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| 1 | Tree-ring precipitation records from Baiyinaobao, Inner Mongolia since A.D. 1838显示文摘Correlation function analysis shows that total precipitation from April to early July (to July 10) in growing season limits the ring width of Picea Koraiensis significantly in Baiyinaobao, Xilinhot, Inner Mongolia. Thus a transfer function is designed to reconstruct the total precipitation from April to early July over the region for the last 160 years. The explained variance of the reconstruction is 49.3% (and 45.7% when adjusted for loss of degrees of freedom, N = 31, r = 0.702, F = 13.608, p < 0.0001). There are three relatively wet periods in the reconstruction which are: 1869—1875, 18861921 and 19431968, and four relatively dry periods: 1851—1868, 1876—1885, 1922—1943 and 1969—1999. Among them, the wet periods of 1886—1921 and 1943—1968, and the dry period of 1922—1943 appeared almost at the same time with those in Mt. Qilian region. Meanwhile, the dry period of 1922—1943 corresponds to high temperature and low rainfall during the 1920s and thereafter, and wetness of 1943—1968 corresponds very well to low temperature and more precipitation after the 1940s in Northwest, Northern China and the Changjiang River drainage basin. Calculation shows that the reconstruction series is significantly correlated with local dry-wet index (r = -0.234, p < 0.007, N = 143). Wavelet analysis indicates that there is a 22-a cycle in the precipitation of April to early July during 18381920, and an 11-a cycle during 1920—1952. No more cycles that reach 95% confidence limits are identified after 1953. The precipitation from April to early July quickly dropped into low during the 1920s. After 1950, precipitation shows a declining trend, but the reconstruction shows a tendency of increase in the late of 1990s. | LIU Yu CAI Qiufang Park Won-Kyu AN Zhisheng MA Limin | 2003 | Chinese Science Bulletin2003，48，11： | 29 |
| 2 | 主要人参皂甙的分布和比例及人参产品的质量控制显示文摘采用反相高效液相色谱法,对150多种西洋参、人参及三七的根、叶及其产品进行了分析。以8种主要的人参皂甙Rg,Re,Rf,Rb1,Rc,Rb2,Rg2和Rd作为对照品,来评价人参及其产品的质量,这8种人参皂甙的分布及其比例在对人参及其商品的定性、定量分析方面具有显著的意义。本文首次提出了单体皂甙的含量比率这一有价值的数据在人参品种及不同用药部位鉴定方面的有效性。 | Ma Yuanchun Luo Mai Lynn Malley Monique Doucet(Celex Laboratories Inc., Atholville Industrial Park, 77 Comeau St.,P. O. Box 428,Atholville,New Brunswick CANADA EOK 1A0) | 1996 | 中国药物化学杂志1996，6，1： | 12 |
| 3 | The role of hepatitis B virus X protein is related to its differential intracellular localization显示文摘长期的肝炎 B 病毒(HBV ) 感染强烈与 hepatocellular 癌被联系了。HBV 编码 oncogenic 肝炎 B 病毒 X 蛋白质(HBx ) ,它是通过和主机因素的直接、间接的相互作用调制信号 transduction,抄写,房间周期进步,蛋白质降级, apoptosis,和基因稳定性的一个多功能的管理者。HBx 的 subcellular 本地化主要是细胞质的,与在原子核的小部分。另外, HBx 表示高级导致反常 mitochondrial 分布。HBx 的动态分发能对在 HBV 生命周期的不同阶段的 HBx 的多重功能重要。这短评论作为它的细胞内部的本地化的功能给出 HBx 的微分角色的概述。 | Jingwei Ma Tucheng Sunt Sujin Park Guanxin Shen Junwei Liu | 2011 | Acta Biochimica et Biophysica Sinica2011，43，8： | 6 |
| 4 | Effect of acupuncture at Renying(ST 9) on gene expression profile of hypothalamus in spontaneously hypertensive rats显示文摘OBJECTIVE: To investigate changes in gene expression profiles in the hypothalamus related to the effects of acupuncture at the Renying(ST 9) acupoint in spontaneously hypertensive(SH) rats.METHODS: We randomly divided 18 SH rats into Renying(ST 9) group and model control group, 9 body weight-matched Wistar-Kyoto rats were used as blank controls. Acupuncture was performed manually for 20-min daily over 28 d in the Renying(ST 9) group. Rat Gene 2.0 array technology was used for the determination of gene expression profiles and the screened key genes were verified by real-time quantitative polymerase chain reaction(RT-PCR) analyses.RESULTS: The different groups exhibited differential gene expression: compared with the blank control group, 