维普中文期刊产品整合服务
7060篇 您的检索式:作者名="PENG S"
    题名 作者 年代 出处 被引量
1放顶煤液压支架承载特性及其适应性分析显示文摘通过对两柱、四柱式放顶煤液压支架支架结构特征分析,研究了不同工作阻力两柱式放顶煤液压支架、相同工作阻力两柱和四柱式放顶煤液压支架承载特性和其影响因素,并对液压支架适应性进行分析。研究结果表明:液压支架的结构特性决定其承载特性,两柱式放顶煤液压支架平衡千斤顶机构决定其有效承载范围在顶梁柱窝附近,增大立柱和平衡千斤顶的工作阻力能增大其承载能力,但通过增大平衡千斤顶工作阻力改变支架承载能力有限;四柱式放顶煤液压支架两排立柱与顶梁铰接位置决定其有效承载范围与立柱排距相当,增大前柱工作阻力降低后柱工作阻力能提高支架顶梁前段支撑能力,使支架有效承载范围前移;液压支架承载特性决定其适应性。平衡千斤顶能适时调节两柱式放顶煤液压支架顶梁上顶板荷载作用的位置,使其能适应一般综放工作面,但特厚煤层大采高综放工作面顶板荷载受顶煤放出影响作用位置多变,易导致平衡千斤顶损坏,四柱式支架有效承载范围较宽,使其能适应特厚煤层大采高综放工作面。李化敏 蒋东杰 Syd S Peng 冯军发 2015煤炭科学技术2015,43,6:33
2基于海量矿压监测数据的采场支架与顶板状态智能感知技术显示文摘超前感知综采工作面顶板来压并预判冒顶事故、自主评价支护参数的适应性,是提高综采工作面安全高效及智能化水平的基础。围绕综采工作面支架与顶板状态智能感知的核心问题,基于综采工作面电液控制液压支架海量监测数据,开发了综采工作面支架与顶板状态智能感知系统(SSRI);结合大数据挖掘及工作循环分析技术,提出了用于支架压力分析的多因次工作循环特征参数;研究了安全阀开启、割煤及邻架移架、地质等多种因素影响下的单台支架承载特征及支架群组载荷转移分布规律;在深入解读支架阻力及活柱下缩时序曲线所蕴含的支架与围岩相互作用关系的基础上,构建了支架与顶板状态智能感知模型,实现了对顶板来压的预测、冒顶预警、支架适应性及支护质量评价,初步建立了基于海量矿压监测数据的采场支架与顶板状态智能感知技术体系。结果表明:①额定工作阻力不应作为评价支架承载能力的惟一或主要指标,初撑力、额定工作阻力及安全阀开启特性等参数共同决定了支架的承载特性及承载能力;②充分挖掘分析海量矿压监测数据,可以实现采场顶板灾害智能预警、支护质量评价及故障诊断等研究目标;③对海量监测数据的深入分析与利用是实现综采工作面支架围岩耦合自适应控制、支护参数自适应调整等智能化开采目标的前提与基础。程敬义 万志军 PENG Syd S 张洪伟 邢轲轲 闫万梓 刘泗斐 2020煤炭学报2020,45,6:17
3美国煤炭地下开采与自动化技术进展显示文摘美国煤炭的地下开采分为长壁式和房柱式2种技术。地质条件较好、井田范围大的矿井,一般以长壁开采为主,否则以房柱开采为主。1994—2017年,美国井工矿数量减少了79%(2017年为237座)。但是单个矿井产量增加了230%,煤炭生产更加集中、高效。美国长壁开采以中厚煤层为主,采高一般为1.6~2.5 m(最大开采高度4.2 m,最小开采高度1.2 m)。长壁工作面均采用多巷布置、矩形断面巷道、锚杆支护。近年来,工作面尺寸、设备功率、设备尺寸逐渐增大,生产系统更加可靠。长壁工作面的自动化开采源于1984年的电动控制液压支架的研发与使用,此后开发了支架、采煤机、刮板输送机的单机自动化以及追机移架技术。2000年以后开发了半自动化工作面技术和采煤机远程控制技术。目前应用的主要是半自动化工作面技术,只有2个工作面应用了采煤机远程控制技术。这些技术解决了条件简单工作面的自动化开采问题,但遇到复杂地质条件时,仍需要人工干预。研发自动化开采的关键传感器和设备以适应地质条件变化、完善端部进刀系统,聚焦作业安全和粉尘与噪音防控,以及矿用大数据、高速通信与可视化技术是目前美国的重要研发方向。在近10 a来,房柱开采的工艺变化不大,但是开采装备的多样化和开采系统的自动化、信息化、智能化的相关技术开发取得了重要进展。王家臣 PENG Syd S 李杨 2021煤炭学报2021,46,1:16
4Relationship between Fas/ FasL expression and apoptosis of colon adenocarcinoma cell lines显示文摘INTRODUCTIONFas/ FasL system has been identified as a keymediator of apoptosis in tumor cells[1-4]. Theoccurrence and development of neoplasm are closelyrelated to apoptosis[5-7] Most chemotherapeuticdrugs kill cancer cells mainly by inducingapoptosis[8-14].'Zhi Hai Peng Tong Hai Xing Guo Qiang Qiu Hua Mei Tang Shanghai No. 1 People’s Hospital, Shanghai 200080, China 2001World Journal of Gastroenterology2001,7,1:15
5The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment.ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart 2019Science China(Physics,Mechanics & Astronomy)2019,62,2:11
6神东矿区岩石物理力学性质变化规律研究显示文摘通过对神东矿区3个典型大采高工作面钻孔柱状岩石物理力学性质与沉积时期和埋深关系的研究,得到如下结论:1)埋深相同的同类岩性岩石的物理力学性质与沉积时期有着密切联系,同矿区不同矿井同一岩性即使在同一埋深条件下,其岩石物理力学性质也有很大的不同,沉积时期早的岩石物理力学性质大于沉积时期晚的岩石;2)同类岩性岩石的物理力学参数总体上随着埋深的增加而增加,且大多数岩石的物理力学性质与埋深具有较好的线性关系;3)同一矿井的砂岩类抗压强度和抗拉强度与颗粒粒径成反比,且泥岩类的抗压强度和抗拉强度普遍比粗砂岩和含砾粗砂岩高。杜锋 Syd S PENG 2019采矿与安全工程学报2019,0,5:10
7The results and prognosis of different treatment modalities for solitary metastatic lung tumor from nasopharyngeal carcinoma:a retrospective study of 105 cases显示文摘Background and Objective:Nasopharyngeal carcinoma (NPC) is known for its propensity for distant metastases.Lung metastasis is one of the most important causes of death for patients with NPC.Solitary metastatic lung tumor from NPC is a distinctive group associated with a better survival.This study was to find a more effective treatment modality and prognostic factors for the group.Methods:Clinical