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| 1 | Seven Things We Think We Know about Auxin Transport显示文摘植物激素植物生长素的极的运输和最大值调整的局部性的植物生长素的建立胚胎的开发,干细胞维护,根和射击建筑学,和回归线生长回答。过去的十年被戏剧的进步在阐明的努力标记植物生长素运输由调整的复杂机制种生长。作为植物生长素的理解,运输规定逐渐地被详细描述,这个过程在某些方面涉及几乎所有植物生长和环境回答,变得清楚。然而,我们仍然关于这基本规章的机制的一些基本方面缺乏信息。在这评论,我们在场我们知道什么(或我们认为什么我们知道) 并且我们什么不知道大约七个调整植物生长素的过程。我们在主要、侧面的根,向光性,分叉的射击,叶扩大,和脉络在 gravitropism 讨论植物生长素运输的角色。我们也在根尖端,植物生长素运输过程的 flavonoid 调整,和植物生长素 transporters 的 translational 以后规定的突出的方面讨论植物生长素倒流 / 喷泉模型。这讨论没打算彻底,但是加亮在哪个通常认为假设要求更真实的确认的区域。 | Wendy Ann Peer Joshua J. Blakeslee Haibing Yang Angus S. Murphy | 2011 | Molecular Plant2011，4，3： | 29 |
| 2 | NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene-induced colitis through down-regulation of NFκ-B and iNOS显示文摘AIM: To evaluate the efficacy and mechanism of action of NCB-02, a standardized Curcumin preparation, against 2, 4-dinitrochlorobenzene (DNCB)-induced ulcerative colitis in rats. METHODS: Ulcerative colitis was induced in male rats by sensitizing with topical application of DNCB in acetone for 14 d and intra-colonol challenge with DNCB on day 15. A separate group of animals with vehicle treatment in similar fashion served as control group. Colitis rats were divided into different groups and treated with NCB-02 at doses of 25, 50 and 100 mg/kg b.wt p.o. for 10 d. Sulfasalazine at a dose of 100 mg/kg b.wt for 10 d served as a reference group. On day 10 after respective assigned treatment, all the animals were euthanized and the length of the colon, weight of entire colon and distal 8 cm of the colon were recorded. The distal part of the colon was immediately observed under a stereomicroscope and the degree of damage was scored. Further distal 8 cm of the colon was subject to the determination of colonic myeloperoxidase (MPO), lipid peroxidation (LPO) and alkaline phosphatase (ALP) activities. A small piece of the sample from distal colon of each animal was fixed in 10% neutral buffered formalin and embedded in paraffin wax and sectioned for immunohistochemical examination of NFκ-B and iNOS expression. RESULTS: NCB-02 showed a dose dependent protection against DNCB-induced alteration in colon length and weight. NCB-02 treatment also showed a dose dependent protection against the elevated levels of MPO, LPO and ALP, induced by DNCB. NCB-02 demonstrated a significant effect at a dose of 100 mg/kg b.wt., which was almost equipotent to 100 mg/kg b.wt. of sulfasalazine. Treatment with sulfasalazine and curcuminat a dose of 100 mg/kg b.wt. inhibited the DNCB-induced overexpression of NFκ-B and iNOS in the colon. CONCLUSION: Curcumin treatment ameliorates colonic damage in DNCB-induced colitic rats, an effect associated with an improvement in intestinal oxidative stress and downregulation of colonic NFκ-B and iNOS expression. | MV Venkataranganna Md Rafiq S Gopumadhavan Ghouse Peer UV Babu SK Mitra | 2007 | World Journal of Gastroenterology2007，13，7： | 12 |
| 3 | 农杆菌介导一个内源HMG-box转录因子fvhom1转化金针菇显示文摘利用本实验室金针菇(Flammulina velutipes)基因组、转录组数据对一个内源HMG-box转录因子fvhom1进行了基因结构和表达量分析。通过根癌农杆菌介导转化的方法,以金针菇菌丝球为受体材料转入含该内源HMG-box转录因子的过表达载体,并获得了一个稳定的转化子。该转化子的潮霉素抗性筛选及潮霉素磷酸转移酶基因的PCR扩增结果均证明该过表达载体已整合到金针菇的基因组中。在无选择压力的的PDA固体培养基上继代培养培养5次后仍检测到潮霉素磷酸转移酶基因的存在,表明转入的质粒片段在转基因金针菇中稳定遗传。对该转化子菌丝生长速度测定结果表明,突变体的菌丝生长速度比野生型金针菇菌株显著变慢。实时荧光定量PCR结果表明,突变体中该转录因子表达量与野生型金针菇菌株相比显著上调了100倍左右。该转化子的获得为下一步深入研究金针菇HMG-box转录因子的功能提供了数据支持。 | 施乐乐 van Peer A.F. 郭丽 陈仁良 王威 严俊杰 邓优锦 谢宝贵 | 2014 | 基因组学与应用生物学2014，33，6： | 10 |
