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| 1 | Anti-diabetic activity of quercetin extracted from Phyllanthus emblica L.fruit: In silico and in vivo approaches显示文摘In this study, molecular interactions of the ligands, quercetin, gallic acid, and metformin with various diabetes mellitus-related protein targets, such as glycogen phosphorylase and peroxisome proliferatoractivated receptor gamma, were assessed. It was revealed that quercetin possesses good binding affinity to both targets. Quercetin is a major constituent of methanolic extracts of Phyllanthus emblica fruit. The antihyperglycemic effect of quercetin in streptozotocin(STZ)-induced diabetic rats was examined. The isolated quercetin administered at a dose of 75 mg/kg body weight produced a maximum decrease of14.78% in blood glucose levels in the diabetic rats after 7 days of treatment. Furthermore, quercetin doses of 50 and 75 mg/kg were shown to significantly improve the profiles of triglycerides, high-density lipoprotein, very-low-density lipoprotein, low-density lipoprotein, and total cholesterol at the end of the study in STZ-induced diabetic rats. The administration of quercetin(25, 50, and 75 mg/kg body weight)daily for 28 days in STZ-induced diabetic rats resulted in a significant decrease in blood glucose and urine sugar levels, with a considerable rise in plasma insulin and hemoglobin levels. Therefore, quercetin is a potential drug with antidiabetic and antihyperglycemic action mediated by changes in the levels of glucose, cholesterol, and triglycerides as indicated by in silico and in vivo studies. | Prabhu Srinivasan S.Vijayakumar Swaminathan Kothandaraman Manogar Palani | 2018 | Journal of Pharmaceutical Analysis2018，8，2： | 18 |
| 2 | Experimental and CFD Heat Transfer Studies of Al2O3-Water Nanofluid in a Coiled Agitated Vessel Equipped with Propeller显示文摘这份报纸与推进器煽动者在一个卷的鼓动的容器论述 Al2O3 水 nanofluid 的热转移特征。试验性的学习用 Al2O3 水 nanofluids 的 0.10% , 0.20% 和 0.30% 体积集中被进行。结果用 nanofluids 显示出对流的热转移的可观的改进。以雷纳兹数字, Prandtl 数字,粘性比率和体积集中为 Nusselt 数字开发的实验关联与在内的试验性的数据适合 ?? 憈? | Thangavelu Perarasu Mahizhnan Arivazhagan Palani Sivashanmugam | 2013 | Chinese Journal of Chemical Engineering2013，21，11： | 7 |
| 3 | Anti-chikungunya activity of luteolin and apigenin rich fraction from Cynodon dactylon显示文摘Objective:To obtain Iuteolin and apigenin rich fraction from the ethanolic extract of Cynodon dactylon(L.)(C.dactylon) Pers and evaluate the fraction's cytotoxicity and anti-Chikungunya potential using Vero cells.Methods:The ethanolic extract of C.dactylon was subjected to silica gel column chromatography to obtain anti-chikungunya virus(CHIKV) fraction.Reverse phase-HPLC and GC-MS studies were carried out to identily the major phytochemicals in the fraction using phylochemical standards.Cytotoxicity and the potential of the fraction against CHIKV were evaluated in vitro using Vero cells.Reduction in viral replication was assessed by reverse transcriptase-polymerase chain reaction(RT-PCR) after treating the viral infected Vero cells with the fraction.Results:Reverse Phase-HPLC and GC-MS studies confirmed the presence of flavonoids,luteolin and apigenin as major phytochemicals in the anti-CHIKV ethanolic fraction of C.dactylon- The fraction was found to exhibit potent viral inhibitory activity(about 98%) at the concentration of 50 μg/mL as observed by reduction in cytopathic effect,and the cytotoxic concentration of the fraction was found to be 250 μg/mL.RT-PCR analyses indicated that the reduction in viral mRNA synthesis in fraction treated infected cells was much higher than the viral infected control cells.Conclusions:Luteolin and apigenin rich ethanolic fraction from C.dactylon can be utilized as a potential therapeutic agent against CHIKV infection as the fraction does not show cytotoxicity while inhibiting the virus. | Krishnan Saravana Murali Srinivasan Sivasubramanian Savariar Vincent Shanmugaraj Bala Murugan Bupesh Giridaran Sundaram Dinesh Palani Gunasekaran Kaveri Krishnasamy Ramalingam Sathishkumar | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，5： | 5 |
| 4 | 原始的摔跤运动显示文摘Kushti摔跤是一种古老的摔跤运动,有3000年的历史,起源于印度,之后传播到伊朗和中东。如今在印度的一些小地方仍在进行这种摔跤运动,但主要还是在印度西部的戈尔哈布尔市,这里聚集了该项目最优秀的学校、运动员和教练。此组照片是第八届国际新闻摄影比赛(华赛)体育类新闻组照优秀奖获奖作品。 | Palani Mohan | 2012 | 南风窗2012，，8： | 2 |