data of 105 cases of solitary metastatic lung tumor from NPC were retrospectively analyzed.Survival rate was calculated by the Kaplan-Meier method.The difference of survival between the patients treated by different modalities was evaluated by the log-rank test.The Cox univariate and multivariate analyses of gender, age, pathologic type, stage, adjuvant chemotherapy, evaluation of treatment for NPC, disease-free interval, size of metastatic tumor, pulmonary hilar and/or mediastinal lymph node metastasis, treatment modalities, recurrent distant metastases and/or relapse of NPC were conducted.Results:The local control rate was 53.8% in chemotherapy group, 88.0% in radiotherapy +/-chemotherapy group, and 96.4% in operation +/-chemotherapy group (P<0.01).The most promising progression-free survival (PFS) and overall survival (OS) were obtained with operation +/-chemotherapy and followed by radiotherapy +/-chemotherapy.Both of them showed much better efficacy than chemotherapy (P<0.001).The Cox multivariate analysis showed that recurrent distant metastases and/or relapse of NPC affected the survival (OR=2.087, 95% CI=1.277-3.410, P=0.003).The T stage of NPC, size of metastatic tumor, hilar and/or mediastinal lymph node metastasis, and the treatment modality were independent prognostic factors.Conclusions:Operation +/-chemotherapy and radiotherapy +/-chemotherapy are better treatment of solitary metastatic lung tumor from NPC, which could improve the local control and prolong the PFS and OS.Chemotherapy is recommended for patients with higher T stage of NPC, size of metastatic tumor ≥3 cm, pulmonary hilar and/or mediastinal lymph node metastasis.Jun Ma1,2, Zhe-Sheng Wen1,2, Peng Lin1,2, Xin Wang1,2, Fang-Yun Xie1,3 1 State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P.R.China 2 Department of Thoracic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R.China 3 Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R.China Department of Thoracic Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi 030012, P.R.China 2010Chinese Journal of Cancer2010,29,9:9
8Effects of 5-hydroxytamine and its antagonists on hepatic stellate cells显示文摘BACKGROUND: Hepatic stellate cell (HSC) plays a key role in hepatic fibrosis. This study was undertaken to investigate the expression of 5-hydroxytamine receptors in HSC and the effect of 5-hydroxytamine on biological characteristics of HSC. METHODS: Liver ex vivo perfusion of collagenase and density gradient centrifugation were used to isolate HSCs. Reverse transcriptase polymerase chain reaction (RT-PCR) was used to detect the expression of 5-hydroxytamine receptor subtypes 1A, 2A, 2B and 3. Western blot hybridization was used to elucidate the effect of 5-hydroxytamine and its 2A receptor antagonist ketanserin and 3 receptor antagonist ondanosetron on the expression of transforming growth factor-β1(TGF-β1) and Smad4 in HSC. RESULTS: HSC expressed 5-hydroxytamine receptor subtypes 1A, 2A and 2B. 5-hydroxytamine significantly increased the expression of TGF-β1, and Smad4 in HSC (P<0.05). This action can be antagonized by ketanserin, not by ondanosetron. CONCLUSIONS: HSC expresses 5-hydroxytamine receptors. 5-hydroxytamine could effect the biological characteristics of HSC through its receptor mediation, and may play a role in the pathogenesis of liver cirrhosis and portal hypertension.Tao Li, Shan-Geng Weng, Xi-Sheng Leng, Ji-Run Peng, Yu-Hua Wei, Dong-Cheng Mou and Wan-Xiang Wang Department of Hepatobiliary Surgery, Peking University People’s Hospital, Beijing 100044, China 2006Hepatobiliary & Pancreatic Diseases International2006,5,1:7