| 4 | 个体网络借贷(P2P)监管立法例及解读显示文摘央行会同其他部委发布的《关于促进互联网金融健康发展的指导意见》明确了'网络借贷业务由银监会负责监管'。十八届五中全会《关于制定国民经济和社会发展第十三个五年规划》要求'规范发展互联网金融'。银监会直面网络借贷(P2P)存在的诸多问题,如何有效地规范发展网络借贷(P2P)活动已经成为亟待解决的问题。规范发展网络借贷(P2P)应以保障投资者合法权益为主轴,以防范其风险发生与传染作为监管措施确立的出发点,以实现普惠金融作为目标,进而促进网络借贷(P2P)的健康持续发展与不断创新。个体网络借贷(P2P)监管立法在体现适度宽松监管政策,坚持适度监管、有效监管、创新监管等原则基础上满足上述要求,从而保障监管立法成为规范监管的善法。 | The Experts’ Suggestion of Rules of Peer to Peer Lending (P2P)Supervision Legislation bythe Expert’s Panel of Central University of Finance and Economics | 2016 | 财经法学2016，，1： | 6 |
| 5 | 萤光假单胞细菌根部定殖对水培系统中香石竹镰刀菌枯萎病的作用显示文摘本文报道萤光假单胞菌(fluorescent Pseudomas spp.)WCSX 13.WCS 417andWCS 358在水培系统中香石竹根部的定殖及其对香石竹镰刀菌枯萎病的抑制作用。细菌处理两周后,WCS 417在感病品种Lena和中抗品种Pallas根部的定殖分别为8.8×10~2cfu/cm和9.8×10~2cfu/cm,而WCS 358分别为0.9×10~2cfu/cm和0.13×10~2cfu/cm。在通气的三角瓶中水培的Pallas品种,人工接种病原菌香竹石尖镰孢Fusarium oxyspotum f.sp.dianthi(Prill.&Del.)Snyd.&Hans.(Fod)6周后,用WCSX·13和WCS 417根部处理的病指分别为0.19和0.31,未细菌处理的对照为0.58,细菌处理植株的根部及茎内组织的病原菌种群密度低于对照。营养膜技术(NFT)栽培的Lena品种,WCS 417细菌处理的发病率比对照减少13%。 | 徐同 R.van Peer H.Rattink B.Schippers | 1989 | 植物病理学报1989，19，3： | 6 |
| 6 | Haplotype-resolved genome assembly and allele- specific gene expression in cultivated ginger显示文摘Ginger(Zingiber officinale)is one of the most valued spice plants worldwide;it is prized for its culinary and folk medicinal applications and is therefore of high economic and cultural importance.Here,we present a haplotype-resolved,chromosome-scale assembly for diploid ginger anchored to 11 pseudochromosome pairs with a total length of 3.1 Gb.Remarkable structural variation was identified between haplotypes,and two inversions larger than 15Mb on chromosome 4 may be associated with ginger infertility.We performed a comprehensive,spatiotemporal,genome-wide analysis of allelic expression patterns,revealing that most alleles are coordinately expressed.The alleles that exhibited the largest differences in expression showed closer proximity to transposable elements,greater coding sequence divergence,more relaxed selection pressure,and more transcription factor binding site differences.We also predicted the transcription factors potentially regulating 6-gingerol biosynthesis.Our allele-aware assembly provides a powerful platform for future functional genomics,molecular breeding,and genome editing in ginger. | Shi-Ping Cheng Kai-Hua Jia Hui Liu Ren-Gang Zhang Zhi-Chao Li Shan-Shan Zhou Tian-Le Shi Ai-Chu Ma Cong-Wen Yu Chan Gao Guang-Lei Cao Wei Zhao Shuai Nie Jing-Fang Guo Si-Qian Jiao Xue-Chan Tian Xue-Mei Yan Yu-Tao Bao Quan-Zheng Yun Xin-Zhu Wang Ilga Porth Yousry AEl-Kassaby Xiao-Ru Wang Zhen Li Yves Van de Peer Jian-Feng Mao | 2021 | Horticulture Research2021，8，1： | 3 |
| 7 | Impact of integrated positron emission tomography and computed tomography on staging and management of gallbladder cancer and cholangiocarcinoma显示文摘 | Henrik Petrowsky Peer Wildbrett Daniela B. Husarik Thomas F. Hany Simona Tam Wolfram Jochum Pierre-Alain Clavien | 2006 | Journal of Hepatology2006，，1： | 2 |
| 8 | 香石竹镰刀菌枯萎病的生物防治显示文摘吞石竹(carnation)是世界主要切花品种之一。香石竹镰刀菌枯萎病(Fusariumoxysporum f.sp.dianthi)是生产上的重要病害。该病菌为土壤习居菌,土壤处理及化学防治效果均不理想。近年来各国试图从抗病育种和生物防治来探索防治该病的有效途径。本项研究包括:从香石竹根围分离筛选萤光假单胞细菌菌株,对筛选菌株X.13,WCS417及WCS358进行体外拮抗作用测定。 | 徐同 R.van Peer H.Rattink B.Schippers | 1989 | 科技通报1989，5，1： | 2 |
