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| 1 | Gasdermin D is an executor of pyroptosis and required for interleukin-lp secretion显示文摘 | Wan-ting He Haoqiang Wan Lichen Hu Pengda Chen Xin Wang Zhe Huang Zhang-Hua Yang Chuan-Qi Zhong Jiahuai Han | 2015 | Cell Research2015，25，12： | 195 |
| 2 | MYB Transcription Factors as Regulators of Phenylpropanoid Metabolism in Plants显示文摘导出 Phenylpropanoid 的混合物代表从本氨基丙酸发源的第二等的代谢物的一个多样的家庭。这些混合物对关於生命、不能生活的应力在植物生长和开发,并且在防卫有角色。许多这些混合物对人的健康和福利也有益。V-myb myeloblastosis 病毒的 oncogene 相当或相同的事物(MYB ) 蛋白质属于抄写因素的一个大家庭并且是导出 phenylpropanoid 的混合物的合成的关键管理者。这评论在植物在 phenylpropanoid 新陈代谢的规定总结 MYB 蛋白质和他们的角色的当前的理解。 | Jingying Liu Anne Osbourm Pengda Ma | 2015 | Molecular Plant2015，8，5： | 79 |
| 3 | Singularity theories and methods for characterizing mineralization processes and mapping geo-anomalies for mineral deposit prediction显示文摘在这份报纸,我们证明 geo 异例能根据理论开发了描绘非线性的矿化作用过程的奇特为矿物沉积物预言被描出。联系奇特和 geo 异例与现代非线性的理论和方法使它可能到份量上学习 geo 异例。这份报纸为为矿物沉积物预言描绘并且印射 geo 异例介绍非线性的矿化作用过程和非线性的方法的最新发达的奇特分析。作为 geo 异例引起的单个矿化作用过程的产品,矿藏能借助于分数维图形或 multifractal 模型被描绘。奇特能描绘 geo 反常的度,这被显示出,并且这被表明了为印射未被发现的矿藏的异例有用。从一个非线性的过程观点的矿化作用和矿藏的学习是一个新却有希望的研究方向。这研究强调在 geo 异例和奇特之间的关系,包括导致奇特和 geo 异例的单个过程,奇特和 geo 异例和为矿物沉积物预言的 geo 异例的鉴定的描述。这些概念和方法在云南在 Gejiu 矿物质区域用 Sn 矿物沉积物预言的案例研究被表明,中国。 | Qiuming Cheng Pengda Zhao | 2011 | Geoscience Frontiers2011，2，1： | 9 |
| 4 | Effects of sediment physical properties on the phosphorus release in aquatic environment显示文摘Particle size, porosity, and the initial phosphorus concentration in sediments are the main factors affecting phosphorus release flux through the sediment-water interface. Sediments can be physically divided to muddy and sandy matters, and the adsorption-desorption capacity of sediment with phosphorus depends on particle size. According to phosphorus adsorption-desorption experiments, phosphorus sorption capacity of the sediment decreases with the increase of particle dimension. But among the size-similar particles, sediment with a bigger particle size has the larger initial phosphorus release rate. In terms of muddy and sandy sediments, there are inversely proportional relationships between the release rate and the flux. Due to the contact of surface sediment and the overlying water, the release flux from the sediment is either from direct desorption of surface sediment layer or from the diffusion of pore water in the sediment layer, which is mainly determined by sediment particle size and porosity. Generally, static phosphorus release process may include two stages: the first is the initial release. As for coarse particles, phosphorus is desorbed from surface sediment. And for fine particles, phosphorus concentration in water often decreases, mainly from pore water by the molecular diffusion. During the second stage, pore water flows faster in coarse sediment, and phosphorus is easy to desorb from the surface of the particles as diffusion dominates. For the smaller liquid-solid ratio of fine particles and the larger amount of phosphorus adsorption, the release flux from pore water due to diffusion is very small with longer sorption duration. | ZHU HongWei WANG DaoZeng CHENG PengDa FAN JingYu ZHONG BaoChang | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，2： | 8 |
| 5 | Character of the Si and Al Phases in Coal Gangue and Its Ash显示文摘Analysis of the Si and Al phases in coal gangue fuel and its ash is important for use of coal gangue ashes. A comprehensive study by theoretical and experimental analyses with differential thermal analysis, X-ray diffraction and Infrared Spectroscopy has been made in the present article to explore the diagram of the Si and Al phases in coal gangue fuel and its ashes. It is found that kaolinite and quartz are the main phases in coal gangue fuel. The ratio of moles Al2O3 to SiO2 (i.e., Al2O3 (mole)/SiO2 (mole)) is usually no more than 0.5 in most coal gangue fuel and its ashes. The kaolinit at about 984°C releases a large quantity of SiO2, which makes calcine coal gangue more active than coal gangue itself. The relationship between the ratio Al2O3 (mole)/SiO2(mole) and the components of coal gangue ash is analyzed, resulting in a formula to calculate the quantity of each phase. Applying the formula to the testing samples from an electric plant in north China supports the above conclusions. | WANG Lihua ZHAO Pengda LI Geng | 2009 | Acta Geologica Sinica(English Edition)2009，83，6： | 6 |
