|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Human thrombin for the treatment of gastric and ectopic varices显示文摘AIM:To evaluate the efficacy of human thrombin in the treatment of bleeding gastric and ectopic varices.METHODS:Retrospective observational study in a Tertiary Referral Centre.Between January 1999-October 2005,we identified 37 patients who were endoscopically treated with human thrombin injection therapy for bleeding gastric and ectopic varices.Patient details including age,gender and aetiology of liver disease/segmental portal hypertension were documented.The thrombin was obtained from the Scottish National Blood Transfusion Service and prepared to give a solution of 250 IU/mL which was injected via a standard injection needle.All patient case notes were reviewed and the total dose of thrombin given along with the number of endoscopy sessions was recorded.Initial haemostasis rates,rebleeding rates and mortality were catalogued along with the incidence of any immediate complications which could be attributable to the thrombin therapy.The duration of follow up was also listed.The study was conducted according to the United Kingdom research ethics guidelines.RESULTS:Thirty-seven patients were included.33 patients(89%) had thrombin(250 U/mL) for gastric varices,2(5.4%) for duodenal varices,1 for rectal varices and 1 for gastric and rectal varices.(1) Gastric varices,an average of 15.2 mL of thrombin was used per patient.Re-bleeding occurred in 4 patients(10.8%),managed in 2 by a transjugular intrahepatic portosystemic shunt(TIPSS)(one unsuccessfully who died) and in other 2 by a distal splenorenal shunt;(2) Duodenal varices(or type 2 isolated gastric varices),an average of 12.5 mL was used per patient over 2-3 endoscopy sessions.Re-bleeding occurred in one patient,which was treated by TIPSS;and(3) Rectal varices,an average of 18.3 mL was used per patient over 3 endoscopy sessions.No re-bleeding occurred in this group.CONCLUSION:Human thrombin is a safe,easy to use and effective therapeutic option to control haemorrhage from gastric and ectopic varices. | Norma C McAvoy John N Plevris Peter C Hayes | 2012 | World Journal of Gastroenterology2012，18，41： | 11 |
| 2 | 当在小肠的囊内视镜检查法计算路易斯分数时,蓝模式不在白光上提供任何利益显示文摘 AIM: To check the usefulness of blue mode (BM) review in lewis score (LS) calculation, by comparing it with respective LS results obtained by white light (WL) small-bowel capsule endoscopy (SBCE) review and mucosal inflammation as reflected by faecal calprotectin (FC) levels, considered as ’gold standard’ for this study. METHODS: Computational analysis of our SBCE database to identify patients who underwent SBCE with PillCam? and had FC measured within a 30-day period from their test. Only patients with prior colonoscopy were included, to exclude any colon pathology-associated FC rise. Each small bowel tertile was reviewed (viewing speed 8 fps) with WL and BM, in a back-to-back mode, by a single experienced reviewer. LS were calculated after each WL and BM reviews. Pearson rank correlation (rho, r) statistic was applied.RESULTS: Twenty-seven (n = 27, 20F/7M) patients were included. Thirteen (n = 13) had SBCE with PillCam?SB1, and the remainder (n = 14) with PillCam? SB2. The median level of FC in this cohort was 125 μg/g. LS (calculated in WL SBCE review) correlation with FC levels was r = 0.490 (P = 0.01), while for BM review and LS correlation with FC was r = 0.472 (P = 0.013). | Anastasios Koulaouzidis Sarah Douglas John N Plevris | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，2： | 3 |
| 3 | Gastrointestinal and liver disease in patients with schizophrenia:A narrative review显示文摘Schizophrenia is a severe mental illness which can have a devastating impact onan individual’s quality of life. Comorbidities are high amongst patients and lifeexpectancy is approximately 15 years less than the general population. Despite thewell-known increased mortality, little is known about the impact of gastrointestinaland liver disease on patients with schizophrenia. We aimed to reviewthe literature and to make recommendations regarding future care. Literaturesearches were performed on PubMed to identify studies related to gastrointestinaland liver disease in patients with schizophrenia. High rates of chronic liverdisease were reported, with Non-Alcoholic Fatty Liver Disease being of particularconcern;antipsychotics and metabolic syndrome were contributing factors. Ratesof acute liver failure were low but have been associated with antipsychotic useand paracetamol overdose. Coeliac disease has historically been linked to schizophrenia;however, recent research suggests that a causal link is yet to be proven.Evidence is emerging