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| 1 | Pulmonary fibrosis and emphysema: Is the emphysema type associated with the pattern of fibrosis?显示文摘AIM: To investigate whether the predominant emphysema type is associated with the high resolution computed tomography(HRCT) pattern of fibrosis in combined pulmonary fibrosis and emphysema(CPFE).METHODS: Fifty-three smokers with upper lobe emphysema and lower lobe pulmonary fibrosis on- HRCT-were retrospectively evaluated. Patients were stratified into 3 groups according to the predominant type of emphysema: Centrilobular(CLE), paraseptal(PSE), CLE = PSE. Patients were also stratified into 3 other groups according to the predominant type of fibrosis on HRCT: Typical usual interstitial pneumonia(UIP), probable UIP and nonspecific interstitial pneumonia(NSIP). HRCTs were scored at 5 predetermined levels for the coarseness of fibrosis(Coarseness), extent of emphysema(emphysema), extent of interstitial lung disease(Tot Ext ILD), extent of reticular pattern not otherwise specified(Ret NOS), extent of ground glass opacity with traction bronchiectasis(extG GOBx), extent of pure ground glass opacity and extent of honeycombing. HRCT mean scores, pulmonary function tests, diffusion capacity(DLCO) and systolic pulmonary arterial pressure were compared among the groups.RESULTS: The predominant type of emphysema was strongly correlated with the predominant type of fibrosis. The centrilobular emphysema group exhibited a significantly higher extent of emphysema(P < 0.001) and a lower extent of interstitial lung disease(P < 0.002), reticular pattern not otherwise specified(P < 0.023), extent of ground glass opacity with traction bronchiectasis(P < 0.002), extent of honeycombing(P < 0.001) and coarseness of fibrosis(P < 0.001) than the paraseptal group. The NSIP group exhibited a significantly higher extent of emphysema(P < 0.05), total lung capacity(P < 0.01) and diffusion capacity(DLCO)(P < 0.05) than the typical UIP group. The typical UIP group exhibited a significantly higher extent of interstitial lung disease, extent of reticular pattern not otherwise specified, extent of ground glass opacity with traction bronchiectasis, extent of honeycombing and coarseness of fibrosis(0.039 > P > 0.000). Although the pulmonary arterial pressure was higher in typical UIP group relative to the NSIP group, the difference was not statistically significant.CONCLUSION: In CPFE patients, paraseptal emphysema is associated more with UIP-HRCT pattern and higher extent of fibrosis than centrilobular emphysema. | Anastasia Oikonomou Paraskevi Mintzopoulou Argyris Tzouvelekis Petros Zezos George Zacharis Anastasios Koutsopoulos Demosthenes Bouros Panos Prassopoulos | 2015 | World Journal of Radiology2015，7，9： | 2 |
| 2 | Development of virtual CT cholangiopancreatoscopy显示文摘 | Prassopoulos P Raptopoulos V Chuttani R | 1998 | Radiology1998，209，2： | 1 |
| 3 | The thickness of the renal parenchyma decreases with age: a CT study of 360 patients 显示文摘 | GOURTSOYIANNIS N PRASSOPOULOS P CAVOURAS D | 1990 | AJR Am J Roent genol1990，155，3： | 1 |
| 4 | CT Evaluation of Mesenteric Panniculitis:Prevalence and Associated Diseases显示文摘 | Daskalogiannaki M Voloudaki A Prassopoulos P | 2000 | AJR2000，174，2： | 1 |
| 5 | A study of the variation of colonic positioning in the pararenal space as shown by computed tomography显示文摘 | Prassopoulos P Gourtsoyiannis N Cavouras D | 1990 | Eur Radiol1990，10，1： | 1 |
| 6 | Assessment of myocardialadrenergicinnervationin patients with sicksinussyndrome: Effect of asynchronousventricularactivation from ventricularapical- stimulation显示文摘 | Marketou ME Simantirakis EN Prassopoulos VK | 2002 | Heart2002，88，： | 1 |
| 7 | Contrast-Enhanced Magnetic Resonance Cholangiography Versus Heavily T2-Weighted Magnetic Resonance Cholangiography显示文摘 | NICKOLAS PAPANIKOLAOU PANOS PRASSOPOULOS ELENI ERACLEOUS THOMAS MARIS CHRISTOS GOGAS NICHOLAS GOURTSOYIANNIS | 2001 | Investigative Radiology2001，，11： | 1 |
| 8 | Maturation of the Tract After Percutaneous Cholecystostomy with Regard to the Access Route显示文摘 | Adam A. Hatjidakis Spyros Karampekios Panos Prassopoulos Evaghelos Xynos Maria Raissaki Sophocles I. Vasilakis Nicholas C. Gourtsoyiannis | 1998 | Cardiovascular and Interventional Radiology1998，，： | 1 |
| 9 | MR enteroclysis imaging of Crohn disease 显示文摘 | PRASSOPOULOS P PAPANIKOLAOU N GRAMMATIKAKIS J | 2001 | Radiographics2001，21，10： | 1 |
| 10 | Relation of cardiac sympathetic innervation to proinflammatory cytokine levels in patients with heart failure secondary to indopathic dilated cardiomyopathy显示文摘 | Parthenakis FI Patrianakos A Prassopoulos V | 2003 | American Journal of Cardiology2003，91，10： | 1 |
| 11 | Determination of normal splenic volume on computed tomography in relation to age,gender and body habitus显示文摘 | Daskalogiannaki M Raissaki M | 1997 | Eur Radiol1997，7，2： | 1 |
| 12 | CT evaluation of mesenteric panniculitis:prevalence andassociated diseases显示文摘 | Daskalogiannaki M Voloudaki A Prassopoulos P | | 0，，： | 1 |
| 13 | Sacroiliac Joints, anatomical variants on CT 显示文摘 | Prassopoulos PK Faflia CP voloudaki AE | 1999 | J Comput Assist Tomogr1999，23，2： | 1 |
| 14 | Contrast-enhanced magnetic resonance cholangiography versus heavily T2-weighted magnetic resonance cholangiography显示文摘 | Papanikolaou N Prassopoulos P Eracleous E | 2001 | Invest Radiol2001，36，11： | 1 |
| 15 | Acute cholecystitis in high-risk patients:percutaneous cholecystostomy vs conservative treatment显示文摘 | Hatzidakis AA Prassopoulos P Petinarakis I | 2002 | Eur Radiol2002，12，： | 1 |
| 16 | MR and CT features in two unusual cases of xanthogranulomatous pyelonephritis显示文摘 | Anezinis P Prassopoulos P Daskalopoulos G | 1998 | Eur J Radiol1998，28，1： | 1 |
| 17 | Conceptus radiation dose and risk from chest screen-film radiography显示文摘 | Darrglakis J Perisinakis K Prassopoulos P | 2003 | Eur Radiol2003，13，2： | 1 |
| 18 | MR enteroclysis: technical considerations and clinical applications显示文摘 | Nicholas Gourtsoyiannis Nickolas Papanikolaou John Grammatikakis Panos Prassopoulos | 2002 | European Radiology2002，，11： | 1 |
| 19 | Malignant peritoneal mesothelioma presenting with respiratory symptoms显示文摘 | Daskalogiannaki M Prassopoulos P Raissaki M | | 0，，05： | 1 |
| 20 | Aggressive lepto-meningeal hemangioblastomatosis of the central nervous system in a patient with von Hippel-Iindau disease显示文摘 | Courcoutsakis NA Prassopoulos PK Patronas NJ | 2009 | AJNR Am J Neuroradi-ol2009，30，4： | 1 |
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