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| 1 | Serum levels of macrophage migration inhibitory factor,Interleukin-17 and Interleukin-10 in patients with HBV-related liver disease显示文摘Objective To study the potential role of macrophage migration inhibitory factor(MIF),Interleukin-17(IL-17) and Interleukin-10(IL-10) in the development of HBV-related liver disease.Methods 48 patients with chronic hepatitis B(HBeAg negative and positive,24 cases;21cases of HBV-DNA negative and 27 cases of HBV-DNA positive),81 cases of hepatitis B patients with decompensated cirrhosis and 48 cases of primary liver cancer patients were collected as the experimental group,26 healthy people were as control group.Serum MIF,IL-17 and IL-10 were measured.Results MIF and IL-17 significantly increased,IL-10 significantly decreased in experimental group,compared with the control group(P<0.05),there was significant difference.In addition,there was no significant difference(P>0.05) between positive and negative of chronic hepatitis B.MIF,IL-17 and ALT levels were positively correlated(r=0.693,P<0.01;r=0.897,P<0.001),IL-10 and ALT was negatively correlated(r =-0.285,P=0.037).Conclusion These results indicated that MIF,IL-17 and IL-10 may participate in the pathological process of HBV-related liver disease,serum levels of MIF,IL-17 and IL-10 appear to reflect the severity of tissue injury in HBV-related liver disease. | YU Xiaohui1,DUAN Huichun2,WEI Wang1 1.Department of Gastroenterology,Lanzhou General Hospital,Lanzhou Command,PLA,Lanzhou 730050 2.Department of Gastroenterology,General Hospital of Lanzhou Petrol Chemical Company,Chin | 2012 | 胃肠病学和肝病学杂志2012，21，6： | 10 |
| 2 | Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome显示文摘 | Petrol G Nanda A Howden J Takeichi T McMillan J R Aristodemou S | 2014 | Am J Hum Genet2014，95，： | 1 |
| 3 | Force modeling for cylindrical plunge cutting显示文摘 | Li Y Liang S Y Petrol R C | 2000 | The International Journal of Advanced Manufacturing Technology2000，16，12： | 1 |
| 4 | Expression of α-smooth muscle(α-SM) actin during corneal stromal wound healing显示文摘 | Jester JV Petroll WM Barry PA | 1995 | Invest Ophthalmol Vis Sci1995，36，： | 1 |
| 5 | Effect of myopic lasik on corneal sensitivity and morphology of subbasal nerves显示文摘 | Linna TU Vesaluoma MH Perez Santonja JJ Petroll WM Alio JL Tervo TM | 2000 | Invest Ophthalmol Vis Sci2000，41，3： | 1 |
| 6 | Corneal stromal wound healingin refractive surgery: the role of myofibroblasts显示文摘 | Jester JV Petroll WM Ca zanagh HD | 1999 | Prog Retin Eye Res1999，18，： | 1 |
| 7 | Corneal stromal changes induced by myopic LASIK invest显示文摘 | Vesaluoma m Perez-santonja j Petrol wm | 2000 | Ophthalmol vis sci2000，，： | 1 |
| 8 | TGF beta induced myofibroblast differentiation of rabbit keratocytes requires synergistic TGF β,PDGF and integrin signaling显示文摘 | Jester JV Huang JY Petroll WM | 2002 | Exp Eye Res2002，75，6： | 1 |
| 9 | Upper airway muscle inflammation and denervation changes in obstructive sleep apnea显示文摘 | Boyd JH Petrol BJ Hamid Q | 2004 | Am J Respir Crit Care Med2004，170，5： | 1 |
| 10 | Corneal stromal wound healingin refractive surgery: the role of myofibroblasts显示文摘 | Jester JV Petroll WM Cavanagh HD | 1999 | Prog Retin Eye Res1999，18，： | 1 |
| 11 | Unique tool speeds diamond bit drilling 显示文摘 | Association de Recherche Sur Techniques D'exploitation Du Petrol (ARTEP) | 1978 | World Oil1978，187，5： | 1 |
| 12 | Does upper airway muscle injury trigger a vicious cycle in obstructive sleep apnea? A hypothesis显示文摘 | Petrol BJ Hendricks JC Pack AI | 1996 | Sleep1996，19，6： | 1 |
| 13 | A model approach to assess diaphragmatic volume displacement显示文摘 | Petroll WM Knight H Rochester DF | 1990 | JAppl Physiol1990，69，6： | 1 |
| 14 | An experimental model for assessing fibroblast migration in 3-D collagen matrices显示文摘 | Karamichos D Lakshman N Petroll WM | | 0，，： | 1 |
| 15 | Role of surgery in the treatment of primary pulmonah'y B-cell lymphoma显示文摘 | Frederic V Fadel E de Petrol M el al | 2007 | Ann Thorac Surg2007，83，1： | 1 |
| 16 | Ventilator-induced diaphragmatic dysfunction 显示文摘 | Vassilakopoulos T Petrol BJ | 2004 | Am J Respir Crit Care Med2004，169，3： | 1 |
| 17 | Effect of myopic LASIK on corneal sensitivity and morphology of subbasal nerves显示文摘 | Linna TU Vesaluoma MH Pérez-Santonja JJ Petroll WM Alió JL Tervo TM | | 0，，02： | 1 |
| 18 | Stromal wound healing explains refractive instability and haze develop- ment after photorefractive keratectomy: a 1-year confocal mi- croscopic study 显示文摘 | Moller-Pedersen T Cavanagh HD Petroll WM Jester JV | 2000 | Ophthalmology2000，107，7： | 1 |
| 19 | Quantitative assessment ofanteroposterior keratocyte density in the normal rabbit comea显示文摘 | Boettcher K Barry P | 1995 | Cornea1995，14，1： | 1 |
| 20 | Exertion of tractional force requires the coordinated up-regulation of cell contractility and adhension显示文摘 | Roy P Petroll WM Cavanagh HD Jester JV | 1999 | Cell Motil Cytoskeleton1999，43，： | 1 |
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