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| 1 | Current cancer burden in China: epidemiology, etiology, and prevention显示文摘Cancer has become the most common cause of death in China.Owing to rapid economic development,improved livelihood,and shifts in risk factors,cancer epidemiology has experienced substantial changes during the past several decades.In this review,we aim to describe the current cancer epidemiology of the main types of cancer in China,report major risk factors associated with cancer development,and summarize the contributions of the Chinese government to controlling the cancer burden.A total of 4,064,000 new cases were diagnosed in China in 2016.The most frequent types are lung cancer(828,100;20.4%),colorectal cancer(408,000;10.0%),and gastric cancer(396,500;9.8%).Lung(657,000;27.2%),liver(336,400,13.9%),and stomach(288,500;12.0%)cancers are the 3 most deadly cancers in the general population.The 5-year survival rate for cancer has dramatically increased in recent decades.However,liver and particularly pancreatic cancers still have the poorest prognosis.The main modifiable risk factors associated with cancer development include infectious agents,smoking,alcohol consumption,obesity,unhealthful dietary habits,and inadequate physical activity.The Chinese government has made unremitting efforts to decrease the cancer burden,including cancer education and investment in cancer screening programs. | Maomao Cao He Li Dianqin Sun Siyi He Xinxin Yan Fan Yang Shaoli Zhang Changfa Xia Lin Lei Ji Peng Wanqing Chen | 2022 | Cancer Biology & Medicine2022，19，8： | 33 |
| 2 | Analysis of bacterial community in bulking sludge using culture-dependent and -independent approaches显示文摘The bacterial community of a bulking sludge from a municipal wastewater treatment plant with anoxic-anaerobic-oxic process was investigated by combination of cultivation and 16S rRNA gene clone library analysis for understanding the causes of bulking.A total of 28 species were obtained from 63 isolates collected from six culture media.The most cultivable species belonged to γ-Proteobacteria including Klebsiella sp.,Pseudomonas sp.,Aeromonas sp.and Acinetobacter sp.Further analysis of these strains by repetitive sequence based on polymerase chain reaction (rep-PCR) technology showed that rep-PCR yielded discriminatory banding patterns within the same genus using REP and BOX primer sets.While the culture-independent assessment revealed that β-Proteobacteria was the dominant group in the bulking sample.Sequence analysis revealed that the highest proportion (14.7%) of operational taxonomic units was 98% similar to Candidatus Accumulibacter phosphatis,which is used to remove phosphorous from wastewater.Our results indicated that combining different approaches can produce complementary information,thus generate a more accurate view of microbial community in bulking sludge. | Decai Jin Ping Wang Zhihui Bai Xinxin Wang Hong Peng Rong Qi Zhisheng Yu Guoqiang Zhuang | 2011 | Journal of Environmental Sciences2011，23，11： | 11 |
| 3 | Tongluo Digui decoction(通络地龟汤)treats renal injury in diabetic rats by promoting autophagy of podocytes显示文摘OBJECTIVE:To investigate the effects of Tongluo Digui decoction on renal injury and streptozotocin-induced podocyte autophagy in diabetic rats.METHODS:Male Sprague-Dawley rats were randomly divided into six groups:normal,model,Tongluo Digui decoction(high,medium,and low dose)and valsartan.Streptozotocin was injected intraperitoneally to replicate the diabetic animal model.After 8 weeks,proteinuria was evaluated to establish the diabetic nephropathy model.Treatments were administered daily via the intragastric route.At 16 weeks after gavage,we determined 24 h urine protein concentration,and blood glucose,serum creatinine,and urea nitrogen concentrations.Then,rats were sacrificed,and kidneys were harvested and stained with periodic acid-Schiff to evaluate the pathological changes in glomeruli,including glomerular