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| 1 | Gilbert's syndrome: High frequency of the (TA)_7 TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 gene显示文摘瞄准:在吉伯的症候群(GS ) 在 UDP-glucuronosyltransferase 1 (UGT1A1 ) 基因识别变体并且在印度在正常控制之中在 TA 插入和它的影响的印度,以及频率为 TA 插入和 GS 估计在纯合性之间的协会。方法:95 个 GS 盒子和 95 正常控制被选择。肝工作,另外的测试被做。倡导者和 UGT1A1 基因的所有 5 前 ons 被重新定序。对新奇 trinucleotide 插入的功能的评价被做由在 silico 分析并且由估计 UGT1A1,倡导者活动在 Hep G2 由适当构造的酶记者试金执行了房间线。结果:在 GS 病人之中, 80% 为 TA 插入是同型结合的,它比从另外的种族组的报告高好几倍。吝啬的 UCB 水平与仅仅这插入的一个拷贝在个人之中被提高,它不与有二个拷贝的那些显著地不同。在 UGT1A1 基因的许多新 DNA 变体被发现,包括在倡导者的插入在 GS 病人的一个子集(10%) 发现了的 trinucleotide (猫) ,然而并非在正常之中控制。In-silico 分析证明在倡导者和功能的分析的合拢 DNA 的显著变化在 UGT1A1 基因源于这插入的抄写效率显示出 20 褶层减小,显著地从而提高 UCB 水平。结论:GS 的基因传染病学越过种族组是可变的,在 UGT1A1 倡导者变体之中的上位相互作用调制胆红素 glucuronidation。 | Shabana Farheen Sanghamitra Sengupta Amal Santra Suparna Pal Gopal Krishna Dhali Meenakshi Chakravorty Partha P Majumder Abhijit Chowdhury | 2006 | World Journal of Gastroenterology2006，12，14： | 29 |
| 2 | Liver abscess caused by Burkholderia pseudomallei in a young man: A case report and review of literature显示文摘Pyogenic liver abscess is a common entity in Indian subcontinent and is mostly caused by gram negative bacteria. Melioidosis is not commonly seen in India and only a few cases are reported. It can give rise to multiple abscesses at different sites including liver. We report a case of isolated liver abscess caused by Burkholderia pseudomallei(B. pseudomallei) in a 29-yearold recently diagnosed diabetic, immunocompetent male. Diagnosis was made by imaging and culture of pus aspirated from the abscess and he was treated with percutaneous pigtail catheter drainage followed by antibiotics(meropenem and trimethoprim-sulphmethoxazole). Melioidosis is an emerging infection in India and has high mortality rate, so early diagnosis and promptmanagement is warranted which requires clinical vigilance and an intensive microbiological workup. Clinicians should be aware of isolated liver abscess caused by B. pseudomallei in appropriate clinical settings. | Partha Pal Sayantan Ray Avijit Moulick Subhasis Dey Anirban Jana Kokila Banerjee | 2014 | World Journal of Clinical Cases2014，2，10： | 3 |
| 3 | Fine needle aspiration diagnosis of isolated pancreatic tuberculosis: A case report显示文摘Tuberculosis(TB) involving the pancreas are uncommon, especially when present in immunocompetent hosts. Pancreatic TB is more frequently associated with miliary TB or widely disseminated disease. Pancreatic TB may present as cystic or solid pancreatic masses, pancreatic abscess or acute or chronic pancreatitis. Majority of the cases are diagnosed after surgical exploration for presumed pancreatic malignancy and preoperative diagnosis is quite difficult. However, improvement in imaging techniques and the resulting imageguided interventions gradually can obviate the need for more invasive diagnostic surgical procedures and expedite the planning of therapy. Herein, we report a rare case of isolated pancreatic TB which presented with pancreatic mass lesion in an immunocompetent host. Diagnosis was made by contrast enhanced computed tomography and guided fine needle aspiration of the pancreatic mass which revealed acid-fast bacillion Ziehl-Neelsen stain. The case was treated successfully with antituberculous drugs. Pancreatic tuberculosis should be considered in the differential diagnosis of a pancreatic mass when the patient is young, residing in the endemic zone of tuberculosis. Every attempt should be made to diagnose the cases to prevent unnecessary operation. | Nikhil Sonthalia Sayantan Ray Partha Pal Avishek Saha Arunansu Talukdar | 2013 | World Journal of Clinical Cases2013，1，5： | 2 |
| 4 | Modeling of electrical discharge machining process using back propagation neural network and multi-objective optimization using non- dominating sorting genetic algorithm-II显示文摘 | Debabrata Mandal Surjya K Pal Partha Saha | 2007 | Journal of Materials Processing Technology2007，，186： | 1 |
| 5 | Modeling of electrical discharge machining process using back propagation neural network and multi-objective optimization using non-dominating sorting genetic algorithm-Ⅱ显示文摘 | Debabrata Mandal Surjya K Pal Partha Saha | 2007 | Journal of Materials Processing Technology2007，186，： | 1 |
| 6 | Spectral Triples and Associated Connes-de Rham Complex for the Quantum SU (2) and the Quantum Sphere显示文摘 | Partha Sarathi Chakraborty Arupkumar Pal | 2003 | Communications in Mathematical Physics2003，，3： | 1 |
| 7 | Modeling of electrical discharge machining process using back propagation neural network and multi-objective optimization using non-dominating sorting genetic algorithm-Ⅱ显示文摘 | Mandal Debabrata Pal Surjya K Saha Partha | 2007 | Journal of Materials Processing Technology2007，186，13： | 1 |
| 8 | Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell–specific signal transducer and activator of transcription 3 gene knockout mice显示文摘 | Norio Horiguchi Fouad Lafdil Andrew M. Miller Ogyi Park Hua Wang Mohanraj Rajesh Partha Mukhopadhyay Xin Yuan Fu Pal Pacher Bin Gao | 2010 | Hepatology2010，，5： | 1 |
| 9 | Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats显示文摘 | Pal Pacher Takahiro Nagayama partha Mukhopadhyay | 2008 | Nat Protoc2008，3，9： | 1 |
| 10 | Equivariant Spectral Triples on the Quantum SU(2) Group显示文摘 | Partha Sarathi Chakraborty Arupkumar Pal | 2003 | K - Theory2003，，2： | 1 |
| 11 | Heterogeneity of non-alcoholic fatty liver disease: Implications for clinical practice and research activity显示文摘Non-alcoholic fatty liver disease(NAFLD)is a heterogeneous condition with a wide spectrum of clinical presentations and natural history and disease severity.There is also substantial inter-individual variation and variable response to a different therapy.This heterogeneity of NAFLD is in turn influenced by various factors primarily demographic/dietary factors,metabolic status,gut microbiome,genetic predisposition together with epigenetic factors.The differential impact of these factors over a variable period of time influences the clinical phenotype and natural history.Failure to address heterogeneity partly explains the sub-optimal response to current and emerging therapies for fatty liver disease.Consequently,leading experts across the globe have recently suggested a change in nomenclature of NAFLD to metabolic-associated fatty liver disease(MAFLD)which can better reflect current knowledge of heterogeneity and does not exclude concomitant factors for fatty liver disease(e.g.alcohol,viral hepatitis,etc.).Precise identification of disease phenotypes is likely to facilitate clinical trial recruitment and expedite translational research for the development of novel and effective therapies for NAFLD/MAFLD. | Partha Pal Rajan Palui Sayantan Ray | 2021 | World Journal of Hepatology2021，13，11： | 1 |
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