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| 1 | 乳汁免疫和猪流行性腹泻病毒病疫苗:历史和现状(译文)显示文摘由于肠道病毒感染导致仔猪在发病率、死亡率和生产能力丧失方面的影响,每年给养猪者带来数百万美元的损失。2013—2014年间,猪流行性腹泻病毒(PEDV)病的暴发给美国养猪业带来了9亿~18亿美元的经济损失。被动乳汁免疫被认为是保护新生哺乳仔猪免受PED等肠道疾病危害的最有希望和有效的方法。通过乳汁免疫被动保护哺乳仔猪的效果依赖于病原特异性IgA浆细胞转运至乳腺的数量和乳汁中分泌型IgA的积累程度,这种免疫途径被定义为'肠-乳腺-sIgA轴'。由于胎盘的不可穿透性,新生仔猪处于无免疫球蛋白的状态,对很多的传染性病原体极易感。它们仅依靠来源于母源的初乳和乳汁抗体获得被动保护。先前开发的关于猪传染性胃肠炎病毒(TGEV)病的活疫苗和灭活疫苗,提供了对母源性免疫和仔猪被动保护机制的理解。在这篇文章中,综述了猪传染性胃肠炎病毒诱导乳汁免疫的研究进展,并指出对当前养猪业正努力控制的猪流行性腹泻病毒感染和相关疫苗的研究方向。同时研究和鉴别出影响乳汁免疫和'肠-乳腺-sIgA轴'的各种因素,有助于改善妊娠母猪预防猪流行性腹泻病毒感染以及改进其它肠道病原用疫苗方案,从而达到提升整个猪群的免疫力、猪群健康和企业生产力的目的。 | Langel Stephanie N Paim Francine Chimelo Lager Kelly M Vlasova Anastasia N Saif Linda J 吕茂杰 | 2017 | 养猪2017，，1： | 3 |
| 2 | Inhibition of Macrophage Oxidative Stress Prevents the Reduction of ABCA-1 Transporter Induced by Advanced Glycated Albumin显示文摘 | Raphael Souza Pinto Gabriela Castilho Bruno Paim Adriana Machado-Lima Natalia Inada Edna Nakandakare Aníbal Vercesi Marisa Passarelli | 2012 | Lipids2012，，5： | 1 |
| 3 | Renal involvement in Henoch- Schonlein purpura: a multivariate analysis of initial prognostic factors 显示文摘 | de Almeida JL Campos LM Paim LB | 2007 | J Pediatr2007，83，3： | 1 |
| 4 | Renal Involvement in He- noch-Sehonlein Purpura: a Multivariate Analysis of Initial Prognostic Factors 显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | J Pediatr ( Rio J)2007，83，3： | 1 |
| 5 | Renal involvement inHenoch-Schonlein purpura:a mulitivariate analysis of initial prog-nostic factors显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | J Pediatr(RioJ)2007，83，3： | 1 |
| 6 | Isolation of a Sex Pheromone Receptor in Males of the Eastern Spruce Bud- worm, Choristoneura Fumiferana (Clem), (Lepidoptera: Tortricidae) 显示文摘 | ALBERT P J SEABROOK W D PAIM U | 1974 | J Corn Physiol1974，91，1： | 1 |
| 7 | Analysis of bursttests and long-term hydrostatic tests in produced water pipelines显示文摘 | da Costa Mattos H S Paim L M Reis J M L | 2012 | Engineering Failure Analysis2012，22，： | 1 |
| 8 | Characterization of fungal melanins and soil humic acids by chemical analysis and infrared spectroscopy显示文摘 | Paim S Linhares L F Magrich A S | 1990 | Biology and Fertility of Soils1990，10，： | 1 |
| 9 | Renal involvement in Henoch-Schonlein purpura:A multivariate analysis of initial prognostic factors显示文摘 | de Almeida JL Campos LM Paim LB | 2007 | J Pediatr2007，83，3： | 1 |
| 10 | Renal involvement in Henoch - Schonlein pur- pura:a multivariate analysis of initial prognos- tic factors 显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | J Pediatr ( RioJ )2007，83，3： | 1 |
| 11 | Renal involvement in Henoch-Schonlein purpura:a multivari- ate analysis of intial prognostic factors 显示文摘 | de Almeida JL Campos LM Paim LB Leone C Koch VH Silva CA | 2007 | J Pediatr ( Rio J )2007，83，3： | 1 |
| 12 | Renal involvement in Henoch-Sch-nlein purpura:a multivariate analysis of initial prognostic factors显示文摘 | de Almeida JL Campos LM Paim LB | 2007 | J Pediatr2007，83，3： | 1 |
| 13 | Renal involve-ment in Henoch-Schonlein purpura: a multivariate analysis ofinitial prognostic factors显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | J Pediatr2007，83，： | 1 |
| 14 | Immunohistochemical expression of p53,MDM2,Ki-67 and PCNA in central giant cell tumor显示文摘 | de Souza PE Paim JF Carvalhais JN | 1999 | J Oral Pathol Med1999，28，： | 1 |
| 15 | Renal involvement in Henoch-Sehonlein purpura: a multivariate analysis of initial prognostic factors显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | J Pediatr Rio2007，83，： | 1 |
| 16 | Renal involvement in Henoch-Schonlein purpura: a multivariate analysis of initial prognostic factors显示文摘 | Almeida JL Campos LM Paim LB | 2004 | Pediatr2004，，83： | 1 |
| 17 | Renal involvement in Henoch-Sch nlein purpura:a multivariate analysis of initial prognostic factors显示文摘 | Almeida JL Campos 1M Paim LB | 2007 | J Pediatr(Rio J)2007，83，3： | 1 |
| 18 | Using Ms-visual stu- dio and Arduino to do temperature measurements显示文摘 | LORSCHEITER Aguirre T PAIM | 2011 | Periodi- co Tche Quimica2011，8，16： | 1 |
| 19 | Renal invol- vement in Henoch-Schonlein purpura:a multivariate analysis of initial prognostic factors显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | Jornal De Pediatria2007，83，3： | 1 |
| 20 | Renal involvement in henoch-schonlein purpura: a multivariate analysis of initial prognostic factors 显示文摘 | Almeida J L Campos L M Paim L B | 2007 | J Pediatr2007，83，3： | 1 |
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