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| 1 | Erectile dysfunction and central obesity: an Italian perspective显示文摘可勃起的机能障碍(编辑) 是肥胖的经常的复杂并发症。这评论的目的是极其分析肥胖和编辑的框架,把在二个病理学的实体之间的连接。当前的临床的证据显示出那肥胖,和特别地中央的肥胖,与两个 arteriogenic 版本被联系并且减少了睾丸激素(T) 层次。联系肥胖的性腺机能减退和增加的心血管的风险可能部分在超重、肥胖的个人认为编辑的更高的流行正当,是想得到的。相反地,与肥胖有关的心理骚乱不似乎然而在肥胖相关的编辑的致病起一个主要作用,在编辑之间的协会和内脏的胖累积从已知的联系肥胖的 comorbidities 是独立的临床、现出症状之前的潜的数据表演。因此,内脏的脂肪怎么能损害阴茎 microcirculation,仍然保持未知。自从在编辑题目的中央肥胖在高心血管的风险分类个人,这个点是特别地相关的,特别在最年轻的。在肥胖的题目的编辑的存在可能在说服他们开始一个善良的周期帮助保健专业人员,在性机能障碍的修正将是为改进生活方式行为的报酬的地方。Unsatisfying 性活动为请教接着,应该利用机会鼓励肥胖的病人对待的保健专业版代表有意义的、直接动机,除编辑以外,内在的相反的条件,这样不仅恢复可勃起的功能,而且全面健康。 | Giovanni Corona Giulia Rastrelli Sandra Filippi Linda Vignozzi Edoardo Mannucci Mario Maggi | 2014 | Asian Journal of Andrology2014，16，4： | 9 |
| 2 | How to recognize late-onset hypogonadism in men wit sexual dysfunction显示文摘迟了发作的性腺机能减退(LOH ) 在 100 个人与约 1 的流行被认为男性腺机能减退的最普通的形式。LOH 的诊断应该与不含糊地低的浆液睾丸激素(T) 层次在征兆的人被做。然而,因为它被与生理的变老做微分诊断的 nonspecific 症状描绘,它的临床的演讲经常暗中为害、困难认出有问题。性机能障碍是为医药会诊和与低 T 联系的最特定的症状的最重要的决定因素。我们因此分析了出席了我们的单位的 1734 个题目的一个连续系列因为调查在低 T (不同阀值) 之间的协会的性机能障碍,性参数,病历数据(推迟的发身,垂体疾病或 cryptorchidism ) 和他们的物理考试结果。新陈代谢的参数,特别地腰圆周,在检测低 T 显示最大的精确性。我们发现仅仅几症状和符号的协会能显著地提起低 T 的临床的怀疑。结构化的库存,一起聚类性腺机能减退的症状和症状,能帮助临床医生怀疑雄激素缺乏。特别地,组织了会见,例如 ANDROTEST,被表明了有更大的精确性什么时候在检测低 T 与自我相比报导了问询表,铺平。 | Giovanni Corona Giulia Rastrelli Linda Vignozzi Edoardo Mannucci Mario Maggi | 2012 | Asian Journal of Andrology2012，14，2： | 3 |
| 3 | Colorectal cancer screening from 45 years of age: Thesis, antithesis and synthesis显示文摘Colorectal cancer incidence and mortality in patients younger than 50 years are increasing, but screening before the age of 50 is not offered in Europe. Advancedstage diagnosis and mortality from colorectal cancer before 50 years of age are increasing. This is not a detection-bias effect;it is a real issue affecting the entire population. Three independent computational models indicate that screening from 45 years of age would yield a better balance of benefits and risks than the current start at 50 years of age. Experimental data support these predictions in a sex- and race-independent manner. Earlier screening is seemingly affordable, with minimal impediments to providing younger adults with colonoscopy. Indeed, the American Cancer Society has already started to recommend screening from 45 years of age in the United States. Implementing early screening is a societal and public health problem. The three independent computational models that suggested earlier screening were criticized for assuming perfect compliance. Guidelines and recommendations should be derived from well-collected and reproducible data, and not from mathematical predictions. In the era of personalized medicine, screening decisions might not be based solely on age, and sophisticated prediction software may better guide screening. Moreover, early screening might divert resources away from older individuals with greater biological risks. Finally, it is still unknown whether early colorectal cancer is part of a continuum of disease or a biologically distinct disease and, as such, it might not benefit from screening at all. The increase in early-onset colorectal cancer incidence and mortality demonstrates an obligation to take actions. Earlier screening would save lives, and starting at the age of 45 years may be a robust screening option. | Alessandro Mannucci Raffaella Alessia Zuppardo Riccardo Rosati Milena Di Leo José Perea Giulia Martina Cavestro | 2019 | World Journal of Gastroenterology2019，25，21： | 2 |
