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| 1 | Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease显示文摘Inflammatory bowel diseases(IBDs) are chronic disorders of modern society, requiring management strategies aimed at prolonging an active life and establishing the exact etiology and pathogenesis.These idiopathic diseases have environmental, genetic,immunologic, inflammatory, and oxidative stress components. On the one hand, recent advances have shown that abnormal immune reactions against the microorganisms of the intestinal flora are responsible for the inflammation in genetically susceptible individuals. On the other hand, in addition to T helper cell-type(Th) 1 and Th2 immune responses,other subsets of T cells, namely regulatory T cells and Th17 maintained by IL-23 are likely to develop IBD. IL-23 acts on innate immune system members and also facilitates the expansion and maintenance of Th17 cells. The IL-17/IL-23 axis is relevant in IBD pathogenesis both in human and experimental studies. Novel biomarkers of IBD could be calprotectin,microRNAs, and serum proinflammatory cytokines.An efficient strategy for IBD therapy is represented by the combination of IL-17 A and IL-17 F in acute IL-17 A knockout TNBS-induced colitis, and also definite decrease of the inflammatory process in IL-17 F knockout, DSS-induced colitis have been observed.Studying the correlation between innate and adaptive immune systems, we hope to obtain a focused reviewin order to facilitate future approaches aimed at elucidating the immunological mechanisms that control gut inflammation. | Cristina-Sorina Cǎanǎ Ioana Berindan Neagoe Vasile Cozma Cristian Magdas Flaviu Tǎbǎan Dan Lucian Dumitrasu | 2015 | World Journal of Gastroenterology2015，21，19： | 37 |
| 2 | Effect of everolimus on the immunomodulation of the human neutrophil inflammatory response and activation显示文摘 | Damien Vitiello | 2015 | Cellular & Molecular Immunology2015，12，1： | 4 |
| 3 | Association of Prothrombin (A20210G) and Factor V Leiden (AS06G)with Recurrent Pregnancy Loss显示文摘 | Mieria D Szmal C Neagos D | 2012 | Maedica2012，7，3： | 1 |
| 4 | Risk factors for colorectal cancer: an epidemiologic descriptive study of a series of 333 patients显示文摘 | Neagoe A Molnar AM Acalovschi M | 2004 | Rom J Gastroenterol2004，13，3： | 1 |
| 5 | Risk factors for colorectal cancer:an epidemiologic descriptive study of a series of 333patients显示文摘 | Neagoe A Molnar AM Acalovschi M | 2004 | Rom J Gastroenterol2004，13，3： | 1 |
| 6 | CLC chloride channels and transporters显示文摘 | Jentsch T J Neagoe I Scheel O | 2005 | Curr OpinNeurobiol2005，15，： | 1 |
| 7 | Vascular endothelial growth factor(VEGF)-A165-induced prostacyclin synthesis requires the activation of VEGF receptor-1 and-2 heterodimer 显示文摘 | Neagoe PF Lemieux C Sirois MG | 2005 | Biol Chem2005，280，11： | 1 |
| 8 | Investigatorblind,placebo-controlled,randomized comparative study on combined vacuum and intense pulsed light versus intense pulsed light devices in both comedonal and papulopustular acne显示文摘 | Ianosi S Neagoe D Calbureanu M | 2013 | J Cosmet Laser Ther2013，15，5： | 1 |
| 9 | Expression and release of angiopoietin-1 from human neutrophils:intracellular mechanisms显示文摘 | Neagoe P E Brkovic Hajjar F | 2009 | Growth Factors2009，27，6： | 1 |
| 10 | Titin isoform switch in ischemic human heart disease显示文摘 | Neagoe C Kulke M del Monte F | 2002 | Circulation2002，106，： | 1 |
| 11 | The importance of screening and prenatal diagnosis in the identification of the numerical chromosomal abnormalities 显示文摘 | Neagos D Cretu R Sfetea RC | 2011 | Maedica (Buchar)2011，6，3： | 1 |
| 12 | Effects of zearalenone and its derivatives on porcine immune response显示文摘 | Daniela E. Marin Ionelia Taranu Radu Burlacu Gina Manda Monica Motiu Ionela Neagoe Catalin Dragomir Mariana Stancu Loredana Calin | 2011 | Toxicology in Vitro2011，，8： | 1 |
| 13 | Investigator-blind, placebocontrolled, randomized comparative study on combined vacuum andintense pulsed light versus intense pulsed light devices in both comedonal and papulopustularacne 显示文摘 | Ianosi S Neagoe D Calbureanu M | 2013 | J Cosmet Laser Ther2013，15，5： | 1 |
| 14 | The importance of screening and prenatal diagnosis in the identification of the numerical chromosomal abnormalities 显示文摘 | Neagos D Cretu R Sfetea RC | 2011 | Maedica ( Bu- char)2011，6，3： | 1 |
| 15 | Identification of VEGF re- ceptor- 2 tyrosine phosphorylation sites involved in VEGF- mediated endothelial platelet -activating factor synthesis 显示文摘 | Rechka A Neagoe PE Gratton JP | 2010 | Canadian Journal of Physiology and Pharmacology2010，88，10： | 1 |
| 16 | Alcohol affects the skeletal muscle proteins,titin and nebulin in male and female rats显示文摘 | Hunter RJ Neagoe C Jarvelainen HA | 2003 | J Nutr2003，133，4： | 1 |
| 17 | The Utility of the Predictive Scores in Polytrauma with Abdomino-pelvic Injuries: A Series of 38 Patients显示文摘 | T~rfik A Bancu S Neagoe R | 2013 | Chirurgia (Bucharest Romania: 1990)2013，109，1： | 1 |
| 18 | The importance of screening and prenatal diagnosis in the identification of the numerical chromosomal abnormalities显示文摘 | Neagos D Cretu R Sfetea RC | | 0，，： | 1 |
| 19 | 显示文摘 | Neagoe C Kulke M del Monte F | 2002 | Circulation2002，106，： | 1 |
| 20 | Effects of zearalenone on oxidative stress and inflam-mation in weanling piglets 显示文摘 | MARIN D E PISTOL G C NEAGOE L V | 2013 | Food and ChemicalToxicology2013，58，： | 1 |
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