9Tensile properties and fracture behavior of Ti_2AlNb based alloys at room temperature显示文摘The tensile mechanical properties and fracture behaviors of Ti 22Al 20Nb 7Ta alloys were studied at room temperature. Three typical microstructures of Ti 2AlNb based alloys were obtained by combination of thermal mechanical processing and heat treat ment. They are: 1) lath mixture of O + B 2 with remaining β grain boundaries and α 2 phase; 2) equiaxed O phase in B 2 matrix; 3) fine lath mixture of O + B 2 without remaining β grain boundaries. It is shown that the microstructure obviously affects the tensile properties of Ti 2AlNb based alloys. The microstructure of fine lath mixture of O + B 2 without remaining β grain boundaries has good combination of yield stress and ductility, while the microstructure with lath mixture of O + B 2 with remaining β grain boundaries and α 2 phase has low yield stress and elongation. The fracture mode was also controlled by the microstructure of Ti 2AlNb based alloys. By means of SEM, it was found that the dominated fracture mode of microstructure with lath mixture of O + B 2 with remained β grain boundary and α 2 phase was intergranular, and the fracture mode of the other two microstructures was mainly transgranular.PENG Ji hua(彭继华) 1, 2 , MAO Yong(毛 勇) 2, LI Shi qiong(李世琼) 2, SUN Xun fang(孙训方) 2 1. Department of Engineering Mechanics, Southwest Jiaotong University, Chengdu 610031, P.R.China 2. Division of Super Alloys, Central Iron and S 2000中国有色金属学会会刊:英文版2000,10,3:6
10Orthogonal design for optimization of pigment extraction from surface sediments of the Changjiang River Estuary显示文摘Using a suitable solvent for extracting pigments from sediment for high performance liquid chromatography(HPLC) analysis is critical for obtaining qualitative and quantitative estimates of phytoplanktonic and benthic algal biomass,as well as community composition. Five methodological factors(sample dehydration,extraction solvent,extraction duration,number of extractions,and ratio of solvent volume:sample weight) were studied using an L 9(3 4 ) orthogonal design in a sedimentary pigment extraction experiment on samples collected from the Changjiang large-river delta-front estuary(LDE),using HPLC analysis. The results show that the optimal extraction method for sedimentary pigments should include freeze-drying samples prior to extraction. The effects of different factors on sedimentary pigment extraction were separated by the L 9(3 4 ) orthogonal design experiments and showed that the extraction solvent was the most important,with extraction duration the second most important,and numbers of extraction and ratio of solvent volume:sample weight was the least important. The mixed solvent treatment comprised of acetone,methanol and water(80:15:5,by volume) was best for polar pigment extraction,with 100% acetone better for apolar pigments. For most pigments employed in this study(i.e.,peridinin,fucoxanthin,alloxanthin,diatoxanthin,zeaxanthin,pheophytin-a and β-carotene) ,3 h was