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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | 透析前后血压水平与全因死亡风险的关系:一项剂量-效应关系的荟萃分析显示文摘血液透析人群的血压管理是一个巨大挑战。该研究旨在通过剂量-效应关系的荟萃分析,评估血液透析人群中透析前后血压水平与全因死亡风险之间关联的定量特征和潜在阈值。研究人员搜索了2017年3月18日之前发表的、关于透析前后血压水平与全因死亡率风险关联的所有前瞻性队列研究资料,共纳入来自8项研究的229688例普通血液透析患者。 | 刘莉 叶鹏 Han YC Tu Y Zhou LT Pan MM Wang B Liu H Tang RN Liu BC | 2018 | 中华高血压杂志2018，26，11： | 2 |
| 3 | The role of growth factors in the pathogcnesis of diaetic retinopathy显示文摘 | Grant MB Afzal A Spoerri P Pan H Shaw LC Mames RN | 2004 | Exp Opin Invest Drugs2004，13，10： | 1 |
| 4 | Bacteriophage lyric patterns for identification of salmonellae, shigeUae, Escherichia coli, Citrobacter freundii, and Enterobacter cloacae显示文摘 | He XQ Pan RN | 1992 | J Clin Microbiol1992，30，： | 1 |
| 5 | The role of growth factors in the pathogenesis of diabetic retinopathy显示文摘 | Grant MB Afzal A Spoerri P Pan H Shaw LC Mames RN | 2004 | Expert Opin Invest Drugs2004，13，10： | 1 |
| 6 | Golgi-situated endoplasmic reticulum alpha-1,2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with gamma-COP显示文摘 | Pan S Cheng X Sifers RN | 2013 | Mol Biol Cell2013，24，8： | 1 |
| 7 | Bacteriophage lytic panems for identification of salmonellae, shigeUae, Escherichia coli, Citrobacter freundii, and Enterobacter cloacae显示文摘 | He XQ and Pan RN | 1992 | J Clin Microbiol1992，30，： | 1 |
| 8 | The role of growth factors in the pathogenesis of diabetic retinopathy显示文摘 | Grant MB Afzal A Spoerri P Pan H Shaw LC Mames RN | 2004 | Exp Opin Invest Drugs2004，13，10： | 1 |
| 9 | The role of growth factors in the pathogenesis of diabetic retinopathy显示文摘 | Grant MB Afzal A Spoerri P Pan H Shaw LC Mame s RN | 2004 | Exp Opin Invest Drugs2004，13，10： | 1 |
| 10 | Enhancement of dissolution and bioavailability of piroxicam in solid dispersion systems显示文摘 | Pan RN Chen JH Chen RRL | 2000 | Drug Dev Ind Pharm2000，26，9： | 1 |
| 11 | Bacteriophage lytic patterns for identification of salmonellae,shigellae,Escherichia coli,Citrobacter freundii,and Enterobacter cloacae显示文摘 | He XQ Pan RN | 1992 | Journal of clinical microbiology1992，30，3： | 1 |
| 12 | Accelerated design of high-performance Mg-Mn-based magnesium alloys based on novel bayesian optimization显示文摘Magnesium(Mg),being the lightest structural metal,holds immense potential for widespread applications in various fields.The development of high-performance and cost-effective Mg alloys is crucial to further advancing their commercial utilization.With the rapid advancement of machine learning(ML)technology in recent years,the“data-driven''approach for alloy design has provided new perspectives and opportunities for enhancing the performance of Mg alloys.This paper introduces a novel regression-based Bayesian optimization active learning model(RBOALM)for the development of high-performance Mg-Mn-based wrought alloys.RBOALM employs active learning to automatically explore optimal alloy compositions and process parameters within predefined ranges,facilitating the discovery of superior alloy combinations.This model further integrates pre-established regression models as surrogate functions in Bayesian optimization,significantly enhancing the precision of the design process.Leveraging RBOALM,several new high-performance alloys have been successfully designed and prepared.Notably,after mechanical property testing of the designed alloys,the Mg-2.1Zn-2.0Mn-0.5Sn-0.1Ca alloy demonstrates exceptional mechanical properties,including an ultimate tensile strength of 406 MPa,a yield strength of 287 MPa,and a 23%fracture elongation.Furthermore,the Mg-2.7Mn-0.5Al-0.1Ca alloy exhibits an ultimate tensile strength of 211 MPa,coupled with a remarkable 41%fracture elongation. | Xiaoxi Mi Lili Dai Xuerui Jing Jia She Bjørn Holmedal Aitao Tang Fusheng Pan | 2024 | Journal of Magnesium and Alloys2024，12，2： | 0 |
| 13 | 新斯的明降低分娩期患者A控硬膜外镇痛(PCEA)的布比卡因用量:一项随机对照研究显示文摘背景鞘内注射新斯的明产生镇痛作用的同时可能导致重度恶心。相反,硬膜外注射新斯的明可以增强阿片类药物和局部麻醉药的镇痛作用而不产生恶心呕吐。以往的研究只针对单次硬膜外注射新斯的明,而对连续硬膜外注射新斯的明和母婴安全性未进行评估。因此,本研究拟验证在分娩期患者中新斯的明复合布比卡因硬膜外注射是否减少布比卡因用量。方法12例择期剖宫产的健康产妇随机分组,分别接受40μg(n=6)和80μg(n=6)新斯的明单次注射,监测20分钟胎心率(fetalheartrate,FHR)和宫缩。然后,另外40例健康的分娩期产妇随机分组,分别接受布比卡因1.25mg/ml或联合新斯的明4μg/ml产妇自控硬膜外镇痛(patient—controlledepiduralanalgesia,PCEA)。主要观察指标为每小时布比卡因用量。结果硬膜外新斯的明单次注射未导致FHR基础值改变,未诱导宫缩或产生恶心。硬膜外新斯的明的使用可使全部产妇的布比卡因用量减少19%,P〈0.05(使用4小时以上产妇用量减少达25%,P〈0.05),但可能导致轻度镇静。两组产妇的分娩方式、恶心发生率和FHR异常情况均相似。结论以上数据显示硬膜外使用新斯的明可降低PCEA中布比卡因每小时需要量的19%-25%。单次给药和连续注射新斯的明均不会诱发恶心、诱导宫缩或FHR异常,但可能导致轻度镇静。 | Vernon H. Ross, MD Peter H. Pan, MD Medge D. Owen, MD Melvin H. Seid, MD Lynne Harris, RN Brittany Clyne, MD Misa Voltaire, MD James C. Eisenach, MD 房丽丽(译) | 2011 | 麻醉与镇痛2011，7，5： | 0 |
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