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| 1 | Optical metasurfaces: new generation building blocks for multi-functional optics显示文摘Optical metasurfaces(OMs)have emerged as promising candidates to solve the bottleneck of bulky optical elements.OMs offer a fundamentally new method of light manipulation based on scattering from resonant nanostructures rather than conventional refraction and propagation,thus offering efficient phase,polarization,and emission control.This perspective highlights state of the art OMs and provides a roadmap for future applications,including active generation,manipulation and detection of light for quantum technologies,holography and sensing. | Dragomir Neshev Igor Aharonovich | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 2 | Infrared upconversion imaging in nonlinear metasurfaces显示文摘Infrared imaging is a crucial technique in a multitude of applications,including night vision,autonomous vehicle navigation,optical tomography,and food quality control.Conventional infrared imaging technologies,however,require the use of materials such as narrow bandgap semiconductors,which are sensitive to thermal noise and often require cryogenic cooling.We demonstrate a compact all-optical alternative to perform infrared imaging in a metasurface composed of GaAs semiconductor nanoantennas,using a nonlinear wave-mixing process.We experimentally show the upconversion of short-wave infrared wavelengths via the coherent parametric process of sum-frequency generation.In this process,an infrared image of a target is mixed inside the metasurface with a strong pump beam,translating the image from the infrared to the visible in a nanoscale ultrathin imaging device.Our results open up new opportunities for the development of compact infrared imaging devices with applications in infrared vision and life sciences. | Rocio Camacho-Morales Davide Rocco Lei Xu Valerio Flavio Gili Nikolay Dimitrov Lyubomir Stoyanov Zhonghua Ma Andrei Komar Mykhaylo Lysevych Fouad Karouta Alexander Dreischuh Hark Hoe Tan Giuseppe Leo Costantino De Angelis Chennupati Jagadish Andrey E.Miroshnichenko Mohsen Rahmani Dragomir N.Neshev | 2021 | Advanced Photonics2021，3，3： | 11 |
| 3 | Enhanced light-matter interactions in dielectric nanostructures via machine-learning approach显示文摘A key concept underlying the specific functionalities of metasurfaces is the use of constituent components to shape the wavefront of the light on demand.Metasurfaces are versatile,novel platforms for manipulating the scattering,color,phase,or intensity of light.Currently,one of the typical approaches for designing a metasurface is to optimize one or two variables among a vast number of fixed parameters,such as various materials’properties and coupling effects,as well as the geometrical parameters.Ideally,this would require multidimensional space optimization through direct numerical simulations.Recently,an alternative,popular approach allows for reducing the computational cost significantly based on a deep-learning-assisted method.We utilize a deep-learning approach for obtaining high-quality factor(high-Q)resonances with desired characteristics,such as linewidth,amplitude,and spectral position.We exploit such high-Q resonances for enhancedlight–matter interaction in nonlinearoptical metasurfaces and optomechanical vibrations,simultaneously.We demonstrate that optimized metasurfaces achieve up to 400-fold enhancement of the third-harmonic generation;at the same time,they also contribute to 100-fold enhancement of the amplitude of optomechanical vibrations.This approach can be further used to realize structures with unconventional scattering responses. | Lei Xu Mohsen Rahmani Yixuan Ma Daria ASmirnova Khosro Zangeneh Kamali Fu Deng Yan Kei Chiang Lujun Huang Haoyang Zhang Stephen Gould Dragomir N.Neshev Andrey E.Miroshnichenko | 2020 | Advanced Photonics2020，2，2： | 8 |
| 4 | Enhanced second-harmonic generation from two-dimensional MoSe_(2) on a silicon waveguide显示文摘Two-dimensional transition-metal dichalcogenides(TMDCs)with intrinsically broken crystal inversion symmetry and large secondorder nonlinear responses have shown great promise for future nonlinear light sources.However,the sub-nanometer monolayer thickness of such materials limits the length of their nonlinear interaction with light.Here,we experimentally demonstrate the enhancement of the second-harmonic generation from monolayer MoSe_(2) by its integration onto a 220-nm-thick silicon waveguide.Such on-chip integration allows for a marked increase in the interaction length between the MoSe_(2) and the waveguide mode,further enabling phase matching of the nonlinear process.The demonstrated TMDC–silicon photonic hybrid integration opens the door to second-order nonlinear effects within the silicon photonic platform,including efficient frequency conversion,parametric amplification and the generation of entangled photon pairs. | Haitao Chen Vincent Corboliou Alexander S Solntsev Duk-Yong Choi Maria A Vincenti Domenico de Ceglia Costantino de Angelis Yuerui Lu Dragomir N Neshev | 2017 | Light(Science & Applications)2017，6，1： | 7 |