| 6 | The mechanisms of contaminants release due to incipient motion at sediment-water interface显示文摘Sediments in many rivers and lakes are subjected to resuspension due to a combination of hydrodynamics.However,the roles of contaminant-contained dissolved and particulate sediments during the resuspension release are rarely studied.This study focuses on the release quantity of contaminants in both water phase and solid phase.Conservative tracer(NaCl)and reactive tracer(Phosphorus)were respectively added to cohesive fine-grained sediments and non-cohesive coarse-grained sediments.A range of typical shear stress was conducted to characterize the time-depended release of contaminants in a laboratory flume.When the sediment started to move,the concentration of contaminant in the overlying water increased with the bed shear stress,but the dissolved contaminants responded faster than the particulate ones.The observed contaminant release process can be divided into three main stages:the initial two hours fast mixing:the release contribution of pore water could reach up to 75%;the middle 4–6 h adsorption:the partitioning coefficient of contaminant between water phase and solid phase decreased over the time,and the adsorption of contaminates from resuspended sediment dominated the negative release;the last equilibrium stage:the desorption and adsorption reached equilibrium,and the reactive contaminant made an impact on the water quality in the solid phase.The existing formulas to evaluate the release flux are far from practice meaning as the sediment contaminants undergo a very complex release process. | ZHU HongWei CHENG PengDa ZHONG BaoChang WANG DaoZeng | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 4 |
| 7 | A Fluorescent Zirconium-Based Metal-Organic Framework for Selective Detection of Nitro Explosives and Metal Ions显示文摘 | YuanzheTang Hongliang Huang Yaguang Peng Qunqun Ruan KekeWang Pengda Yi Dahuan Liu Chongli Zhong | 2017 | Chinese Journal of Chemistry2017，35，7： | 4 |
| 8 | Sodium Tanshinone Ⅱ A sulfonate for acute myocardial infarction:a systematic review and Meta-analysis显示文摘OBJECTIVE: To investigate the efficacy and safety of Sodium tanshinone ⅡA sulfonate(STS) plus the conventional treatment on acute myocardial infarction(AMI) patients.METHODS: We searched several electrical databases and hand searched several Chinese medical journals up to January 2019. Randomized controlled trials(RCTs) comparing STS plus conventional treatment with conventional treatment were retrieved.Study screening, data extraction, quality assessment, and data analysis were conducted in accordance with the Cochrane standards.RESULTS: Sixteen trials involving 1383 people were included. The Meta-analysis showed STS combined with conventional treatment was a better treatment option than conventional treatment alone in reducing the risk of mortality, heart failure, arrhythmia and shock. In addition, STS was associated with improvement in left ventricular ejection fraction(LVEF) and left ventricular end diastolic dimension(LVEDD). No significant difference of STS was found on recurrent angina and recurrent AMI. However,the safety of STS remained uncertain for limited data.CONCLUSION: Compared with conventional treatment alone, STS combined with conventional treatment may provide more benefits for patients with AMI. Due to the fact that the overall quality of all included trials is generally low, further large-scale high quality trials are warranted. | LIAN Baotao ZENG Ruixiang LIAO Pengda GUO Liheng ZHANG Minzhou CHEN Yuanfang | 2021 | Journal of Traditional Chinese Medicine2021，41，1： | 4 |
| 9 | Low-overpotential selective reduction of CO2 to ethanol on electrodeposited CuxAuy nanowire arrays显示文摘Direct electrochemical reduction of CO2 to multicarbon products is highly desirable, yet challenging. Here, we present a potentiostatic pulse-electrodeposition of high-aspect-ratio CuxAuy nanowire arrays (NWAs) as high-performance electrocatalysts for the CO2 reduction reaction (CO2RR). The surface electronic structure related to the Cu:Au ratio in the CuxAuy NWAs could be facilely modulated by controlling the electrodeposition potential and the as-fabricated CuxAuy NWAs could be directly used as the catalytic electrode for the CO2RR. The morphology of the high-aspect-ratio nanowire array significantly lowers the onset potential of the alcohol formation due to the diffusion-induced enhancement of the local pH and CO concentration near the nanowire surface. Besides, the properly adjusted surface electronic structure of the CuxAuy NWA enables the adsorption of CO and facilitates the subsequent CO reduction to ethanol via the C-C coupling pathway. Owing to the synergistic effect of morphology and electronic structure, the optimized CuxAuy NWA selectively reduces CO2 to ethanol at low potentials of -0.5——0.7 V vs. RHE with a highest Faradaic efficiency of 48%. This work demonstrates the feasibility to optimize the activity and selectivity of the Cu-based electrocatalysts toward multicarbon alcohols for the CO2RR via simultaneous adjustment of the electronic structure and morphology of the catalysts. | Weiwei Zhu Kuangmin Zhao Suqin Liu Min Liu Feng Peng Pengda An Binhao Qin Huimin Zhou Hongmei Li Zhen He | 2019 | Journal of Energy Chemistry2019，28，10： | 4 |
