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2028篇 您的检索式:作者名="PACE"
    题名 作者 年代 出处 被引量
1Chemical Composition and Nutritive Value of Ramie Plant [Boehmeria nivea (L.) Gaud] and Its By-Products from the Textile Industry as Feed for Ruminants显示文摘G. Conto F. Carfi V. Pace 2011Journal of Agricultural Science and Technology(A)2011,1,5:18
2全面评估乳腺癌筛查的利与弊并指导乳腺癌的筛查显示文摘摘译:在美国乳腺癌是女性第二大恶性肿瘤的死亡病因,乳腺钼靶摄片可以降低乳腺癌的病死率,但同时可造成过度诊断等伤害。作者检索1960年1月1日—2014年1月19日关于乳腺钼靶摄片利与弊的相关研究论文,结果发现乳腺钼靶摄片筛查乳腺癌可使乳腺癌总体病死率下降19%,罗勇 Pace L E Keating N L 2014临床误诊误治2014,27,5:15
3Current concepts and future strategies in the antimicrobial therapy of emerging Gram-positive spontaneous bacterial peritonitis显示文摘Spontaneous bacterial peritonitis(SBP) is the most common infection in end-stage liver disease patients.SBP is defined as an ascitic fluid infection with a polymorphonuclear leucocyte count ≥ 250/mm^3 without an evident intra-abdominal surgically treatable source.Several mechanisms contribute to SBP occurrence,including translocation of gut bacteria and their products,reduced intestinal motility provoking bacterial overgrowth,alteration of the gut's barrier function and local immune responses.Historically,Gram-negative enteric bacteria have been the main causative agents of SBP,thereby guiding the empirical therapeutic choice.However,over the last decade,a worryingly increasing prevalence of Gram-positive and multi-drug resistant(MDR) SBP has been seen.Recently,the microbiological spectrum of SBP seems to have changed in Europe due to a high prevalence of Gram-positive bacteria(48%-62%).The overall proportion of MDR bacteria is up to 22%-73% of cases.Consequently,empirical therapy based on thirdgeneration cephalosporins or amoxicillin/clavulanic acid,can no longer be considered the standard of care,as these drugs are associated with poor outcomes.Theaim of this review is to describe,with an epidemiological focus,the evidence behind this rise in Gram-positive and MDR SBP from 2000 to present,and illustrate potential targeted therapeutic strategies.An appropriate treatment protocol should include daptomycin plus ceftaroline and meropenem,with prompt stepdown to a narrower spectrum when cultures and sensitivity data are available in order to reduce both cost and potential antibiotic resistance development.Marco Fiore Alberto Enrico Maraolo Ivan Gentile Guglielmo Borgia Sebastiano Leone Pasquale Sansone Maria Beatrice Passavanti Caterina Aurilio Maria Caterina Pace 2017World Journal of Hepatology2017,9,30:13
4Gastroesophageal reflux: the features in elderlypatients显示文摘AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesophageaI refluxsymptoms, and the results were compared with112 symptomatic younger patients.RESULTS The results of 24-h pH-monitoringand endoscopy showed that the elderly patientshad pathological reflux and reflux esophagitismore frequently than the younger patients.P6rcentage time with pH< 4 in elderly patientswith reflux esophagitis was 32.5% in 24 hours,as compared with 12.9% in the younger patientswith reflux esophagitis (P < 0 .05 ). The elderlypatients with reflux esophagitis have longerP6riOds of acid reflux in both upright and Supinepositions than the younger patients. Endoscopyshowed that 20 .8% of elderIy patients had grade Ⅲ / Ⅳ esophagitis, whereas only 3.4% ofyounger patients had grade Ⅲ/ Ⅳ esophagitis(P < 0.002 ). Percentages of grades Ⅰ /Ⅱesophagitis in the two groups were 12.5% and26. 5%, respectiveIy (P< 0. 002 ).CONCLUSION Elderly patients, as comparedwith younger patients, have more severegastroesophageal reflux and esophageal lesions.The incompetence of lower esophageal sphincter and the presence of hiataI hernia may beimportant factors leading to the difference in incidence and severity of reflux esophagitisbetween elderly and younger patients.Huang X Zhu HM Deng CZ Porro GB Sangaletti O Pace F 1999World Journal of Gastroenterology1999,5,5:12
