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| 1 | Critical role of SDF-1/CXCR4 signaling pathway in stem cell homing in the deafened rat cochlea after acoustic trauma显示文摘Previous animal studies have shown that stromal cell-derived factor-1(SDF-1)/CXC chemokine receptor-4(CXCR4) signaling pathway plays an important role in the targeted migration of bone marrow-derived mesenchymal stem cells(BMSCs) to the injured area. In the present study, we aimed to investigate the potential role of chemotactic SDF-1/CXCR4 signaling pathway in the homing of transplanted BMSCs to the injured cochlea after noise-induced hearing loss(NIHL) in a rat model. White noise exposure(110 d B) paradigm was used for hearing loss induction in male rats for 6 hours in 5 days. Distortion-product otoacoustic emission(DPOAE) responses were recorded before the experiment and post noise exposure. Hoechst 33342-labeled BMSCs and CXCR4 antagonist(AMD3100)-treated BMSCs were injected into the rat cochlea through the round window. SDF-1 protein expression in the cochlear tissue was assayed using western blot assay. The number of labeled BMSCs reaching the endolymph was determined after 24 hours. SDF-1 was significantly increased in the cochlear tissue of rats in the noise exposure group than in the control group. The number of Hoechst 33342-labeled BMSCs reaching the endolymph of the cochlea was significantly smaller in the AMD3100-treated BMSCs group than in the normal BMSCs group. Our present findings suggest that the SDF-1/CXCR4 signaling pathway has a critical role in BMSCs migration to the injured cochlea in a rat model of noise-induced hearing loss. | Ali Asghar Peyvandi Navid Ahmady Roozbahany Hassan Peyvandi Hojjat-Allah Abbaszadeh Niloofar Majdinasab Mohammad Faridan Somayeh Niknazar | 2018 | Neural Regeneration Research2018，13，1： | 11 |
| 2 | A New Self-Loading Locomotion Mechanism for Wall Climbing Robots Employing Biomimetic Adhesives显示文摘 | Amirpasha Peyvandi Parviz Soroushian Jue Lu | 2013 | Journal of Bionic Engineering2013，10，1： | 7 |
| 3 | 针刺对体外受精结局的影响(英文)显示文摘目的:本研究旨在评价针灸对于体外受精结局的影响。方法:纳入2009-2010年间来Khomeini医院就诊的164名接受试管婴儿辅助生育的妇女。分为针灸组82例,对照组82例。针灸组在取卵当天、取卵后2日和胚胎移植前百会、腰阳关、太冲、内关、三阴交、归来、足三里、合谷以及耳穴内生殖器和神门进行针灸治疗,对照组不接受针灸治疗。比较两组的受孕阳性试验、临床怀孕和保胎能力。结果:针灸组受孕34例(41.5%),对照组21例(25.6%),两组差别有统计学意义(P<0.05);针灸组第五周可见孕囊人数为31例(37.8%),对照组为17例(20.7%),两组差别有统计学意义(P<0.05);12周后怀孕人数针灸组和对照组分别为21(21.6%)and 12(14.6%),两组差别无统计学意义(P>0.05)。结论:针灸可以提高体外受精成功率。 | Sepideh Peyvandi Samaneh Rokhgireh Nadali Esmaeeli | 2016 | World Journal of Acupuncture-Moxibustion2016，26，3： | 5 |
| 4 | CYP2C9 genotypes and does requirements during the induction phase of oral anticogulant therapy显示文摘 | PEYVANDI F SPREAFICO M SIBONI S M | 2004 | Clin Pharmacol Ther2004，75，3： | 1 |
| 5 | Preconceptual Folic Acid Use and Recurrence Risk Counseling for Congenital Heart Disease显示文摘 | Peyvandi S Rychik J Zhang X | 2014 | Congenit Heart Dis2014，24，7： | 1 |
| 6 | Granulomatous lobular mastitis : imaging, diagnosis, andtreatment显示文摘 | Hovanessian Larsen LJ Peyvandi B Klipfel N | 2009 | Am J Roentgenol2009，193，2： | 1 |
| 7 | Pathogenesis and treatment of ac- quired idiopathic thrombotic thrombocytopenic purpura 显示文摘 | Peyvandi F Palla R Lotta LA | 2010 | Hae- matologica2010，95，9： | 1 |
| 8 | The thrombospondin- N700S polymorphism is associated with early myocardial in显示文摘 | Zwicker JI Peyvandi F Palla R | 2006 | Blood2006，108，4： | 1 |
| 9 | Granuloma- tous lobular mastitis: imaging, diagnosis, and treatment显示文摘 | Hovanessian Larsen Id Peyvandi B Klipfel N | 2009 | Am J Roentgenol2009，193，2： | 1 |
| 10 | Procoagulant Imbalance in Patients with Nonalcoholic Fatty Liver Disease显示文摘 | Armando Tripodi Anna L. Fracanzani Massimo Primignani Veena Chantarangkul Marigrazia Clerici Pier Mannuccio Mannucci Flora Peyvandi Cristina Bertelli Luca Valenti Silvia Fargion | 2014 | Journal of Hepatology2014，，： | 1 |
| 11 | Rare bleeding disorders:diagnosis and treatment显示文摘 | Palla R Peyvandi F Shapiro AD | 2015 | Blood2015，125，13： | 1 |
| 12 | Dosing anticoagulant therapy with coumarin drugs: is genotypingclinically useful? No显示文摘 | MANNUCCI PM SPREAFICO M PEYVANDI F | 2008 | J Thromb Haemost2008，9，1： | 1 |
| 13 | ADAMTS-13 assays in thrombotic thrombocytopenic purpura 显示文摘 | Peyvandi F Palla R Lotta LA et aI | 2010 | J Thromb Haemost2010，8，4： | 1 |
| 14 | Dosing anticoagulant therapy with eoumarin drugs: is genotyping elinicaiIy useful? No 显示文摘 | Mannucei PM Spreafieo M Peyvandi F | 2008 | J Thromh Haemost2008，6，9： | 1 |
| 15 | Granulomatous lobular mastitis: imaging, diagnosis, and treatment显示文摘 | Hovanessian Larsen LJ Peyvandi B Klipfel N | 2009 | A JR Am J Roentgenol2009，193，2： | 1 |
| 16 | Incidence of bleeding symptoms in 100 patients with inherited afibrinogenemia or hypofibrinogenemia显示文摘 | Peyvandi F Haertel S Knaub S | 2006 | J Thromb Haemost2006，4，7： | 1 |
| 17 | Fibrinogen replacement therapy for congenital fibrinogen deficiency显示文摘 | Bomikova L Peyvandi F Allen G | 2011 | J Thromb Haemost2011，9，： | 1 |
| 18 | Granuloma- tous lobular mastitis: imaging, diagnosis, and treatment 显示文摘 | Hovanessian Larsen LJ Peyvandi B Klifel N | 2009 | A JR2009，193，2： | 1 |
| 19 | Strong association of the APOA5 -1131T>C gene variant and early-onset acute myocardial infarction显示文摘 | Raffaele De Caterina Philippa J. Talmud Piera Angelica Merlini Luisa Foco Roberta Pastorino David Altshuler Francesco Mauri Flora Peyvandi Daniela Lina Sekar Kathiresan Luisa Bernardinelli Diego Ardissino | 2010 | Atherosclerosis2010，，2： | 1 |
| 20 | Pathogenesis and treatment of acquired idiopathic thrombotic thrombocytopenic purpura显示文摘 | Peyvandi F Palla R Lotta LA | 2010 | Haematologica2010，95，9： | 1 |
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