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| 1 | Predisposing factors, clinical assessment, management and outcomes of agitation in the trauma intensive care unit显示文摘BACKGROUND: Agitation occurs frequently among critically ill patients admitted to the intensive care unit(ICU). We aimed to evaluate the frequency, predisposing factors and outcomes of agitation in trauma ICU. METHODS: A retrospective analysis was conducted to include patients who were admitted to the trauma ICU between April 2014 and March 2015. Data included patient's demographics, initial vitals, associated injuries, Ramsey Sedation Scale, Glasgow Coma Scale, head injury lesions, use of sedatives and analgesics, head interventions, ventilator days, and ICU length of stay. Patients were divided into two groups based on the agitation status.RESULTS: A total of 102 intubated patients were enrolled; of which 46(45%) experienced agitation. Patients in the agitation group were 7 years younger, had significantly lower GCS and sustained higher frequency of head injuries(P<0.05). Patients who developed agitation were more likely to be prescribed propofol alone or in combination with midazolam and to have frequent ICP catheter insertion, longer ventilatory days and higher incidence of pneumonia(P<0.05). On multivariate analysis, use of propofol alone(OR=4.97; 95% CI=1.35–18.27), subarachnoid hemorrhage(OR=5.11; 95% CI=1.38–18.91) and ICP catheter insertion for severe head injury(OR=4.23; 95% CI=1.16–15.35) were independent predictors for agitation(P<0.01).CONCLUSION: Agitation is a frequent problem in trauma ICU and is mainly related to the type of sedation and poor outcomes in terms of prolonged mechanical ventilation and development of nosocomial pneumonia. Therefore, understanding the main predictors of agitation facilitates early risk-stratification and development of better therapeutic strategies in trauma patients. | Saeed Mahmood Omaima Mahmood Ayman El-Menyar Mohammad Asim Hassan Al-Thani | 2018 | World Journal of Emergency Medicine2018，9，2： | 5 |
| 2 | Association of gene variants with susceptibility to type 2 diabetes among Omanis显示文摘AIM:To investigate the association of 10 known common gene variants with susceptibility to type 2diabetes mellitus(T2D)among Omanis.METHODS:Using case-control design,a total of992 diabetic patients and 294 normoglycemic Omani Arabs were genotyped,by an allelic discrimination assay-by-design TaqMan method on fast real time polymerase chain reaction system,for the following gene variants:KCNJ11(rs5219),TCF7L2(rs7903146),CDKAL1(rs10946398),CDKN2A/B(rs10811661),FTO(rs9939609 and rs8050136),IGF2BP2(rs4402960),SLC30A8(rs13266634)CAPN10(rs3792267)and HHEX(rs1111875).T2D patients were recruited from the Diabetes Clinic(n=243)and inpatients(n=749)at Sultan Qaboos Univesity Hospital(SQUH),Muscat,Oman.Adult control participants(n=294)were volunteers from the community and from those visiting Family Medicine Clinic at SQU,for regular medical checkup.The difficulty in recruiting Omani participants with no family history of diabetes was the main reason behind the small number of control participants in this study.Almost all volunteers questioned had a relativewith diabetes mellitus.Inspite of the small number of normoglycemic controls in this study,this sample was sufficient for detection of genes and loci for common alleles influencing T2D with an odds ratio of≥1.3reaching at least 80%power.Data was collected from June 2010 to February 2012.RESULTS:Using binary logistic regression analysis,four gene variants showed significant association with T2D risk:KCNJ11(rs5219,P=5.8×10^(-6),OR=1.74),TCF7L2(rs7903146,P=0.001,OR=1.46),CDKAL1(rs10946398,P=0.002,OR=1.44)and CDKN2A/B(rs10811661,P=0.020,OR=1.40).The fixation index analysis of these four gene variants indicated significant genetic differentiation between diabetics and controls{[KCNJ11(rs5219),P<0.001],[TCF7L2(rs7903146),P<0.001],[CDKAL1(rs10946398),P<0.05],[CDKN2A/B(rs10811661),P<0.05]}.The highest genotype variation%between diabetics and controls was found