5Nosocomial spontaneous bacterial peritonitis antibiotic treatment in the era of multi-drug resistance pathogens: A systematic review显示文摘AIM To systematically review literature upon aetiology of nosocomial spontaneous bacterial peritonitis(N-SBP) given the rising importance of multidrug-resistant(MDR) bacteria.METHODS A literature search was performed on MEDLINE and Google Scholar databases from 2000 to 15 th of November 2016, using the following search strategy: 'spontaneous' AND 'peritonitis'.RESULTS The initial search through electronic databases retrieved 2556 records. After removing duplicates, 1958 records remained. One thousand seven hundred and thirty-five of them were excluded on the basis of the screening of titles and abstract, and the ensuing number of remaining articles was 223. Of these records, after careful evaluation, only 9 were included in the qualitative analysis. The overall proportion of MDR bacteria turned out to be from 22% to 73% of cases across the studies.CONCLUSION N-SBP is caused, in a remarkable proportion, by MDR pathogens. This should prompt a careful re-assessment of guidelines addressing the treatment of this clinical entity.Marco Fiore Alberto Enrico Maraolo Ivan Gentile Guglielmo Borgia Sebastiano Leone Pasquale Sansone Maria Beatrice Passavanti Caterina Aurilio Maria Caterina Pace 2017World Journal of Gastroenterology2017,23,25:9
6Outcome of nonerosive gastro-esophageal reflux disease patients with pathological acid exposure显示文摘AIM: To assess the management and outcome of nonerosive gastro-esophageal reflux disease (NERD) patients who were identified retrospectively, after a 5-year follow-up.METHODS: We included patients with gastro-esophageal reflux disease (GERD) symptoms who had a negative endoscopy result and pathological 24-h esophageal pH-monitoring while off therapy. We interviewed them after an average period of 5 years (range 3.5-7 years) by means of a structured questionnaire to assess presence of GERD symptoms, related therapy, updated en-doscopic data and other features. We assessed predictors of esophagitis development by means of univariate and multivariate statistical analysis.RESULTS: 260 patients (137 women) were included. Predominant GERD symptoms were heartburn andregurgitation in 103/260 (40%). 70% received a maintenance treatment, which was proton pump inhibitor (PPI) in 55% of cases. An average number of 1.5 symptomatic relapses per patient/year of follow-up were observed. A progression to erosive gastro-esophageal reflux disease (ERD) was found in 58/193 (30.0%) of patients undergoing repeat endoscopy; 72% of these were Los Angeles grade A-B. CONCLUSION: This study shows that progression to ERD occurs in about 5% of NERD cases per year, despite therapy. Only two factors consistently and independently influence progression: smoking and absence of PPI therapy.Fabio Pace Stefano Pallotta Gianpiero Manes Annalisa de Leone Patrizia Zentilin Luigi Russo Vincenzo Savarino Matteo Neri Enzo Grossi Rosario Cuomo 2009World Journal of Gastroenterology2009,15,45:8
7Developing More Effective Enhanced Biochar Fertilisers for Improvement of Pepper Yield and Quality显示文摘Utilization of biochar at high application rates can increase soil C and crop yields, decrease greenhouse gas emissions and reduce nutrient run-off from soils. However, the high application rate of 10 t ha-1may not return a profit to the farmer due to the high cost of biochar. In this study biochar was modified through pre-treating the biomass and post-treating with phosphoric acid, minerals and different chemical fertilisers to study the effects of two new enhanced biochar fertilisers on the yield and quality of green pepper in a field experiment with 5 fertilisation treatments and 3 replications. The two new biochar fertilisers significantly(P < 0.05) increased the yield of green