regarding the relationships between schizophrenia andpeptic ulcer disease, inflammatory bowel disease and irritable bowel syndrome;clinical vigilance regarding these conditions should be high. Patients with schizophreniapoorly engage with bowel cancer screening programmes, leading to latediagnosis and increased mortality. Clozapine induced constipation is a significantissue for many patients and requires close monitoring. There is a significantburden of gastrointestinal and liver disease amongst patients with schizophrenia.Better levels of support from all members of the medical team are essential toensure that appropriate, timely care is provided. | Rebecca K Grant William M Brindle Mhairi C Donnelly Pauline M McConville Thomas G Stroud Lorenzo Bandieri John N Plevris | 2022 | World Journal of Gastroenterology2022，28，38： | 2 |
| 4 | Primary graft dysfunction after liver transplantation: From pathogenesis to prevention显示文摘 | Khalid I Bzeizi Rajiv Jalan John N Plevris Peter C Hayes | 2003 | Liver Transpl2003，，2： | 2 |
| 5 | Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion显示文摘 | Philip N Newsome Ingolfur Johannessen Shelagh Boyle Evangelos Dalakas Karen A Mcaulay Kay Samuel Frances Rae Lesley Forrester Marc L Turner Peter C Hayes David J Harrison Wendy A Bickmore John N Plevris | 2003 | Gastroenterology2003，，7： | 2 |
| 6 | Update of endoscopy in liver disease:More than just treating varices显示文摘The management of complications in liver disease is often complex and challenging.Endoscopy has undergone a period of rapid expansion with numerous novel and specialized endoscopic modalities that are of increasing value in the investigation and management of the patient with liver disease.In this review,relevant literature search and expert opinions have been used to provide a brief overview and update of the current endoscopic management of patients with liver disease and portal hypertension.The main areas covered are safety of endoscopy in patients with liver disease,the use of standard endoscopy for the treatment of varices and the role of new endoscopic modalities such as endoscopic ultrasound,esophageal capsule,argon plasma coagulation,spyglass and endomicroscopy in the investigation and treatment of liver-related gastrointestinal and biliary pathology.It is clear that the role of the endoscopy in liver disease is well beyond that of just treating varices.As the technology in endoscopy expands,so does the role of the endoscopist in liver disease. | Christoforos Krystallis Gail S Masterton Peter C Hayes John N Plevris | 2012 | World Journal of Gastroenterology2012，18，5： | 2 |
| 7 | Review article : the management of acute liver failure 显示文摘 | Plevris J N Schina M Hayes P C | 1998 | Aliment Pharmacol Ther1998，12，5： | 1 |
| 8 | FRP-reinforced wood as structural material显示文摘 | Plevris N Triantafillou T C | 1992 | Journal of Materials in Civil Engineering-ASCE1992，4，3： | 1 |
| 9 | Prestressed FRP Sheetsas External Reinforcement of Wood members 显示文摘 | Triantafillou T C Plevris N and Deskovic N | 1992 | Journal ofStructural Engineering ASCE1992，118，5： | 1 |
| 10 | Creep Behavior of FRP-Reinforced WoodMembers显示文摘 | Plevris*N Triantafillou T C | 1995 | Journal of Structural Engineering ASCE1995，121，： | 1 |
| 11 | FRP-reinforced wood as structural material显示文摘 | PLEVRIS N TRIANTAFILLOU T C | | 0，，03： | 1 |
| 12 | A Lagrange multiplier solution for pounding of buildings during earthquakes 显示文摘 | PAPADRAKIS M MOUZAKIS H PLEVRIS N | 1991 | Earthquake Engineering and Structural Dy- namics1991，20，： | 1 |
| 13 | Creep behavior of FRP-reinforced wood members显示文摘 | PLEVRIS N TRIANTAFILLOU T C | | 0，，02： | 1 |
| 14 | Creep behavior of FRP-reinforced wood members closure显示文摘 | PLEVRIS N TRIANTAFILLOU C | | 0，，08： | 1 |
| 15 | FRP-reinforced wood as structural material 显示文摘 | Plevris N Triantafillou T | 1992 | Journal of Materials in Civil Engineering1992，4，3： | 1 |
| 16 | Creep behavior of FRP-reinforced wood members 显示文摘 | Plevris N Triantafillou T | 1995 | Journal of Structural Engineering1995，121，2： | 1 |
| 17 | Creep behavior of FRP-reinforced wood members显示文摘 | Plevris N Triantafillou T C | 1995 | Journal of Structural Engineering1995，121，2： | 1 |
| 18 | FRP-reinforced Wood as Structural Material 显示文摘 | Plevris N Triantafillou T | 1992 | Journal of Materials in Civil Engineering1992，3，4： | 1 |
| 19 | Strengthening of R/C Beams with Epoxy-bonded Fiber Composite Materials显示文摘 | T C Triantafillou and N Plevris | 1992 | Materials and Structures1992，25，4： | 1 |
| 20 | FRP-Reinforced Wood As a Structural Material显示文摘 | Plevris N Triantafillou T C | 1992 | Journal of Material in Civil Engineering1992，4，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员