48 genes were up-regulated and 91 genes were down-regulated in the model group;compared with the model group, 79 genes were up-regulated and 80 genes were down-regulated in Renying(ST 9) group. The RT-PCR results of the key genes including Chi3 l1, Ephx2, Klk1, 5-HT1 A and Cbs were consistent with that of gene chip analysis.CONCLUTION: Acupuncture at Renying(ST 9)could significantly lower the blood pressure of SH rats and affect their hypothalamic gene expression profile. Genes associated with the contraction of vascular smooth muscle and the regulation of inflammation, neurotransmitters may be involved in acupuncture's antihypertensive mechanism. | Guo Yan Lu Juan Liang Jingrong Zhao Ruili Xu Jing Zhang Wei Park Kibeum Zhu Shipeng Chen Huan Ma Liangxiao | 2018 | Journal of Traditional Chinese Medicine2018，38，2： | 4 |
| 5 | Ipomoea batatas HKT1 transporter homolog mediates K^+ and Na^+ uptake in Saccharomyces cerevisiae显示文摘Soil salinity causes the negative effects on the growth and yield of crops. In this study,two sweet potato(Ipomoea batatas L.) cultivars,Xushu 28(X-28) and Okinawa 100(O-100),were examined under 50 and 100 mmol L^(–1) Na Cl stress. X-28 cultivar is relatively high salt tolerant than O-100 cultivar. Interestingly,real-time quantitative polymerase chain reaction(RT-q PCR) results indicated that sweet potato high-affinity K^+ transporter 1(IbHKT1) gene expression was highly induced by 50 and 100 mmol L^(–1) Na Cl stress in the stems of X-28 cultivar than in those of O-100 cultivar,but only slightly induced by these stresses in the leaves and fibrous roots in both cultivars. To characterize the function of IbHKT1 transporter,we performed ion-flux analysis in tobacco transient system and yeast complementation. Tobacco transient assay showed that IbHKT1 could uptake sodium(Na^+). Yeast complementation assay showed that IbHKT1 could take up K^+ in 50 mmol L^(–1) K^+ medium without the presence of Na Cl. Moreover,Na^+ uptake significantly increased in yeast overexpressing IbHKT1. These results showed that IbHKT1 transporter could have K^+-Na^+ symport function in yeast. Therefore,the modes of action of IbHKT1 in transgenic yeast could differ from the mode of action of the other HKT1 transporters in class I. Potentially,IbHKT1 could be used to improve the salt tolerance nature in sweet potato. | PARK Sung-chul YU Yi-cheng KOU Meng YAN Hui TANG Wei WANG Xin LIU Ya-ju ZHANG Yun-gang KWAK Sang-soo MA Dai-fu SUN Jian LI Qiang | 2017 | Journal of Integrative Agriculture2017，16，10： | 3 |
| 6 | Risk factors of electrocoagulation syndrome after esophageal endoscopic submucosal dissection显示文摘AIM To investigate post endoscopic submucosal dissection electrocoagulation syndrome(PEECS) of the esophagus.METHODS We analyzed 55 consecutive cases with esophageal endoscopic submucosal dissection for superficial esophageal squamous neoplasms at a tertiary referral hospital in South Korea. Esophageal PEECS was defined as 'mild' meeting one of the following criteria without any obvious perforation: fever(≥ 37.8 ℃), leukocytosis(> 10800 cells/μl), or regional chest pain more than 5/10 points as rated on a numeric pain intensity scale. The grade of PEECS was determined as 'severe' when meet two or more of above criteria.RESULTS We included 51 cases without obvious complications in the analysis. The incidence of mild and severe esophageal PEECS was 47.1% and 17.6%, respectively. Risk factor analysis revealed that resected area, procedure time, and muscle layer exposure were significantly associated with PEECS. In multivariate analysis, a resected area larger than 6.0 cm^2(OR = 4.995, 95%CI: 1.110-22.489, P = 0.036) and muscle layer exposure(OR = 5.661, 95%CI: 1.422-22.534, P = 0.014) were independent predictors of esophageal PEECS. All patients with PEECS had favorable outcomes with conservative management approaches, such as intravenous hydration or antibiotics.CONCLUSION Clinicians should consider the possibility of esophageal PEECS when the resected area exceeds 6.0 cm^2 or when the muscle layer exposure is noted. | Dae Won Ma Young Hoon Youn Da Hyun Jung Jae Jun Park Jie-Hyun Kim Hyojin Park | 2018 | World Journal of Gastroenterology2018，24，10： | 3 |
