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| 1 | Gastroesophageal reflux: the features in elderlypatients显示文摘AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesophageaI refluxsymptoms, and the results were compared with112 symptomatic younger patients.RESULTS The results of 24-h pH-monitoringand endoscopy showed that the elderly patientshad pathological reflux and reflux esophagitismore frequently than the younger patients.P6rcentage time with pH< 4 in elderly patientswith reflux esophagitis was 32.5% in 24 hours,as compared with 12.9% in the younger patientswith reflux esophagitis (P < 0 .05 ). The elderlypatients with reflux esophagitis have longerP6riOds of acid reflux in both upright and Supinepositions than the younger patients. Endoscopyshowed that 20 .8% of elderIy patients had grade Ⅲ / Ⅳ esophagitis, whereas only 3.4% ofyounger patients had grade Ⅲ/ Ⅳ esophagitis(P < 0.002 ). Percentages of grades Ⅰ /Ⅱesophagitis in the two groups were 12.5% and26. 5%, respectiveIy (P< 0. 002 ).CONCLUSION Elderly patients, as comparedwith younger patients, have more severegastroesophageal reflux and esophageal lesions.The incompetence of lower esophageal sphincter and the presence of hiataI hernia may beimportant factors leading to the difference in incidence and severity of reflux esophagitisbetween elderly and younger patients. | Huang X Zhu HM Deng CZ Porro GB Sangaletti O Pace F | 1999 | World Journal of Gastroenterology1999，5，5： | 12 |
| 2 | Pathogenetic factors affecting gastroesophageal refluxin patients with esophagitis and concomitant duodenal ulcer:a multivariate analysis显示文摘Pathogeneticfactorsafectinggastroesophagealrefluxinpatientswithesophagitisandconcomitantduodenalulcer:amultivariateanalysisZH... | Zhu, HM Huang, X Deng, CZ Porro, GP Pace, F Sangaletti, O | 1998 | World Journal of Gastroenterology1998，4，2： | 2 |
| 3 | Progress in pleckstrin homology domain study显示文摘 | Deng YC Yao LB Su CZ | | 生命科学0，，： | 1 |
| 4 | Chronological sequence of the early Pleistocene Gigantopilhecus faunas from cave sites in the Chongzuo,Zuojiang River area,South China显示文摘 | Jin CZ Wang Y Deng CL | 2014 | Quaternary International2014，354，： | 1 |
| 5 | Transcriptional acti-vation of cellular oncogenes fos, jun, and myc by human cy-tomegalovirus显示文摘 | Boldogh I AbuBakar S Deng CZ | 1991 | J Virol1991，65，3： | 1 |
| 6 | Chronological sequence of the early Pleistocene Gigantopithecus faunas from cave sites in the Chongzuo, Zuojiang River area, South China显示文摘 | Jin CZ Wang Y Deng CL | 2014 | Quaternary International2014，354，： | 1 |
| 7 | Transcriptional activation ofcellular oncogenes fos, jun, and myc by human cytomegalovirus 显示文摘 | Boldogh I AbuBakar S Deng CZ | 1991 | Journal of virology1991，65，3： | 1 |
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