pepper(11.33–11.47 t ha-1), compared with the conventional chemical fertiliser(9.72 t ha-1). The biochar fertiliser treatments improved the vitamin C content of green pepper from 236.99 to 278.28 mg kg-1, and also significantly(P < 0.05) reduced the nitrate content from 132.32 to 101.92 mg kg-1, compared with chemical fertiliser. This study indicated that, compared to the use of conventional chemical fertiliser, all of the biochar fertiliser treatments could significantly improve the yield and quality of green pepper.YAO Chunxue Stephen JOSEPH LI Lianqing PAN Genxing Yun LIN Paul MUNROE Ben PACE Sarasadat TAHERYMOOSAVI Lukas VAN ZWIETEN Torsten THOMAS Shaun NIELSEN Jun YE Scott DONNE 2015Pedosphere2015,25,5:8
8Microbiota-gut-brain axis and its affect inflammatory bowel disease:Pathophysiological concepts and insights for clinicians显示文摘Despite the bi-directional interaction between gut microbiota and the brain not being fully understood,there is increasing evidence arising from animal and human studies that show how this intricate relationship may facilitate inflammatory bowel disease(IBD)pathogenesis,with consequent important implications on the possibility to improve the clinical outcomes of the diseases themselves,by acting on the different components of this system,mainly by modifying the microbiota.With the emergence of precision medicine,strategies in which patients with IBD might be categorized other than for standard gut symptom complexes could offer the opportunity to tailor therapies to individual patients.The aim of this narrative review is to elaborate on the concept of the gutbrain-microbiota axis and its clinical significance regarding IBD on the basis of recent scientific literature,and finally to focus on pharmacological therapies that could allow us to favorably modify the function of this complex system.Emanuele Sinagra Erika Utzeri Gaetano Cristian Morreale Carlo Fabbri Fabio Pace Andrea Anderloni 2020World Journal of Clinical Cases2020,8,6:7
9高比转速轴流泵正交优化设计研究显示文摘为了研究叶轮与导叶匹配对高比转速轴流泵水力性能的影响,以一台比转速为1 500 r/min的轴流泵为研究对象,选取了叶轮与导叶的7个几何参数进行正交试验优化设计。为拓宽其高效运行范围,本次优化以三个工况点(0. 8Qd、1. 0Qd、1. 2Qd)的加权平均效率为优化目标,采用L_(18)(3~7)正交表设计了18组方案。在ANSYS CFX 14. 5中采用SST k-ω湍流模型对各方案进行定常计算。通过极差分析得到了各参数对目标影响的主次顺序并获得了最优参数组合。结果表明:优化后轴流泵加权平均效率提高了4. 68%,大流量下效率提高十分明显,而设计扬程基本不变;叶轮与导叶的动静匹配对轴流泵水力性能有重要影响。袁建平 范猛 Giovanni Pace 陆荣 李彦军 付燕霞 2018振动与冲击2018,37,22:6
10Gastroesophageal reflux and Helicobacter pylori:a review显示文摘INTRODUCTION Since the observation by Labenz et al thateradication of Helicobacter pylori(Hp)infectionmay be followed by development of refluxesophagitis in a relevant proportion of duodenalulcer patients previously not affected bygastroesophageal reflux disease(GERD),agrowing attention has been given to theF Pace G Bianchi Porro 2000World Journal of Gastroenterology2000,6,3:6
11Gastroesophageal reflux disease management according to contemporary international guidelines:A translational study显示文摘AIM:To test the Genval recommendations and the usefulness of a short trial of proton pump inhibitor(PPI) in the initial management and maintenance treatment of gastroesophageal reflux disease(GERD)patients. METHODS:Five hundred and seventy seven patients with heartburn were recruited.After completing a psychometric tool to assess quality of life(PGWBI)and a previously validated GERD symptom questionnaire (QUID),patients were grouped into those with esophagitis(EE,n=306)or without mucosal damage (NERD,n=271)according to endoscopy results. The study started with a 2-wk period of high dose omeprazole(omeprazole test);patients responding to this PPI test entered an acute phase(3 mo)of treatment with any PPI at the standard dose.Finally,those patients with a favorable response to the standard PPI dose were maintained on a half PPI dose for a further 3-mo period. RESULTS:The test was positive in 519(89.9%)patients,with a greater response in EE