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| 1 | iCAP TQ ICP-MS准确测定环境样品中的砷和硒显示文摘本文介绍了Thermo Scientific TM iCAPTM TQ ICP-MS定量检测含稀土元素样品中砷和硒的方法,评估三重四极杆(TQ)-ICP-MS测量模式的性能,并与单四极杆(SQ)ICP-MS测量模式进行比较.为了验证方法的稳定性和准确性,在最佳参数条件下分析了深海沉积物和地球化学参考标准这两个样品. | Marcus Manecki Simon Lofthouse Philipp Boening Shona McSheehy Ducos | 2017 | 环境化学2017，36，12： | 11 |
| 2 | 1999~2006年急性冠脉综合征患者死亡及心力衰竭发生率降低显示文摘背景:有关药物和介入治疗对ST段抬高型和非ST段抬高型急性冠脉综合征(non—ST-segment elevation acute coronary syndrome,NSTE ACS)患者的作用,随机试验已经提供了足够的证据,但是是否已经转化为相应的临床变化还不清楚。
目的:确定ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)和NSTE ACS患者的院内治疗改变是否伴随临床结果的改善。
设计、地点及患者:全球急性冠脉事件注册研究(Global Registry of Acute Coronary Events,GRACE)是一项多国家队列研究。自1999年7月1日至2006年12月31日,该研究共入选并随访了来自14个国家、113家医院的44372例ACS患者。
主要观测指标:当前循证药物和介入治疗应用的趋势及患者预后(死亡、充血性心力衰竭、肺水肿、心源性休克、卒中和心肌梗死)。
结果:随着研究时间的进展,相关药物的应用增加(β-受体阻滞剂、他汀类药物、血管紧张素转换酶抑制剂、行或未行经皮冠状动脉介入治疗[percutaneous coronary intervention,PCI]患者应用噻氯毗啶、糖蛋白Ⅱb/Ⅲa抑制剂和低分子肝素;P〈0.001)。STEMI患者药物再灌注治疗下降了22个百分点(95%可信区间[confidence interval,CI],-27~-17),而直接PCI增加了37个百分点(95%CI,33—41)。在NSTEMI患者中,PCI的比例显著升高了18个百分点(95%CI,15~20)。充血性心力衰竭和肺水肿在STEMI患者中降低了9个百分点(95%CI,-12~-6),在NSTEACS患者中降低了6.9个百分点(95%CI,-8.4~-4.7)。STEMI患者的院内死亡率降低了18个百分点(95%CI,-5.3~-1.9),心源性休克降低了24个百分点(95%CI,-4.3~-0.5)。校正了危险评分后,NSTEACS患者的院内死亡率降低了0.7个百分点(95%CI,-1.7~0.3);STEMI患者6个月随访时卒中发生率降低了0.8个百分点(95%CI,-1.7~0.1),心肌梗死发生率降低了2.8个百分点(95%CI,-6.4~0.9)。NSTEACS患者6个月死亡率降低了1.6个百分点(95%CI,-3.0~-0.1),卒中发生率降低了0.7个百分点(95%CI,-1.4~0.1)。
结论:在本项多国家观察性研究中,ACS患者治疗的改善与6个月新发心力衰竭、死亡率、卒中和心肌梗死发生率显著降低相关。 | Keith A. A. Fox Philippe Gabriel Steg Kim A. Eagle Shaun G. Goodman Frederick A. Anderson Christopher B. Granger Marcus D. Flather Andrzej Budaj Ann Quill Joel M. Gore 康俊萍(译) 马长生(校) | 2007 | 美国医学会杂志(中文版)2007，26，6： | 6 |
| 3 | Plasma-CVD-coated glass beads as photocatalyst for water decontamination显示文摘 | Martin Karches Marcus Morstein Philipp Rudolf von Rohr | 2002 | Catalysis Today2002，72，： | 1 |
| 4 | Nucleation and growth of oxide layers on stainless steels (Fe Cr) using a layer model 显示文摘 | Boubakar Diawara Yves Alain Beh Philippe Marcus | 2010 | Journal of Physical Chemistry C2010，，19： | 1 |
| 5 | 多环芳烃的慢性暴露对人体皮肤微生物菌群的影响显示文摘多环芳烃(PAHS)是一类可通过吸入、食入和经皮吸收的方式进入体内和血液循环中的有机污染物,常常存在于大气的颗粒物中。虽然已知皮肤对PAHs的慢性暴露可能与皮肤的过早老化、色素沉着、痤疮和皮肤肿瘤有关,但我们对其确切机制仍缺乏了解。与此同时,随着皮肤表面微生物菌群对宿主皮肤健康影响的研究不断深人,有研究证实皮肤共生菌群可降解不同的PAHs及与其相关的外源性成分。由于PAHs暴露与皮肤微生态之间可能存在潜在关联,因此有必要进一步探索PAHs对皮肤微生物菌群的影响机制。 | Marcus L Xinzhao T Philippe B | 2021 | 中华皮肤科杂志2021，54，4： | 1 |
| 6 | Estimation of the parameters of oxide film growth on nickel-based alloys in high-temperature water electrolytes显示文摘 | Martin Bojinov Anouk Galtayries Petri Kinnunen Alexandre Machet Philippe Marcus | 2007 | Electrochimica Acta2007，，26： | 1 |
| 7 | Corrosion protection of magnesium alloys by cerium, zirconium and niobium-based conversion coatings显示文摘 | Hélène Ardelean Isabelle Frateur Philippe Marcus | 2008 | Corrosion Science2008，，7： | 1 |
| 8 | Sepsis - associated encephalopathy: a magnetic resonance imaging and speetroscopy study显示文摘 | Fernando AB Philippe G Marcus FO | 2010 | J Cereb Blood Flow Metab2010，30，2： | 1 |