podocytes by transmission electron microscopy.Western blot analysis was used to determine the expression of nephrin,podocin,p62,beclin-1,LC3Ⅱ/Ⅰ,and p-m TOR/m TOR protein in kidney tissues.RESULTS:Compared with the model group,Tongluo Digui decoction was associated with decreases in 24 h urine protein concentration,and blood glucose,hemoglobin A1 c,serum creatinine,urea nitrogen concentrations,total serum protein and albumin.Concurrently,mesangial mesenteric broadening and fusion of foot processes were reduced,the glomerular basement membrane was not significantly thickened,and the number of podocytes and the number of autophagosomes in the podocytes was increased.Further,expression of nephrin,podocin,LC3Ⅱ,and beclin-1 protein in kidney tissue was up-regulated,while expression of p62 protein was down-regulated and m TOR phosphorylation was inhibited.CONCLUSION:Tongluo Digui decoction may inhibit the progression of diabetic nephropathy by inhibiting m TOR phosphorylation,thereby increasing autophagy to protect podocytes and reducing proteinuria. | HAN Jiarui ZHANG Yage SHI Xiujie PENG Zining XING Yufeng PANG Xinxin | 2021 | Journal of Traditional Chinese Medicine2021，41，1： | 9 |
| 4 | Colorectal cancer burden,trends and risk factors in China:A review and comparison with the United States显示文摘Objective:China and the United States(the U.S.)have the heaviest colorectal cancer(CRC)burden with considerable variations in temporal trends.This study aims to analyze the temporal patterns of CRC burden and its risk factors in China and the U.S.across the past three decades.Methods:Data were extracted from the Global Burden of Disease(GBD)Study in 2019,including cases,deaths,disability-adjusted life-years(DALYs),age-standardized rate(ASR),and summary exposure value(SEV)of CRC in China and the U.S.between 1990 and 2019.Annual average percentage changes(AAPCs)of CRC burden were calculated using the Joinpoint regression model.The mortality in CRC attributable to potential risk factors was characterized by countries,gender,and age groups.Results:In 2019,there were 607,900 and 227,241 CRC cases,and 261,777 and 84,026 CRC deaths in China and the U.S.,respectively.The age-standardized incidence rate(ASIR)was 30.55 per 100,000 in China and 41.86 per100,000 in the U.S.,and the age-standardized mortality rate(ASMR)was 13.86 per 100,000 in China and 14.77 per100,000 in the U.S.CRC incidence,mortality,and DALY rate in the U.S.showed downward trends in the past three decades(AAPC=-0.47,-1.06,and-0.88,respectively),while upward trends were observed in China(AAPC=3.11,1.05,and 0.91,respectively).Among the cause of CRC,the leading risk factor contributing to CRC death was low milk in China and smoking in the U.S.,respectively.Conclusions:From 1990 to 2019,the burden of CRC in China increased dramatically,particularly for males and middle-aged and elderly people.The management of the major risk factors associated with the high burden of CRC should be enhanced. | Qianru Li Hongliang Wu Maomao Cao He Li Siyi He Fan Yang Xinxin Yan Shaoli Zhang Yi Teng Changfa Xia Ji Peng Wanqing Chen | 2022 | Chinese Journal of Cancer Research2022，34，5： | 6 |
| 5 | The chromosome-level Hemerocallis citrina Borani genome provides new insights into the rutin biosynthesis and the lack of colchicine显示文摘Hemerocallis citrina Borani(huang hua cai in Chinese)is an important horticultural crop whose flower buds are widely consumed as a delicious vegetable in Asia.Here we assembled a high-quality reference genome of H.citrina using single-molecule sequencing and Hi-C technologies.The genome assembly was 3.77 Gb and consisted of 3183 contigs with a contig N50 of 2.09 Mb,which were further clustered into 11 pseudochromosomes.A larger portion(3.25 Gb or 86.20%)was annotated as a repetitive content and 54,295 protein-coding genes were annotated in the genome.Genome evolution analysis showed that H.citrina experienced a recent whole-genome duplication(WGD)event at~15.73 million years