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| 1 | Gasdermin D is an executor of pyroptosis and required for interleukin-lp secretion显示文摘 | Wan-ting He Haoqiang Wan Lichen Hu Pengda Chen Xin Wang Zhe Huang Zhang-Hua Yang Chuan-Qi Zhong Jiahuai Han | 2015 | Cell Research2015，25，12： | 195 |
| 2 | Sodium Tanshinone Ⅱ A sulfonate for acute myocardial infarction:a systematic review and Meta-analysis显示文摘OBJECTIVE: To investigate the efficacy and safety of Sodium tanshinone ⅡA sulfonate(STS) plus the conventional treatment on acute myocardial infarction(AMI) patients.METHODS: We searched several electrical databases and hand searched several Chinese medical journals up to January 2019. Randomized controlled trials(RCTs) comparing STS plus conventional treatment with conventional treatment were retrieved.Study screening, data extraction, quality assessment, and data analysis were conducted in accordance with the Cochrane standards.RESULTS: Sixteen trials involving 1383 people were included. The Meta-analysis showed STS combined with conventional treatment was a better treatment option than conventional treatment alone in reducing the risk of mortality, heart failure, arrhythmia and shock. In addition, STS was associated with improvement in left ventricular ejection fraction(LVEF) and left ventricular end diastolic dimension(LVEDD). No significant difference of STS was found on recurrent angina and recurrent AMI. However,the safety of STS remained uncertain for limited data.CONCLUSION: Compared with conventional treatment alone, STS combined with conventional treatment may provide more benefits for patients with AMI. Due to the fact that the overall quality of all included trials is generally low, further large-scale high quality trials are warranted. | LIAN Baotao ZENG Ruixiang LIAO Pengda GUO Liheng ZHANG Minzhou CHEN Yuanfang | 2021 | Journal of Traditional Chinese Medicine2021，41，1： | 4 |
| 3 | Theory of Geological Anomaly in Remote Sensing显示文摘Geological anomaly is geological body or complex body with obviously different compositions, structures or orders of genesis as compared with those in the surrounding areas. Geological anomaly, restrained by the geological factors closely associated with ore forming process, is an important clue to ore deposits. The geological anomaly serves as a geological sign to locate ore deposits. Therefore, it is very important to study how to define the characteristics of geological anomaly and further to locate the changes in these characteristics. In this paper, the authors propose the geological anomaly based on the remote sensing images and data, and expound systematically such image features as scale, size, boundary, morphology and genesis of geological anomalies. Then the authors introduce the categorization of the geological anomalies according to their geneses. The image characteristics of some types of geological anomalies, such as the underground geological anomaly, are also explained in detail. Based on the remote sensing interpretation of these geological anomalies, the authors conclude that the forecasting and exploration of ore deposits should be focused on the following three aspects: (1) the analysis of geological setting and geological anomaly; (2) the analysis of circular geological anomaly, and (3) the comprehensive forecasting of ore deposits and the research into multi source information. | Chen Jianping Zhao Pengda Ding Huoping The Institute of High and New Techniques Applied to Land Resources, China University of Geosciences, Beijing 100083 | 2001 | Journal of China University of Geosciences2001，12，2： | 3 |
| 4 | Application of BEMD in Extraction of Magnetic Anomaly Components Associated with Sn-W Polymetallic Mineralization in SE Yunnan,SW China显示文摘The tin(Sn)-tungsten(W)polymetallic ore concentrated district in SE Yunnan is distributed at the junction region of the Yangtze Block,the Cathaysian Block and the Indosinian Block,where there are several giant deposits of tin,tungsten,copper,silver,lead,zinc and indium closely associated with a large scale Late Cretaceous magmatism.Bi-dimensional empirical mode decomposition(BEMD)is used to extract aeromagnetic anomalous components at the survey scale of 1:200000 from the original aeromagnetic data of SE Yunnan.Four intrinsic mode functions(IMFs)and a residues component are obtained,which may reflect the geological structures and geological bodies at different spatial scales from high frequency to low frequency.The results are shown as follows:(1)Two different types of Precambrian basement in the study area were recognized:one is the Yangtze Block basement characterized by a strong positive magnetic anomaly,the other is the Cathaysian Block basement with a weak negative magnetic anomaly.The former consists of high grade metamorphic rocks including metamorphosed basic igneous rocks,while the latter consists of low grade metamorphosed sedimentary rocks.(2)The aeromagnetic anomalies associated with Sn-W polymetallic mineralization and related to granites in the study area illustrate a pattern of a skarnized alteration-mineralization zone with a positive ring magnetic anomaly enclosing a granitic intrusion with negative magnetic anomaly;(3)The ring positive magnetic anomaly zones enclosing the negative magnetic anomaly are defined as the SnW polymetallic ore-searching targets in the study area. | Chen Chen Xu Zhu Yongqing Chen Shouting Zhang Pengda Zhao | 2021 | Journal of Earth Science2021，32，2： | 2 |
