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| 1 | An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China显示文摘 | Pixi Yan Youshu Zhao Xu Zhang Dawei Xu Xiaoguang Dai Qiaoyang Teng Liping Yan Jiewen Zhou Xiwen Ji Shumei Zhang Guangqing Liu Yanjun Zhou Yoshihiro Kawaoka Guangzhi Tong Zejun Li | 2011 | Virology2011，，1： | 5 |
| 2 | Mouse knockout models reveal largely dispensable but context-dependent functions of IncRNAs during development显示文摘 | Xue Han Sai Luo Guangdun Peng Yuyang Lu Guizhong Cui Lichao Liu Pixi Yan Yafei Yin Wei Liu Ran Wang Jiejie Zhang Shanshan Ai Zai Chang Jie Na Aibin He Naihe Jing Xiaohua Shen | 2018 | Journal of Molecular Cell Biology2018，10，2： | 3 |
| 3 | LncRNA Platr22 promotes super-enhancer activity and stem cell pluripotency显示文摘Super-enhancers(SEs)comprise large clusters of enhancers,which are co-occupied by multiple lineage-specific and master tran-scription factors,and play pivotal roles in regulating gene expression and cell fate determination.However,it is still largely un-known whether and how SEs are regulated by the noncoding portion of the genome.Here,through genome-wide analysis,wefound that tpng noncoding RNA(IncRNA)genes preferentially lie next to SEs.In mouse embryonic stem cells(mESCs),depletionof$E-associated IlncRNA transcripts dysregulated the activity of their nearby SEs.Specifically,we revealed a critical regulatoryrole of the IncRNA gene Platr22 in modulating the activity of a nearby SE and the expression of the nearby pluripotency regulatorZFP281.Through these regulatory events,Platr22 contributes to pluripotency maintenance and proper differentiation of mESCs.Mechanistically,Platr22 transcripts coat chromatin near the SE region and interact with DDX5 and hnRNP-L.DDX5 further recruitsp300 and other factors related to active transcription.We propose that these factors assemble into a transcription hub,thus pro-moting an open and active epigenetic chromatin state.0ur study highlights an unanticipated role for a class of lncRNAs in epige-netically controlling the activity and vulnerability to perturbation of nearby SEs for cell fate determination. | Pixi Yan Yuyang Lu Jing Niu Juntao Gao Michael Q.Zhang Yafei Yin Xiaohua Shen | 2021 | Journal of Molecular Cell Biology2021，13，4： | 2 |
| 4 | An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China显示文摘 | Pixi Yan Youshu Zhao Xu Zhang | 2011 | Virology2011，417，： | 1 |
| 5 | Establishing a TaqMan-Based Real-Time PCR Assay for the Rapid Detection and Quantification of the Newly Emerged Duck Tembusu Virus显示文摘 | Liping Yan Pixi Yan Jiewen Zhou | 2011 | Virology Journal2011，8，： | 1 |
| 6 | An in-fectious disease of ducks caused by a newly e-merged Tembusu virus strain in mainland China显示文摘 | Yan pixi Zhao youshu Zhang xu | | 0，，： | 1 |
| 7 | Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome显示文摘Organization of the genome into euchromatin and heterochromatin appears to be evolutionarily conserved and relatively stable during lineage differentiation.In an effort to unravel the basic principle underlying genome folding,here we focus on the genome itself and report a fundamental role for L1(LINE1 or LINE-1)and B1/Alu retrotransposons,the most abundant subclasses of repetitive sequences,in chromatin compartmentalization.We find that homotypic clustering of L1 and B1/Alu demarcates the genome into grossly exclusive domains,and characterizes and predicts Hi-C compartments.Spatial segregation of L1-rich sequences in the nuclear and nucleolar peripheries and B1/Alu-rich sequences in the nuclear interior is conserved in mouse and human cells and occurs dynamically during the cell cycle.In addition,de novo establishment of L1 and B1 nuclear segregation is coincident with the formation of higher-order chromatin structures during early embryogenesis and appears to be critically regulated by L1 and B1 transcripts.Importantly,depletion of L1 transcripts in embryonic