ago(Mya),which was the main factor leading to many multiple copies of orthologous genes.We used this reference genome to predict 20 genes involved in the rutin biosynthesis pathway.Moreover,our metabolomics data revealed neither colchicine nor its precursors in H.citrina,challenging the long-standing belief that this alkaloid causes poisoning by the plant.The results of our disruptive research are further substantiated by our genomic finding that H.citrina does not contain any genes involved in colchicine biosynthesis.The high-quality genome lays a solid foundation for genetic research and molecular breeding of H.citrina. | Zhixing Qing Jinghong Liu Xinxin Yi Xiubin Liu Guoan Hu Jia Lao Wei He Zihui Yang Xiaoyan Zou Mengshan Sun Peng Huang Jianguo Zeng | 2021 | Horticulture Research2021，8，1： | 6 |
| 6 | Covalent organic frameworks derived hollow structured N-doped noble carbon for asymmetric-electrolyte Zn-air battery显示文摘We report a relatively low-temperature molten salt strategy to prepare hollow structured N-doped noble carbon(h-NNC) with highly desirable features of ultra-large surface area(1957 m^2 g^(-1)) and high graphitization, endowing the h-NNC with high activity toward catalysis of oxygen reduction reaction in acidic medium. The h-NNC is applied as cathode catalyst of an asymmetrical-electrolyte Zn-air battery, which exhibits an open circuit voltage of 2.11 V, a power density up to 270 mW cm^(-2),and an energy density of 1279 W h kg^(-1), behaving advantages over the conventional Zn-air batteries. | Pingwei Cai Xinxin Peng Junheng Huang Jingchun Jia Xiang Hu Zhenhai Wen | 2019 | Science China Chemistry2019，62，3： | 6 |
| 7 | Regeneration of Simulated Deactivated Hollow Titanium Silicate Zeolite by Secondary Crystallization in the TPAOH Solution显示文摘It is of paramount importance to improve the utilization efficiency of hollow titanium silicate(HTS) zeolite catalyst used in the cyclohexanone ammoxidation process. To achieve this aim, the regeneration of simulated deactivated HTS zeolite by post-synthesis was carried out in an aqueous TPAOH solution under hydrothermal conditions. It was found that the catalytic performance for phenol hydroxylation over regenerated HTS zeolite was as high as that of fresh one.Judging from the BET measurements, electron micrography and XRD analysis results, it was confirmed that the topological and morphological structure was repaired. The chemical state of Ti species was detected by the UV-Vis and ^(29)Si MAS NMR spectroscopy. No acidic amorphous TiO_2-SiO_2 oxide was formed, and the extraframework Ti species could be reincorporated into the framework of HTS zeolite thanks to the tetrahedral coordination by the condensation between Ti-OH and Si-OH groups. In order to confirm this conclusion, the fresh HTS zeolite was treated under the NH_3·H_2O hydrothermal and thermal conditions for several times. The catalytic activity of both uncalcined and calcined simulated deactivated HTS zeolite samples could be regenerated without the formation of Br?nsted acid sites. It was concluded that the highly dispersed Ti species could be reincorporated into the framework of zeolite by hydrated condensation of Si-OH and Ti-OH groups after secondary hydrothermal synthesis. | Xia Changjiu Lin Min Peng Xinxin Zhu Bin Xu Guangtong Shu Xingtian | 2017 | China Petroleum Processing & Petrochemical Technology2017，19，1： | 3 |
| 8 | Investigation on Organic Solvent Free Toluene Oxidative Bromination Reaction Catalyzed by HTS Zeolite显示文摘The toluene oxidative bromination reaction catalyzed by hollow titanium silicalite(HTS)zeolite in aqueous medium was investigated by employing H2O2 and HBr under mild conditions without the need for organic solvent.A high toluene conversion(90.7%)and high selectivity of mono-bromotoluene(99.0%)was achieved under the optimal reaction conditions.The UV-Raman spectroscopy was applied for the mechanism study and the result reveals that HTS is efficient for catalyzing the oxidation reaction of HBr with H2O2 to produce abundant active bromine species,which can further facilitate the toluene electrophilic bromination reaction.A two-step toluene bromination reaction mechanism involving the HTS catalyzed active bromine species“generation-conversion-utilization”process is proposed based on the UV-Raman spectroscopy analysis. | Peng Xinxin Xia Changjiu Lin Min Zhu Bin Luo Yibin Shu Xingtian | 2020 | China Petroleum Processing & Petrochemical Technology2020，22，4： | 2 |