| 5 | Anisotropy of Fatigue Behavior and Tensile Behavior of 5A06 Aluminum Alloy Based on Infrared Thermography显示文摘The fatigue behavior during high cycle fatigue testing and the tensile behavior of 5A06 aluminum alloy considering the anisotropy were studied.Two types of specimens including longitudinal specimen(parallel to the rolling direction) and transverse specimen(perpendicular to the rolling direction) were prepared.Infrared thermography was employed to monitor the temperature evolution during the fatigue and tensile tests.The temperature evolution curves in the two directions were contrastively analyzed.It is found that the temperature evolution during fatigue process possesses four stages:initial temperature rise stage,slow temperature decline stage,rapid temperature rise stage,and finial temperature decline stage.The heat generating mechanisms of the four stages are discussed.Obvious differences can be found between the longitudinal specimen and transverse specimen in fatigue strength and fatigue life.The fatigue strength and fatigue life of longitudinal specimen are higher than those of transverse specimen.During the tensile and fatigue testing process,the fracture temperature in the transverse direction are higher than that in the longitudinal direction.The fatigue strength prediction by means of infrared thermography has a good consistency with that by the traditional method. | 闫志峰 张红霞 CHEN Pengda WANG Wenxian | 2017 | Journal of Wuhan University of Technology(Materials Science)2017，32，1： | 1 |
| 6 | 15 K two-stage Stirling-type pulse-tube cryocooler 显示文摘 | Yan Pengda Chen Guobang Dong Jingjing | 2009 | Cryogenics2009，49，2： | 1 |
| 7 | Application of the geo-anomaly unit concept in quantitative delineation and assessment of gold ore targets in western Shandong uplift terrain, Eastern China 显示文摘 | Chen Yongqing Zhao Pengda | 2001 | Natural Resources Research2001，10，1： | 1 |
| 8 | Experimental Study on a Double-orifice Two-Stage Pulse Tube Refrigerator 显示文摘 | CHEN Guobang QIU Limin YAN Pengda | 1997 | Cryogenics1997，37，5： | 1 |
| 9 | Microstructure and Mechanical Properties of Selective Laser Melted Al–2.51Mn–2.71Mg–0.55Sc–0.29Cu–0.31Zn Alloy Designed by Supersaturated Solid Solution显示文摘Selective laser melting(SLM)of aluminium alloys for lightweight application is arousing widespread interest,but the available alloy compositions are limited due to unsatisfactory mechanical performances.The rapid solidifi cation of SLM provides a pathway to design a novel alloy composition with extended solubility.This strategy is demonstrated by an additively manufactured novel Al–2.51 Mn–2.71 Mg–0.55 Sc–0.29 Cu–0.31 Zn alloy with the supersaturated solid solution in the present study.The microstructure of as-build sample is characterized with multi-modal grains with the fi ne equiaxed grain(FEG,~800 nm)at molten pool boundaries,coarse equiaxed grain(CEG,~2μm)and columnar dendrites(CD,~4μm)inside the molten pool,which relates to the precipitations type and distribution.It is observable that Al 3(Sc,Zr)precipitation particles with the size of~50 nm are dispersed in the FEG zone,while the interior of CEG shows no Al3(Sc,Zr)particle which only exists at the CEG boundaries.Regardless of FEG,CEG or CD,the slender Al6 Mn precipitation with the length of~500 nm is distributed along the grain boundaries.Meanwhile,a lot of vacancies and thickness fringes are detected in the FEG zone,which confi rms the supersaturated solid solution in laser rapid solidifi cation.The ultimate tensile strength and yield strength of the as-printed sample are~380 MPa and~330 MPa,respectively,with elongation~14%,which increase to~440 MPa and~410 MPa with a reduction of elongation to~9%after heat treatment. | Minbo Wang Ruidi Li Tiechui Yuan Haiou Yang Pengda Niu Chao Chen | 2022 | Acta Metallurgica Sinica(English Letters)2022，35，3： | 1 |
| 10 | Digital Geosciences and Quantitative Mineral Exploration显示文摘The idea of mineral exploration,which is called'exploration philosophy'in the Western countries,is the thoughts,the methodology,technology,goals and organization that guide mineral exploration.The three basic elements of mineral exploration are'what to find','where to find'and'how to find'.The concept of mineral exploration is gradually changing with the development of these three elements that provide a powerful driving force to change mineral exploration concepts,methods and technology.Innovation of mineral exploration concepts is the result of continuing exploration and development keeping pace with the times.The combination of'mathematical geology'and'information technology'can be called'digital geology'.Digital geology is the data analysis component of geological science.Geological data science is a science that uses the general methodology of data to study geology based on the characteristics of geological data and the needs of geological field work.Digital mineral exploration is the application of digital geology in mineral exploration to reduce ore-finding uncertainty. | Pengda Zhao Yongqing Chen | 2021 | Journal of Earth Science2021，32，2： | 1 |
