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1基于UMU互动平台“互联网+移动学习”探究显示文摘以目前流行的一款教育类APP——UMU互动学习平台为例,分别从教师和学生的角度分析该平台教学过程的实现方式。利用该平台,简化了微课的创建过程,强化了学生的主体地位,大数据分析为教师的教学工作提供了有力支撑,线上线下学习更加紧密结合。通过探究'互联网+'时代新型移动学习方式,激发了学生的学习兴趣,提高了教育教学质量。李晓霞 Mary Augusta Brazelton 马艺洁 2019实验技术与管理2019,36,4:18
2Improved sexual behavior in male rats treated with a Chinese herbal extract: hormonal and neuronal implications显示文摘瞄准:为了调查一篇摘录的影响,在成年雄的老鼠的性行为上从五中国药用的植物获得了。方法:摘录被口头的 gavage 在 30, 60 和 120 mg/kg 的剂量管理,尖锐地(一次,在交配测试前的 45 min ) 或长期地代替(为 10 天的日报) 在里面性有势力和性懒惰 / 无力的老鼠。性行为, luteinizing 荷尔蒙(LH ) 的浆液层次和睾丸激素(T) 在对待的老鼠并且与收到车辆的控制相比被评估。中央 dopaminergic neurotransmission 上的摘录的效果用一种微分离技术在原子核 accumbens 被估计。结果:在里面性有势力老鼠,尖锐并且有摘录的长期的处理在 30 和 60 mg/kg 开了的潜水艇减少了山潜伏和插入潜伏。在懒惰 / 无力的老鼠,在 60 mg/kg 的剂量的尖锐地管理的摘录弄短而潜水艇长期地在 30 和 60 mg/kg 的剂量管理了,射精潜伏减少了山,插入和射精潜伏,也增加装并且射精老鼠的百分比。显著地在 60 mg/kg 开的摘录增加了 LH 和敏锐的 T 追随者和长期的管理和增加的 3,4-dihydroxyphenylacetic 酸在原子核 accumbens 铺平的潜水艇,在尖锐管理以后的 30 min。结论:改进在食欲并且在与摘录对待的雄的老鼠观察的性行为的 consummatory 部件能与中央 dopaminergic 系统的激活同时被归功于到增加的浆液 T 水平。Paola Zanoli Augusta Benelli Manuela Zavatti Marianna Rivasi Claudia Baraldi Mario Baraldi 2008Asian Journal of Andrology2008,10,6:6
3Tissue-specific expression of GFP reporter gene in germline driven by GATA-2 promoter and enhancers in zebrafish显示文摘GATA-2, a transcription factor, is expressed in several types of blood cells and in the central nervous system (CNS), and regulates the differentiation of these cells. We have obtained five zebrafish transgenic germlines that carry and express the green fluorescent protein (GFP) gene ligated to various 5’ flanking sepuences of zebrafish GATA-2 gene. The spatial pattern of GFP expression varies, mainly depending on which regulatory sequence is used, among the germlines. In some of the germlines, the expression of GFP is restricted to the CNS and the enveloping layer (EVL) cells, while in some other lines GFP is observed only in the CNS. it is noted that the intensity of GFP in the transgenic fish remain unchanged after a six-generation passage of the transgenes. The transgenic fish could find its uses in the future in generating tissue-specific, even cellspecific mutant fish and in functional study of related genes through transgenesis.MENG Anming & LIN Shuo1. Laboratory of Developmental Biology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China 2. Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA 2000Chinese Science Bulletin2000,45,1:2
4Role of apoptosis resistance in immune evasion and metastasis of colorectal cancer显示文摘The host immune system functions as a guardian against tumor development. It has been demonstrated that cytotoxic T lymphocyte (CTL)-mediated cytotoxic pathways function to inhibit or delay human colorectal cancer development. However, the host anti-tumor immune responses also 'edit' the tumor and select for more aggressive variants, resulting in immune evasion and tumor escape. Fas is a death receptor that mediates one of the major cytotoxic effector mechanisms of the CTLs. Fas is highly expressed in normal human colon epithelial cells but is frequently silenced in colorectal carcinoma, especially in metastatic colorectal carcinoma, suggesting that loss of Fas expression and function may be an immune evasion and tumor escape mechanism. In addition, recent studies indicated that Fas also mediates cellular proliferation signaling pathways to promote tumor development. Therefore, the death receptor Fas may not only transduce death signals to suppress tumor development but also activate cellular proliferation and the migration process to promote tumor growth and progression. Thus, understanding the mechanisms by which the Fas receptor and its associated protein complex transduces the death and survival signals may identify molecular targets for the development of therapeutic strategy to enhance the Fas-mediated death signals to increase the efficacy of cancer immunotherapy.Kebin Liu, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, United States 2010World Journal of Gastrointestinal Oncology2010,2,11:2