| 9 | Canonical Workflows to Make Data FAlR显示文摘The FAIR principles have been accepted globally as guidelines for improving data-driven science and data management practices,yet the incentives for researchers to change their practices are presently weak.In addition,data-driven science has been slow to embrace workflow technology despite clear evidence of recurring practices.To overcome these challenges,the Canonical Workflow Frameworks for Research(CWFR)initiative suggests a large-scale introduction of self-documenting workflow scripts to automate recurring processes or fragments thereof.This standardised approach,with FAIR Digital Objects as anchors,will be a significant milestone in the transition to FAIR data without adding additional load onto the researchers who stand to benefit most from it.This paper describes the CWFR approach and the activities of the CWFR initiative over the course of the last year or so,highlights several projects that hold promise for the CWFR approaches,including Galaxy,Jupyter Notebook,and RO Crate,and concludes with an assessment of the state of the field and the challenges ahead. | Peter Wittenburg Alex Hardisty Yann Le Franc Amirpasha Mozaffari Limor Peer Nikolay A.Skvortsov Zhiming Zhao Alessandro Spinuso | 2022 | Data Intelligence2022，4，2： | 2 |
| 10 | Overcoming multidrug resistance with nanomedicines显示文摘 | Assaf Ganoth Keren Cohen Merimi Dan Peer | 2015 | Expert Opinion on Drug Delivery2015，，2： | 2 |
| 11 | Common and epithelioid variants of hepatic angiomyolipoma exhibit clonal growth and share a distinctive immunophenotype显示文摘 | Peer Flemming Ulrich Lehmann Thomas Becker Jürgen Klempnauer Hans Kreipe | 2000 | Hepatology2000，，： | 2 |
| 12 | Acknowledgments to reviewers of World Journal of Biological Chemistry显示文摘Many reviewers have contributed their expertise and time to the peer review,a critical process to ensure the quality of World Journal of Biological Chemistry.The | Many reviewers have contributed their expertise and time to the peer review,a critical process to ensure the quality of World Journal of Biological Chemistry.The editors | 2011 | World Journal of Biological Chemistry2011，2，9： | 2 |
| 13 | Auxin transport显示文摘 | JOSHUAJ BLAKESLEE WENDY A PEER | 2005 | Current Opinion in Plant Biology2005，，8： | 1 |
| 14 | A study ofglyoxylic acid systhesis in an undividedce 11 显示文摘 | Colboume AP Peer SD | 1990 | Electrochimica Acta1990，35，3： | 1 |
| 15 | Second generation biofuels:high efficiency microalgae for biodiesel production显示文摘 | Peer M S Skye R T Evan S | 2008 | Bioenergy Research2008，1，： | 1 |
| 16 | The neglected free fat graft, its behavior and clinical use显示文摘 | Peer LA | 1956 | Am J Surg1956，92，1： | 1 |
| 17 | Identification of miR- 145 as a key regulator of the pigmentary process 显示文摘 | Dynoodt P Mestdagh P Van Peer G | 2013 | J Invest Dermatol2013，133，1： | 1 |
| 18 | PAL2NAL: Robust con version of protein sequence alignments into the corre sponding codon alignments 显示文摘 | Mikita S David T Peer B | 2006 | Nucleic Acids Res2006，34，： | 1 |
| 19 | Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo显示文摘 | Wenwen Chien Dhong Hyun Lee Yun Zheng Peer Wuensche Rosie Alvarez Ding Ling Wen Ahmed M. Aribi Su Ming Thean Ngan B. Doan Jonathan W. Said H. Phillip Koeffler | 2014 | Mol. Carcinog2014，，9： | 1 |
| 20 | The measurement of species of diversity显示文摘 | Peer R K | 1974 | Annum Review of Ecology and Systematics1974，5，： | 1 |
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