| 9 | Environmentally-Friendly Catalytic Oxidation of Cyclohexanone with 30% H_2O_2 Solution: A Comparison Study between Hollow Titanium Silicate and Dealuminated HBEA Zeolites显示文摘Two clean liquid–phase cyclohexanone oxidation routes catalyzed by DHBEA and HTS zeolites, in the absence of organic solvents, have been developed for producing high value-added chemical intermediates. Under optimized conditions,the cyclohexanone conversion reaches up to 60%, and the selectivity of total target products(ε-caprolactone, 6-hydroxyhexanoic acid and adipic acid) is over 90% achieved by the HTS zeolite; while both cyclohexanone conversion and the 6-hydroxyhexanoic acid selectivity are over 95% obtained on the DHBEA zeolite. Both the Lewis and Br鰊sted acid sites of DHBEA zeolite can preferentially activate the carbonyl group of cyclohexanone without any impact on H_2O_2 molecules.Meanwhile, the HTS zeolite can predominantly make H_2O_2 more reactive, which agrees well with the molecular calculation results. Hence, two different Baeyer-Villiger oxidation mechanisms based on the activation of H_2O_2 and cyclohexanone are proposed. Then, 6-hydroxyhexanoic acid is formed via the ring-opening of ε-caprolactone. However, C-OH groups cannot be reactivated by DHBEA zeolite, leading to insignificant adipic acid formation, while the selectivity of adipic acid is 28.5% obtained on the HTS zeolite. Consequently, the higher catalytic performance of the DHBEA zeolite is ascribed to its larger amount of active sites and greater diffusion features than those of HTS zeolite. | Xia Changjiu Zhao Yi Zhu Bin Lin Min Peng Xinxin Dai Zhenyu Shu Xingtian | 2018 | China Petroleum Processing & Petrochemical Technology2018，20，4： | 2 |
| 10 | Effect of photoionisation on initial discharge in air under nanosecond pulse voltage显示文摘Effects of photoionisation on the development and electron runaway of the initial discharge in atmospheric air under nanosecond pulse voltage were studied via twodimensional particle-in-cell/Monte Carlo collision simulations.It was found that photoionisation has little effect at the beginning of the initial discharge.However,as the discharge channel gradually develops towards the anode,photoionisation shows greater impacts on the morphology of discharge but has little influence on the velocity of discharge development.Photoionisation does not appear to have a decisive effect on the growth trend of the highest energy of runaway electrons,but it does affect the change rate of the highest energy and overall distribution of electron energy,resulting in a higher proportion of energetic electrons.The difference in the distributions of the electron energy between the two cases,with and without considering photoionisation,can be attributed to the impact of photoionisation on the discharge morphology,which in turn distorted the electric field.The spatial density distributions of the electrons produced by photoionisation further explained the differences.The authors’results explicitly demonstrate the influence of photoionisation on the development and the electron runaway of the initial discharge under nanosecond pulse voltage,which provides more comprehensive knowledge for the atmospheric air gap nanosecond pulse discharge physics. | Yutai Li Yangyang Fu Zhigang Liu Handong Li Peng Wang Haiyun Luo Xiaobing Zou Xinxin Wang | 2023 | High Voltage2023，8，2： | 2 |