| 9 | Dynamic multi-section CT imaging in acute myocardial infarction: preliminary animal experience显示文摘 | Andreas H. Mahnken Philipp Bruners Marcus Katoh Joachim E. Wildberger Rolf W. Günther Arno Buecker | 2006 | European Radiology2006，，3： | 1 |
| 10 | Estimation of the parameters of oxide film growth on nickel-based alloys in high-temperature water electrolytes显示文摘 | Martin Bojinov Anouk Galtayries Petri Kinnunen Alexandre Machet Philippe Marcus | 2007 | Electrochimica Acta2007，，26： | 1 |
| 11 | Imaging of the scrotum in children 显示文摘 | Marcus Hrmann Csilla Balassy Marcel Philipp | 2004 | Eur Radiol2004，14，6： | 1 |
| 12 | High rate of complete histopathological response in hepatocellular carcinoma patients after combined transarterial chemoembolization and stereotactic body radiation therapy显示文摘BACKGROUND Liver transplantation(LT)presents a curative treatment option in patients with early stage hepatocellular carcinoma(HCC)who are not eligible for resection or ablation therapy.Due to a risk of up 30%for waitlist drop-out upon tumor progression,bridging therapies are used to halt tumor growth.Transarterial chemoembolization(TACE)and less commonly stereotactic body radiation therapy(SBRT)or a combination of TACE and SBRT,are used as bridging therapies in LT.However,it remains unclear if one of those treatment options is superior.The analysis of explant livers after transplantation provides the unique opportunity to investigate treatment response by histopathology.AIM To analyze histopathological response to a combination of TACE and SBRT in HCC in comparison to TACE or SBRT alone.METHODS In this multicenter retrospective study,27 patients who received liver transplantation for HCC were analyzed.Patients received either TACE or SBRT alone,or a combination of TACE and SBRT as bridging therapy to liver transplantation.Liver explants of all patients who received at least one TACE and/or SBRT were analyzed for the presence of residual vital tumor tissue by histopathology to assess differences in treatment response to bridging therapies.Statistical analysis was performed using Fisher-Freeman-Halton exact test,Kruskal-Wallis and Mann-Whitney-U tests.RESULTS Fourteen patients received TACE only,four patients SBRT only,and nine patients a combination therapy of TACE and SBRT.There were no significant differences between groups regarding age,sex,etiology of underlying liver disease or number and size of tumor lesions.Strikingly,analysis of liver explants revealed that almost all patients in the TACE and SBRT combination group(8/9,89%)showed no residual vital tumor tissue by histopathology,whereas TACE or SBRT alone resulted in significantly lower rates of complete histopathological response(0/14,0%and 1/4,25%,respectively,P value<0.001).CONCLUSION Our data suggests that a combination of TACE and SBRT increases the rate of complete histopathological response compared to TACE or SBRT alone in bridging to liver transplantation. | Ulrike Bauer Sabine Gerum Falk Roeder Stefan Münch Stephanie E Combs Alexander B Philipp Enrico N De Toni Martha M Kirstein Arndt Vogel Carolin Mogler Bernhard Haller Jens Neumann Rickmer F Braren Marcus R Makowski Philipp Paprottka Markus Guba Fabian Geisler Roland M Schmid Andreas Umgelter Ursula Ehmer | 2021 | World Journal of Gastroenterology2021，27，24： | 1 |
