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| 1 | Cardiorenal biomarkers in acute heart failure显示文摘与心失败(HF ) 管理病人是在肾的功能能极大地增加的变得更坏联系的本身,而是存在以内的一项挑战性的任务死亡和病态。早诊断和治疗是钥匙阻止再进医院和还原剂保健费用。Biomarkers 长在与 HF 诊断和预言的病人作为高度敏感、特定的工具被建立了。思考不同 pathophysiological 事件和进行中的细胞的侮辱, biomarkers 被证明优异到常规实验室测试。更好的试金和快速的分析的可获得性作为紧急情况部门并且在病人的床边的 point-of-care 测试允许 biomarkers 的使用。尖锐 HF 病人经常继续发展变得更坏肾的功能,称为的同样尖锐的 cardiorenal 症候群。研究的成长宽度显示出联合多重 biomarkers 更好制定结果并且在如此的病人生产理想的结果的含意。 | Rajiv Choudhary Dipika Gopal Ben A. Kipper Alejandro De La Parra Landa Hermineh Aramin Elizabeth Lee Saloni Shah Alan S. Maisel | 2012 | Journal of Geriatric Cardiology2012，9，3： | 4 |
| 2 | Developing Flexible Dual Master's Degree Programs at UPAEP (Universidad Popular Autonoma del Estado de Puebla) and OSU (Oklahoma State University)显示文摘 | Mafia G. Fabregas-Janeiro Pablo Nuno de la Parra | 2012 | US-China Education Review(A)2012，2，2： | 2 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Low cost navigation system for UAV's显示文摘 | Sergio de La Parra Javier Angel | 2005 | Aerospace Science and Technology2005，9，6： | 1 |
| 5 | Lipid bilayers including cholesterol as vehicles for acid dyes in wool dyeing显示文摘 | De la Maza A Parra J L Manich A | 1993 | Textile Research Journal1993，63，11： | 1 |
| 6 | Comparison of doxorubicin-eluting bead transarterial chemoembolization (DEB-TACE) with conventional transarterial chemoembolization (TACE) for the treatment of hepatocellular carcinoma显示文摘 | Ferrer Puchol M D la Parra C Esteban E | 2011 | Radiologia2011，53，3： | 1 |
| 7 | Heavy metal distribution in dust from elementary schools in Hermosillo, Sonora, Mexico 显示文摘 | Meza-Figueroa D De la O-Villanueva M De la Parra M L | 2007 | ATMOSPHERIC ENVIRONMENT2007，14，2： | 1 |
| 8 | Dyeing wool at low temperatures:new method using liposomes显示文摘 | Marti M De La Maza A Parra J L | 2001 | Textile Research Journal2001，71，8： | 1 |
| 9 | Validation of a nomogram to predict the risk of nonsentinel lymph node metastases in breast cancer patients with a positive sentinel node biopsy: validation of the MSKCC breast nomogram显示文摘 | van la Parra RF Ernst MF Bevilaequa JL | 2009 | Ann Surg Oncol2009，16，5： | 1 |
| 10 | Heavy metal distribution in dust from elementary school in Hermosillo, Sonora, Mexico显示文摘 | DIANA MEZA-FIGUEROA MARGARITA DE LA O-VILLANUEVA MARIA LUISA DE LA PARRA | 2007 | Atmospheric Environment2007，41，： | 1 |
| 11 | Surfactants in wool chlorination显示文摘 | De La Maza A Leal J S Parra J L | 1991 | Textile Research Journal1991，61，2： | 1 |
| 12 | Comparison ofdoxorubicin-eluting bead transarterial chemoembolization ( DEB-TACE ) with conventional transarterial chemoembolization(TACE ) for the treatment of hepatocellular carcinoma 显示文摘 | Ferrer Puchol MD la Parra C Esteban E | 2011 | Radiologia’2011，53，3： | 1 |
| 13 | The valu1 of sentinel lymph node biopsy in duetal carcinoma in sit1 (DCIS) and DCIS with microinvasion of the breast 显示文摘 | van la Parra RF Ernst MF Barneveld PC | 2008 | Eur J Surg Oncol2008，34，6： | 1 |
| 14 | Use of a fluorescence spectroscopy technique to study the adsorption of sodium dodecylsulfonate on liposomes显示文摘 | M Cócera O López J Estelrich J.L Parra A de la Maza | 2001 | Chemistry and Physics of Lipids2001，，1： | 1 |
| 15 | Extracellular polymeric substances (EPS) in upflow anaerobic sludge blanket (VASB) reactors operated under high salinity conditions显示文摘 | Ismail S B de La Parra CJ Temmink H | 2010 | Water Research2010，44，6： | 1 |
| 16 | Meta-analysis of predic- tive factors for non-sentinel lymph node metastases in breast cancer patients with a positive SLN显示文摘 | van la Parra RF Peer PG Ernst MF | 2011 | Eur J Surg Oncol2011，37，4： | 1 |
| 17 | Low cost navigation system for UAV's 显示文摘 | PARRA S de La ANGEL J | 2005 | Aerospace Science and Technology2005，9，： | 1 |
| 18 | Effect of selective digestive decontamination on the nosocomial infection and multiresistant microorganisms incidence in critically ill patients显示文摘 | Parra Moreno M L Arias Rivera S la Cal Lopez M A | | 0，，10： | 1 |
| 19 | Low cost navigation system for UAV’s ☆ ☆ This article was presented at ODAS 2004.显示文摘 | Sergio de La Parra Javier Angel | 2005 | Aerospace Science and Technology2005，，6： | 1 |
| 20 | UPAEP High School Summer Academy at Oklahoma State University显示文摘 | Maria G. Fabregas Janeiro Pablo Nuno de la Parra Blanca Elena Lozano | 2013 | US-China Education Review(B)2013，3，10： | 1 |
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