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| 1 | Achalasia: A review of clinical diagnosis, epidemiology,treatment and outcomes显示文摘Achalasia is a neurodegenerative motility disorder of the oesophagus resulting in deranged oesophageal peristalsis and loss of lower oesophageal sphincter function.Historically,annual achalasia incidence rates were believed to be low,approximately 0.5-1.2 per 100000.More recent reports suggest that annual incidence rates have risen to 1.6 per 100000 in some populations.The aetiology of achalasia is still unclear but is likely to be multi-factorial.Suggested causes include environmental or viral exposures resulting in inflammation of the oesophageal myenteric plexus,which elicits an autoimmune response.Risk of achalasia may be elevated in a sub-group of genetically susceptible people.Improvement in the diagnosis of achalasia,through the introduction of high resolution manometry with pressure topography plotting,has resulted in the development of a novel classification system for achalasia.This classification system can evaluate patient prognosis and predict responsiveness to treatment.There is currently much debate over whether pneumatic dilatation is a superior method compared to the Heller’s myotomy procedure in the treatment of achalasia.A recent com-parative study found equal efficacy,suggesting that patient preference and local expertise should guide the choice.Although achalasia is a relatively rare condition,it carries a risk of complications,including aspiration pneumonia and oesophageal cancer.The risk of both squamous cell carcinoma and adenocarcinoma of the oesophagus is believed to be significantly increased in patients with achalasia,however the absolute excess risk is small.Therefore,it is currently unknown whether a surveillance programme in achalasia patients would be effective or cost-effective. | Orla M O'Neill Brian T Johnston Helen G Coleman | 2013 | World Journal of Gastroenterology2013，19，35： | 26 |
| 2 | Comparison of dopamine receptor antagonists on hyperlocomotion induced by cocaine, amphetamine, MK-801 and the dopamine D1 agonist C-APB in mice显示文摘 | O'Neill MF Shaw G | 1999 | Psyehopharmacology (Berl)1999，145，3： | 1 |
| 3 | Melatonin for cashmere production in breeding does 显示文摘 | O'NEILL K LITHERLAND A J HAMILTON G | 1992 | Journal of Pineal Research1992，52，： | 1 |
| 4 | Dropwise condensation of steam on electroplated silver surfaces 显示文摘 | O'Neill G A Westwater J W | 1984 | International Journal of Heat and Mass Transfer1984，27，9： | 1 |
| 5 | Reducing methane emissions in sheep by immunization against rumen methanogens显示文摘 | Wright A D G Kennedy P O Neill C J | 2004 | Vaccine2004，22，： | 1 |
| 6 | Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomograph显示文摘 | RAFF G L GALLAGHER M J NEILL W W | 2005 | J Am Coll Cardiol2005，46，： | 1 |
| 7 | Measurements of aerobic metabolism of a school of horse mackerel at different swimming speeds显示文摘 | Soofiani N M and O'Neill F G | 1996 | Journal of Fish Biology1996，49，5： | 1 |
| 8 | Multifrequency Microwave Radiometer Measurements of Soil Moisture显示文摘 | Njoku E G O'Neill P E | 1982 | IEEE Trans Geo sci Remote Sensing1982，220，4： | 1 |
| 9 | FOXM1 is adownstream target of Glil in basal cell carcinomas 显示文摘 | Teh M T Wong S T Neill G W | 2002 | Cancer Res2002，62，16： | 1 |
| 10 | Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria 显示文摘 | BIAGINI G A VIRIYAVEJAKUL O O’NEILL P M | 2006 | Antimicrob Agents Chemother2006，50，： | 1 |
| 11 | Using soil 13C to detect the historic presence of schizachyrium scoparium (little bluestem) grasslands on Martha's vineyard显示文摘 | Peterson G G Neill C | 2003 | Restoration Ecology2003，11，1： | 1 |
| 12 | 16S rRNA phylogenetic analysis of the bacterial endosymbionts associated with cytoplasmic incompatibility in insects显示文摘 | Scott L O'Neill Rosanna G | 1992 | Proceeding National Academic Science USA1992，89，： | 1 |
| 13 | The family of five: TIR-domain-eontaining adaptors in Toll-like receptor signalling 显示文摘 | O' Neill L A Bowie A G | 2007 | Nat Rev Immunol2007，7，： | 1 |
| 14 | The effects of intracortical endothelin-1 injections on skilled forelimb use:implications for modelling recovery of function after stroke显示文摘 | Gilmour G Iversen SD O'Neill MF | | 0，，02： | 1 |
| 15 | The Value of the World's Ecosystem Services and Natural Capital显示文摘 | Costanza R d'Arge R de Groot R Farberk S Grasso M Hannon B Limburg K Naeem S O'Neill R V Paruelo J Raskin R G Suttonkk P van den Belt M | | 0，，6630： | 1 |
| 16 | Randomized trial comparing holmium laser enucleation of prostate with plasmakinetic enucleation of prostate for treatment of benign prostatic hyperplasia 显示文摘 | NEILL M G GILLING P J KENNETT K M | 2006 | Urology2006，68，5： | 1 |
| 17 | Endovascular treatment of traumatic dural sinus thrombosis:case report显示文摘 | Kuether T O'Neill Nesbit G M | 1998 | Neurosurgery1998，42，5： | 1 |
| 18 | 5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine,cocaine,and MK-801 but not D1 agonist C-APB显示文摘 | O'Neill MF Heron-Maxwell CL Shaw G | 1999 | Pharmacol Biochem Behav1999，63，： | 1 |
| 19 | Comprehensive geriatric assessment for older adults admitted to hospital显示文摘 | Ellis G Whitehead MA O'Neill D | 2011 | Cochrane Database Syst Rev2011，，00： | 1 |
| 20 | Public engagement with carbon and climate change:to what extent is the public'carbon capable'?显示文摘 | Whitmarsh L Seyfang G&O'Neill S | 2011 | Global Environmental Change2011，，21： | 1 |
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