| 11 | A novel spoof surface plasmon polariton structure to reach ultra-strong field confinements显示文摘Ultrathin corrugated metallic structures have been proved to support spoof surface plasmon polariton (SPP) modes on two-dimension (2D) planar microwave circuits.However,to provide stronger field confinement,larger width of strip is required to load deeper grooves,which is cumbersome in modern large-scale integrated circuits and chips.In this work,a new spoof SPP transmission line (TL) with zigzag grooves is proposed.This new structure can achieve stronger field confinement compared to conventional one with the same strip width.In other words,the proposed spoof SPP TL behaves equivalently to a conventional one with much larger size.Dispersion analysis theoretically indicates the negative correlation between the ability of field confinement and cutoff frequencies of spoof SPP TLs.Numerical simulations indicate that the cutoff frequency of the proposed TL is lower than the conventional one and can be easily modified with the fixed size.Furthermore,two samples of the new and conventional spoof SPP TLs are fabricated for experimental demonstration.Measured S-parameters and field distributions verify the ultra-strong ability of field confinement of the proposed spoof SPP TL.Hence,this novel spoof SPP structure with ultra-strong field confinement may find wide applications in microwave and terahertz engineering. | Pei Hang He Hao Chi Zhang Xinxin Gao Ling Yun Niu Wen Xuan Tang Jiayuan Lu Le Peng Zhang Tie Jun Cui | 2019 | Opto-Electronic Advances2019，2，6： | 2 |
| 12 | The impact of the atmospheric turbulence-development tendency on new particle formation:a common finding on three continents显示文摘A new mechanism of new particle formation(NPF)is investigated using comprehensive measurements of aerosol physicochemical quantities and meteorological variables made in three continents,including Beijing,China;the Southern Great Plains site in the USA;and SMEARⅡStation in Hyytiala,Finland.D espite the considerably different emissions of chemical species among the sites,a common relationship was found between the characteristics of NPF and the stability intensity.The stability parameter(ζ=Z/L,where Z is the height above ground and L is the Monin-Obukhov length)is found to play an important role;it drops significantly before NPF as the atmosphere becomes more unstable,which may serve as an indicator of nucleation bursts.As the atmosphere becomes unstable,the NPF duration is closely related to the tendency for turbulence development,which influences the evolution of the condensation sink.Presumably,the unstable atmosphere may dilute pre-existing particles,effectively reducing the condensation sink,especially at coarse mode to foster nucleation.This new mechanism is confirmed by model simulations using a molecular dynamic model that mimics the impact of turbulence development on nucleation by inducing and intensifying homogeneous nucleation events. | Hao Wu Zhanqing Li Hanqing Li Kun Luo Yuying Wang Peng Yan Fei Hu Fang Zhang Yele Sun Dongjie Shang Chunsheng Liang Dongmei Zhang Jing Wei Tong Wu Xiaoai Jin Xinxin Fan Maureen Cribb Marc L.Fischer Markku Kulmala Tuukka Petaja | 2021 | National Science Review2021，8，3： | 2 |
| 13 | Deactivation Behavior of Hollow Titanium Silicalite Zeolite in Aqueous Ammonia Solution under Simulated Industrial Cyclohexanone Ammoximation Conditions显示文摘For simulating the real deactivation of hollow titanium silicalite(HTS) zeolite in commercial ammoximation process, HTS was treated by 10% NH_3·H_2O solution at 120 ℃ in stirred autoclave. It is found that a part of HTS zeolite crystals dissolved in the hot NH_3·H_2O solution, and the specific surface area and pore volume continuously decreased with the increase in NH_3 hydrothermal treatment time. Meanwhile, the transformation of framework Ti species into extraframework Ti species was detected by the spectroscopic methods. However, the extraframework Ti species were still in a highly dispersed state after the hydrothermal and thermal treatments as shown by TEM