |
| 5 | Thermal effects in kilowatt fiber lasers显示文摘 | WANG Y XU Chang-Qing PO Hong | 2004 | IEEE Photonics Technology Letters2004，16，1： | 1 |
| 6 | Analysis of Raman and thermal effects in kilowatt fiber lasers显示文摘 | Yong Wang Chang-Qing Xu Hong Po | 2004 | Optics Communications2004，242，： | 1 |
| 7 | Thermal effects in kilowatt fiber lasers显示文摘 | Yong Wang Chang-Qing Xu Hong Po | 2004 | IEEE Photonics Technology Letters2004，16，： | 1 |
| 8 | High incidence of and risk factors for metachronous bilateral upper tract urothelial carcinoma in Taiwan显示文摘 | PO‐CHIENHUANG CHAO‐YUANHUANG SHI‐WEIHUANG MING‐KUENLAI HONG‐JENGYU JUNCHEN YEONG‐SHIAUPU | 2006 | International Journal of Urology2006，，7： | 1 |
| 9 | Thermal effects in kilowatt fiber lasers显示文摘 | Wang Yong Xu Changqing Po Hong | 2004 | IEEE Photonics Technology Letters2004，16，1： | 1 |
| 10 | Atrial Fibrillation Begets Atrial Fibrillation: Autonomic Mechanism for Atrial Electrical Remodeling Induced by Short-Term Rapid Atrial Pacing显示文摘 | Zhibing Lu Benjamin J. Scherlag Jiaxiong Lin Guodong Niu Kar-Ming Fung Lichao Zhao Muhammad Ghias Warren M. Jackman Ralph Lazzara Hong Jiang Sunny S. Po | 2008 | Circulation: Arrhythmia and Electrophysiology2008，，： | 1 |
| 11 | Analysis of Raman and thermal effects in kilowatt fiber lasers显示文摘 | Wang Yong Xu Changqing Po Hong | 2004 | Opt Commun2004，242，9： | 1 |
| 12 | Surgical resection versus transarterial chemoembolization for BCLC stage C hepatocellular carcinoma显示文摘 | Po‐Hong Liu Cheng‐Yuan Hsia Yun‐Hsuan Lee Chia‐Yang Hsu Yi‐Hsiang Huang Chien‐Wei Su Rheun‐Chuan Lee Han‐Chieh Lin Teh‐Ia Huo | 2015 | J. Surg. Oncol2015，，4： | 1 |
| 13 | Synthesis and characteristics of aqueous reactive urethane oligomer containing sulfoisophthalate sodium salt 显示文摘 | YEN MENG - SHUNG HUANG CHING - NAN HONG PO - DA | 2007 | Journal of Applied Polymer Science2007，106，5： | 1 |
| 14 | Discussion of aqueous urethane acrylate oligomers with sulfoisophthalate on the antistatic hydrophilic finishing of different fabrics显示文摘 | YEN MENG - SHUNG HUANG CHING - NAN HONG PO - DA | 2008 | Polymer Composites2008，29，1： | 1 |
| 15 | High- efficiency inverted polymer solar cells with solution-pro-cessed metal oxides 显示文摘 | Lin Yu Hong Yang Po Ching Huang Jing Shun | 2011 | Solar Energy Materials & Solar Ceils2011，95，： | 1 |
| 16 | Chemical properties and antioxidant activity of exopolysaccharides from mycelial culture of Cordyceps sinensisfungus Cs - HK1 显示文摘 | Po Hong Leung Shuna Zhao Kwok Ping Ho | 2009 | Food Chemistry2009，114，4： | 1 |
| 17 | Inhibitory effects of ethyl acetate extract of Cordyceps sinensis mycelium on various cancer cells in culture and B16 melanoma in C57BL/6 mice显示文摘 | Jian Yong Wu Qiao Xia Zhang Po Hong Leung | 2005 | Phytomedicine2005，，1： | 1 |
| 18 | Inhibitory effects of ethyl acetate extract of Cordyeeps sinensJs myeelium on various cancer cells in euhure and B16 melanoma in C57BL6 mice 显示文摘 | Jian Yong Wu Qiao Xia Zhang Po Hong Leung | 2007 | Phytomedieine2007，14，： | 1 |
| 19 | Quantification of hepatic steatosis: A comparison of the accuracy among multiple magnetic resonance techniques显示文摘 | Chih‐Horng Wu Ming‐Chih Ho Yung‐Ming Jeng Chao‐Yu Hsu Po‐Chin Liang Rey‐Heng Hu Hong‐Shiee Lai Tiffany Ting‐Fang Shih | 2014 | J Gastroenterol Hepatol2014，，4： | 1 |
| 20 | Large-scale economic dispatch by genetic algorithm显示文摘 | Po hung Chen Hong Chan Chang | 1995 | IEEE Transactions on Power Systems1995，10，4： | 1 |
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