patients(96.4%) compared with NERD patients(82.6%)(P=0.011). Both the percentage of completely asymptomatic patients,at 3 and 6 mo,and the reduction in heartburn intensity were significantly higher in the EE compared with NERD patients(P<0.01).Finally,the mean PGWBI score was significantly decreased before and increased after therapy in both subgroups when compared with the mean value in a reference Italian population. CONCLUSION:Our study confirms the validity of the Genval guidelines in the management of GERD patients. In addition,we observed that the overall response to PPI therapy is lower in NERD compared to EE patients.Fabio Pace Gabriele Riegler Annalisa de Leone Patrizia Dominici Enzo Grossi the EMERGE Study Group 2011World Journal of Gastroenterology2011,17,9:5
12Colorectal cancer and 18FDG-PET/CT:What about adding the T to the N parameter in loco-regional staging?显示文摘AIM:To evaluate whether FDG-positron emission tomography(PET)/computed tomography(CT)may be an accurate technique in the assessment of the T stage in patients with colorectal cancer.METHODS:Thirty four consecutive patients(20 men and 14 women;mean age:63 years)with a histologically proven diagnosis of colorectal adenocarcinoma and scheduled for surgery in our hospital were enrolled in this study.All patients underwent FDG-PET/CT preoperatively.The primary tumor site and extent were evaluated on PET/CT images.Colorectal wall invasion was analysed according to a modified T classification that considers only three stages(≤T2,T3,T4).Assessment of accuracy was carried out using 95%confidence intervals for T.RESULTS:Thirty five/37(94.6%)adenocarcinomas were identified and correctly located on PET/CT images.PET/CT correctly staged the T of 33/35 lesions identified showing an accuracy of 94.3%(95%CI:87%-100%).All T1,T3 and T4 lesions were correctly staged,while two T2 neoplasms were overstated as T3.CONCLUSION:Our data suggest that FDG-PET/CT may be an accurate modality for identifying primary tumor and defining its local extent in patients with colorectal cancer.Pier Paolo Mainenti Delfina Iodice Sabrina Segreto Giovanni Storto Mario Magliulo Giovanni Domenico De Palma Marco Salvatore Leonardo Pace 2011World Journal of Gastroenterology2011,17,11:5
13The first record of fossil Vitaceae wood from the Southern Hemisphere, a new combination for Vitaceoxylon ramunculiformis, and reappraisal of the fossil record of the grape family (Vitaceae) from the Cenozoic of Australia显示文摘Austrovideira dettmannae 情报。与 sp。nov。从早渐新世御夫星座,在中央 Queensland 的弗洛拉是从南部的半球描述的第一根石块 Vitaceae 木头。新联合,为一根北半球石块木头的步与 Rozefelds 也是的 Stafylioxylon ramunculiformis (Poole 与威尔金森) 求婚了。有有容器的二个直径班的 Vitaceoxylon 第二等的木部的 Austrovideira 和 Stafylioxylon 份额,宽容器形成光线的链,很宽、高的光线,贫乏的 paratracheal 实质和有中隔的纤维的通常独居的、狭窄的容器。Austrovideira 在梯状的 intervessel 坑和 homocellular 光线专门爬地的房间创作了不同于 Vitaceoxylon。特征的这联合在 AmpelocissusVitis clade,和一个清楚地成层的韧皮部被看见,纤维乐队与所有另外的轴的元素轮流出现,很快向周皮膨胀的韧皮部光线被限制为 Parthenocissus 和 Vitis。Stafylioxylon 与 Austrovideira 分享梯状的 intervessel 坑的存在,但是它在两篇光线作文不同于那个类并且吠叫解剖,它缺乏一个成层的韧皮部。这些石块木头类证明在 Vitaceae 的 lianescent 习惯被建立由在北半球并且由在南部的半球的渐新世始新世。花粉和种子石块记录证明 Vitaceae 在澳大利亚由始新世并且石块种子建议家庭此时放射了。有二种子 taxa 和石块木头(Austrovideira ) 的渐新世御夫星座植物群提供澳大利亚的放射的进一步的证据。石块证据,为家庭建议重要 Gondwanic 历史。Andrew C. Rozefelds Marcelo R. Pace 2018Journal of Systematics and Evolution2018,56,4:4
14基于TOF-3D相机单视角物体表面重建研究显示文摘物体的三维重建是计算机视觉、虚拟现实、人工智能等领域研究的重点和难点,为了能够更好的重建物体三维表面,文中提出了一种改进的Delaunay三角剖分算法。此算法与原有的逐点插入Delaunay三角剖分算法的不同在于增加了对三角形边长的约束条件,去除了重建过程中不符合要求的三角形,使其重建效果更加真实可靠。并且基于TOF3D相机拍摄得到的目标物体单视角下的点云数据,结合KNN邻域滤波算法验证了改进的Delaunay算法的可靠性和稳定性。本论文中对单视角下物体表面重建的研究为多视角下物体完整表面3维重建的研究与实现奠定了基础。林正日 孙志斌 Pavel Paces 张志博 2018电子设计工程2018,26,12:4