images, while the formation of new acid sites was not detected. Upon combining the results of characterization with catalytic performance of HTS, the main deactivation reason for this material had been determined, which might be attributed to the reduction of specific surface area and active centers after basic treatment and calcination of HTS samples. And then the possible mechanism of simulated deactivation of HTS zeolite was proposed, which could describe the elemental reaction steps much more visually and directly. | Xia Changjiu Lin Min Peng Xinxin Zhu Bin Xu Guangtong Shu Xingtian | 2016 | China Petroleum Processing & Petrochemical Technology2016，18，4： | 2 |
| 14 | Anchoring Single Nickel Atoms on Carbon-vacant Carbon Nitride Nanosheets for Efficient Photocatalytic Hydrogen Evolution显示文摘Polymeric carbon nitride(PCN)has emerged as a promising candidate for photocatalytic hydrogen evolution,but its dependence on scarce and high-cost noble metal co-catalysts severely limits its extensive application.It will be of great promise to develop non-noble metal single-atom co-catalysts with low-cost and high atom utilization to improve the photocatalytic performance over PCN.Herein,single Ni atoms are successfully anchored onto carbon-vacant PCN nanosheets(CCN-SANi)via a two-step ammonia thermal treatment and photo-deposition process.Theoretical calculations and experimental results demonstrate that the optical absorption property and the charge transfer ability of CCN-SANi have been significantly improved with the introduction of single Ni atoms to form Ni-N3 sites.In comparison to carbon-vacant PCN(CCN)loaded with Ni clusters,the obtained CCN-SANi exhibits 11.4 times increased photocatalytic performance,with the highest hydrogen evolution rate reaching 511μmol/(g·h),which is even 1.7 times higher than that of CCN loaded with Pt clusters.This research proposes an inspiring and reliable strategy to design novel single-atom semiconducting polymers with electronic structures manipulated for efficient photocatalysis. | LIN Zhi ZHANG Zhengqi WANG Yiqing PENG Zhiming WANG Xinxin WANG Ruizhe HUANG Yu-Cheng MENG Fanqi LI Mingtao DONG Chung-Li ZHANG Qinghua GU Lin SHEN Shaohua | 2022 | Chemical Research in Chinese Universities2022，38，5： | 1 |
| 15 | Template-free synthesis of monodisperse a-Fe203 porous ellipsoids and their application to gas sensors显示文摘 | Sun Peng He Xinxin Wang Wenbo | 2012 | Cryst Eng Commun2012，14，6： | 1 |
| 16 | Mecha- nism for resistive switching in an oxide-based electro- chemical metallization memory显示文摘 | Peng Shanshan Zhuge Fei Chen Xinxin | 2012 | Applied Physics Letters2012，100，72： | 1 |
| 17 | MiR-378a-3p acts as a tumor suppressor in gastric cancer via directly targeting RAB31 and inhibiting the Hedgehog pathway proteins GLI1/2显示文摘Objective:To improve the prognosis of patients with gastric cancer(GC),more effective therapeutic targets are urgently needed.Increasing evidence indicates that miRNAs are involved in the progression of various tumors,and RAS-associated protein in the brain 31(RAB31)is upregulated and promotes the progression of multiple malignant tumors.Here,we focused on identifying RAB31-targeted miRNAs and elucidating their potential mechanism in the progression of GC.Methods:RAB31 and miR-378a-3p expression levels were detected in paired fresh GC tissues and GC cell lines.Bioinformatics analysis was used to predict the miRNAs targeting RAB31 and the relationships between RAB31 and other genes.Dual-luciferase reporter assays were applied to verify the targeted interaction relationship.CCK-8,colony formation,flow cytometry,wound healing,and Transwell assays were performed to assess the proliferation,apoptosis,migration,and invasion of GC cells.Tumorsphere formation assays were performed to assess the stemness of gastric cancer stem cells.Related proteins were detected by Western blot.Xenograft assays in nude mice were performed to explore the effect of miR-378a-3p in vivo.Results:We