| 4 | Applicability of the Arrhenius model for Ammonia Oxidizing Bacteria subjected to temperature time gradients显示文摘这个工作的目的是识别 Arrhenius 类型温度依赖的适用性的范围因为受到温度的氨氧化细菌(AOB ) 通过连续 titrimetric 测试预定坡度。一种创新联机微分 titrimetric 技术被用来连续地监视在一个飞行员规模膜生物反应器选择的生物资源的最大的生物学的氨氧化率,作为温度时间坡度的一个函数。监视技术在反应堆为 AOB 处于 nonlimiting 底层条件操作了的二平行基于碱度和氢过氧化物消费率的测量;反应堆连续地用混合白酒被喂,在他们之一, AOB 与 allylthiourea 被禁止。减少在范围评估的温度的效果 1 ~ 4 ? 圭 ? ??? 猯'T? 楔 ? ??? 猯'T ￣潰摷牥? | Alberto MANNUCCI Giulio MUNZ Gualtiero MORI Claudio LUBELLO Jan A. OLESZKIEWICZ | 2015 | Frontiers of Environmental Science & Engineering2015，9，6： | 2 |
| 5 | Orlistat and sibutramine beyond weight loss显示文摘 | MANNUCCI E DICEMBRINI I ROTELLA F | 2008 | Nutrition Metabolism & Cardiovascular Diseases2008，18，5： | 1 |
| 6 | Prevention of cardiovascular disease through glycemic control in type 2 diabetes: a meta-analysis of randomized clinical trials显示文摘 | Mannucci E Monami M Lamanna C | 2009 | Nutr Metab Cardiovasc Dis2009，19，9： | 1 |
| 7 | Low plateletalpha2beta1 levels in type I von Willebrand disease correlate withimpaired platelet function in a high shear stress system显示文摘 | Di Paola J Federici A B Mannucci P M | 1999 | Blood1999，93，11： | 1 |
| 8 | Multicentric evaluation of a new assay for prothrombin fragment F1 + 2 determination显示文摘 | Bruhn HD Conard J Mannucci M | 1992 | Thromb Haemost1992，68，4： | 1 |
| 9 | Cystatin C reference values and aging显示文摘 | Ognibene A Mannucci E Caldini A | | 0，，06： | 1 |
| 10 | APilot Study of Pro-urokinase in the Treatment of Deep Vein Thrombosis显示文摘 | Moia M Mannucci P M Pini M | 1994 | Thrombosis and Haemostasis1994，72，3： | 1 |
| 11 | Prevention of cardiovascular disease through glycemic control in type 2 diabetes:a meta-analysis of randomized clinical trials显示文摘 | Mannucci E Monami M Lamanna C | | Nutrition Metabolism and Cardiovascular Diseases0，，： | 1 |
| 12 | Anaerobic treatment ofvegetable tannery wastewaters:a review显示文摘 | Mannucci A Munz G Mori G | | 0，，1： | 1 |
| 13 | Adiponectin in outpatients with coronary artery disease: independent predictors and relationship with heart failure显示文摘 | Baldasseroni S Mannucci E Orso F | 2012 | Nutr Metab Cardiovasc Dis2012，22，3： | 1 |
| 14 | Long-acting insulin analogues versus NPH human insulin in type 2 diabetes a meta- analysis显示文摘 | Monami M Marchionni N Mannucci E | 2008 | Diabetes Res Clin Pract2008，81，2： | 1 |
| 15 | ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomedi- ated diseases显示文摘 | Rieger M Mannucci PM Kremer Hovinga JA Herzog A Ger- stenbauer G Konetschny C | 2005 | Blood2005，106，4： | 1 |
| 16 | Long-acting insulin analogues versus NPH human insulin in type 2 diabetes: a meta-analysis显示文摘 | Monami M Marchionni N Mannucci E | 2008 | Diabetes Res Clin Pract2008，81，： | 1 |
| 17 | Adiponectin in outpatients with coronary artery disease : independent predictors and relationship with heart failure 显示文摘 | Baldasseroni S Mannucci E Orso F | 2012 | Nutr Metab Cardiovasc Dis2012，22，3： | 1 |
| 18 | Psycho-biological cor- relates of free-floating anxiety symptoms in male patients with sexual dysfunctions显示文摘 | Corona G Mannucci E Petrone L | | J Androl0，27，1： | 1 |
| 19 | Dipeptidyl peptidase‐4 inhibitors and cardiovascular risk: a meta‐analysis of randomized clinical trials显示文摘 | M. Monami B. Ahrén I. Dicembrini E. Mannucci | 2012 | Diabetes Obes Metab2012，，： | 1 |
| 20 | Glucagon-like peptide 1 (GLP-1) and metabolic disease显示文摘 | Rotella CM Pala L Mannucci E | 2005 | J Endocrinol Invest2005，28，8： | 1 |
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