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| 1 | Lipopolysaccharide Enhances the Production of Nicotine-Induced Prostaglandin E2 by an Increase in Cyclooxygenase-2 Expression in Osteoblasts显示文摘以前的研究显示了那脂肪的多糖(LPS ) 在匾的 fromGram 否定的细菌导致前列腺素 E_2 (PGE_2 ) 的版本,它在吸烟的 periodontitis,和那棵烟草支持牙槽的骨头再吞可能是为 periodontitis 的发展和严厉的一个重要风险因素。我们在碱性磷酸酶(ALPase ) 上决定了烟碱 andLPS 的效果活动, PGE_2 生产,和表示 ofcyclooxygenase (COX-1, COX-2 ) , PGE_2 受体 Ep1-4,和在人的 osteoblastic Saos-2 房间的巨噬细胞殖民地刺激因素(M-CSF ) 。房间与 10 ~ 是有教养的(-3) M 烟碱面对 0, 1,或 10 μ g /ml LPS,或与 LPS 独自一个。ALPase 活动独自在与烟碱或 LPS 有教养的房间减少了,并且在与烟碱和 LPS 有教养的那些进一步减少了,而 PGE_2 生产显著地在前者增加了并且在后者进一步增加了。由自己,烟碱没影响 COX-1, COX-2,任何 PGE_2 受体,或 M-CSF 的表示,但是烟碱和 LPS 什么时候是现在, COX-2 的表示, Ep3, Ep4,和 M-CSF,显著地增加。10 ~ 的同时的增加(-4) M 消炎痛在 ALPase 活动, PGE_2 生产,和 M-CSF 表示消除了烟碱和 LPS 的效果。proteinkinase A 的 Phosphorylation 在与烟碱和 LPS 有教养的房间高。这些结果建议 LPS 由造骨细胞的 COX-2 表示的增加提高导致烟碱的 PGE_2 的生产, thatnicotine-LPS-induced PGE_2 首先在 autocrine orparacnne 模式与造骨细胞 Ep4 受体交往,并且 nicotine-LPS-induced PGE_2 然后减少 ALPase 活动和 increasesM-CSF 表示。 | Maiko SHOJI Natsuko TANABE Narihiro MITSUI Naoto SUZUKI Osamu TAKEICHI Tomoko KATONO Akira MOROZUMI Masao MAENO | 2007 | Acta Biochimica et Biophysica Sinica2007，39，3： | 9 |
| 2 | Gastric xanthoma is a predictive marker for metachronous and synchronous gastric cancer显示文摘AIM To investigate predictive markers for metachronous and synchronous gastric cancer(GC), which can develop after endoscopic submucosal dissection(ESD).METHODS A total of 352 patients underwent ESD for early GC at NTT West Osaka Hospital between June 2006 and February 2016. Exclusion criteria were as follows: Remnant stomach, unknown Helicobacter pylori status, and endoscopic observation of the whole stomach outside our hospital. We analyzed data from 192 patients comprising 109 patients with solitary GC(Group A) and 83 with metachronous and synchronous GC(Group B). We retrospectively investigated the clinicopathological and endoscopic characteristics, and endoscopic risk score as predictive markers for GC.RESULTS The median age of Group B [72 years(interquartile range 63-78)] was significantly higher than that of Group A [66 years(interquartile range 61-74), respectively, P = 0.0009]. The prevalence of intestinal metaplasia in Group B tended to be higher than that in Group A(57.8% vs 45.0%, P = 0.08). The prevalence of gastric xanthoma(GX) in Group B was significantly higher than that in Group A(54.2% vs 32.1%, P = 0.003). The atrophy score in Group B was significantly higher than that in Group A(P = 0.005). Multivariate analysis revealed that higher age and the presence of GX were independently related to metachronous and synchronous GC [OR = 1.04(1.01-1.08), P = 0.02; and OR = 2.11(1.14-3.99), P = 0.02, respectively].CONCLUSION The presence of GX is a useful predictive marker for metachronous and synchronous GC. | Narihiro Shibukawa Shohei Ouchi Shuji Wakamatsu Yuhei Wakahara Akira Kaneko | 2017 | World Journal of Gastrointestinal Oncology2017，9，8： | 8 |
| 3 | Synthesis of polythionphene derivatives bearing ferroelectric liquid crystalline substituents 显示文摘 | Goto Hiromasa Dai Xiaoman Narihiro Harunori | 2004 | Macromolecules2004，37，37： | 1 |
| 4 | Highly Reliable Oxide-Semiconductor TFT for AM-OLED Display显示文摘 | Toshiaki Arai Narihiro Morosawa Kazuhiko Tokunaga | 2010 | SID Symposium Digest2010，，： | 1 |
| 5 | Thermal degradation and flame retardancy of Ethylene-vinyl alcohol copolymer blended with ammonium polyphosphate显示文摘 | Narihiro M Hiroaki S | | 0，，： | 1 |