| 5 | Boosting third-harmonic generation by a mirror-enhanced anapole resonator显示文摘We demonstrate that a dielectric anapole resonator on a metallic mirror can enhance the third harmonic emission by two orders of magnitude compared to a typical anapole resonator on an insulator substrate.By employing a gold mirror under a silicon nanodisk,we introduce a novel characteristic of the anapole mode through the spatial overlap of resonantly excited Cartesian electric and toroidal dipole modes.This is a remarkable improvement on the early demonstrations of the anapole mode in which the electric and toroidal modes interfere off-resonantly.Therefore,our system produces a significant near-field enhancement,facilitating the nonlinear process.Moreover,the mirror surface boosts the nonlinear emission via the free-charge oscillations within the interface,equivalent to producing a mirror image of the nonlinear source and the pump beneath the interface.We found that these improvements result in an extremely high experimentally obtained efficiency of 0.01%. | Lei Xu Mohsen Rahmani Khosro Zangeneh Kamali Aristeidis Lamprianidis Lavinia Ghirardini Jürgen Sautter Rocio Camacho-Morales Haitao Chen Matthew Parry Isabelle Staude Guoquan Zhang Dragomir Neshev Andrey E.Miroshnichenko | 2018 | Light(Science & Applications)2018，7，1： | 5 |
| 6 | Multidimensional synthetic chiral-tube lattices via nonlinear frequency conversion显示文摘Geometrical dimensionality plays a fundamentally important role in the topological effects arising in discrete lattices.Although direct experiments are limited by three spatial dimensions,the research topic of synthetic dimensions implemented by the frequency degree of freedom in photonics is rapidly advancing.The manipulation of light in these artificial lattices is typically realized through electro-optic modulation;yet,their operating bandwidth imposes practical constraints on the range of interactions between different frequency components.Here we propose and experimentally realize all-optical synthetic dimensions involving specially tailored simultaneous short-and long-range interactions between discrete spectral lines mediated by frequency conversion in a nonlinear waveguide.We realize triangular chiral-tube lattices in three-dimensional space and explore their four-dimensional generalization.We implement a synthetic gauge field with nonzero magnetic flux and observe the associated multidimensional dynamics of frequency combs,all within one physical spatial port.We anticipate that our method will provide a new means for the fundamental study of high-dimensional physics and act as an important step towards using topological effects in optical devices operating in the time and frequency domains. | Kai Wang Bryn A.Bell Alexander S.Solntsev Dragomir N.Neshev Benjamin J.Eggleton Andrey A.Sukhorukov | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 7 | Nonlinear frequency conversion in optical nanoantennas and metasurfaces:materials evolution and fabrication显示文摘Nonlinear frequency conversion is one of the most fundamental processes in nonlinear optics.It has a wide range of applications in our daily lives,including novel light sources,sensing,and information processing.It is usually assumed that nonlinear frequency conversion requires large crystals that gradually accumulate a strong effect.However,the large size of nonlinear crystals is not compatible with the miniaturisation of modern photonic and optoelectronic systems.Therefore,shrinking the nonlinear structures down to the nanoscale,while keeping favourable conversion efficiencies,is of great importance for future photonics applications.In the last decade,researchers have studied the strategies for enhancing the nonlinear efficiencies at the nanoscale,e.g.by employing different nonlinear materials,resonant couplings and hybridization techniques.In this paper,we provide a compact review of the nanomaterials-based efforts,ranging from metal to dielectric and semiconductor nanostructures,including their relevant nanofabrication techniques. | Mohsen Rahmani Giuseppe Leo Igal Brener Anatoly V. Zayats Stefan A. Maier Costantino De Angelis Hoe Tan Valerio Flavio Gili Fouad Karouta Rupert Oulton Kaushal Vora Mykhaylo Lysevych Isabelle Staude Lei Xu Andrey E. Miroshnichenko Chennupati Jagadish Dragomir N. Neshev | 2018 | Opto-Electronic Advances2018，1，10： | 3 |