| 5 | Confinement Effect of Glass Fabrics Bonded with Cementitious and Organic Binders显示文摘 | Smitha Gopinath Nagesh R. Iyer Ravindra Gettu G.S. Palani A. Ramachandra Murthy | 2011 | Procedia Engineering2011，，： | 2 |
| 6 | Cavernous hemangioma arising from the gastro-splenic ligament: A case report显示文摘We present a rare case of a 45-year-old woman who presented with epigastric pain associated with early satiety and weight loss. Imaging revealed a large intraabdominal mass in the epigastrium. Despite intensive investigations, including ultrasound scanning, computed tomography, upper gastrointestinal endoscopy, and percutaneous biopsy, a diagnosis could not be obtained. A histological diagnosis of cavernous hemangioma arising from the gastro-splenic ligament was confirmed after laparoscopic excision and histological examination of the intra-abdominal epigastric mass. | Kin-Fah Chin Ghaith Khair Palani Sathish Babu David Russell Morgan | 2009 | World Journal of Gastroenterology2009，15，30： | 2 |
| 7 | Total parenteral nutrition during acute pancreatitis: Clinical experience with 156 Patients显示文摘 | Arnold P. Robin M.D. Rebecca Campbell R.D. Colathur K. Palani M.D. Katherine Liu M.D. Philip E. Donahue M.D. Lloyd M. Nyhus M.D | 1990 | World Journal of Surgery1990，，5： | 2 |
| 8 | Effect of process parameters on springback behaviour during air bending of electrogalvanised steel sheet显示文摘This work aims to study the springback behaviour of electrogalvanised (EG) steel sheets during the air bending process.Experiments have been conducted to analyse the influence of various parameters such as coating thickness,orientation of the sheet,punch radius,die radius,die opening,punch velocity,and punch travel on springback behaviour.It is established that the springback increases with increasing coating thickness,punch radius,punch travel,die radius,die opening,and punch velocity.The 90° orientation exhibits higher springback than 0° orientation. | Durairaj VASUDEVAN Rajumani SRINIVASAN Palani PADMANABHAN | 2011 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2011，12，3： | 2 |
| 9 | Total parental nutrition during acute pancreatitis:clinical experience with 156 patients显示文摘 | Robin AP Campbell R Palani CK | 1990 | World J Surg1990，14，4： | 1 |
| 10 | Copper-cata-lyzed decarboxylative three-component reactions for the synthesis of imidazo[1,2-α]pyridines显示文摘 | PALANI T PARK K KUMAR M R | | 0，，26： | 1 |
| 11 | One-pot synthesis of ordered and stable cubic mesoporous silica SBA-1 functionalized with amino functional groups显示文摘 | KAO H M LIAO C H PALANI A | 2008 | Microporous Mesoporous Mater2008，113，13： | 1 |
| 12 | Total parenteral nutrition during acute pancreatitis: clinical experience with 156 patients显示文摘 | Robin AP Campbell R Palani CK | 1990 | World J Surg1990，14，： | 1 |
| 13 | Microcellular polymeric materials from microemulsions:control of microstmcture and morphology显示文摘 | Palani Raj W R Sasthav M Cheung H M | 1993 | J Appl Polym Sci1993，47，3： | 1 |
| 14 | Sol-gel preparation and characterization of alkaline earth metal doped nano TiO2 : Efficient photocatalytic degradation of 4-chlorophenol 显示文摘 | Venkat N Palani M Murug V | 2007 | Mole Cata A : Chem2007，273，1： | 1 |
| 15 | Development of mathematical models for prediction of weld bead geometry in cladding by flux cored arc welding显示文摘 | Palani P K Murugan N | 2006 | International Journal of Advanced Manufactur- ing Technology2006，30，78： | 1 |
| 16 | Microcellular polymeric materials from microemulsions:Control of microstructure and morphology显示文摘 | Palani Raj W R Sasthav M Michael Cheng H | 1993 | Journal of Applied Polymer Science1993，47，3： | 1 |
| 17 | 显示文摘 | Palani R W R Sasthav M Cheung H M | 1995 | Polymer1995，13，： | 1 |
| 18 | Safety of regadenoson as a pharmacologic stress agent for myocardial perfusion imaging in chronic kidney disease patients not on hemodialysis显示文摘 | Palani G Husain Z Salinas RC | 2011 | J Nucl Cardiol2011，18，4： | 1 |
| 19 | Selection of parameters of pulsed current gas metal arc welding显示文摘 | Palani P K Murugan N | 2006 | Journal of Materials Processing Technology2006，172，2： | 1 |
| 20 | Optimization of weld bead geometry for stainless steel claddings deposited by FCAW 显示文摘 | PALANI P K MURUGAN N | 2007 | Journal of Materials Processing Technology2007，190，： | 1 |
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