15Heterogeneity of endoscopy negative heartburn:Epidemiology and natural history显示文摘It has now become clear that only about 40% or less of patients with heartburn and/or regurgitation have esophagitis, and that the majority of them lack visible distal esophageal mucosa breaks. These subjects are referred to as non-erosive gastroesophageal reflux disease (NERD) patients. It has been estimated that in the Western world at least one tenth of the general population has at least weekly heartburn. This proportion seems to be lower in Asia, while prevalence is rapidly increasing. Although it would be extremely useful to have prospective information regarding the fate of such patients, the natural history of NERD is largely unknown, and very few studies in the literature have addressed this issue. These studies are for the greater part old, not well conducted, and suffer from methodological drawbacks including ill-defined entry criteria. However, a review of these studies indicates that a consistent minority of NERD patients may develop erosive disease at an approximate rate of about 10% per year.Fabio Pace Valentina Casini Stefano Pallotta 2008World Journal of Gastroenterology2008,14,34:3
16Holographic optics in planar optical systems for next generation small form factor mixed reality headsets显示文摘Helmet Mounted Displays(HMDs),such as in Virtual Reality(VR),Augmented Reality(AR),Mixed reality(MR),and Smart Glasses have the potential to revolutionize the way we live our private and professional lives,as in communicating,working,teaching and learning,shopping and getting entertained.Such HMD devices have to satisfy draconian requirements in weight,size,form factor,power,compute,wireless communication and of course display,imaging and sensing performances.We review in this paper the various optical technologies and architectures that have been developed in the past 10 years to provide adequate solutions for the drastic requirements of consumer HMDs,a market that has yet to become mature in the next years,unlike the existing enterprise and defense markets that have already adopted VR and AR headsets as practical tools to improve greatly effectiveness and productivity.We focus specifically our attention on the optical combiner element,a crucial element in Optical See-Through(OST)HMDs that combines the see-through scene with a world locked digital image.As for the technological platform,we chose optical waveguide combiners,although there is also a considerable effort today dedicated to free-space combiners.Flat and thin optics as in micro-optics,holographics,diffractives,metasurfaces and other nanostructured optical elements are key building blocks to achieve the target form factor.Bernard C.Kress Maria Pace 2022Light(Advanced Manufacturing)2022,3,4:3
17Feeding Biochar to Cows:An Innovative Solution for Improving Soil Fertility and Farm Productivity显示文摘Addition of biochar produced through thermal decomposition of biomass has been seen as a strategy to improve soils and to sequester carbon(C), but wide scale implementation of the technology requires to devise innovative profitable solutions. To develop biochar utilisation with an integrated system approach, an innovative program was implemented in 2012 on a 53-ha farm in Western Australia to determine the costs and benefits of integrating biochar with animal husbandry and improvement of pastures. Biochar was mixed with molasses and fed directly to cows. The dung-biochar mixture was incorporated into the soil profile by dung beetles.We studied the changes in soil properties over 3 years. Biochar extracted from fresh dung and from the soil to a depth of 40 cm was characterised. A preliminary financial analysis of the costs and benefits of this integrated approach was also undertaken. The preliminary investigation results suggested that this strategy was effective in improving soil properties and increasing returns to the farmer. It was also concluded that the biochar adsorbed nutrients from the cow's gut and from the dung. Dung beetles could transport this nutrient-rich biochar into the soil profile. There was little evidence that the recalcitrant component of the biochar was reduced through reactions inside the gut or on/in the soil. Further research is required to quantify the long-term impact of integrating biochar and dung beetles into the rearing of cows.Stephen JOSEPH Doug POW Kathy DAWSON David R.G.MITCHELL Aditya RAWAL James HOOK Sarasadat TAHERYMOOSAVI Lukas VAN ZWIETEN Joshua RUST Scott DONNE Paul MUNROE Ben PACE Ellen GRABER Torsten THOMAS Shaun NIELSEN Jun YE Yun LIN PAN Genxing LI Lianqing Zakaria M.SOLAIMAN 2015Pedosphere2015,25,5:2