| 7 | The mitochondrial genome encodes abundant small noncoding RNAs显示文摘识别的小 noncoding RNA 都被原子染色体远因此编码。这里,我们主要报导鼠科、人的 mitochondrial 染色体编码几千小 noncoding RNA,它是源于 mitochondrial 基因(主人基因) 的感觉抄本,并且我们称为这些小 RNA mitochondrial 编码染色体的小 RNA (mitosRNAs ) 。影响的 DICER inactivation,但是完全没废除 mitosRNA 生产。MitosRNAs 看起来是当前未辩别出的 mitochondrial ribonucleases 的产品。提高的表示在 vitro 他们的主人基因铺平的 mitosRNAs 的 Overexpression,和 dysregulated mitosRNA 表示通常在 vivo 与异常 mitochondrial 基因表示被联系。我们的数据证明除了 37 已知的 mitochondrial 基因,哺乳动物的 mitochondrial 染色体也编码丰富的 mitosRNAs,它可以在房间在 mitochondrial 基因表示的控制起一个重要规章的作用。 | Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W Hennig Huili Zheng Yung-Ming Lin2 Loredana Moro Jer-Tsong Hsieh wei Yant | 2013 | Cell Research2013，23，6： | 3 |
| 8 | Dietary energy sources and levels shift the multi-kingdom microbiota and functions in the rumen of lactating dairy cows显示文摘Background: Dietary energy source and level in lactation diets can profoundly affect milk yield and composition.Such dietary effects on lactation performance are underpinned by alteration of the rumen microbiota, of which bacteria, archaea, fungi, and protozoa may vary differently. However, few studies have examined all the four groups of rumen microbes. This study investigated the effect of both the level and source of dietary energy on rumen bacteria, archaea, fungi, and protozoa in the rumen of lactating dairy cows. A 2 × 2 factorial design resulted in four dietary treatments: low and high dietary energy levels(LE: 1.52–1.53;and HE: 1.71–1.72 Mcal/kg dry matter) and two dietary energy sources(GC: finely ground corn;and SFC: steam-flaked corn). We used a replicated 4 × 4 Latin square design using eight primiparous Chinese Holstein cows with each period lasting for 21 d. The rumen microbiota was analyzed using metataxonomics based on kingdom-specific phylogenetic markers [16 S r RNA gene for bacteria and archaea, 18 S r RNA gene for protozoa, and internally transcribed spacer 1(ITS1) for fungi] followed with subsequent functional prediction using PICRUSt2.Results: The GC resulted in a higher prokaryotic(bacterial and archaeal) species richness and Faith's phylogenetic diversity than SFC. For the eukaryotic(fungi and protozoa) microbiota, the LE diets led to significantly higher values of the above measurements than the HE diets. Among the major classified taxa, 23 genera across all the kingdoms differed in relative abundance between the two dietary energy levels, while only six genera(none being protozoal)were differentially abundant between the two energy sources. Based on prokaryotic amplicon sequence variants(ASVs) from all the samples, overall functional profiles predicted using PICRUSt2 differed significantly between LE and HE but not between the two energy sources. Fish Taco analysis identified Ruminococcus and Coprococcus as the taxa potentially contributing to the enriched KEGG pathways for biosynthesis of amino acids and to the metabolisms of pyruvate, glycerophospholipid, and nicotinate and nicotinamide in the rumen of HE-fed cows. The co-occurrence networks were also affected by the dietary treatments, especially the LE and GC diets, resulting in distinct co-occurrence networks. Several microbial genera appeared to be strongly correlated with one or more lactation traits.Conclusions: Dietary energy level affected the overall rumen multi-kingdom microbiota while