at KCNJ11(2.07%)and TCF7L2(1.62%).This study was not able to detect an association of T2D risk with gene variants of IGF2BP2(rs4402960),SLC30A8(rs13266634),CAPN10(rs3792267)and HHEX(rs1111875).Moreover,no association was found between FTO gene variants(rs9939609 and rs8050136)and T2D risk.However,T2D risk was found to be significantly associated with obesity(P=0.002,OR=2.22);and with the Waist-to-Hip ratio(n=532,P=1.9×10^(-7),OR=2.4),[among males(n=234,P=1.2×10^(-4),OR=2.0)and females(n=298,P=0.001,OR=6.3)].CONCLUSION:Results confirmed the association of KCNJ11(rs5219),TCF7L2(rs7903146),CDKAL1(rs10946398)and CDKN2A/B(rs10811661)gene variants with susceptibility to T2D among Omani Arabs. | Sawsan Al-Sinani Nicolas Woodhouse Ali Al-Mamari Omaima Al-Shafie Mohammed Al-Shafaee Said Al-Yahyaee Mohammed Hassan Deepali Jaju Khamis Al-Hashmi Mohammed Al-Abri Khalid Al-Rassadi Syed Rizvi Yengo Loic Philippe Froguel Riad Bayoumi | 2015 | World Journal of Diabetes2015，6，2： | 3 |
| 3 | Quality by design: Understanding the formulation variables of a cyclosporine a self- nanoemulsified drug delivery systems by Box - Belmken design and desirability hmction 显示文摘 | Ahmed SZ Omaima AS Mohammed AH | 2007 | lnt J Pharma2007，332，： | 1 |
| 4 | Reaction of eggplant and pepper cultivars to Meloidogyne arenaria and its biological control on eggplant 显示文摘 | I KA IBRAHIM WAFAA T SHAHDA OMAIMA I DAWOOD | 1998 | Alex J Agric Res1998，43，3： | 1 |
| 5 | Mitochondrial distribution, ATP-GSH contents, calcium [Ca 2+ ] oscillation during in vitro maturation of dromedary camel oocytes显示文摘 | Ahmed Sabry S. Abdoon Omaima M. Kandil Shen-Ming Zeng Maosheng Cui | 2011 | Theriogenology2011，，7： | 1 |
| 6 | Racial Disparities in Left Main Stenting: Insights from a Real World Inner City Population显示文摘 | TAMAM MOHAMAD SIDAKPAL S. PANAICH ANAS ALANI APURVA BADHEKA MAITHILI SHENOY BASHAR MOHAMAD EYAS KANAAN OMAIMA ALI MAHIR ELDER THEODORE L. SCHREIBER | 2013 | J. Int. Cardiol2013，，： | 1 |
| 7 | Transforming Growth Factor- β 1 Gene Polymorphism (T29C) in Egyptian Patients with Hepatitis B Virus Infection: A Preliminary Study显示文摘 | Roba M. Talaat Mahmoud F. Dondeti Soha Z. El-Shenawy Omaima A. Khamiss Piero Luigi Almasio | 2013 | Hepatitis Research and Treatment2013，，： | 1 |
| 8 | Quality by design: understanding the formulation variables of acyclosporine a self-nanoemulsified drug delivery systems by Box-Behnken design and desirability function 显示文摘 | AHMED S Z OMAIMA A S MOHAMMED A H | 2007 | Int J Pharm2007，332，12： | 1 |
| 9 | Synthesis of curcumin and ethylcurcumin biocon- jugates as potential antitumor agents显示文摘 | Reem I All-Wabli Omaima M Aboul Wafa Khairia M Youssef | 2012 | Med Chem Res2012，，21： | 1 |
| 10 | Distance Matrix and Markov Chain Based Sensor Localization in WSN显示文摘Applications based on Wireless Sensor Networks(WSN)have shown to be quite useful in monitoring a particular geographic area of interest.Relevant geometries of the surrounding environment are essential to establish a successful WSN topology.But it is literally hard because constructing a localization algorithm that tracks the exact location of Sensor Nodes(SN)in a WSN is always a challenging task.In this research paper,Distance Matrix and Markov Chain(DM-MC)model is presented as node localization technique in which Distance Matrix and Estimation Matrix are used to identify the position of the node.The method further employs a Markov Chain Model(MCM)for energy optimization and interference reduction.Experiments are performed against two well-known models,and the results demonstrate that the proposed algorithm improves performance by using less network resources when compared to the existing models.Transition probability is used in the Markova chain to sustain higher energy nodes.Finally,the proposed Distance Matrix and Markov Chain model decrease energy use by 31%and 25%,respectively,compared to the existing DV-Hop and CSA methods.The experimental results were performed against two proven models,Distance VectorHop Algorithm(DV-HopA)and Crow Search Algorithm(CSA),showing that the proposed DM-MC model outperforms both the existing models regarding localization accuracy and Energy Consumption(EC).These results add to the credibility of the proposed DC-MC model as a better model for employing node localization while establishing a WSN framework. | Omaima Bamasaq Daniyal Alghazzawi Surbhi Bhatia Pankaj Dadheech Farrukh Arslan Sudhakar Sengan Syed Hamid Hassan | 2022 | Computers, Materials & Continua2022，，5： | 0 |