| 11 | 15<ce:hsp sp='0.25'/>K two-stage Stirling-type pulse-tube cryocooler显示文摘 | Pengda Yan Guobang Chen Jingjing Dong Weili Gao | 2008 | Cryogenics2008，，2： | 1 |
| 12 | The 'Three-Component' digital prospecting method:A new approach for mineral resource quantitative prediction and assessment显示文摘 | Zhao Pengda Chen Jianping Chen Jianguo | 2005 | Natural Resources Research2005，14，4： | 1 |
| 13 | Zonation in primary halos and geochemical prospecting pattern for the Guilaizhuang gold deposit, eastern China显示文摘 | Chen Yongqing Zhao Pengda | 1998 | Nonrenewable Resources1998，，1： | 1 |
| 14 | Application of The Geo-anomaly Unit Concept in Quantitative Delineation and Assessment of Gold Ore Targets In Western Shandong Uplift Terrain, Eastern China显示文摘 | Pengda Zhao Jianguo Chen Jiping Liu | 2001 | Natural Resources Research2001，10，1： | 1 |
| 15 | Discussion on Nontraditional Mineral Resources显示文摘In this paper, the authors introduce the concept of nontraditional mineral resources, and propose the major system of nontraditional mineral resources, including nontraditional resources, research methods, mining and mineral economics. Then the authors conclude that the research on nontraditional mineral resources is not only significant to satisfication the human needs in the 21st century, but also important to the development of the present geological theory. | Zhao Pengda Chen Jianping China University of Geosciences, Beijing 100083, China | 2000 | Journal of Earth Science2000，19，3： | 0 |
| 16 | Important Issues of Sustainable Development:Research of Nontraditional Mineral Resources显示文摘Nontraditional resources refer to that potential mineral resources are unconsidered and unutilized under actual condition of technique, economic and environment, or some mineral resources are too difficult to find because of geological complexity. There are some signified problems about discovery and exploration of nontraditional mineral resources to be discussed in this paper. It is a very significant project next century, and makes development bases for offspring, which its research and practice the theory of nontraditional mineral resources need interactive combination. | Zhao Pengda Chen Jianping Institute of High and New Techniques Applied to Land Resources, China University of Geosciences, Beijing 100083 | 2000 | Journal of Earth Science2000，19，2： | 0 |
| 17 | Dhx33 promotes B-cell growth and proliferation by controlling activation-induced rRNA upregulation显示文摘Upon recognition of foreign antigens,naïve B cells undergo rapid activation,growth,and proliferation.How B-cell growth and proliferation are coupled with activation remains poorly understood.Combining CRISPR/Cas9-mediated functional analysis and mouse genetics approaches,we found that Dhx33,an activation-induced RNA helicase,plays a critical role in coupling B-cell activation with growth and proliferation.Mutant mice with B-cell-specific deletion of Dhx33 exhibited impaired B-cell development,germinal center reactions,plasma cell differentiation,and antibody production.Dhx33-deficient B cells appeared normal in the steady state and early stage of activation but were retarded in growth and proliferation.Mechanistically,Dhx33 played an indispensable role in activation-induced upregulation of ribosomal DNA(rDNA)transcription.In the absence of Dhx33,activated B cells were compromised in their ability to ramp up 47S ribosomal RNA(rRNA)production and ribosome biogenesis,resulting in nucleolar stress,p53 accumulation,and cellular death.Our findings demonstrate an essential role for Dhx33 in coupling B-cell activation with growth and proliferation and suggest that Dhx33 inhibition is a potential therapy for lymphoma and antibody-mediated autoimmune diseases. | Xiaoyu He Jiayi Zhao Abidan Adilijiang Peicheng Hong Pengda Chen Xinyong Lin Jun Xie Ying Du Yun Liu Lianghua Lin Hyun Yong Jin Yazhen Hong Wen-Hsien Liu Changchun Xiao | 2023 | Cellular & Molecular Immunology2023，20，3： | 0 |
| 18 | Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses显示文摘Dear Editor,The recent health emergency caused by SARS-CoV-2 created a global pandemic.Similar to other CoVs,SARS-CoV-2 utilizes its Spike(S)protein to specifically recognize the human angiotensin converting enzyme 2(ACE2)membrane receptor for infection. | Siyuan Su Jianfeng Chen Ying Wang Lilly M.Wong Zhichuan Zhu Guochun Jiang Pengda Liu | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 0 |
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