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| 1 | Factors associated with incomplete small bowel capsule endoscopy studies显示文摘AIM:To identify patient risk factors associated with incomplete small bowel capsule endoscopy(CE) studies.METHODS:Data from all CE procedures performed at St.Paul's Hospital in Vancouver,British Columbia,Canada,between December 2001 and June 2008 were collected and analyzed on a retrospective basis.Data collection for complete and incomplete CE study groups included patient demographics as well as a number of potential risk factors for incomplete CE including indication for the procedure,hospitalization,diabetes mellitus with or without end organ damage,limitations in mobility,renal insufficiency,past history of bowel obstruction,abdominal surgery,abdominal radiation therapy and opiate use.Risk factors were analyzed using a univariable and multivariable logistic regression model.RESULTS:From a total of 535 CE procedures performed,158 were incomplete(29.5%).The univariable analysis showed that CE procedures performed for overt gastrointestinal bleeding(P = 0.002),and for patients with a prior history of abdominal surgery(P = 0.023) or bowel obstruction(P = 0.023) were significantly associated with incomplete CE studies.Patients on opiate medications(P = 0.094) as well as hospitalized patients(P = 0.054) were not statistically significant,but did show a trend towards incomplete CE.The multivariable analysis showed that independent risk factors for an incomplete CE procedure include prior history of bowel obstruction [odds ratios(OR) 2.77,P = 0.02,95% confidence intervals(CI):1.17-6.56] and procedures performed for gastrointestinal bleeding(Occult OR 2.04,P = 0.037,95% CI:1.04-4.02 and Overt OR 2.69,P = 0.002,95% CI:1.44-5.05).Patients with a prior history of abdominal surgery(OR 1.46,P = 0.068,95% CI:0.97-2.19),those taking opiate medications(OR 1.54,P = 0.15,95% CI:0.86-2.76) and hospitalized patients(OR 1.82,P = 0.124,95% CI:0.85-3.93) showed a trend towards statistical significance.CONCLUSION:We have identified a number of risk factors for incomplete CE procedures that can be used to risk-stratify patients and guide interventions to improve completion rates. | Mitchell M Lee Andrew Jacques Eric Lam Ricky Kwok Pardis Lakzadeh Ajit Sandhar Brandon Segal Sigrid Svarta Joanna Law Robert Enns | 2010 | World Journal of Gastroenterology2010，16，42： | 10 |
| 2 | 糖尿病患者血清胱抑素C和急性反应指标与视网膜病变严重程度相关性研究(英文)显示文摘目的:评估糖尿病视网膜病变(DR)严重程度与血清胱抑素C和急性时相反应指标的相关性,包括红细胞沉降率(ESR)和超敏C反应蛋白(hs-CRP)。方法:研究纳入了1mo内就诊的所有糖尿病视网膜病患者。患者均记录人口统计学数据。行眼科检查,同时检测糖化血红蛋白(Hb A1c)、ESR、hs-CRP和血清胱抑素C水平。结果:研究包括67例糖尿病患者,其中19例(28.3%)无视网膜病变患者,22例(32.8%)非增殖型视网膜病变患者和26例(38.8%)增殖型视网膜病变患者。三组间平均年龄、性别分布、平均糖尿病病程、高血压和血脂异常患病率、吸烟状况以及Hb A1c水平无明显差异。随着视网膜病变发展,平均血清胱抑素C水平显著提高,三组分别为1.1±0.48,1.22±0.38,1.71±0.92(P=0.007)。在多元回归分析中,仅血清胱抑素C与糖尿病视网膜病变严重程度有关(P=0.025)。结论:研究表明,在独立于急性时相反应指标,血清胱抑素C水平随DR加重升高。因此,该结论可作为初级医护人员区分高危患者的标志。 | Joobin Khadamy Gholamhossein Yaghoobi Abbas Hosseini Rad Mahnaz Najafi Saeed Reza Heydari Pardis Khademi | 2018 | 国际眼科杂志2018，18，3： | 8 |
| 3 | Overlapping gastroesophageal reflux disease and irritable bowel syndrome:Increased dysfunctional symptoms显示文摘AIM:To investigate the association of gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) in Iranian patients and examine the prevalence of functional symptoms of the gastrointestinal tract in patients presenting with either IBS, GERD or both.METHODS: Six thousand four hundred and seventy six patients presented to the Gastro-intestinal (GI) clinic with symptoms of functional dysfunction of GI tract, 1419 patients (62.0% women, 38.0% men; mean age: 37.4±11.5 years) met Rome or Rome criteria(depending on the year of diagnosis)for IBS.2658 patients were diagnosed with GERD based on clinical presentation and endoscopic findings.We assessed other functional symptoms(epigastric pain,nausea,vomiting,belching,constipation and diarrhea)in patients suffering from GERD,IBS or both.RESULTS: Among IBS subjects, 63.6% (69.0% women, 