18Influence of capsaicin infusion on secondary peristalsis in patients with gastroesophageal reflux disease显示文摘AIM To determine whether capsaicin infusion could influence heartburn perception and secondary peristalsis in patients with gastroesophageal reflux disease(GERD). METHODS Secondary peristalsis was performed with slow and rapid mid-esophageal injections of air in 10 patients with GERD. In a first protocol, saline and capsaicincontaining red pepper sauce infusions were randomly performed, whereas 2 consecutive sessions of capsaicin-containing red pepper sauce infusions were performed in a second protocol. Tested solutions including 5 m L of red pepper sauce diluted with 15 m L of saline and 20 m L of 0.9% saline were infused into the mid-esophagus via the manometric catheter at a rate of 10 mL /min with a randomized and doubleblind fashion. During each study protocol, perception of heartburn, threshold volumes and peristaltic parameters for secondary peristalsis were analyzed and compared between different stimuli.RESULTS Infusion of capsaicin significantly increased heartburn perception in patients with GERD(P < 0.001), whereas repeated capsaicin infusion significantly reduced heartburn perception(P = 0.003). Acute capsaicin infusion decreased threshold volume of secondary peristalsis(P = 0.001) and increased its frequency(P = 0.01) during rapid air injection. The prevalence of GERD patients with successive secondary peristalsis during slow air injection significantly increased after capsaicin infusion(P = 0.001). Repeated capsaicin infusion increased threshold volume of secondary peristalsis(P = 0.002) and reduced the frequency of secondary peristalsis(P = 0.02) during rapid air injection. CONCLUSION Acute esophageal exposure to capsaicin enhances heartburn sensation and promotes secondary peristalsis in gastroesophageal reflux disease, but repetitive capsaicin infusion reverses these effects.Chih-Hsun Yi Wei-Yi Lei Jui-Sheng Hung Tso-Tsai Liu Chien-Lin Chen Fabio Pace 2016World Journal of Gastroenterology2016,22,45:2
19A method for spatial–temporal forecasting with an application to real estate prices显示文摘R.Kelley Pace Ronald Barry Otis W. Gilley C.F. Sirmans 2000International Journal of Forecasting2000,,2:2
20Mucosal Schwann cell “Hamartoma”:A new entity?显示文摘Schwannoma is a well-described,benign nerve sheath tumor of the soft tissue,but is rare in the gastrointestinal tract.Gastrointestinal schwannomas are often incidentally discovered as small polypoid intraluminal lesions.In this report,we describe the clinicopathologic and immunohistochemical features of a distinctive neural mucosal polyp composed of a diffuse cellular proliferation of uniform bland spindled cells in the lamina propria that entraps the colonic crypts.Immunohistochemical analysis revealed strong and diffuse positivity for the S-100 protein.To avoid confusion of these solitary colorectal polyps containing pure spindled Schwann cell proliferation in the lamina propria with neural lesions that have significant association with inherited syndromes,it is better to use the designation 'mucosal Schwann hamartoma'.Paola Pasquini Andrea Baiocchini Laura Falasca Dante Annibali Guido Gimbo Francesco Pace Franca Del Nonno 2009World Journal of Gastroenterology2009,15,18:2
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