| 8 | Influence of Cr, Mn and Mo Addition on Structure and Properties of V Microalloyed Medium Carbon Steels显示文摘The effect of austenitizing temperature and Cr, Mo and Mn addition on microstructure and mechanical properties of V microalloyed medium carbon steel has been studied by means of metallography and mechanical testing. The addition of Cr, Mn and Mo leads to a decrease in yield strength (YS) by approximate 100 MPa in comparison to the base steel. It is assumed that Mn and Mo increase hardenability by promoting the formation of bainitic sheaves (BS), i.e. by suppressing the formation of ferrite-pearlite and acicular ferrite (FP-AF). Cr at the level used in this work is not that effective. Presence and packet size of bainitic sheaves decrease the Charpy V-notch impact energy at 20℃ (CVN20) in comparison to ferrite-pearlite and acicular ferrite microstructures. | Abdunnaser Fadel Dragomir Glii Nenad Radovi Djordje Drobnjak | 2012 | Journal of Materials Science & Technology2012，28，11： | 2 |
| 9 | Key questions about the checkpoint blockade-are microRNAs an answer?显示文摘The introduction of immune-checkpoint blockade in the cancer therapy led to a paradigm change of the management of late stage cancers. There are already multiple FDA approved checkpoint inhibitors and many other agents are undergoing phase 2 and early phase 3 clinical trials. The therapeutic indication of immune checkpoint inhibitors expanded in the last years, but still remains unclear who can benefit. Micro RNAs are small RNAs with no coding potential. By complementary pairing to the 3' untranslated region of messenger RNA, microRNAs exert posttranscriptional control of protein expression. A network of microRNAs directly and indirectly controls the expression of checkpoint receptors and several microRNAs can target multiple checkpoint molecules,mimicking the therapeutic effect of a combined immune checkpoint blockade. In this review, we will describe the microRNAs that control the expression of immune checkpoints and we will present four specific issues of the immune checkpoint therapy in cancer:(1) imprecise therapeutic indication,(2) difficult response evaluation,(3) numerous immunologic adverse-events, and(4)the absence of response to immune therapy. Finally, we propose microRNAs as possible solutions for these pitfalls. We consider that in the near future microRNAs could become important therapeutic partners of the immune checkpoint therapy. | Mihnea Dragomir Baoqing Chen Xiao Fu George A.Calin | 2018 | Cancer Biology & Medicine2018，15，2： | 2 |
| 10 | Enhanced generation of nondegenerate photon pairs in nonlinear metasurfaces显示文摘We predict theoretically a regime of photon-pair generation driven by the interplay of multiple bound states in the continuum resonances in nonlinear metasurfaces.This nondegenerate photon-pair generation is derived from the hyperbolic topology of the transverse phase matching and can enable orders-of-magnitude enhancement of the photon rate and spectral brightness,as compared to the degenerate regime.We show through comprehensive simulations that the entanglement of the photon pairs can be tuned by varying the pump polarization,which can underpin future advances and applications of ultracompact quantum light sources. | Matthew Parry Andrea Mazzanti Alexander Poddubny Giuseppe Della Valle Dragomir N.Neshev Andrey A.Sukhorukov | 2021 | Advanced Photonics2021，3，5： | 2 |
| 11 | Effect of depletion of monocytes/macrophages on early aortic valve lesion in experimental hyperlipidemia显示文摘 | Calin MV Manduteanu I Dragomir E | 2009 | Cell Tissue Res2009，336，： | 1 |
| 12 | On Hadamard''''s inequality for convex functions on the co-ordinates in a rectangle from the plane显示文摘 | Dragomir S S | | 0，，04： | 1 |
| 13 | Resistin up-regulates fractalkine expression in human endothelial cells:lack of additive effect with TNF-alpha显示文摘 | Manduteanu I Dragomir E Calin M | 2009 | Biochem Biophys Res Commun2009，381，1： | 1 |
| 14 | Two mappings in connection to Hadamard' s inequalities显示文摘 | Dragomir S S | 1992 | J Math Anal Appl1992，，： | 1 |
| 15 | Two mappings in connection to Hadamard's inequality 显示文摘 | S S dragomir | 1992 | Math Anal Appl1992，，167： | 1 |
| 16 | A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children 显示文摘 | Hurduc V Plesca D Dragomir D | 2009 | Acta Paediatr2009，98，1： | 1 |
| 17 | Role of galectin 3 in classical and alternative macrophage activation in the liver following acetaminophen intoxication 显示文摘 | Dragomir AC Sun R Choi H | 2012 | J Immunol2012，189，12： | 1 |
| 18 | Inequalities of Hadamard'S type for Lipsch-Tzian Mappings and Their Applications显示文摘 | Dragomir S S Cho Y J Kim S S | 2000 | Journal of Mathematical Analysis and Applications2000，245，： | 1 |
| 19 | On Hadamard' s inequality for convex func- tions 显示文摘 | S S Dragomir | 1992 | Mat Balkanica1992，，6： | 1 |
| 20 | Factors associated with prolonged hospitalization,readmission,and death in elderly heart failure patients in western Romania显示文摘 | Gyalai-Korpos I Ancusa O Dragomir T | 2015 | Clin Interv Aging2015，11，10： | 1 |
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