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| 1 | DNA G-quadruplex and its potential as anticancer drug target显示文摘G-quadruplex secondary structures are four-stranded globular nucleic acid structures form in the specific DNA and RNA G-rich sequences with biological significance such as human telomeres,oncogene-promoter regions,replication initiation sites,and 5′and 3′-untranslated(UTR)regions.The non-canonical G-quadruplex secondary structures can readily form under physiologically relevant ionic conditions and are considered to be new molecular target for cancer therapeutics.This review discusses the essential progress in our lab related to the structures and functions of biologically relevant DNA G-quadruplexes in human gene promoters and telomeres,and the opportunities presented for the development of G-quadruplex-targeted smallmolecule drugs. | ONEL Buket LIN Clement YANG Dan Zhou | 2014 | Science China Chemistry2014，57，12： | 3 |
| 2 | Intermittent intravenous cyclophosphamide arrests progression of the renal chronicity index in childhood systemic lupus erythematosus 显示文摘 | Lehman T J Onel K | 2000 | J Pediatr2000，136，2： | 1 |
| 3 | Bupivacaine extend- ed-release liposome injection for prolonged postsurgical analgesia in patients undergoing hemorrhoidectomy:a mul- ticenter, randomized, double-blind, placebo-controlled trial显示文摘 | Gorfine SR Onel E Patou G | 2011 | Dis Colon Rectum2011，54，12： | 1 |
| 4 | Comparison of alphal-adrenoceptor agonists in canine urethral pressure profilometry and abdominal leak point pressure modes 显示文摘 | Brune M Onell AB Gauvin DM | 2001 | J Urol2001，166，： | 1 |
| 5 | A phase 3, randomized, placebo-controlled trial of DepoFoam bupivacaine (ex- tended-release bupivacaine local analgesic) in bunionecto- my显示文摘 | Golf M Daniels SE Onel E | 2011 | Adv Yher2011，28，9： | 1 |
| 6 | Bupivacaine extendedrelease liposome injection for prolonged postsurgical analgesia in patients undergoing hemorrhoidectomy:a multicenter,randomized,double-blind,placebo-controlled trial显示文摘 | Gorfine SR Onel E Patou G | | 0，，12： | 1 |
| 7 | Bupivacaine ex- tended-release liposome injection exhibits a favorable car- diac safety profile 显示文摘 | Bergese SD Onel E Morren M | 2012 | Reg Anesth Pain Med2012，37，2： | 1 |
| 8 | The pharmacokinetics and pharmacodynamics of liposome bupivacaine administered via a single epidural injection to healthy volunteers显示文摘 | Viscusi ER Candiotti KA Onel E | | 0，，06： | 1 |
| 9 | Exploration of a rigid Ice model of frost heave显示文摘 | ONELL K MILLER R D | 1958 | Water Resources Research1958，21，4： | 1 |
| 10 | The efficacy and safety of DepoFoam bupivacaine in patients undergoing bilateral,cosmetic,submuscular augmentation mammaplasty:a randomized,doubleblind,active-control study显示文摘 | Smoot JD Bergese SD Onel E | | 0，，01： | 1 |
| 11 | A two-year observational study assessing the safety of DepoFoam bu- pivacaine after augmentation mammaplasty 显示文摘 | Minkowitz HS Onel E Patronella CK | 2012 | Aesthet Surg J2012，32，2： | 1 |
| 12 | Teacher initiated research: Action research 显示文摘 | Onel Z | 1997 | English Teaching Forum1997，，1： | 1 |
| 13 | MDM2 and prognosis 显示文摘 | Onel K Cordon-Cardo C | 2004 | MOL Cancer Res2004，2，1： | 1 |
| 14 | Identification of a 1-aminocyclopropane-1 -carboxylic acid synthase gene linked to the female(F) locus that enhances female sex expression in cucumber显示文摘 | Trebitsh J Staub J E ONell S D | 1997 | Plant Physiol1997，113，： | 1 |
| 15 | Eadie-Hofstee analysis of red blood cell deformability显示文摘 | Stadnick H Onell R Acker JP | 2011 | Clin Hemorheol Microcirc2011，47，3： | 1 |
| 16 | Recrystallization and particle growth in Al-based SiC particle-reinforced composites显示文摘 | OZDEMIR I TEKMEN C TOPARLI M ONEL K TSUNEKAWA Y | 2003 | Z Metallkd2003，94，： | 1 |
| 17 | Ductility and strength of extruded SiCp/aluminium-alloy composites显示文摘 | Cocen U Onel K | 2002 | Composites Science and Technology2002，62，： | 1 |
| 18 | MDM2 and prognosis显示文摘 | Onel K Cordon - Cordo C | 2004 | Mol Cancer Res2004，2，1： | 1 |
| 19 | Restricted expression and subnuclear localization of the Drosophila gene Dnop5,a member of the Nop/Sik family of the conserved rRNA processing factors显示文摘 | Vorbruggen G Onel S Jackle H | 2000 | Mechanisms Development2000，90，2： | 1 |
| 20 | The effect of forging on the properties of particulate SiC reinforced aluminium alloycomposites 显示文摘 | Ozdemir I Cocen U Onel K | 2000 | Compos Sci Teehnol2000，60，3： | 1 |
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