|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Laser ablation for small hepatocellular carcinoma: State of the art and future perspectives显示文摘During the last two decades, various local thermal ablative techniques for the treatment of unresectable hepatocellular carcinoma(HCC) have been developed. According to internationally endorsed guidelines, percutaneous thermal ablation is the mainstay of treatment in patients with small HCC who are not candidates for surgical resection or transplantation. Laser ablation(LA) represents one of currently available loco-ablative techniques. In this article, the general principles, technique, image guidance, and patient selection are reported. Primary effectiveness, long-term outcome, and complications are also discussed. A review of published data suggests that LA is equivalent to the more popular and widespread radiofrequency ablation in both local tumor control and long-term outcome in the percutaneous treatment of early HCC. In addition, the LA technique using multiple thin laser fibres allows improved ablative effectiveness in HCCs greater than 3 cm. Reference centres should be equipped with all the available techniques so as to be able to use the best and the most suitable procedure for each type of lesion for each patient. | Giovan Giuseppe Di Costanzo Giampiero Francica Claudio Maurizio Pacella | 2014 | World Journal of Hepatology2014，6，10： | 14 |
| 2 | An eighteen-month follow-up study on the effects of Intravitreal Dexamethasone Implant in diabetic macular edema refractory to anti-VEGF therapy显示文摘AIM: To evaluate the long-term efficacy and safety of dexamethasone implants in subjects affected by diabetic macular edema(DME) resistant to anti-vascular endothelial growth factor(VEGF) therapy.METHODS: Thirty-two DME patients were enrolled.A700 microgram slow release Intravitreal Dexamethasone Implant(Ozurdex~) was placed in the vitreous cavity.All patients were followed for 18 mo.Best-corrected visual acuity(BCVA) measured with Early Treatment Diabetic Retinopathy Study(ETDRS) and central macular thickness(CMT) exams were carried out at baseline(T0)and after 1(T1),3(T3),4(T4),6(T6),9(T9),12(T12),15(T15),and 18mo(T18) post injection. RESULTS: Repeated measures ANOVA showed an effect of treatment on ETDRS(P<0.0001).Post hoc analyses revealed that ETDRS values were significantly increased at T1,T3,T4,T9,and T15(P <0.001) as compared to baseline value(T0).At T6,T12,and T18,ETDRS values were still statistically higher than baseline(P<0.001 vs T0).However,at these time points,we observed a trend to return to baseline conditions.ANOVA also showed an effect of treatment(P <0.0001).CMT decreased significantly at T1,T3,T4,T9,and T15(P<0.001).At T6(P<0.01),T12 and T18(P<0.001) CMT was also significantly lower than T0 although a trend to return to the baseline conditions was also observed.CONCLUSION: Our findings demonstrate that Intravitreal Dexamethasone Implant is a good option to improveBCVA and CMT in DME patients resistant to anti-VEGF therapy.Our data also show that the use of drugs administered directly into the vitreous allows achieving appropriate and long-lasting concentration at the site of disease without systemic side effects. | Fernanda Pacella Maria Rosaria Romano Paolo Turchetti Giovanna Tarquini Anna Carnovale Antonella Mollicone Alessandra Mastromatteo Elena Pacella | 2016 | International Journal of Ophthalmology(English edition)2016，9，10： | 5 |