stem cells drastically weakens homotypic repeat contacts and compartmental strength,and disrupts the nuclear segregation of L1-or B1-rich chromosomal sequences at genome-wide and individual sites.Mechanistically,nuclear co-localization and liquid droplet formation of L1 repeat DNA and RNA with heterochromatin protein HP1αsuggest a phase-separation mechanism by which L1 promotes heterochromatin compartmentalization.Taken together,we propose a genetically encoded model in which L1 and B1/Alu repeats blueprint chromatin macrostructure.Our model explains the robustness of genome folding into a common conserved core,on which dynamic gene regulation is overlaid across cells. | J.Yuyang Lu Lei Chang Tong Li Ting Wang Yafei Yin Ge Zhan Xue Han Ke Zhang Yibing Tao Michelle Percharde Liang Wang Qi Peng Pixi Yan Hui Zhang Xianju Bi Wen Shao Yantao Hong Zhongyang Wu Runze Ma Peizhe Wang Wenzhi Li Jing Zhang Zai Chang Yingping Hou Bing Zhu Miguel Ramalho-Santos Pilong Li Wei Xie Jie Na Yujie Sun Xiaohua Shen | 2021 | Cell Research2021，31，6： | 1 |
| 8 | Establishing a TaqMan-based real-time PCR assay for the rapid detection and quantification of the newly emerged duck Tembusu virus显示文摘 | Yan Liping Yan Pixi Zhou Jiewen | 2011 | Virol J2011，8，1： | 1 |
| 9 | Comparison of real-time reverse transcription loop-mediated isothermal amplification and real-time reverse transcription polymerase chain reaction for duck Tembusu virus显示文摘 | Liping Yan Shan Peng Pixi Yan Jiewen Zhou Qiaoyang Teng Guoxin Li Xuesong Li Zejun Li | 2012 | Journal of Virological Methods (-)2012，，1： | 1 |
| 10 | Changes irl'anthocyanin and phenolic content of grapevine leaf and fruit tissue treated with sucrose ,nitrate and abscisic acid 显示文摘 | Pixie A Mullins MG | 1976 | plant physical1976，58，： | 1 |
| 11 | An infectious disease of ducks caused by a newly emerged tembusu virus strain in mainland China 显示文摘 | Yan Pixi Zhao Youshu Zhang Xu | 2011 | Virology2011，417，1： | 1 |
| 12 | An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China显示文摘 | Pixi Yan Youshu Zhao Xu Zhang et al | 2011 | Virology2011，417，1： | 1 |
| 13 | Synthesis of thermoelectric materials by mechanical alloying in planetary ball mills显示文摘 | Schilz J Riifel M Pixies K | 1999 | Powder Technology1999，105，13： | 1 |
| 14 | Writing In Cyberspace显示文摘 | Pixie | 1997 | Computer-Mediated Communication Magazine1997，38，6： | 1 |
| 15 | 何需靓彩 高亮模式轻松拥有显示文摘元旦给正在上高中的小妹配了台电脑,不料没多久她就抱怨打游戏时屏幕太暗,调节OSD太麻烦,严重影响游戏“成绩”,时常央求我给她买块带有靓彩模式的ASUS显卡。但笔者苦于兜里没有银子,只好在小妹的埋怨声中一天天度过。笔者也曾向朋友求救过,得到的答案是可以通过修改显卡BIOS开启靓彩功能,但由于担心刷坏显卡而迟迟没有动手操作。直到遇到它,本文的主角——DarkAdapted,它帮我轻松解决了这个难题。下面,就让我们一起来看看如何使用这个小软件吧。 | pixy | 2006 | 计算机应用文摘2006，，7： | 0 |
| 16 | 轻松打造毒霸应急盘显示文摘如今的互联网,各种各样的病毒异常猖獗,稍不留意就会“中彩”。而且多数情况下,这些顽固病毒在WIndows界面中很难清除干净,只有在DOS下才能被彻底查杀。所以,制作一套DOS应急盘备用十分必要,本文将以《金山毒霸2005》为例介绍一下具体的制作步骤及使用方法。 | pixy | 2005 | 计算机应用文摘2005，，22： | 0 |
| 17 | 一分钟远离垃圾邮件显示文摘各种各样的垃圾邮件如同随处可见的小广告,成为网络的一种公害。网民朋友们每天都会多次和它们打“交道”。大量的病毒或木马又通过电子邮件进行传播,所以防范垃圾邮件对我们来说至关重要。那么,如何才能有效地阻止垃圾邮件,让它们远离我们的网络生活呢? | pixy | 2005 | 计算机应用文摘2005，21，19： | 0 |
| 18 | 反义长链非编码RNA调控基因表达和多能干细胞分化显示文摘高等真核生物基因组的广泛转录产生了大量的长链非编码RNA(lncRNA),它们不具有编码蛋白的功能。目前人们对它们的了解还非常有限,lncRNA被认为是生物学中的暗物质。LncRNA的功能分类及预测,是非编码RNA领域一直追寻和探索的重要问题,它对于认识非编码RNA生物学功能和存在的意义具有重要作用。 | Sai Luo J.Yuyang Lu Lichao Liu Yafei Yin Chunyan Chen Xue Han Bohou Wu Ronggang Xu Wei Liu Pixi Yan Wen Shao Zhi Lu Haitao Li Jie Na Fuchou Tang Jianlong Wang Yong E.Zhang 沈晓骅 | 2017 | 科学新闻2017，19，4： | 0 |
| 19 | 摄影师的自觉——Blood Pixy显示文摘作为一个摄影师/艺术家到底要怎么定义自己?我是不是一个摄影师/艺术家呢?对于这一点每个人都会有自己的衡量标准.艺术/摄影给我们一个方式去探索。在不断的实验中我们也许可以更加认识自己.同时也是一个自我发掘的过程。Blood Pixy说:“摄影师/艺术家之于我是很遥远的.也许摄影已经成为我自我疗伤的过程。”我们的内心总有一些或不为人知或想要表述的东西. | 王溪 Blood Pixy(图) | 2008 | 计算机光盘软件与应用(COMPUTER ARTS数码艺术)2008，，5： | 0 |
| 20 | 妙用《金山网镖》二三招显示文摘木马和病毒日益猖獗,很多用户都用防火墙用来抵挡这些来自互联网的不安全因素。安装完防火墙之后就万事大吉了吗?其实不然。防火墙所提供的全部功能,很多用户用到的不过25%,“千里马常有,而伯乐不常有”的现象在现实生活中出现了。 | pixy | 2005 | 计算机应用文摘2005，，20： | 0 |
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