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| 1 | 栽培稻种间近等基因系杂种育性遗传及其基因定位显示文摘用粳型亚洲栽培稻品种 WAB56- 1 0 4与来自种间回交组合 WAB56- 1 0 4 /CG1 4∥ WAB56- 1 0 4 ///WAB56- 1 0 4的3个栽培稻种间近等基因系杂交、回交 ,对 3个 BC1F1群体的花粉及小穗育性遗传研究表明 ,育性遗传符合单位点孢子体 -配子体互作模型 ,来自非洲栽培稻的不育基因在与相同位点的亚洲栽培稻等位基因互作时 ,导致携带亚洲栽培稻等位基因的雌雄配子败育 ,而形成花粉及小穗的半不育 ,但本研究的 3个组合中 ,并未导致所有携带亚洲栽培稻等位基因的雌配子完全败育 ,其作用介于配子消除与花粉灭杀之间。用微卫星标记对这 3个群体的育性基因定位表明 ,它们都位于第 6染色体短臂末端 ,但 WAB450 - 2、WAB450 - 8携带的不育位点与紧密连锁的微卫星标记 RM1 90、RM1 33共分离 ,且很可能与 S1等位 ,而WAB450 - 7的不育基因则与位于相邻区间的 RM2 53呈松散连锁 ,可能与 WAB450 - 2、WAB450 - | 陶大云 徐鹏 李静 杨友琼 周家武 胡凤益 Monty P.JONES | 2003 | 中国水稻科学2003,17,1: | 5 |
| 2 | A comparison of tracer kinetic models for T1‐weighted dynamic contrast‐enhanced MRI: Application in carcinoma of the cervix显示文摘 | Stephanie B.Donaldson Catharine M. L.West Susan E.Davidson Bernadette M.Carrington GillianHutchison Andrew P.Jones Steven P.Sourbron David L.Buckley | 2010 | Magn. Reson. Med2010,,3: | 2 |
| 3 | Redox compartmentalization and cellular stress显示文摘 | D. P.Jones Y.‐M.Go | 2010 | Diabetes, Obesity and Metabolism2010,,: | 1 |
| 4 | Metabolism of [U‐<sup>13</sup>C<sub>5</sub>]Glutamine in Cultured Astrocytes Studied by NMR Spectroscopy: First Evidence of Astrocytic Pyruvate Recycling显示文摘 | U.Sonnewald N.Westergaard P.Jones A.Taylor H. S.Bachelard A.Schousboe | 2002 | Journal of Neurochemistry2002,,6: | 1 |
| 5 | Identifying High Risk Groups and Quantifying Absolute Risk of Cancer After Kidney Transplantation: A Cohort Study of 15 183 Recipients显示文摘 | A. C.Webster J. C.Craig J. M.Simpson M. P.Jones J. R.Chapman | 2007 | American Journal of Transplantation2007,,9: | 1 |
| 6 | Systematic review and meta‐analysis of follow‐up after hepatectomy for colorectal liver metastases显示文摘 | R. P.Jones R.Jackson D. F. J.Dunne H. Z.Malik S. W.Fenwick G. J.Poston P.Ghaneh | 2012 | Br J Surg2012,,4: | 1 |
| 7 | Influence of biological sex and exercise on murine cardiac metabolism显示文摘Although the structural and functional effects of exercise on the heart are well established,the metabolic changes that occur in the heart during and after exercise remain unclear.In this study,we used metabolomics to assess time-dependent changes in the murine cardiac metabolome following 1 session of treadmill exercise.After the exercise bout,we also recorded blood lactate,glucose,and ketone body levels and measured cardiac mitochondrial respiration.In both male and female mice,moderate-and high-intensity exercise acutely increased blood lactate levels.In both sexes,low-and moderate-intensity exercise augmented circulating 3-hydroxybutryrate levels immediately after the exercise bout;however,only in female mice did high-intensity exercise increase 3-hydroxybutyrate levels,with significant increases occurring 1 h after the exercise session.Untargeted metabolomics analyses of sedentary female and male hearts suggest considerable sex-dependent differences in basal cardiac metabolite levels,with female hearts characterized by higher levels of pantothenate,pyridoxamine,homoarginine,tryptophan,and several glycerophospholipid and sphingomyelin species and lower levels of numerous metabolites,including acetyl coenzyme A,glucuronate,gulonate,hydroxyproline,prolyl-hydroxyproline,carnosine,anserine,and carnitinylated and glycinated species,as compared with male hearts.Immediately after a bout of treadmill exercise,both male and female hearts had higher levels of corticosterone;however,female mice showed more extensive exercise-induced changes in the cardiac metabolome,characterized by significant,time-dependent changes in amino acids(e.g.,serine,alanine,tyrosine,tryptophan,branched-chain amino acids)and the ketone body 3-hydroxybutyrate.Results from experiments using isolated cardiac mitochondria suggest that high-intensity treadmill exercise does not acutely affect respiration or mitochondrial coupling;however,female cardiac mitochondria demonstrate generally higher adenosine diphosphate sensitivity compared with male cardiac mitochondria.Collectively,these findings in mice reveal key sex-dependent differences in cardiac metabolism and suggest that the metabolic network in the female heart is more responsive to physiological stress caused by exercise. | Kyle Fulghum Helen E.Collins Steven P.Jones Bradford G.Hill | 2022 | Journal of Sport and Health Science2022,11,4: | 1 |
