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| 1 | Robotic total meso-rectal excision for rectal cancer: A systematic review following the publication of the ROLARR trial显示文摘AIM To compare outcomes in patients undergoing rectal resection by robotic total meso-rectal excision(RTME) vs laparoscopic total meso-rectal excision(LTME).METHODS Standard medical electronic databases such as Pub-Med, MEDLINE, EMBASE and Scopus were searched to find relevant articles. The data retrieved from all types of included published comparative trials in pati-ents undergoing RTME vs LTME was analysed using the principles of meta-analysis. The operative, post-operative and oncological outcomes were evaluated to assess the effectiveness of both techniques of TME. The summated outcome of continuous variables was expressed as standardized mean difference(SMD) and dichotomous data was presented in odds ratio(OR).RESULTS One RCT(ROLARR trial) and 27 other comparative studies reporting the non-oncological and oncological outcomes following RTME vs LTME were included in this review. In the random effects model analysis using the statistical software Review Manager 5.3, the RTME was associated with longer operation time(SMD, 0.46; 95%CI: 0.25, 0.67; z = 4.33; P = 0.0001), early passage of first flatus(P = 0.002), lower risk of conversion(P = 0.00001) and shorter hospitalization(P = 0.01). The statistical equivalence was seen between RTME and LTME for non-oncological variables like blo-od loss, morbidity, mortality and re-operation risk. The oncological variables such as recurrence(P = 0.96), number of harvested nodes(P = 0.49) and positive circumferential resection margin risk(P = 0.53) were also comparable in both groups. The length of distal resection margins was similar in both groups. CONCLUSION RTME is feasible and oncologically safe but failed to demonstrate any superiority over LTME for many sur-gical outcomes except early passage of flatus, lower risk of conversion and shorter hospitalization. | Katie Jones Mohamed G Qassem Parv Sains Mirza K Baig Muhammad S Sajid | 2018 | World Journal of Gastrointestinal Oncology2018，10，11： | 4 |
| 2 | Effect of a multifactorial intervention on mortality in type 2 diabetes显示文摘 | Gaede P Parving HH Pedersen O | | New England Journal of Medicine0，，： | 3 |
| 3 | Optimum Design of Outrigger and Belt Truss Systems Using Genetic Algorithm显示文摘 | Radu Hulea Bianca Parv Monica Nicoreac Bogdan Petrina | 2014 | Journal of Civil Engineering and Architecture2014，8，6： | 2 |
| 4 | Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial显示文摘 | Dick de Zeeuw Rajiv Agarwal Michael Amdahl Paul Audhya Daniel Coyne Tushar Garimella Hans-Henrik Parving Yili Pritchett Giuseppe Remuzzi Eberhard Ritz Dennis Andress | 2010 | The Lancet . 2010 (9752)2010，，9752： | 2 |
| 5 | Effect of a multifactorial intervention on mortality in type 2 diabetes显示文摘 | Goede P Lund-Andersen H Parving HH | 2008 | N Engl J Med2008，358，6： | 1 |
| 6 | Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy显示文摘 | Cooper ME De Zeeuw D Keane WF Mitch WE Parving H-H | 2001 | N Engl J Med2001，345，12： | 1 |
| 7 | Double-blind,randomized study of the effect of combined treatment with VC and VE on albuminura in type 2 diabetic patients显示文摘 | Gaaede P Poulse H E Parving H H | 2001 | Diabet Med2001，18，： | 1 |
| 8 | Increased left ventricular mass in normotensive type 1 diabetic patients with diabetic nephropathy显示文摘 | Sato A Tarnow L Parving HH | 1998 | Diabetes Care1998，21，9： | 1 |
| 9 | Hearing screening-aspects of epidemiology and identification of hearing impaired children显示文摘 | Parving A | 1999 | Int J Pediatr Otorhinolaryngol1999，5，： | 1 |
| 10 | Albuminuria atherapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy 显示文摘 | De Zeeuw D Remuzzi G Parving HH | 2004 | Circulation2004，110，8： | 1 |
| 11 | The Effect of Irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes显示文摘 | Parving HH Lehnert H Brochner-Mortensen J | 2001 | New Engl J Med2001，345，12： | 1 |
| 12 | Nitric oxide biochemistry pathophysiology and detection显示文摘 | Parv E | 1993 | N Eng J Med1993，328，： | 1 |
| 13 | Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno-2 study显示文摘 | EDE P H JEPSEN P V PARVING H H | 1999 | Ugeskr Laeger1999，161，30： | 1 |
| 14 | 显示文摘 | Parving HH Lehnert H Broehner-Mortensen J | 2001 | N Engl J Med2001，345，12： | 1 |
| 15 | The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabettes显示文摘 | Parving HH Lehnert H Brochner MJ | 2001 | N Engl J Med2001，345，9： | 1 |
| 16 | The effect of in- travenous insulin infusion on kidney function in insulin-dependent diabetes mellitus显示文摘 | Sandahl-Christiansen J Frandsen M Parving H | 1981 | Diabetologia1981，20，3： | 1 |
| 17 | Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial显示文摘 | Dick de Zeeuw Rajiv Agarwal Michael Amdahl Paul Audhya Daniel Coyne Tushar Garimella Hans-Henrik Parving Yili Pritchett Giuseppe Remuzzi Eberhard Ritz Dennis Andress | 2010 | The Lancet2010，，9752： | 1 |
| 18 | Aliskiren combined with losartan in type 2 diabetes and nephropathy 显示文摘 | Parving HH Persson F Lewis JB | 2008 | N Engl J Med2008，358，23： | 1 |
| 19 | Stroke in pa- tients with type 2 diabetes mellitus, chronic kidney disease, and anemia treated with Darbepoetin Alfa: the trial to reduce cardiovascular events with Aranesp therapy (TREAT) experience显示文摘 | Skali H Parving HH Parfrey PS | 2011 | Circulation2011，124，25： | 1 |
| 20 | Effect of a mul-tifactorial intervention on mortality in type 2 diabetes显示文摘 | Gaede P Lund-Andersen H Parving HH | 2008 | N En-gl J Med2008，358，： | 1 |
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