| 13 | Advanced protection against environmental degradation of silver mirror stacks for space application显示文摘Protection of silver mirror stacks from environmental degradation before launching is crucial for space applications.Hereby,we report a comparative study of the advanced protection of silver mirror stacks for space telescopes provided by SiO_(2)and Al_(2)O_(3)coatings in conditions of accelerated aging by sulfida-tion.The model silver stack samples were deposited by cathodic magnetron sputtering on a reference silica substrate for optical applications and a surface-pretreated SiC substrate.Accelerated aging was per-formed in dry and more severe wet conditions.Optical micrographic observations,surface and interface analysis by Time-of Flight Secondary Ion Mass Spectrometry(ToF-SIMS)and reflectivity measurements were combined to comparatively study the effects of degradation.The results show a lower kinetics of degradation by accelerated aging of the stacks protected by the alumina coating in comparable test conditions. | Rajendra Kurapati Vincent Maurice Antoine Seyeux Lorena H.Klein Dimitri Mercier Gregory Chauveau Catherine Grees-Besset Loic Berthod Philippe Marcus | 2021 | Journal of Materials Science & Technology2021，，5： | 1 |
| 14 | A Feasibility Study of Contrast Enhancement of Acute Myocardial Infarction in Multislice Computed Tomography: Comparison With Magnetic Resonance Imaging and Gross Morphology in Pigs显示文摘 | Arno Buecker Marcus Katoh Gabriele A. Krombach Elmar Spuentrup Philipp Bruners Rolf W. Günther Thoralf Niendorf Andreas H. Mahnken | 2005 | Investigative Radiology2005，，11： | 1 |
| 15 | Sepsis- associated encephalopathy : a magnetic resonance imaging and spectroscopy study 显示文摘 | Fernando AB Philippe G Marcus F | 2010 | Journal of Cerebral Blood Flow & Metabolism2010，30，： | 1 |
| 16 | Plasma-CVD-coated glass beads as photocatalyst for water decontamination显示文摘 | MARTIN KARCHES MARCUS MORSTEIN PHILIPP RUDOLF VON ROHR | 2002 | Catalysis Today2002，，72： | 1 |
| 17 | Plasma-CVD-coated glass beads as photocatalyst for water decontamination 显示文摘 | Martin Karchesa Marcus Morsteinb Philipp Rudolf yon Rohra | 2002 | Catalysis Today2002，72，34： | 1 |
| 18 | Preoperative mapping of cortical motor function: prospective comparison of functional magnetic resonance imaging and (150)-H2O-positron emission tomography in the same coordinate system显示文摘 | Marcus HT Reingesa TK Philipp T | 2004 | Nuclear Medicine Communications2004，25，： | 1 |
| 19 | Biomechanical analysis of the three-dimensional motion pattern of the canine cervical spine segment C4-C5显示文摘 | Martin Hofstetter Philippe Gedet Marcus Doherr | | 0，，： | 1 |
| 20 | Validation of Several SUV-Based Parameters Derived from 18F-FDG PET for Prediction of Survival After SIRT of Hepatic Metastases from Colorectal Cancer显示文摘 | Wolfgang Peter Fendler Donfack Beauclair Philippe Tiega Harun Ilhan Philipp M. Paprottka Volker Heinemann Tobias F. Jakobs Peter Bartenstein Marcus Hacker Alexander Robert Haug | 2013 | Journal of Nuclear Medicine2013，，8： | 1 |
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