| 10 | Geological Anomaly of China显示文摘Geological Anomaly of China￥ZhaoPengda(FacultyofEarthResources,ChinaUniversityofGeosciences,Wuhan430074)WangJinggui;RaoMinghu... | Zhao Pengda(Faculty of Earth Resources,China University of Geosciences, Wuhan 430074)Wang Jinggui Rao Minghui Li Haochang(Department of Geology, East China College of Geology, Fuzhou 344000) | 1995 | Journal of Earth Science1995，14，1： | 3 |
| 11 | Numerical simulation of phosphorus release from resuspended sediment显示文摘One of the main issues in environmental hydraulics is pollutant release from sediments.For instance,the strong affinity between phosphorus and sediment permits most of the phosphorus to be adsorbed on the surface of the sediment particles in rivers or lakes.Post sediment resuspension,phosphorus is desorbed from the sediment to the overlying water.The release of phosphorus from the resuspended sediment is an important process in the secondary pollution of water.Herein,a coupled mechanical model of the overlying water,sediment,and pollutant was established based on the experimentally gathered data.Two types of sediment with different adsorption and desorption characteristics were selected to simulate the process of sediment resuspension and phosphorus release under different hydrodynamic conditions.The simulation results were subsequently used to analyze the relationship between the flow field characteristics and phosphorus concentration,from which the relationships between velocity,particle volume fraction,turbulent kinetic energy,total phosphorus concentration,desorbed phosphorus concentration,and time were elucidated.Based on the results,phosphorus is rapidly released into the overlying water from the resuspended sediment,and it reaches a peak value in a short duration.Unlike the release process of non-adsorption pollutants,hydrodynamic conditions and sediment properties play a crucial role in the phosphorus release process.The turbulent kinetic energy rapidly increases with the flow velocity,whereas the desorbed phosphorus concentration exhibits a certain relationship with the particle volume fraction and turbulent kinetic energy.In particular,the turbulent kinetic energy increases the desorbed phosphorus concentration per unit time.Additionally,the time taken by the total phosphorus concentration to attain its peak value is closely related to the characteristics of the flow field,whereas the amount of phosphorus is closely related to sediment properties.Post sediment resuspension,the release of phosphorus shows the characteristics of a centralized and massive release,which suggests that the total phosphorus concentration in the overlying water would change in a short duration and cause secondary pollution in the water environment. | Pengda Cheng Xinquan Wang Chun Feng | 2020 | Acta Mechanica Sinica2020，36，6： | 3 |
| 12 | Theory of Geological Anomaly in Remote Sensing显示文摘Geological anomaly is geological body or complex body with obviously different compositions, structures or orders of genesis as compared with those in the surrounding areas. Geological anomaly, restrained by the geological factors closely associated with ore forming process, is an important clue to ore deposits. The geological anomaly serves as a geological sign to locate ore deposits. Therefore, it is very important to study how to define the characteristics of geological anomaly and further to locate the changes in these characteristics. In this paper, the authors propose the geological anomaly based on the remote sensing images and data, and expound systematically such image features as scale, size, boundary, morphology and genesis of geological anomalies. Then the authors introduce the categorization of the geological anomalies according to their geneses. The image characteristics of some types of geological anomalies, such as the underground geological anomaly, are also explained in detail. Based on the remote sensing interpretation of these geological anomalies, the authors conclude that the forecasting and exploration of ore deposits should be focused on the following three aspects: (1) the analysis of geological setting and geological anomaly; (2) the analysis of circular geological anomaly, and (3) the comprehensive forecasting of ore deposits and the research into multi source information. | Chen Jianping Zhao Pengda Ding Huoping The Institute of High and New Techniques Applied to Land Resources, China University of Geosciences, Beijing 100083 | 2001 | Journal of China University of Geosciences2001，12，2： | 3 |