| 6 | Diffraction efficiency analysis of a parallel-aligned nematic-liquid-crystal spatial light modulator显示文摘 | Naohisa Mukohzaka Narihiro Yoshida Haruyoshi Toyoda | 1994 | Applied Optics1994，33，14： | 1 |
| 7 | Microbial communities in anaerobic digestion processes for waste and wastewater treatment:a microbiological update显示文摘 | Narihiro T Sekiguchi Y | 2007 | Curt Opin Biotechnol2007，18，： | 1 |
| 8 | Seasonal microbial community dynamics in a flowerpot-using personal composting system for disposal of household biowaste显示文摘 | Hiraishi A Yamanaka Y Narihiro T | 2000 | The Journal General Applied Microbiology2000，46，3： | 1 |
| 9 | Synthesis of polythiophene derivatives bearing ferroelectric liquid crystalline substituents显示文摘 | GOTO H DAI XM NARIHIRO H | 2004 | Maemmoleeules2004，37，7： | 1 |
| 10 | Thermal degradation and flame retardancy of ethylene-vinyl alcohol copolymer blended with ammonium polyphosphate显示文摘 | Narihiro M Hiroaki S | 2003 | Polym Degrad Stab2003，79，： | 1 |
| 11 | Comparative A- nalysis of Bacterial and Archaeal Communities in Metha- nogenic Sludge Granules from Upflow Anaerobic Sludge Blanket Reactors Treating Various Food-Processing, High-Strength Organic Wastewaters 显示文摘 | Narihiro T Terada T Kikuchi K | 2009 | Microbes Envi- ron2009，24，2： | 1 |
| 12 | Microbial communities in anaerobic digestion processes for waste and wastewater treatment: a microbiological update显示文摘 | Takashi Narihiro Yuji Sekiguchi | 2007 | Current Opinion in Biotechnology2007，，3： | 1 |
| 13 | Molecular Cloning and Expression of a Novel Human Aquaporin from Adipose Tissue with Glycerol Permeability显示文摘 | Hiroshi Kuriyama Shoko Kawamoto Narihiro Ishida Ikko Ohno Shiro Mita Yuji Matsuzawa Kenichi Matsubara Kousaku Okubo | 1997 | Biochemical and Biophysical Research Communications1997，，1： | 1 |
| 14 | Activity and Phylo-genetic Composition of Proteolytic Bacteria in Mesophilie Fed - batch Garbage Composters显示文摘 | Takashi Narihiro Satoru Takebayashi Akira Hiraishi | 2004 | Microbes Environ2004，19，4： | 1 |
| 15 | Sub-50 nm physical gate length CMOS technology and beyond using steep halo显示文摘 | Wakabayashi H Ueki M Narihiro M | 2002 | IEEE Trans Electron Devices2002，49，1： | 1 |
| 16 | Thermal degradation and flame retardancy of ethylene-vinyl alcohol copolymer blended with ammonium polyphosphate显示文摘 | Narihiro Matsuda Hiroaki Shirasaka Keisuke Takayama Tomoyuki Ishikawa Kunihiko Takeda | 2002 | Polymer Degradation and Stability2002，，1： | 1 |
| 17 | Thermal degradation and flame retardancy of ethylene-vinyl alcohol copolymer blended with ammonium polyphosphate显示文摘 | Narihiro M Hiroaki S Keisuke T | 2003 | Polymer Degradation and Stability2003，79，1： | 1 |
| 18 | A new automatic exposure system for digital still cameras显示文摘 | Tetsuya Kuno Hiroaki Sugiura Narihiro Matoba | 1998 | IEEE Transactions on Consumer Electronics1998，44，1： | 1 |
| 19 | The nexus of syn- trophy-associated microbiota in anaerobic digestion revealed by long-term enrichment and community survey 显示文摘 | Narihiro T Nobu M K Kim N | 2015 | Envi- ronmental Microbiology2015，17，5： | 1 |
| 20 | Optimal compressive force induces bone formation via increasing bone morphogenetic proteins production and decreasing their antagonists production by Saos-2 cells显示文摘 | Narihiro Mitsui Naoto Suzuki Masao Maeno Momoko Yanagisawa Yuki Koyama Kichibee Otsuka Noriyoshi Shimizu | 2005 | Life Sciences2005，，23： | 1 |
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