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| 1 | Atrophic gastritis: Risk factor for esophageal squamous cell carcinoma in a Latin-American population显示文摘AIM: To study the association between atrophic gastritis (AG) and esophageal squamous cell carcinoma (ESCC) in a Latin-America population. METHODS: A case-control study was performed at two reference Brazilian hospitals including patients diagnosed with advanced ESCC and dyspeptic patients who had been subjected to upper gastrointestinal endoscopy, with biopsies of the gastric antrum and body.All cases with ESCC were reviewed by a single pathologist, who applied standard criteria for the diagnosis of mucosal atrophy, intestinal metaplasia, and dysplasia, all classified as AG. The data on the patients' age, sex, smoking status, and alcohol consumption were collected from clinical records, and any missing information was completed by telephone interview. The association between AG and ESCC was assessed by means of univariate and multiple conditional logistic regressions. RESULTS: Most patients were male, and the median age was 59 years (range: 37-79 years) in both the ESCC and control groups. Univariate analysis showed that an intake of ethanol greater than 32 g/d was an independent risk factor that increased the odds of ESCC 7.57 times (P = 0.014); upon multiple analysis, alcohol intake of ethanol greater than 32 g/d exhibited a risk of 4.54 (P = 0.081), as adjusted for AG and smoking. Smoking was shown to be an independent risk factor that increased the odds of ESCC 14.55 times (P = 0.011) for individuals who smoked 0 to 51 packs/year and 21.40 times (P = 0.006) for those who smoked more than 51 packs/year. Upon multiple analyses, those who smoked up to 51 packs/year exhibited a risk of 7.85 (P = 0.058), and those who smoked more than 51 packs/ year had a risk 11.57 times higher (P = 0.04), as adjusted for AG and alcohol consumption. AG proved to be a risk factor that increased the odds of ESCC 5.33 times (95%CI: 1.55-18.30, P = 0.008) according to the results of univariate conditional logistic regression. CONCLUSION: There was an association by univariate conditional logistic regression between AG and ECSS in this sample of Latin-American population. | Emiliano de Carvalho Almodova Walmar Kerche de Oliveira Lucas Faria Abraho Machado Juliana Rigotto Grejo Thiago Rabelo da Cunha Wagner Colaiacovo Erika Veruska Paiva Ortolan | 2013 | World Journal of Gastroenterology2013，19，13： | 5 |
| 2 | Microspectroscopic detection of local conducting areas generated by electric-pulse- induced phase transition in VO2 films 显示文摘 | Lee L S Ortolan M Schade U | 2007 | Applied Physics Let- ters2007，91，13： | 1 |
| 3 | De-hairing activity of extracellular proteases produced by keratinolyric bacteria显示文摘 | RIFFEL A ORTOLAN S BANNDELLI A | 2003 | Journal of Chemical Technology and Biotechnology2003，78，： | 1 |
| 4 | Evaluation of adapti- ve/nonadaptive filtering and wavelet transform techniques for noise reduction in EMG mobile acquisition equipment 显示文摘 | Ortolan RL Mori RN Pereira RR etc | 2003 | IEEE Transact- ions on Neural Systems and Rehabilitation2003，11，1： | 1 |
| 5 | Upper gastrointestinalhistopathological findings in children and adolescents withnonulcer dyspepsia with Helicobacter pylori infection显示文摘 | Carvalho MA Machado NC Ortolan EVP | 2012 | J PediatrGastroenterol Nutr2012，55，5： | 1 |
| 6 | Evaluation of adaptive/nonadaptive filtering and wavelet transform techniques for noise reduction in EMG mobile acquisition equipment显示文摘 | ORTOLAN R L MORI R N PEREIRA R R | 2003 | IEEE Trans on Neural Systems and Rehabilitation Engineering2003，11，1： | 1 |
| 7 | Functional role and prognostic significance of CD157 in ovarian carcinoma显示文摘 | Ortolan E Arisio R Morone S | 2010 | J Natl Cancer Inst2010，102，15： | 1 |
| 8 | CD157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome显示文摘 | Ortolan E Giacomino A Martinetto F | 2014 | Oncotarget2014，5，15： | 1 |
| 9 | Giant sacral schwannoma:a case report显示文摘 | Ortolan EG Sola CA Gruenberg MF | 1996 | Spine1996，21，4： | 1 |
| 10 | Effect of extruded wheat flour and pre-gelatinized cassava starch on process and quality pkrameters of French-type bread elaborated from frozen dough显示文摘 | Ortolan F | 2015 | Food Research International2015，，76： | 1 |
| 11 | Anti-den- tine atibodies with root resorption during orthodontic treat- ment 显示文摘 | Ramos Sde P Ortolan GO Dos Santos LM | 2011 | Eur J Orthod2011，33，5： | 1 |
| 12 | Low-density wireless sensor networks for localization and tracking in critical environments显示文摘 | Cenedese G Bertinato Ortolan M | 2010 | IEEE Transactions on Vehicular Technology2010，59，6： | 1 |
| 13 | Microscopic, Morphometric and Ultrastructural Analysis of Anastomotic Healing in the Intestine of Normal and Diabetic Rats显示文摘 | E. Ortolan C. Spadella C. Caramori J. Machado E. Gregorio K. Rabello | 2008 | Exp Clin Endocrinol Diabetes2008，，04： | 1 |
| 14 | De-hairing activity of extracellular proteases produced by keratinolytic bacteria 显示文摘 | Riffel A Ortolan S Brandelli A | 2003 | Journal of Chemical Technology and Biotechnology2003，78，： | 1 |
| 15 | Anti-dentine an- tibodies with root resorption during orthodontic treatment显示文摘 | Ramos Sde P Ortolan GO Dos Santos LM | 2011 | Eur J Orthod2011，33，5： | 1 |
| 16 | Giant sacral schwan- noma:A case report显示文摘 | Ortolan EG Sola CA Gruenberg MF | 1996 | Spine1996，21，4： | 1 |
| 17 | Influence of tumor necrosis factor α inhibitors on testicular function and semen in spondyloarthritis patients显示文摘 | Roberta Ramonda Carlo Foresta Augusta Ortolan Alessandro Bertoldo Francesca Oliviero Mariagrazia Lorenzin Damiano Pizzol Leonardo Punzi Andrea Garolla | 2013 | Fertility and Sterility2013，，： | 1 |
| 18 | Cytofluorimetric identification of two populations of double positive (CD4^+, CD8^+) T lymphoeytes in human peripheral blood 显示文摘 | Ortolan C Forti E Radin E | 1993 | Biochem Biophys Res Commun1993，191，2： | 1 |
| 19 | Interaction of a gravitational wave with electromagnetic currents显示文摘 | P. Fortini C. Gualdi A. Ortolan | 1991 | Il Nuovo Cimento B Series1991，，4： | 1 |
| 20 | Uppergastrointestinal histopathological findings in children and adoles-cents with nonulcer dyspepsia with Helicobacter pylori infection显示文摘 | Mary Assis Carvalho Nilton Carlos Machado Erika VeruskaPaiva Ortolan Maria Aparecida Marchesan Rodrigues | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，55，： | 1 |
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