| 13 | Transport mechanisms of contaminants released from fine sediment in rivers显示文摘Contaminants released from sediment into rivers are one of the main problems to study in environmental hydrodynamics. For contaminants released into the overlying water under different hydrodynamic conditions, the mechanical mechanisms involved can be roughly divided into convective diffusion, molecular diffusion, and adsorption/desorption. Because of the obvious environmental influence of fine sediment( D90 = 0.06 mm), non-cohesive fine sediment, and cohesive fine sediment are researched in this paper, and phosphorus is chosen for a typical adsorption of a contaminant. Through theoretical analysis of the contaminant release process, according to different hydraulic conditions, the contaminant release coupling mathematical model can be established by the N–S equation, the Darcy equation,the solute transport equation, and the adsorption/desorption equation. Then, the experiments are completed in an open water flume. The simulation results and experimental results show that convective diffusion dominates the contaminant release both in non-cohesive and cohesive fine sediment after their suspension, and that they contribute more than 90 % of the total release. Molecular diffusion and desorption have more of a contribution for contaminant release from unsuspended sediment. In unsuspension sediment, convective diffusion is about 10–50 times larger than molecular diffusion during the initial stages under high velocity; it is close to molecular diffusion in the later stages. Convective diffusion is about 6 times larger than molecular diffusion during theinitial stages under low velocity, it is about a quarter of molecular diffusion in later stages, and has a similar level with desorption/adsorption. In unsuspended sediment, a seepage boundary layer exists below the water–sediment interface,and various release mechanisms in that layer mostly dominate the contaminant release process. In non-cohesive fine sediment, the depth of that layer increases linearly with shear stress. In cohesive fine sediment, the range seepage boundary is different from that in non-cohesive sediment, and that phenomenon is more obvious under a lower shear stress. | Pengda Cheng Hongwei Zhu Baochang Zhong Daozeng Wang | 2015 | Acta Mechanica Sinica2015，31，6： | 3 |
| 14 | The SmMYB36-SmERF6/SmERF115 module regulates the biosynthesis of tanshinones and phenolic acids in salvia miltiorrhiza hairy roots显示文摘Tanshinone and phenolic acids are the most important active substances of Salvia miltiorrhiza,and the insight into their transcriptional regulatory mechanisms is an essential process to increase their content in vivo.SmMYB36 has been found to have important regulatory functions in the synthesis of tanshinone and phenolic acid;paradoxically,its mechanism of action in S.miltiorrhiza is not clear.Here,we demonstrated that SmMYB36 functions as a promoter of tanshinones accumulation and a suppressor of phenolic acids through the generation of SmMYB36 overexpressed and chimeric SmMYB36-SRDX(EAR repressive domain)repressor hairy roots in combination with transcriptomic-metabolomic analysis.SmMYB36 directly down-regulate the key enzyme gene of primary metabolism,SmGAPC,up-regulate the tanshinones biosynthesis branch genes SmDXS2,SmGGPPS1,SmCPS1 and down-regulate the phenolic acids biosynthesis branch enzyme gene,SmRAS.Meanwhile,SmERF6,a positive regulator of tanshinone synthesis activating SmCPS1,was up-regulated and SmERF115,a positive regulator of phenolic acid biosynthesis activating SmRAS,was down-regulated.Furthermore,the seven acidic amino acids at the C-terminus of SmMYB36 are required for both self-activating domain and activation of target gene expression.As a consequence,this study contributes to reveal the potential relevance of transcription factors synergistically regulating the biosynthesis of tanshinone and phenolic acid. | Qi Li Xin Fang Ying Zhao Ruizhi Cao Juane Dong Pengda Ma | 2023 | Horticulture Research2023，10，1： | 2 |