found to be enough time for extraction from these deltaic sediments. However,for chlorophyll-a,the most important pigment used for estimating algal biomass,12 h was needed. A small amount of solvent(3 ml) with duplicate extractions obtained the greatest amount and diversity of pigments. Unfortunately,no extraction method was found to be suitable for all pigments in sediments. The choice of extraction procedure should be made in accordance with the objective of each study,taking into consideration the properties of sediments and pigments in question.ZHAO Jun YAO Peng YU Zhigang Thomas S Bianchi 2011Acta Oceanologica Sinica2011,30,4:6
11Surgical treatment for Nevin stage IV and V gallbladder carcinoma: report of 70 cases显示文摘BACKGROUND: The role of aggressive surgery for end-stage gallbladder carcinoma is controversial. This retrospective study was designed to evaluate the outcome of surgical treatment for Nevin stage Ⅳ and Ⅴ gallbladder carcinoma at a single institution. METHODS: A retrospective analysis was made on 70 patients with Nevin stage Ⅳ and Ⅴ gallbladder carcinoma undergoing surgical treatment from January 1993 to June 2004. RESULTS: There were 22 cases of stage Ⅳ and 48 of stage V. Cholecystectomy was performed in 37 cases with a resection rate of 53%,9 cases received radical resection, 13 extended radical resection, and 15 palliative resection. The curative resection rate was 31% and the morbidity rate was 36%. Postoperative 1-, 3-, 5-year survival rates of curative and palliative resection were 69%, 33%, 8% and 27%, 13%, 0, respectⅣely (P <0.01). The 1- and 3-year survival rates of patients undergoing exploratory laparotomy only were 3% and 0, respectively. CONCLUSIONS: Nevin stage Ⅳ and Ⅴ gallbladder carcinoma should be treated by aggressive surgery. Curative resection is promising in the improvement of long-term survⅣal rate.Wei-Dong Xiao,Cheng-Hong Peng,Guang-Wen Zhou,Wei-Ding Wu, Bo-Yong Shen, Ji-Qi Yan,Wei-Ping Yang and Hong-Wei Li Department of Surgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China First author’s present address: Deparment of General Surgery, the First Affiliated Hospital, Nanchang University, Nanchang 330006, China 2005Hepatobiliary & Pancreatic Diseases International2005,4,4:5
12Refinement of heterozygosity loss on chromosome 5p15 in sporadic colorectal cancer显示文摘AIM: To refine the loss of heterozygosity on chromosome 5p15 and to identify the new tumor suppressor gene (s) in colorectal tumorigenesis.METHODS: Sixteen polymorphic microsatellite markers were analyzed on chromosome 5 and another 6 markers were applied on chromosome 5p15 in 83 cases of colorectal and normal DNA by PCR. PCR products were electrophoresed on an ABI 377 DNA sequencer. Genescan 3.1 and Genotype 2.1 software were used for LOH scanning and analysis.RESULTS: We observed 2 distinct regions of frequent allelic deletions on Chromosome 5, at D5S416 on 5p15 and D5S428-D5S410 on 5q. Another 6 polymorphric microsatellite markers were applied to 5p15 and the minimal region of frequent loss of heterozygosity was established on 5p15spanning the D5S416 locus.CONCLUSION: Through our detailed deletion mapping studies, we have found a critical and precise location of 5p deletions, 5p15.2-5p15.3, which must contain one or more unknown tumor suppressor gene (s) of colorectal cancer.Shi-Feng Xu Zhi-Hai Peng Da-Peng Li Guo-Qiang Qiu Fang Zhang, Department of General Surgery, Shanghai First People’s Hospital, Shanghai 200080, China 2003World Journal of Gastroenterology2003,9,8:5
13Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial显示文摘Craig S Anderson Yining Huang Ji Guang Wang Hisatomi Arima Bruce Neal Bin Peng Emma Heeley Christian Skulina Mark W Parsons Jong Sung Kim Qing Ling Tao Yue Chun Li Jian Dong Jiang Li Wen Tai Jin Li Zhang En Xu Yan Cheng Stephane Heritier Lewis B Morgenste 2008Lancet Neurology2008,,5:4
14Pediatric Wilson disease presenting as acute liver failure:Prognostic indices显示文摘BACKGROUND Acute liver failure(ALF)can be a primary presentation of Wilson disease(WD).Mortality rates are high in WD with ALF(WDALF).Predictions of mortality in WDALF vary by model and are sometimes contradictory,perhaps because few patients are studied or WD diagnoses are questionable.AIM To determine the outcomes among well-documented WDALF patients and assess mortality model performance in this cohort.METHODS We reviewed the medical records of our pediatric WDALF patients(n=41 over 6-years-old,single-center retrospective study)and compared seven prognostic models(King’s College Hospital Criteria,model for end-stage liver disease/pediatric end-stage liver disease scoring systems,Liver Injury Unit[LIU]using prothrombin time[PT]or international normalized ratio[INR],admission LIU using PT or INR,and Devarbhavi model)with one another.RESULTS Among the 41 Han Chinese patients with ALF,WD was established by demonstrating ATP7B variants in 36.In 5 others,Kayser-Fleischer rings and Coombs-negative hemolytic anemia permitted diagnosis.Three died during hospitalization and three underwent liver transplantation(LT)within 1 mo of presentation and survived(7.3%each);35(85.4%)survived without LT when given enteral D-penicillamine and zinc-salt therapy with or without urgent plasmapheresis.Parameters significantly correlated with mortality included encephalopathy,coagulopathy,and gamma-glutamyl transpeptidase activity,bilirubin,ammonia,and serum sodium levels.Area under the receiver operating curves varied among seven prognostic models from 0.981 to 0.748 with positive predictive values from 0.214 to 0.429.CONCLUSION WDALF children can survive and recover without LT when given D-penicillamine and Zn with or without plasmapheresis,even after enlisting for LT.Wei-Yuan Fang Kuerbanjiang Abuduxikuer Peng Shi Yi-Ling Qiu Jing Zhao Yu-Chuan Li Xue-Yuan Zhang Neng-Li Wang Xin-Bao Xie Yi Lu A S Knisely Jian-She Wang 2021World Journal of Clinical Cases2021,9,14:4
15The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs.Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou 2023Horticulture Research2023,10,5:3
16Effectiveness of intravenous r- tPA versus UK for acute ischaemic stroke: a nationwide prospective Chinese registry study显示文摘Background Intravenous recombinant tissue plasminogen activator(r-tPA)and urokinase(UK)are both recommended for the treatment of acute ischaemic stroke(AIS)in China,but with few comparative outcome data being available.We aimed to compare the outcomes of these two thrombolytic agents for the treatment of patients within 4.5 hours of onset of AIS in routine clinical practice in China.Methods A pre-planned,prospective,nationwide,multicentre,real-world