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| 1 | Nanosecond mid-infrared pulse generation via modulated thermal emissivity显示文摘We demonstrate the generation of nanosecond mid-infrared pulses via fast modulation of thermal emissivity enabled by the absorption of visible pump pulses in unpatterned silicon and gallium arsenide.The free-carrier dynamics in these materials result in nanosecond-scale modulation of thermal emissivity,which leads to nanosecond pulsed thermal emission.To our knowledge,the nanosecond thermal-emissivity modulation in this work is three orders of magnitude faster than what has been previously demonstrated.We also indirectly observed subnanosecond thermal pulses from hot carriers in semiconductors.The experiments are well described by our multiphysics model.Our method of converting visible pulses into the mid infrared using modulated emissivity obeys different scaling laws and can have significant wavelength tunability compared to approaches based on conventional nonlinearities. | Yuzhe Xiao Nicholas A.Charipar Jad Salman Alberto Pique Mikhail A.Kats | 2019 | Light(Science & Applications)2019，8，1： | 4 |
| 2 | New genes emerging for colorectal cancer predisposition显示文摘Colorectal cancer(CRC)is one of the most frequent neoplasms and an important cause of mortality in the developed world.This cancer is caused by both genetic and environmental factors although 35%of the variation in CRC susceptibility involves inherited genetic differences.Mendelian syndromes account for about5%of the total burden of CRC,with Lynch syndrome and familial adenomatous polyposis the most common forms.Excluding hereditary forms,there is an important fraction of CRC cases that present familial aggregation for the disease with an unknown germline genetic cause.CRC can be also considered as a complex disease taking into account the common diseasecommom variant hypothesis with a polygenic model of inheritance where the genetic components of common complex diseases correspond mostly to variants of low/moderate effect.So far,30 common,low-penetrance susceptibility variants have been identified for CRC.Recently,new sequencing technologies including exomeand whole-genome sequencing have permitted to add a new approach to facilitate the identification of new genes responsible for human disease predisposition.By using whole-genome sequencing,germline mutations in the POLE and POLD1 genes have been found to be responsible for a new form of CRC genetic predisposition called polymerase proofreading-associated polyposis. | Clara Esteban-Jurado Pilar Garre Maria Vila Juan José Lozano Anna Pristoupilova Sergi Beltrán Anna Abulí Jenifer Muoz Francesc Balaguer Teresa Ocaa Antoni Castells Josep M Piqué Angel Carracedo Clara Ruiz-Ponte Xavier Bessa Montserrat Andreu Luis Bujanda Trinidad Caldés Sergi Castellví-Bel | 2014 | World Journal of Gastroenterology2014，20，8： | 3 |
| 3 | Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial显示文摘 | Antonio M Lacy Juan C García-Valdecasas Salvadora Delgado Antoni Castells Pilar Taurá Josep M Piqué Josep Visa | 2002 | 2002 (9325)2002，，9325： | 3 |
| 4 | Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial显示文摘 | Antonio M Lacy Juan C García-Valdecasas Salvadora Delgado Antoni Castells Pilar Taurá Josep M Piqué Josep Visa | 2002 | The Lancet2002，，9325： | 2 |
| 5 | The Long-term Results of a Randomized Clinical Trial of Laparoscopy-assisted Versus Open Surgery for Colon Cancer显示文摘 | Antonio M. Lacy Salvadora Delgado Antoni Castells Hubert A. Prins Vicente Arroyo Ainitze Ibarzabal Josep M. Pique | 2008 | Annals of Surgery2008，，1： | 2 |
| 6 | Crack initiation and propagation under multiaxial fatigue in a natural rubber显示文摘 | N. Saintier G. Cailletaud R. Piques | 2005 | International Journal of Fatigue2005，，1： | 2 |
| 7 | Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial显示文摘 | Antonio M Lacy Juan C García-Valdecasas Salvadora Delgado Antoni Castells Pilar Taurá Josep M Piqué Josep Visa | 2002 | The Lancet2002，，9325： | 2 |
| 8 | Aspirin and salicylate induced apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells显示文摘 | Bellosillo B Pique M Barragan M Castano E Villamor N Colomer D | 1998 | Blood1998，92，： | 1 |
| 9 | Effect of bolus injection and continuous infusion of somatostafin on gastric perfusion in cirrhotic patients with portal - hypertensive gastropathy显示文摘 | Panes J Pique JM Bordas JM | 1994 | Hepatology1994，20，： | 1 |
| 10 | Portal hypertensive gastropathy显示文摘 | Pique JM | 1997 | Baillieres Clin Gastroenterol1997，11，： | 1 |
| 11 | Influence of cold-storage conditions on the quality of unshelled walnuts显示文摘 | Lopez A Pique M T Romero A | 1995 | Int J Refrig1995，18，8： | 1 |
| 12 | Multiaxial Fatigue Life Prediction for a Natural Rubber显示文摘 | Saintier N Cailletaud G Piques R | 2006 | International Journal of Fatigue2006，28，10： | 1 |
| 13 | Effect of Aluminum Doping on Zinc Oxide Thin Films Grown by Pulsed Laser Deposition for Organic Light-emitting Devices显示文摘 | Kim H Pique A Horwitz J S | 2000 | Thin Solid Films2000，，： | 1 |
| 14 | Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition 显示文摘 | Pizcueta P Pique JM Fernandez M | 1992 | Gastroenterology1992，103，6： | 1 |
| 15 | Propranolo in prevention of recurrent bleeding from serere portal hypertensive gastropathy in cirrhosis显示文摘 | Peroz-Ayoso R Pique J Bosch J | 1991 | Lancet1991，337，8755： | 1 |
| 16 | Effect of aluminum doping on zinc oxide thin films grown by pulsed laser deposition for organic light emitting devices 显示文摘 | Kim H Pique A Horwitz J S | 2000 | Thin Solid Films2000，，1： | 1 |
| 17 | Effect of bolus injection and continuous infusion of somatostatin of gastric perfusion in cirrhotic patients with portal hypertensive gastropathy显示文摘 | Panes J Pique JM Bordos JM | 1994 | Hepatology1994，20，2： | 1 |
| 18 | Influence of cold storage conditions on the quality of unshelled Walnuts显示文摘 | Lopez A Pique A T Romero A | 1995 | Int J Refrig1995，18，8： | 1 |
| 19 | Laser processing of polymer thin films for chemical sensor applications显示文摘 | Piqué A Auyeung R C Y | 2003 | Surf Coat Techn2003，，： | 1 |
| 20 | A Multicenter, Randomized, Clinical Trial of Hormonal Therapy in the Prevention of Rebleeding From Gastrointestinal Angiodysplasia显示文摘 | Félix Junquera Faust Feu Michel Papo Sebastián Videla José Ramón Armengol Josep Mar??a Bordas Esteban Saperas Josep M. Piqué Juan-Ramón Malagelada | 2001 | Gastroenterology2001，，5： | 1 |
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