|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed. | Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost | 2019 | Stroke & Vascular Neurology2019，4，4： | 2 |
| 2 | The prognostic value of cytomegalovirus antigenemia and viremia for the development of cytomrgalovirus disease and survival of AIDS patients显示文摘 | Carton JA Maradona JA de Ona M | 1999 | Med Clan(Bare)1999，113，6： | 1 |
| 3 | Changes in the etiology, incidence and prognosis of acute lower respiratory track infections in human immunodeficiency virus patients显示文摘 | Rafael Perelló Ona Escoda Silvia Camón òscar Miró Marta Casta?eda Asunción Moreno Maria ángeles Marcos Verónica Perea Natalia Alcolea Miquel Sánchez Josep Maria Gatell Esteban Martínez | 2014 | Enfermedades Infecciosas y Microbiologia Clinica2014，，： | 1 |
| 4 | Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease显示文摘 | CHEN M ONA VO LI MW | 2000 | Nat Med2000，6，7： | 1 |
| 5 | The effect Of seminal leukocytes on semen quality in subfertile males with and with-out varicocele 显示文摘 | Tortolero l Duarte Ojeda JM Pamp|ona Casamayor M | 2004 | Arch Esp Urol2004，57，9： | 1 |
| 6 | The influence of elastic moduls mismatch between tooth and post and core restorations on root fracture 显示文摘 | Ona M Akabayashi N Yamazaki T | 2013 | J Int Endod2013，46，1： | 1 |
| 7 | Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model 显示文摘 | Li M Ona VO Guegan C | 2000 | Science2000，288，5464： | 1 |
| 8 | A multi-scale mechanobiological model of in-stent restenosis: deciphering the role of matrix metalloproteinase and extracellular matrix changes显示文摘 | Houman Zahedmanesh Hans Van Oosterwyck Caitríona Lally | 2014 | Computer Methods in Biomechanics and Biomedical Engineering2014，，8： | 1 |
| 9 | Stroke risk after abrupt internal carotid artery sacrifice: accuracy of preoperative assessment with balloon test occlusion and stable xenon-enhanced CT显示文摘 | Linskey ME Jungreis CA Y onas H | 1994 | AJNR Am J Neuroradiol1994，15，5： | 1 |
| 10 | Biological production in a warm temperate evergreen Oak forest of Japan显示文摘 | Kira T Ona Y Hosokawa T | 1978 | JIBP Synthesis1978，18，： | 1 |
| 11 | The Capsid Protein of Infectious Bursal Disease Virus Contains a Functional α4β1 Integrin Ligand Motif显示文摘 | L Delgui Ona A Gutierrez S | 2009 | Virology2009，386，2： | 1 |
| 12 | Binding of the general an- esthetics chloroform and 2,2,2-trichloroethanol to the hy- drophobic core of a four-a-helix bundle protein 显示文摘 | Onas S Johansson K Solt K S | 2003 | Pho- tochemistry and Photobiology2003，77，1： | 1 |
| 13 | Funtional role and therapeutie implications of neuronal Caspase-1 and Caspase-3 in a mouse model of traumatic spinal cord in iury显示文摘 | Li M Ona VO Chen M | 2000 | Neuroscience2000，99，： | 1 |
| 14 | Functional role and therapeutic implications of neuronal caspase-1 and 3 in a mouse model of traumatic spinal cord injury显示文摘 | Li M Ona VO Chen M | 2000 | Neuroscience2000，99，2： | 1 |
| 15 | Arrhythmias during upper gastrointestinal endoscopy 显示文摘 | Mathcw PK Ona FV Damevski K | 1979 | Angiology1979，30，： | 1 |
| 16 | Influence of alveolar support on stress in periodontal structures 显示文摘 | Ona M Wakabayashi N | 2006 | J Dent Res2006，85，12： | 1 |
| 17 | Minoeyeline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease 显示文摘 | CHEN M ONA VO ROBERT J | 2000 | Nat Med2000，6，7： | 1 |
| 18 | The effect ofpH on indole-3- acetic acid (IAA) biosynthesis of Azospirillum brasilense SpT显示文摘 | Ona O Smets I Gysegom P | 2003 | Symbiosis2003，35，13： | 1 |
| 19 | Chitinase levels in rice cultivars correlate with resistance to the sheath blight pathogen Rhizoctonia solani显示文摘 | SHRESTHA C L ONA I MUTHUKRISHNAN S | 2008 | European Journal of Plant Pathology2008，120，1： | 1 |
| 20 | Acne relapse rateand predictors of relapse following treatment with oralisotretinoin显示文摘 | M oral es - Card ona CA Sanchez-Vanegas G | 2013 | Actas Dermosifiliogr2013，104，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员