5External validation of a classification for methylene blue magnification chromoendoscopy in premalignant gastric lesions显示文摘Miguel Areia Pedro Amaro Mário Dinis-Ribeiro Maria Augusta Cipriano Carol Marinho Altamiro Costa-Pereira Carlos Lopes Luís Moreira-Dias José Manuel Rom?ozinho Hermano Gouveia Diniz Freitas Maximino Correia Leit?o 2008Gastrointestinal Endoscopy2008,,7:1
6The Influence of the In- terneton the PsychosocialPredictors of Collective Action 显示文摘AUGUSTA I A PATRIZIA M 2013Journal of Community & Applied Social Psychology2013,23,:1
7Implantation of recombinant human bone morphogenetie proteins with biomaterial carriers: A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model显示文摘Uludag H D'Augusta D Golden J 2000J Biomed Mater Res2000,50,2:1
8An investigation of relationships between communication style and leadermember显示文摘Augusta C Y Sandra H William P G 2002Journal of Communication Management2002,6,3:1
9PI 3-k signaling pathway suppresses PMA-induced expression of p21 WAF1/Cip1 in hu man leukemia cell 显示文摘Augustas P Jurate S Grazina T 2007Molecular and Cellular Biochemistry2007,302,12:1
10Synthesis,Properties and Biodegradability of Polyester Based on 1,3-Propanediol 显示文摘Witt U Muller R J Augusta J 1994Macromol Chem Phys1994,195,:1
11Multidimensional data modeling for location-based services显示文摘Christian S Jensen Augustas Kligys Torben Bach Pedersen Igor Timko The International Journal on Very Large Data Bases Issue0,13,1:1
12Synthesis, properties and biodegradability of polyesters based on 1,3-propanediol显示文摘WITT U MUELLER R J AUGUSTA J 1994Macromolecular Chemistry and Physics1994,195,2:1
13Synthesis,properties and biodegradability of polyesters based on 1,3-propanediol显示文摘Witt U Müller R J Augusta J 1994Macromolecular Chemistry and Physics1994,195,2:1
14Dete-rmination of stanozolol in tablets by derivative ultraviolet spectrophotometry and high-performance liquid chroma-tography显示文摘Vanni Cavrini A Maria Di Pietra M Augusta Raggi 1987ANALYST(London)1987,112,12:1
15Enantiomeric separation of fluoxetine and norfluoxetine in plasma and serum samples with high detection sensitivity capillary electrophoresis显示文摘Claudia Desiderio Serge Rudaz Maria Augusta Raggi 0,,17:1
16Adaptation of forest ecosystems to air pollution and climate change: a global assessment on research priorities 显示文摘Serengil Y Augustaitis A Bytnerowiez A etal 2011iForest-Biogeoseienees and Forestry2011,4,4:1
17Implantation of recombinant human bone morphogenetic proteins with biomaterials carriers:A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model显示文摘Uludag H D'Augusta D 2000J Biomed Mater Res2000,50,2:1
18Methanogenic pathways of coal-bed gas in the Powder River Basin, United States: The geologic factor显示文摘Romeo M. Flores Cynthia A. Rice Gary D. Stricker Augusta Warden Margaret S. Ellis 2008International Journal of Coal Geology2008,,1:1
19Tentorial Posterior Fossa Meningioma显示文摘Paulo Henrique Piers de Angular Welling son Silva Pavia Pedro Augusta De Santana 2009Neurosurg Q2009,19,:1
20Urban wastewater treatment technologies and the implementation of discharge standards in developing countries显示文摘Marcos Van Speding Carlos Augusta de Lenmos Chernicharo 2002Urban Water2002,20,4:1
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