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| 1 | Kopsia Singapurensis提取物对酸性介质中低碳钢的缓蚀效应(英文)显示文摘The influence of the alkaloid extract of Kopsia singapurensis on the corrosion behavior of mild steel (MS) in 1 mol·L-1 HCl and 1 mol·L-1 H2SO4 was studied using electrochemical techniques, viz., potentiodynamic polarization and AC impedance. The experimental results clearly show that the plant extract effectively inhibits corrosion in both acid media and the inhibition efficiency obtained from the electrochemical techniques is in good agreement. Furthermore, the polarization technique indicates that the extract acts as an anodic type inhibitor in HCl and as a mixed type in H2SO4. Scanning electron microscopy (SEM) was carried out to examine the surface morphological changes of metal specimens in both the inhibited and uninhibited solutions. SEM images show the formation of an adsorbed layer over the metal surface by the inhibitor molecule. The presence of alkaloidal constituents in the plant extract was confirmed by Fourier transform infrared (FTIR) spectroscopy and chemical analysis. | RAJA Pandian Bothi RAHIM Afidah Abdul OSMAN Hasnah AWANG Khalijah | 2010 | 物理化学学报2010，26，8： | 4 |
| 2 | Antioxidant activities of mangrove Rhizophora apiculata bark extracts显示文摘 | Afidah A. Rahim Emmanuel Rocca Jean Steinmetz M. Jain Kassim M. Sani Ibrahim Hasnah Osman | 2007 | Food Chemistry2007，，1： | 1 |
| 3 | Synthesis and Antibacterial Activity of Juglone Derivatives显示文摘 | Daniel Teoh Chuan Tan Hasnah Osman Suriyati Mohamad Azlina Harun Kamaruddin | 2012 | Journal of Chemistry and Chemical Engineering2012，6，1： | 1 |
| 4 | Indole Alkaloids of Alstonia angustifolia var. latifolia as Green Inhibitor for Mild Steel Corrosion in 1 M HCl Media显示文摘 | Pandian Bothi Raja Ahmad Kaleem Qureshi Afidah Abdul Rahim Khalijah Awang Mat Ropi Mukhtar Hasnah Osman | 2013 | Journal of Materials Engineering and Performance2013，，4： | 1 |
| 5 | 3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors显示文摘Dengue is a severe mosquito-borne viral infection causing half a million deaths annually.Dengue virus NS2B/NS3 protease is a validated target for anti-dengue drug design. A series of hitherto unreported 3,5-bis(arylidene)-4-piperidones analogues 4a–4j were synthesized and screened in silico against DENV2 NS2B/NS3 protease to elucidate their binding mechanism and orientation around the active sites. Results were validated through an in vitro DENV2 NS2B/NS3 protease assay using a fluorogenic Boc-Gly-Arg-Arg-AMC substrate. Nitro derivatives of 3,5-bis(arylidene)-4-piperidones(4e and 4j) emerged as promising lead molecules for novel protease inhibitors with an IC50 of 15.22 and16.23 mmol/L, respectively, compared to the standard, panduratin A, having IC50 of 57.28 mmol/L. | Hasnah Osman Nor Hashima Idris Ezatul Ezleen Kamarulzaman Habibah A.Wahab Mohd.Zaheen Hassan | 2017 | Acta Pharmaceutica Sinica B2017，7，4： | 0 |
| 6 | Metabolomics for characterization of gender differences in patients infected with dengue virus显示文摘Objective:To determine the metabolic response associate with dengue infection based on human gender metabolic differences by means of ~1H NMR-spectrometry.Methods:The mid-stream urine collected from both male and female patients diagnosed with dengue fever at Penang General Hospital and fourty-three healthy individuals were analyzed with^1H NMR spectroscopy,followed by chemometric multivariate analysis.NMR signals which highlighted in the OPLS-DA S-plot were further selected and identified using Human Metabolome Database,Chenonix Profiler.Results:The results pointed out that NMR urine profiling was able to capture human gender metabolic differences that are important for the distinction of classes of individuals of similar physiological conditions;infected with dengue.Distinct differences between dengue infected patients versus healthy individuals and subtle differences in male versus female infected with dengue were found to be related to the metabolism of amino acid and tricarboxylic acid intermediates cycle.Conclusions:The ~1H NMR metabolomic investigation combined with appropriate algorithms and pattern recognition procedures,gave an evidence for the existence of distinct metabolic differentiation of individuals,according to their gender,modulates with the infection risk. | Nurul Shahfiza Hasnah Osman Tang T.Hock Khozirah Shaari Abdel-Hamid Z Abdel-Hamid | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，6： | 0 |
| 7 | Synthesis and Characterization of New 3-(3-Hydroxyphenyl)-4- alkyl-3,4-dihydrobenzo[e][1,3]oxazepine-1,5-dione Compounds显示文摘有 n 在是从 2 ~ 18 的甚至同等值数字的一般公式 CnH2n+1CNO (公司) 2C6H4 (C6H4OH ) 的一系列 3-(3-hydroxyphenyl )-4-alkyl-3,4-dihydrobenzo[e][1,3]oxazepine-1,5-dione 混合物。这些混合物上的结构决心被显示纳入 oxazepine 戒指的终端烷基链充分被扩大的英尺红外光谱学执行。在在周围的温度的 DMSO 的 Conformational 分析经由高分辨率 1H NMR 和 13C NMR 光谱学第一次被执行。 | Osman, Hasnah Mohammad, AbdulKarim-Talaq Yeap, Guan-Yeow Adam, Farook | 2011 | Chinese Journal of Chemistry2011，29，7： | 0 |
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