31.0% men; mean age: 36.4±10.3 years) also hadGERD, whereas 34.7% of the non-IBS patients had GERD [odds ratio (OR) =3.2, 95% confidence interval (CI): 2.9-3.7, P<0.0001]. Among patients with GERD, 33.9% of subjects met Rome criteria compared to 13.5% of non-GERD patients (OR=3.6, 95% CI: 3.1-4.3, P<0.0001). Prevalence of all functional symptoms was higher in overlapping GERD and IBS subjects, when compared with their prevalence in the IBS subjects without GERD or GERD only subjects (P<0.05).CONCLUSION: This finding shows that in overlapping GERD and IBS, other functional abnormalities of the GI tract are also highly prevalent, suggesting a common underlying dysfunction. | Shadi Sadeghi Yarandi Siavosh Nasseri-Moghaddam Pardis Mostajabi Reza Malekzadeh | 2010 | World Journal of Gastroenterology2010，16，10： | 5 |
| 4 | Risk of Cerebrovascular Accidents and Ischemic Heart Disease in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis显示文摘 | Siddharth Singh Harkirat Singh Edward V. Loftus Darrell S. Pardi | 2014 | Clinical Gastroenterology and Hepatology2014，，3： | 3 |
| 5 | Effects of Fenofibrate Treatment on Cardiovascular Disease Risk in 9,795 Individuals With Type 2 Diabetes and Various Components of the Metabolic Syndrome显示文摘 | Scott Russell O’Brien Richard Fulcher Greg Pardy Chris d’Emden Michael Tse Dana Taskinen Marja-Riitta Ehnholm Christian Keech Anthony | 2009 | Diabetes Care2009，，： | 2 |
| 6 | Dominance order in Polistes wasps显示文摘 | PARDI L | 1948 | Physiological Zoology1948，21，1： | 1 |
| 7 | Structure and flexibility of the complete periplasmic domain of BamA:the protein insertion machine of the outer membrane显示文摘 | Gatzeva-Topalova PZ Warner LR Pardi A Sousa MC | | 0，，11： | 1 |
| 8 | Review of the Micro- scopic Colitides显示文摘 | Yen E F Pardi D S | 2011 | Current Gastroen-terology Reports2011，13，5： | 1 |
| 9 | Evolution of spiral galaxies,4:The thick disk in the solar region as an intermediate collapse phase显示文摘 | PARDI M C FERRINI F | 1995 | The Astrophysical Journal1995，444，： | 1 |
| 10 | Transfemeral intraluminal graft implantation for abdominal aortic aneurysms 显示文摘 | Pardi JC Palmaz JC Barone HD | 1991 | Ann Vasc Surg1991，5，： | 1 |
| 11 | Three dimensional ultrasound in small parts:is it just a nice picture显示文摘 | Femandz LJ Aguilar A Pardi S | | 0，，03： | 1 |
| 12 | Use of montelukast as steroid- sparing agent for recurrent eosinophilic gastroenteritis 显示文摘 | Schwartz DA Pardi DS Murray JA | 2001 | Dig Dis Sci2001，46，： | 1 |
| 13 | Recovery after unilateral phrenicinjury associated with coronary artery revascularization显示文摘 | Wilcox PG Pare PD? Pardy RL | 1990 | Chest1990，98，3： | 1 |
| 14 | T lymphocytes 显示文摘 | Fabbri M Smart C Pardi R | 2003 | Int J Biochem Cell Biol2003，35，7： | 1 |
| 15 | Evolution of the Kdo2-lipid A biosynthesis in bacteria显示文摘 | Opiyo SO Pardy RL Moriyama H Moriyama EN | | 0，，： | 1 |
| 16 | Review article: microscopic colitis lympho- cytic, collagenous and mast cell colitis显示文摘 | Yen E F Pardi D S | 2011 | Aliment Phannacol T- her2011，34，1： | 1 |
| 17 | Paraneoplastic dysmotili- ty: loss of interstitial cells of Cajal 显示文摘 | Pardi DS Miller SM Miller DL | 2002 | Am J Gastroenterol2002，97，7： | 1 |
| 18 | Role of a heterogeneous free state in the formation of a specific RNA-theophylline complex显示文摘 | Jucker F M Phillips R M McCaUum S A Pardi A | 2003 | Biochem2003，42，： | 1 |
| 19 | Small-bowel imaging in Crohn’s disease: a prospective, blinded, 4-way comparison trial显示文摘 | Craig A. Solem Edward V. Loftus Joel G. Fletcher Todd H. Baron Christopher J. Gostout Bret T. Petersen William J. Tremaine Laurence J. Egan William A. Faubion Kenneth W. Schroeder Darrell S. Pardi Karen A. Hanson Debra A. Jewell John M. Barlow Jeff L. Fid | 2008 | Gastrointestinal Endoscopy2008，，2： | 1 |
| 20 | Expression and channel properties of a-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid neurons显示文摘 | McNemey ME Pardi D Pugh PC | 2000 | J Neurophysiol2000，84，3： | 1 |
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