| 8 | Randomized clinical trial of the effects of preoperative and postoperative oral nutritional supplements on clinical course and cost of care显示文摘 | F.Smedley T.Bowling M.James E.Stokes C.Goodger O.O’Connor C.Oldale P.Jones D.Silk | 2004 | Br J Surg2004,,: | 1 |
| 9 | Cormectionist approach PID autotming显示文摘 | Ruono P.J Fleming P.Jones | | 0,,03: | 1 |
| 10 | 恢复红树林:热带发展中国家沿海管理的一种潜在手段显示文摘红树林生态系统是热带地区沿海的主要生境,它直接或间接地为人们提供了生活物资和商业鱼产品。然而,发展中国家红树林生态系统正在受到威胁,那里的红树林正为了满足人类各种活动而被砍伐。据估计,现在亚太地区每年损失1%的红树林面积,有些地区已经失去了70%的原始红树林生境。由于不断的干扰、土地条件的改变和有限的扩种,自然恢复过程很缓慢。本文讨论了把恢复红树林作为管理沿海生态系统的一个潜在手段问题。我们简要地分析了红树林和渔业的关系,概述了评价恢复红树林行动的生态系统方法。过去发展中国家有关恢复红树林的项目只是着重再植树的各种方法,几乎不注重评价生态系统功能是否恢复。然而,恢复红树林项目的目的应该是积极地促进其自然群体的结构和自我维持的功能恢复(在自然变动范围内)。这个目标需要:①明确自然状态,包括维持自然基础的关键生物、维持鱼种的群落结构和食物网;②发展恢复关键生物的生物技术;③对项目能否长期保持成功进行评价。由于恢复被看作是维持发展中国家沿海生态系统健康的重要手段,所以应该优先考虑如何把恢复项目和对它的评价与沿海管理计划结合起来。 | Ursula L.Kaly Geoffrey P.Jones 王燕 | 1998 | 人类环境杂志1998,27,8: | 0 |
| 11 | 用键合相硅胶的离子色谱法测定铂族金属和金的氯络合物显示文摘采用硅基相的阴离子交换和离子相互作用法,研究了Au(Ⅲ)、Ir(Ⅳ)、Ir(Ⅲ)、Os(Ⅳ)、Pd(Ⅱ)、Pt(Ⅳ)、Rh(Ⅲ)和Ru(Ⅲ)氯络合物的离子色谱。体系中不存在氯化物或其浓度很低,且其pH值高,则能够使用钢制液相色谱设备。采用阴离子交换法时,Ir(Ⅳ)、Ir(Ⅲ)、Os(Ⅳ)和Pt(Ⅳ)具有好的稳定的色谱图,除Ir(Ⅳ)由于样品溶液不稳定外,其它离子有线性的校正曲线。检测限分别为Ir(Ⅲ)5ng/mL、Os(Ⅳ)10ng/mL和Pt(Ⅳ)2ng/mL。采用离子相互作用法不是很成功的,仅Au(Ⅲ)和Pd(Ⅱ)能得到稳定的色谱图。虽然校正曲线稍有弯曲,但尚能接受。Au(Ⅲ)和Pd(Ⅱ)的检测限分别为10和30ng/mL。 | P.Jones 巫忆陵 | 1990 | 湿法冶金1990,9,3: | 0 |
| 12 | In situ measurement of ECM rheology and microheterogeneity in embedded and overlaid 3D pancreatic tumor stroma co-cultures via passive particle tracking显示文摘Tumor growth is regulated by a diverse set of extraellular infuences,including paracrine crosstalk with stromal partners,and biophysical interactions with surrounding cells and tissues.Studies elucidating the role of physical force and the mechanical properties of the extracellular matrix(ECM)itself as regulators of tumor growth and invasion have been greatly catalyzed by the use of in ritro three-dimensional(3D)tumor models.These systems provide the ability to systematically isolate,manipulate,and evaluate impact of stromal components and extracellular mechanics in a platform that is both conducive to imaging and biologically relevant.However,recognizing that mechanoregulatory crosstalk is bi-directional and fully utilizing these models requires complementary methods for in situ measurements of the local mechanical environment.Here,in 3D tumor/fbroblast co-culture models of pancreatic canocer,a discase characterized by its prominent stromal involvement,we evaluate the use of particle-tracking microrhoology to probe dynamic mechanical changes.Using videos of fuorescently labeled polystyrene micro-spheres embedded in ollagen I ECM,we measure spatiotemporal changes in the Brownian motion of probes to report local ECM shear modulus and microheterogeneity.This approach reveals st ffening of collagen in fibroblast co-cultures relative to cultures with cancer cells only,which exhibit degraded ECM with heterogeneous microstructure.We further show that these effects are dependent on culture geometry with contrast ing behavior for embedded and overlay cultures.In addition to potential application to screening stroma targeted therapeutics,this work also provides insight into how the compoition and plating geometry impact the mechanical propertios of 3D cell cultures that are increasingly widey used in cancer biology. | Dustin P.Jones William Hanna Gwendolyn M.Cramer Jonathan P.Celli | 2017 | Journal of Innovative Optical Health Sciences2017,,6: | 0 |