| 11 | Bullying Among School Students in the UAE Society显示文摘The purpose of this study is to research the bullying phenomenon among school students in the UAE society. This is done through showing the extent of prevalence of bullying, the rate of recurrence of bullying incidences, the most widespread forms of bullying among school children in the Emirati society, and finally, the variation with regards to the prevalence and forms of bullying as related to the student’s gender. Therefore, this study aims to probe the prevalence of this phenomenon in schools, and the frequency of bullying cases as well as its forms. For this purpose, a questionnaire was designed and conducted on a sample size of 1,309 students of both genders. The data were later analyzed using descriptive statistical and analytical metrics that are appropriate for the variables’ measurement level, and which achieve the objectives of the study. The study found that a third of the students (33.3%) were involved in bullying incidents. Furthermore, it was found that 14.2% were the party causing the bullying incident, while 19.1% were the party upon which bullying was inflicted. The study also revealed that within school premises the places where bullying was most likely to occur are corridors, and the places which students felt were the least safe are the closed spaces. As for the forms of bullying students are subjected to, offensive name calling or insults came in first place, followed by cyber/online bullying. The young age and smaller size of a student were among the most important motivators for students to bully him/her. It was also found that 32.8% of students who are exposed to bullying respond in a similar manner. The study showed that most of the bullied students (78.4%) know the person doing the bullying, the females being more cognizant of the perpetrator bullying them. Moreover, 40.7% of the students believe that the teachers and other employees are aware of the bullying taking place, female students to a greater extent than males in this regard. In the study sample, the students believe that strong and strict school administration would contribute to stopping the bullying phenomenon. The study additionally concluded a number of recommendations to reduce this phenomenon. | Ahmad Falah Alomosh Salama Mohammad Alrahoomi Moudi Mohamed Hamad Alshamsi Omaima Daham Shaban Alani | 2019 | Psychology Research2019，9，2： | 0 |
| 12 | Colorectal cancer in Alexandria,Egypt;clinical profile,epidemiological characteristics,trend,and survival显示文摘Objective:During the past decades,the incidence of colorectal cancer was increased all around the world.In Egypt,colorectal cancer is the 7th most common cancer.The purpose of this study is to study the problem of colorectal cancer in Alexandria:trend,and survival.Methods:Two methodological strategies were adopted:Record reviewing for estimation of the annual incidence rates of colorectal cancer,and a retrospective cohort study to calculate the 5-year survival rates of colorectal cancer.Results:The annual incidence rates of CRC in Alexandria in 2007-2008 were 6.33 and 6.45 respectively per 100000 mid-year Alexandria population.The overall 5-years cumulative survival rate for CRC cases was 28.0%.Conclusion:This increase in incidence and mortality rates points toward a failed early detection and prevention strategy as well as failure to address lifestyle and dietary challenges of urbanization that affect most of the globe including Egypt. | Moataz M.Abdel-Fattah Omaima G.Yassine | 2010 | 海南医学院学报2010，16，8： | 0 |
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