| 15 | Application of GISto Geo-anomaly-Based Delineation of Mineral Resources显示文摘In this paper, the Dongchuan type copper deposits are taken as an example to illustrate the application of GIS to the geo anomaly based delineation of mineral resources. The following eight steps are listed in this paper to delineate the permissive and preferable ore finding areas: (1) the analysis of favorable prospecting index using linear and planar geo anomalies; (2) the analysis of favorable prospecting index using combined anomalies; (3) the construction of a GIS based spatial model for mineral prognosis; (4) the delineation of the permissive ore finding area; (5) the determination of the synthetic anomalies and numerical range for the prediction of the favorable prospecting areas, and the determination of the weights of these two variables; (6) the superimposition of all the selected anomalies and the construction of the superimposition map; (7) the determination of unifying criterion of favorable prospective areas at various levels, and (8) the delineation of favorable prospective areas. Finally, this paper offers a detailed discussion of the results in the forecasting of Dongchuan type copper deposits. | Chi Shundu Zhao Pengda Li Jianwei The Open Laboratory of Quantitative Prediction and Exploration Assessment of Mineral Resources, Ministry of Land and Resources, Wuhan 430074 | 2000 | Journal of Earth Science2000，19，2： | 2 |
| 16 | Application of BEMD in Extraction of Magnetic Anomaly Components Associated with Sn-W Polymetallic Mineralization in SE Yunnan,SW China显示文摘The tin(Sn)-tungsten(W)polymetallic ore concentrated district in SE Yunnan is distributed at the junction region of the Yangtze Block,the Cathaysian Block and the Indosinian Block,where there are several giant deposits of tin,tungsten,copper,silver,lead,zinc and indium closely associated with a large scale Late Cretaceous magmatism.Bi-dimensional empirical mode decomposition(BEMD)is used to extract aeromagnetic anomalous components at the survey scale of 1:200000 from the original aeromagnetic data of SE Yunnan.Four intrinsic mode functions(IMFs)and a residues component are obtained,which may reflect the geological structures and geological bodies at different spatial scales from high frequency to low frequency.The results are shown as follows:(1)Two different types of Precambrian basement in the study area were recognized:one is the Yangtze Block basement characterized by a strong positive magnetic anomaly,the other is the Cathaysian Block basement with a weak negative magnetic anomaly.The former consists of high grade metamorphic rocks including metamorphosed basic igneous rocks,while the latter consists of low grade metamorphosed sedimentary rocks.(2)The aeromagnetic anomalies associated with Sn-W polymetallic mineralization and related to granites in the study area illustrate a pattern of a skarnized alteration-mineralization zone with a positive ring magnetic anomaly enclosing a granitic intrusion with negative magnetic anomaly;(3)The ring positive magnetic anomaly zones enclosing the negative magnetic anomaly are defined as the SnW polymetallic ore-searching targets in the study area. | Chen Chen Xu Zhu Yongqing Chen Shouting Zhang Pengda Zhao | 2021 | Journal of Earth Science2021，32，2： | 2 |
| 17 | Theoretical study of statistical fractal model with applications to mineral resource prediction 显示文摘 | SHEN Wei ZHAO Pengda | 2002 | Computers Geoscienees2002，28，： | 1 |
| 18 | Expression of human acidic fibroblast growth factor in nicotiana ben- thaminana with a potato-virus-X-based binary vector 显示文摘 | JINGYING L PENGDA M MEIYING Y | 2007 | Biotechnol Appl Bionchem2007，48，3： | 1 |
| 19 | Theories, Principles, and methods for statisti cal prediction of mineral deposits显示文摘 | Zhao Pengda | 1992 | Mathematical Geology1992，，6： | 1 |
| 20 | Cytosolic DNA sensing by cGAS:regulation,function,and human diseases显示文摘Sensing invasive cytosolic DNA is an integral component of innate immunity.cGAS was identified in 2013 as the major cytosolic DNA sensor that binds dsDNA to catalyze the synthesis of a special asymmetric cyclic-dinucleotide,2/3/-cGAMP,as the secondary messenger to bind and activate STING for subsequent production of type I interferons and other immune-modulatory genes.Hyperactivation of cGAS signaling contributes to autoimmune diseases but serves as an adjuvant for anticancer immune therapy.On the other hand,inactivation of cGAS signaling causes deficiency to sense and clear the viral and bacterial infection and creates a tumor-prone immune microenvironment to facilitate tumor evasion of immune surveillance.Thus,cGAS activation is tightly controlled.In this review,we summarize up-to-date multilayers of regulatory mechanisms governing cGAS activation,including cGAS pre-and post-translational regulations,cGAS-binding proteins,and additional cGAS regulators such as ions and small molecules.We will also reveal the pathophysiological function of cGAS and its product cGAMP in human diseases.We hope to provide an up-to-date review for recent research advances of cGAS biology and cGAS-targeted therapies for human diseases. | Le Yu Pengda Liu | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 1 |
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