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| 1 | Probe based confocal laser endomicroscopy of the pancreatobiliary system显示文摘AIM:To review applications of confocal laser endomicroscopy(CLE) in pancreatobiliary lesions and studies that assessed training and interpretation of images. METHODS: A computerized literature search was performed using OVID MEDLINE, EMBASE, Cochrane library, and the ISI Web of Knowledge from 1980 to October 2014. We also searched abstracts from major meetings that included the Digestive Disease Week, Canadian Digestive Disease Week and the United European Gastroenterology Week using a combination of controlled vocabulary and text words related to p CLE, confocal, endomicroscopy, probe-based confocal laser endomicroscopy, and bile duct to identify reports of trials. In addition, recursive searches and crossreferencing was performed, and manual searches of articles identified after the initial search was also completed. We included fully published articles and those in abstract form. Given the relatively recent introduction of CLE we included randomized trials and cohort studies.R E S U LT S : In the evaluation of indeterminate pancreatobiliary strictures CLE with ERCP compared to ERCP alone can increase the detection of cancerous strictures with a sensitivity of(98% vs 45%) andhas a negative predictive value(97% vs 69%), but decreased the specificity(67% vs 100%) and the positive predictive value(71% vs 100%) when compared to index pathology. Modifications in the classification systems in indeterminate biliary strictures have increased the specificity of p CLE from 67% to 73%. In pancreatic cystic lesions there is a need to develop similar systems to interpret and characterize lesions based on CLE images obtained. The presence of superficial vascular network predicts serous cystadenomas accurately. Also training in acquiring and interpretation of images is feasible in those without any prior knowledge in CLE in a relatively simple manner and computer-aided diagnosis software is a promising innovation. CONCLUSION: The role of p CLE in the evaluation of pancreatobiliary disorders might be better suited for those with an intermediate and low probability. | Majid A Almadi Helmut Neumann | 2015 | World Journal of Gastroenterology2015，21，44： | 6 |
| 2 | 成人原发结肠嗜酸性粒细胞增多症及嗜酸性结肠炎显示文摘目前,正常成人结肠黏膜中嗜酸性粒细胞数量以及嗜酸性结肠炎的组织学诊断标准尚未明确。本文为明确正常成人结肠黏膜中嗜酸性粒细胞数量,构建了原发结肠嗜酸性粒细胞增多症及嗜酸性结肠炎的临床病理诊断框架,对159名健康成人的左半结肠、横结肠以及右半结肠黏膜的嗜酸性粒细胞进行计数,并从120万例结肠活检病例的资料库里,提取诊断为结肠嗜酸性粒细胞增多症的成年患者资料,除复习所有病理切片外,并获取相关人口统计学信息、临床病理资料以及患者其它器官嗜酸性粒细胞增多症的信息。 | Turner K O Sinkre R A Neumann W L 尤晓萍 余英豪 | 2017 | 临床与实验病理学杂志2017，33，1： | 3 |
| 3 | 术前检测患者血液中总蛋白、白蛋白与白细胞介素-1受体拮抗剂作为切口疝修补术后是否出现血清肿的预测指标显示文摘患者切口疝修补术后出现血清肿是非常常见的,约占20%~30%,其中10%的患者渗液量超过50ml。出现血清肿并不一定出现并发症,但血清肿患者术后容易出现疼痛不适,尤其是补片感染导致修补手术失败,切口疝复发。对某些患者及时使用细针抽液,甚至是手术治疗都是必要的。 | Klink CD Binnebosel M Lucas AH Schachtrupp A Grommes J Conze J Klinge U Neumann U Junge K 宗振(译) 陈双(校) | 2012 | 中华疝和腹壁外科杂志(电子版)2012，6，2： | 2 |
| 4 | Vessel size and long-term outcome after coronary stent placement显示文摘 | Eleizi S Kastrati A Neumann F | 1998 | Circulation1998，98，18： | 1 |
| 5 | Recessively In herited Multiple Epiphyseal Dysplasia with Normal Stature,Club Foot and Double Layered Patella Caused by a DTDSTMutation显示文摘 | Superti Furga A Neumann I Riebel T | 1999 | J Med Genet1999，36，： | 1 |
| 6 | Musculoskeletal manifestations and autoantibody profile in 90 hepatits C virus infected Isreli patients显示文摘 | Buskila D Shnaider A Neumann L | 1998 | Semin Arthritis Rheum1998，28，2： | 1 |
| 7 | Quality of life in patients with paroxysmal atrial fibrillation after catheter ablation: results of long--term follow-up 显示文摘 | Erdogan A Carlsson J Neumann T | 2003 | Pacing Clin Electrophysiol2003，26，3： | 1 |
| 8 | Annual cycles of water vapour and carbon dioxide fluxes in and above a boreal aspen forest显示文摘 | BLACK T A HARTOG G D NEUMANN H H | 1996 | Global Change Biology1996，2，： | 1 |
| 9 | DNA damage induces alternative lengthening of telomeres (ALT) -asso-ciated promyelocytic Leukemia bodies that preferentially associate with linear telomeric DNA显示文摘 | Fasching CL Neumann AA Muntoni A | 2007 | Cancer Res2007，67，15： | 1 |
| 10 | Experimental bronchial asthma-the strength of the species rat 显示文摘 | Tschernig T Neumann D Pich A | 2008 | Curr Drug Targets2008，9，6： | 1 |
| 11 | Significance of a T - lymphoeytotoxie erossmatch in liver and combined liver - kidney transplantation 显示文摘 | Neumann UP Lang M Moldenhaner A | 2001 | Transplantation2001，71，8： | 1 |
| 12 | Evaluation of prolonged antithrombotic pretreatment ( 'cooling-off' strategy) before intervention in patients with unstable coronary syndromes: a randomized controlled trial 显示文摘 | Neumann FJ Kastrati A Pogatsa-Murray G | 2003 | JAMA2003，290，： | 1 |
| 13 | Activity of enzymes immobilized in colloidal spherical polyelectrolyte brushes 显示文摘 | Haupt B Neumann T Wittemann A | 2005 | Biomacromolecules2005，6，： | 1 |
| 14 | Effect of increasing breast milk docosahexaenoic acid on plasma and erythrocyte phospholipid fatty ac- ids and neural indices of exclusively breast fed infants显示文摘 | GIBSON R A NEUMANN M A | 1997 | European Journal of Clinical Nutrition1997，51，9： | 1 |
| 15 | Structural and functional properties of ribosomal protein L7 fromhumans and rodents显示文摘 | HEMMERICH P VON MIKECZ A NEUMANN F | 1993 | Nucleic Acids Res1993，21，2： | 1 |
| 16 | Long term failure of engdoscopic gastroplication(Endocinch)显示文摘 | Schiefke I Zabel-Langhennig A Neumann S Feisthammel J Moessner J Caca K | 2005 | Gut2005，54，： | 1 |
| 17 | Anthropogenic influences on groundwater arsenic concentrations in Bangladesh 显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B M | 2010 | Nature Geoscience2010，3，1： | 1 |
| 18 | Investigation of Reproducibility of Third-Level Characteristics显示文摘 | Anthonioz A Egli N Champod C Neumann C Puch-Soils R Bromage-Griffiths A | | 0，，02： | 1 |
| 19 | Abeiximab and heparin versus bivalirudin for non-ST-elevation myocardial in-farction 显示文摘 | Kastrati A Neumann F J Schulz S | 2011 | N Engl J Med2011，365，21： | 1 |
| 20 | Adv Colloid Intelface Sci显示文摘 | Kwok D Y Neumann A W | 1999 | 81(3) :1671999，81，3： | 1 |
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