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| 1 | MRI versus 64-row MDCT for diagnosis of hepatocellular carcinoma显示文摘AIM:To compare the diagnostic capability of multidetector computed tomography(MDCT) and magnetic resonance imaging(MRI) for the detection of hepatocellular carcinoma(HCC) tumour nodules and their effect on patient management.METHODS:A total of 28 patients(25 male,3 female,mean age 67±10.8 years) with biopsy-proven HCC were investigated with 64-row MDCT(slice 3 mm native,arterial and portal-venous phase,120 mL Iomeprol,4 mL/s,delay by bolus trigger) and MRI(T1fs fl2d TE/ TR 2.72/129 ms,T2tse TE/TR 102/4000 ms,5-phase dynamic contrast-enhanced T1fs fl3d TE/TR 1.56/4.6,Gadolinium-DTPA,slice 4 mm).Consensus reading of both modalities was used as reference.Tumour nodules were analyzed with respect to number,size,and location.RESULTS:In total,162 tumour nodules were detected by consensus reading.MRI detected signifi cantly more tumour nodules(159 vs 123,P<0.001) compared to MDCT,with the best sensitivity for early arterial phase MRI.False-negative CT findings included nodules ≤5 mm(n=5),≤10 mm(n=17),≤15 mm(n=12),≤20 mm(n=4),and 1 nodule >20 mm.MRI missed 2 nodules ≤10 mm and 1 nodule ≤15 mm.On MRI,nodule diameters were greater than on CT(29.2±25.1 mm,range 5-140 mm vs 24.1±22.7 mm,range 4-129 mm,P<0.005).In 2 patients,MDCT showed only unilobar tumour spread,whereas MRI revealed additional nodules in the contralateral lobe.Detection of these nodules could have changed the therapeutic strategy.CONCLUSION:Contrast-enhanced MRI is superior to 64-row MDCT for the detection of HCC nodules.Patients should be allocated to interventional or operative treatment according to a dedicated MRI-protocol. | Michael Bernhard Pitton Roman Kloeckner Sascha Herber Gerd Otto Karl Friedrich Kreitner Christoph Dueber | 2009 | World Journal of Gastroenterology2009，15，48： | 5 |
| 2 | Liver transplantation and BCLC classification:Limitations impede optimum treatment显示文摘Background:The Barcelona Clinic Liver Cancer(BCLC)system has been endorsed by international guidelines as a staging algorithm of hepatocellular carcinoma.This analysis was performed to assess the outcome of liver transplantation in patients treated against the BCLC recommendations.Methods:The data of 198 patients who underwent liver transplantation for hepatocellular carcinoma were extracted from a prospectively maintained database to classify the patients according to the BCLC system.Results:BCLC staging was as follows:0,n=5;A,n=77;B,n=41;C,n=53;and D,n=22.Accordingly,liver transplantation was performed in the majority of patients against BCLC recommendations.Surgery(n=16),radiofrequency ablation(n=15)and transarterial chemoembolization(n=151)preceded liver transplantation in 182 patients.Sixteen patients were transplanted without pretreatment.The 1-,5-and 10-year survival rates were 83.8%,62.4%and 45.9%,and 1-,5-,and 10-year recurrence rates were 7.7%,22.7%and 26.7%.The BCLC classification did neither impact survival(P=0.796)nor recurrence(P=0.693).In the Cox analysis,RECIST tumor progression and initial alpha fetoprotein were independent predictors of outcome.Conclusions:Neither the oncological nor the functional stratification imposed by the BCLC system was of importance for outcome.Lack of flexibility and disregard of biological parameters hamper its clinical applicability in liver transplantation. | Gerd Otto Michael B Pitton Maria Hoppe-Lotichius Arndt Weinmann | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，1： | 4 |