registry of consecutive patients with AIS(age≥18 years)who received r-tPA or UK within 4.5 hours of symptom onset according to local decision-making and guideline recommendations during 2017-2019.The primary effectiveness outcome was the proportion of patients with an excellent functional outcome(defined by modified Rankin scale scores 0 to 1)at 90 days.The key safety endpoint was symptomatic intracranial haemorrhage according to standard definitions.Multivariable logistic regression was used for comparative analysis,with adjustment according to propensity scores to ensure balance in baseline characteristics.Results Overall,4130 patients with AIS were registered but 320 had incomplete or missing data,leaving 3810 with available data for analysis of whom 2666 received r-tPA(median dose 0.88(IQR 0.78-0.90)mg/kg)and 1144 received UK(1.71(1.43-2.00)×104 international unit per kilogram).There were several significant intergroup differences in patient characteristics:r-tPA patients were more educated,had less history of stroke,lower systolic blood pressure,greater neurological impairment and shorter treatment times from symptom onset than UK patients.However,in adjusted analysis,the frequency of excellent outcome(OR 1.18,95%CI 1.00 to 1.40,p=0.052)and symptomatic intracranial haemorrhage(OR 0.70,95%CI 0.33 to 1.47,p=0.344)were similar between groups.Conclusions UK may be as effective and carry a similar safety profile as r-tPA in treating mild to moderate AIS within guidelines in China.Registration http://gffzzd5593dd32ed44506huf56xb09bkpw6ppf.ffgz.tsg.suse.edu.cn identifier:NCT02854592.Xinhong Wang Xiaoqiu Li Yuming Xu Runhui Li Qingcheng Yang Yong Zhao Fengyun Wang Baoying Sheng Runqing Wang Shaoyuan Chen Lihua Wang Liying Shen Xiaowen Hou Yu Cui Duolao Wang Bin Peng Craig S Anderson Huisheng Chen On behalf of INTRECIS Investigators 2021Stroke & Vascular Neurology2021,6,4:2
17Low-temperature sintering and microwave dielectric properties of Ca(Li1/3 Nb2/3)O3-δ ceramics显示文摘Liu Peng Kim E S Yoon K H 2001Jpn Journal Application Physics2001,40,:2
18Microwave dielectric properties of low temperature sintering Ca O3-δ 显示文摘Liu Peng Ogawa H Kim E S 2004Journal of European Ceramic Society2004,24,:2
19The main projects and development status of noise forecasting and controlling on working face in coal mine显示文摘Noise from the machine on coal working face seriously influenced the miners' physical and mental health, and also, due to the noise, there may be a major hidden danger in safety from accidents as all safety warning signals may be masked by the noise. This paper summarized the features of mine environmental noise on working face, such as the variety of noise sources, the continuity of high intensity and slow attenuation in narrow space, etc.The main projects about noise forecasting and controlling on working face was emphatically expounded;the development status about mines machinery noise mechanism and environmental noise acoustic characteristics of space-time of these main research topics were also introduced.PENG You-duo GUO Ying-fu WU Li-tao LI Xin XIE Wei-hua Dhillon B S 2010Journal of Coal Science & Engineering(China)2010,16,2:2
20查看详情显示文摘Peng X G Guan S Q Chai X D 0,,:2
返回顶部 每页显示:
共353页 首页 上一页 第1页 下一页 末页 /353 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费