report the first evidence that miR-378a-3p is downregulated in GC,whereas its overexpression inhibits proliferation,invasion,and migration as well as promotes apoptosis in GC cells.Mechanistically,miR-378a-3p inhibits the progression of GC by directly targeting RAB31.Restoring RAB31 expression partially offsets the inhibitory effect of miR-378a-3p.Further research revealed that miR-378a-3p inhibits GLI1/2 in the Hedgehog signaling pathway and attenuates the stemness of gastric cancer stem cells.Finally,xenograft assays showed that miR-378a-3p inhibits GC tumorigenesis in vivo.Conclusions:MiR-378a-3p inhibits GC progression by directly targeting RAB31 and inhibiting the Hedgehog signaling pathway proteins GLI1/2. | Xinxin Xu Yang Li Guoxiao Liu Kai Li Peng Chen Yunhe Gao Wenquan Liang Hongqing Xi Xinxin Wang Bo Wei Hongtao Li Lin Chen | 2022 | Cancer Biology & Medicine2022，19，12： | 1 |
| 18 | Transcriptomic analysis reveals the defense mechanisms of citrus infested with Diaphorina citri显示文摘Huanglongbing(HLB) is a devastating disease that has led to an acute crisis for growers of citrus, one of the world's most important fruit crops. The phloem-feeding Asian citrus psyllid(ACP), Diaphorina citri, is the main pest at the new shoot stage and is the only natural vector of HLB pathogenic bacteria. Little is known about how plants perceive and defend themselves from this destructive pest. Here, we characterized changes in the expression of various genes in citrus plants that were continuously infested by D. citri for different durations(12, 24, and 48 h). A total of 5 219 differentially expressed genes(DEGs) and 643 common DEGs were identified across all time points. Several pathways related to defense were activated, such as peroxisome, alpha-linolenic acid metabolism, and phenylpropanoid and terpenoid biosynthesis, and some pathways related to growth and signal transduction were suppressed in response to D. citri infestation. The expression of genes including kinases(CML44, CIPK6, and XTH6), phytohormones(SAMT, LOX6, and NPR3), transcription factors(bHLH162, WRKY70, and WRKY40), and secondary metabolite synthesis-related genes(PAL, 4CL2, UGT74B1 and CYP82G1) was significantly altered in response to D. citri infestation. The findings of this study greatly enhance our understanding of the mechanisms underlying the defense response of citrus plants to D. citri infestation at the molecular level. Functional characterization of the candidate defense-related genes identified in this study will aid the molecular breeding of insect-resistant citrus varieties. | Xueli Sun Ting Yu Minliang Bin Chunhua Hu Fangcheng Bi Xinxiang Peng Ganjun Yi Xinxin Zhang | 2023 | Horticultural Plant Journal2023，9，3： | 1 |
| 19 | Knockdown of midgut genes by dsRNA-transgenic plant- mediated RNA interference in the hemipteran insect Ni- laparvata lugens 显示文摘 | Zha Wenjun Peng Xinxin Chen Rongzhi | 2011 | PLoS One2011，6，20： | 1 |
| 20 | Oxidative modifications and structural changes of human serum albumin in response to air dielectric barrier discharge plasma显示文摘In this work,the air dielectric barrier discharge plasma was applied to a model of protein human serum albumin to explore plasma‐mediated protein damage from a biomolecular perspective.Carbonylation and side chain modifications of protein in solution were observed by Fourier transform infrared(FT‐IR)spectroscopy and mass spectrometry(MS).Protein backbone cleavage is proved by Bradford assay,sodium dodecyl sulphate–polyacrylamide gel electrophoresis,and MS.Typical fragments are in the range of 10–12 kDa.The decrease inα‐helix and increase inβ‐sheet indicated by FT‐IR are major protein secondary structure changes.Accordingly,a whole map of protein oxidative damage and structural changes in response to the plasma was postulated. | Siqi Peng Liyang Zhang Dongheyu Zhang Yuntao Guo Xinxin Wang Qun Zhou Haiyun Luo | 2021 | High Voltage2021，6，5： | 1 |
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