| 3 | Rapid percutaneous thrombectomy: final results from a prospective multicenter evaluation of a rheolytic catheter 显示文摘 | Wagner HJ Mueller-Huelsbeck S Pitton MB | 1996 | Radiology1996，9，： | 2 |
| 4 | Visceral artery aneurysms: Incidence, management, and outcome analysis in a tertiary care center over one decade 显示文摘 | Pitton MB Dappa E Jungmann F | 2015 | EurRadiol2015，25，7： | 1 |
| 5 | Indirect MR-arthrography in the follow up of autologous osteochondral transplantation显示文摘 | Herber S Runkel M Pitton M B | 2003 | Rofo2003，175，2： | 1 |
| 6 | Endovascular therapy of abdominal aortic aneurysm:results of a mid-term follow-up显示文摘 | Pitton MB Schweitzer H Herber S | 2003 | Rofo2003，175，10： | 1 |
| 7 | Hypertrophic Obstructive Cardio - myopathy and pregnancy anesthesiol ogical observations and clinical seties显示文摘 | Pitton MA Petolillo M Munegato E | 2007 | Minerva Anestesiol[ J]2007，73，5： | 1 |
| 8 | Radiofrequency Ablation as First-Line Treatment in Patients With Early Colorectal Liver Metastases Amenable to Surgery显示文摘 | Gerd Otto Christoph Düber Maria Hoppe-Lotichius Jochem K?nig Michael Heise Michael Bernhard Pitton | 2010 | Annals of Surgery2010，，5： | 1 |
| 9 | Long-term follow-up afterendovascular treatment of acute aortic emergencies显示文摘 | Pitton M B Herber S Schmiedt W | 2008 | Cardiovasc In-tervent Radiol2008，31，1： | 1 |
| 10 | Endovascular carotid reconstruction in palliative head and neck cancer patients with threatened carotid blowout presents a beneficial supportive care measure显示文摘 | KOUTSIMPELAS D PITTON M KULKENS C | 2008 | J Palliat Med2008，11，： | 1 |
| 11 | Cardiac troponin 1,cardiac troponin T and creatine kinase MB concentrations in umbilical cord blood of healthy term neonates显示文摘 | Trevisanuto D Pitton M Altinier S | 2003 | Acta Paediatr2003，92，12： | 1 |
| 12 | Chemoembolization for primary liver cancer显示文摘 | Achenbaeh T Seifert JK Pitton MB | 2002 | Eur J Surg Oncol2002，28，1： | 1 |
| 13 | CT-guided vertebroplasty in osteoporotic vertebral fractures:incidence of secondary fractures and impact of intradiscal cement leakages during follow-up显示文摘 | Pitton MB Herber S Bletz C et a1 | | 0，，01： | 1 |
| 14 | The role of pericardiectomy in pericardial disorders显示文摘 | HEHRLEIN F W MOOSDORF R PITTON M | 1991 | Eur Heart J1991，12，： | 1 |
| 15 | CT angiography versus intraarterial digital subtraction angiography for assessment of aortoiliac occlusive disease显示文摘 | Rieker O Duber C Pitton M | 1997 | AJR1997，169，4： | 1 |
| 16 | Prospective Randomized Study of Doxorubicin-Eluting-Bead Embolization in the Treatment of Hepatocellular Carcinoma: Results of the PRECISION V Study显示文摘 | Johannes Lammer Katarina Malagari Thomas Vogl Frank Pilleul Alban Denys Anthony Watkinson Michael Pitton Geraldine Sergent Thomas Pfammatter Sylvain Terraz Yves Benhamou Yves Avajon Thomas Gruenberger Maria Pomoni Herbert Langenberger Marcus Schuchmann Je | 2010 | CardioVascular and Interventional Radiology2010，，1： | 1 |
| 17 | Long- term follow- up af- ter endovascular treatment of acute aortic emergencies显示文摘 | Pitton MB Herber S Schmiedt W | 2008 | Cardio- vase Intervent Radiol2008，31，1： | 1 |
| 18 | Long-term follow-up after endovascular treatment of acute emergencies显示文摘 | Pitton MB Herber S Schmiedt W | | 0，，： | 1 |
| 19 | Vertebroplasty of ostero-portic vertebral fractures: New adjacent and distant fractures during follow-up显示文摘 | Pitton MB Herber S Morgen N | 2006 | Euro Radiology2006，，： | 1 |
| 20 | Height gain of vertebral bodies and stabilization of vertebral geometry over one year after vertebroplasty of osteoporotic vertebral fractures 显示文摘 | Pitton MB Morgen N Herber S | 2008 | Eur Radiol2008，18，3： | 1 |
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