| 3 | Percutaneous ultrasounal guided ethanol injection: a new treatment of toxic autonomously functioning thyroid nodules显示文摘 | Papini E Panumzi C Pacella C M | 1993 | J Clin Endocrinol Metab1993，76，2： | 2 |
| 4 | Papillary carcinoma insmall hypoechoic thyroid nodules:predictive value of echo colorDoppler evaluative显示文摘 | Pacella CM Guglielmi R Fabbrini R | 1998 | Exp Clin Cancer Res1998，17，2： | 1 |
| 5 | Percutaneous Laser Ablation in the Treatment of Hepatocellular Carcinoma with Small Tumors: Analysis of Factors Affecting the Achievement of Tumor Necrosis显示文摘 | Claudio Maurizio Pacella Giancarlo Bizzarri Giampiero Francica Antonio Bianchini Stefano De Nuntis Sara Pacella Anna Crescenzi Silvia Taccogna Giuseppe Forlini Zaccaria Rossi John Osborn Roberto Stasi | 2005 | Journal of Vascular and Interventional Radiology2005，，11： | 1 |
| 6 | Thyroid tissue: US-guided percutaneous laser thermal ablation显示文摘 | Pacella CM Bizzarri Spiezia S et ol | 2004 | Radiology2004，232，1： | 1 |
| 7 | Hepatocelluar carcinoma:long term result of combined treatment with laser thermal ablation and transcatheter arterial chemoembolization显示文摘 | PACELLA C M BIZZARRI G CECCONI P | 2001 | Radiology2001，219，3： | 1 |
| 8 | Clinicalreview: Nonsurgical, image-guided, minimally invasivetherapy for thyroid nodules显示文摘 | GHARIB H HEGED?S L PACELLA C M | 2013 | J Clin Endocrinol Metab2013，98，10： | 1 |
| 9 | Thyroid tissue:US-guided percutaneous laser thermal ablation显示文摘 | PACELLA C M BIZZARRI G SPIEZIA S | 2004 | Radiology2004，232，1： | 1 |
| 10 | 查看详情显示文摘 | Drew K Renfrew P. D Craven T. W Butterfoss G.L. Chou F.C. Lyskov S. Bullock B.N. Watkins A. Labonte J.W. Pacella M. Kilambi K.P. Leaver-Fay A. Kuhlman B. Gray J.J. Bradley P. Kirshenbaum K. Arora P.S. Das R. Bonneau R | | 0，，7： | 1 |
| 11 | Women with reduced ovarian reserve or advanced maternal age have an altered follicular environment 显示文摘 | Pacella L Zander-Fox DL Armstrong DT | 2012 | Fertil Steril2012，98，： | 1 |
| 12 | Eyelid reconstruc- tion 显示文摘 | Alghoul M Pacella SJ McClellan WT | 2013 | Plast Reconstruct Surgery2013，132，2： | 1 |
| 13 | Endometriosis of the abdominal wall显示文摘 | Rulli F Pacella A | 1998 | Acta Biomedica de L'' Ateneo Parmense1998，69，56： | 1 |
| 14 | Primary malignant melanoma of the bladder显示文摘 | Pacella M Gallo F Gastaldi C | | 0，，05： | 1 |
| 15 | Thyroid tissue:US-guided percutaneous laser thermal ablation显示文摘 | Pacella CM Bizzarri G Spiezia S | | 0，，01： | 1 |
| 16 | Laser thermal ablation in the treatment of small hepatocellular carcinoma:results in 74 patients显示文摘 | Pacella CM Bizzarri G Magnolfi F | 2001 | Radiology2001，221，3： | 1 |
| 17 | On the Use of Principal Component Analysis to Identify Systematic Pat terns in Roundness Profiles显示文摘 | Colosimo B M Pacella M | 2007 | Quality and Relia- bility Engineering International2007，23，6： | 1 |
| 18 | Object-oriented modeling and simulation of flexible manufacturing system: a rule-based procedure显示文摘 | ANGLANIA GRIECO A PACELLA M | 2002 | Simulation Modeling Practice and Theory2002，10，3： | 1 |
| 19 | Object-oriented modeling and simulation of flexible manufacturing sys- tems: a rule-based procedure显示文摘 | Anglani A Grieco A Pacella M | 2002 | Simulation Modelling Practice and Theory2002，10，2： | 1 |
| 20 | Treatment of Microvascular Micro-embolization Using Microbubbles and Long-Tone-Burst Ultra- sound: An inVivo, Study 显示文摘 | Pacella JJ Brands J Schnatz FG | 2015 | Ultrasound in Medicine & Biology2015，4，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员