little difference was noted between ground corn and steam-flaked corn. Some genera were also affected differently by the four dietary treatments, including genera that had been shown to be correlated with lactation performance or feed efficiency.The co-occurrence patterns among the genera exclusively found for each dietary treatment may suggest possible metabolic interactions specifically affected by the dietary treatment. Some of the major taxa were positively correlated to milk properties and may potentially serve as biomarkers of one or more lactation traits. | Tansol Park Lu Ma Ying Ma Xiaoqiao Zhou Dengpan Bu Zhongtang Yu | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 3 |
| 9 | New synthesis of amphiphilic copolymers PE-g-PEO via esterfication显示文摘A new series of high molecular weight amphi-philic graft copolymers PE-g-PEO has been prepared. The esterifications between PE-p-MS-g-MA and PEO with OH group at the chain end are carried out under different condi-tions. The compositions of these graft copolymers are studied by NMR and FTIR. It is found to be a convenient and effi-cient way to prepare high molecular weight PE-g-PEO graft copolymers. | L?Yingying1, MA Zhi1,2, HU Youliang1, XU G. X.3 & CHUNG T. C.3 1. State Key Laboratory of Engineering Plastics, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Bei-jing Beijing Lab of Catalysis, Key Lab of Catalysis of China Na-tional Petroleum Corporation, Beijing 100080, China 2. Graduate School of Chinese Academy of Sciences, Beijing 100039, China 3. Department of Material Science and Engineering, Pennsylvania State University, University Park, PA 16802, USA | 2003 | Chinese Science Bulletin2003，48，6： | 2 |
| 10 | 18 F-fluorodeoxyglucose positron emission tomography–computed tomography for the evaluation of bone metastasis in patients with gastric cancer显示文摘 | Dae Won Ma Jie-Hyun Kim Tae Joo Jeon Yong Chan Lee Mijin Yun Young Hoon Youn Hyojin Park Sang In Lee | 2013 | Digestive and Liver Disease2013，，： | 2 |
| 11 | Structural,Electrical and Optical PropoSes of Aluminum Doped Zinc Oxide Films Prepared by Radio Frequency Magnetron Sputtering显示文摘 | Park K C Ma D Y | 1997 | Appl Phys1997，81，12： | 1 |
| 12 | Sorafenib ac- tivates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells显示文摘 | Park MA Reinehr R Haussinger D | 2010 | Mol Cancer Ther2010，9，8： | 1 |
| 13 | The physical prop- erties of Al-doped zinc oxide films prepared by RF magnetron sputtering 显示文摘 | Park K C Ma D Y Kim K H | 1997 | Thin Solid Films1997，305，12： | 1 |
| 14 | Growth suppression of hmnan leukemic cells in vitro by ascorbic cacid显示文摘 | Park CH Amare M Savin MA | 1980 | Cancer Res1980，40，： | 1 |
| 15 | Protection of nigral neurons by GDNF-engineered marrow cell transplantation 显示文摘 | PARK KW EGLITIS MA MOURADIAN MM | 2000 | Neurosci Res2000，40，4： | 1 |
| 16 | Primary (AL) hepatic amyloidosis:clinical features and natural history in 98 patients显示文摘 | Park MA Mueller PS Kyle RA | 2003 | Medicine2003，82，5： | 1 |
| 17 | Hepatocyte transplantation: clinical and experimental application显示文摘 | Ohashi K Park F Kay MA | 2001 | J Mol Meal2001，79，11： | 1 |
| 18 | Human mannose-binding lectin and L-ficolin function as specific pattern recognition proteins in the lectin activation pathway of com- plement显示文摘 | Ma YG Cho MY Zhao M Park JW Matsushita M Fujita T | 2004 | J Biol Chem2004，279，25： | 1 |
| 19 | Molecular genetiC diversity and population structure in Lycium accessions using SSR markers显示文摘 | Zhao W G Chung J W Cho Y I Rha W H Lee G A Ma K H Han S H Bang K H Park C B Kim S M Park Y J | 2010 | C R Bioi2010，333，： | 1 |
| 20 | A modified damage model for advanced high strength steel sheets显示文摘 | Chung K Ma N Park T | 2011 | Inter J Plasticity2011，27，10： | 1 |
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