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151篇 您的检索式:作者名="Najar"
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1Casein Kinase 2 Negatively Regulates Abscisic Acid-Activated SnRK2s in the Core Abscisic Acid-Signaling Module显示文摘SnRK2 kinases, PP2C 磷酸酶和 PYR/PYL/RCAR 受体组成表明被认为内在的性质包含所有到的模块的核心 abscisic 酸(骆驼毛的织物) 自我调整荷尔蒙信号产量。这里,我们识别酷蛋白 Kinase (CK ) 2 作为 SnRK2 的一个新奇否定管理者。CK2 phosphorylates 在 SnRK2 的 ABA 框的保存丝氨酸的簇,增加它的绑定到 PP2C 和被触发的蛋白质降级。因而, CK2 行动在到不能生活的刺激的 SnRK2 蛋白质层次,以及 kinase 活动和它的反应上有含意。Belmiro Vilela Elena Najar Victoria Lumbreras Jeffrey Leung Montserrat Pages 2015Molecular Plant2015,8,5:8
2Benign retroperitoneal schwannoma presenting as colitis:A case report显示文摘We report a case of a patient presenting with clinical,radiological and endoscopic features of colitis due to a compressive left para-aortic mass. Total open surgical excision was performed,which resulted in complete resolution of colitis. Histopathology and immunohistochemistry revealed benign retroperitoneal schwannoma. These neural sheath tumors rarely occur in the retroperitoneum. They are usually asymptomatic but as they enlarge they may compress adjacent structures,which leads to a wide spectrum of non-specific symptoms,including lumbar pain,headache,secondary hypertension,abdominal pain and renal colicky pain. CT and MR findings show characteristic features,but none are specific. Schwannoma can be isolated sporadic lesions,or associated with schwannomatosis or neurofibromatosis type Ⅱ (NF2). Although they vary in biological and clinical behavior,their presence is,in nearly every case,due to alterations or absence of the NF2 gene,which is involved in the growth regulation of Schwann cells. Both conditions were excluded by thorough mutation analysis. Diagnosis is based on histopathological examination and immunohistochemistry. Total excision is therapeutic and has a good prognosis. Schwannomatosis and NF2 should be excluded through clinical diagnostic criteria. Genetic testing of NF2 is probably not justified in the presence of a solitary retroperitoneal schwannoma.Gary Fass Didier Hossey Michel Nyst Dirk Smets Esmail Najar Saligheh Ruth Duttmann Kathleen Claes Pierre Mendes da Costa 2007World Journal of Gastroenterology2007,13,41:5
3Diversity of Helicobacter pylori genotypes in Iranian patients with different gastroduodenal disorders显示文摘AIM:To investigate the diversity of Helicobacter pylori(H.pylori)genotypes and correlations with disease outcomes in an Iranian population with different gastroduodenal disorders.METHODS:Isolates of H.pylori from patients with different gastroduodenal disorders were analyzed after culture and identification by phenotypic and genotypic methods.Genomic DNA was extracted with the QIAamp DNA mini kit(Qiagen,Germany).After DNA extraction,genotyping was done for cagA,vacA(s and m regions),iceA(iceA1,iceA2)and babA with specific primers for each allele using polymerase chain reaction(PCR).All patients’pathologic and clinical data and their relation with known genotypes were analyzed by using SPSS version 19.0 software.2test and Fisher’s exact test were used to assess relationships between categorical variables.The level of statistical significance was set at P<0.05.RESULTS:A total of 71 isolates from 177 patients with different gastroduodenal disorders were obtained.Based on analysis of the cagA gene(positive or negative),vacA s-region(s1or s2),vacA m-region(m1or m2),iceA allelic type(iceA1and iceA2)and babA gene(positive or negative),twenty different genotypic combinations were recognized.The prevalence of cagA,vacA s1,vacA s2,vacA m1,vacA m2,iceA1,iceA2,iceA1+iceA2and babA were 62%,78.9%,19.7%,21.1%,78.9%,15.5%,22.5%,40.8%and 95.8%,respectively.Interestingly,evaluation of PCR results for cagA in 6 patients showed simultaneous existence of cagA variants according to their size diversities that proposed mixed infection in these patients.The most prevalent genotype in cagA-positive isolates was cagA+/vacAs1m2/iceA1+A2/babA+and in cagA-negative isolates was cagA-/vacAs1m2/iceA-/babA+.There were no relationships between the studied genes and histo-pathological findings(H.pylori density,neutrophil activity,lymphoid aggregation in lamina propria and glandular atrophy).The strains which carry cagA,vacAs1/m1,iceA2and babA genes showed significant associations with severe active chronic gastritis(P=0.011,0.025,0.020 and 0.031,respectively).The vacAs1genotype had significant correlation with the presence of the cagA gene(P=0.013).Also,babA genotype showed associations with cagA(P=0.024).In the combined genotypes,only cagA+/vacAs1m1/iceA2/babA+genotype showed correlation with severe active chronic gastritis(P=0.025).CONCLUSION:This genotyping panel can be a useful tool for detection of virulent H.pylori isolates and can provide valuable guidance for prediction of the clinical outcomes.Farzam Vaziri Shahin Najar Peerayeh Masoud Alebouyeh Tabassom Mirzaei Yoshio Yamaoka Mahsa Molaei Nader Maghsoudi Mohammad Reza Zali 2013World Journal of Gastroenterology2013,19,34:5
4Association of Helicobacter pylori infection with acute myocardial infarction显示文摘Zohreh Khodaii Hosain Vakili Sayyed Mohammad Hossein Ghaderian Reza Akbarzadeh Najar Akram Sadat Tabatabaei Panah 2011Coronary Artery Disease2011,,1:2
5浸渍硅胶薄层色谱板分离钴和镍及数字图像分析法定量(英文)显示文摘Thin layer chromatography(TLC) of cobalt and nickel has been performed on silica gel layers induced with alkali mediated cellulose extract.A novel combination of 10% aqueous solutions of Tween-20 and potassium thiocyanate in 1∶1(v/v) was identified as the best mobile phase for the selective separation of Co2+from Ni2+on the impregnated Silica Gel G layers.The chromatographic characteristics of the cations were studied and the limits of detection as well as the limits of quantification for Co2+and Ni2+were determined.The quantitative estimation of the cations was achieved from the digital image analysis of respective chromatograms.The proposed quantitative method was successfully applied with 0-0.50% error for the determination of Co2+from Ni2+in spiked samples of bauxite,soil and rock containing common cations such as Al3+,Fe2+,Ti4+,Zn2+,Mn2+,Cu2+,Cr6+,Mg2+,etc.under the optimized chromatographic conditions.P A MOHAMED NAJAR R G SONALI M T NIMJE K V RAMANA RAO 2012色谱2012,30,10:2
6Computer vision-aided fabric inspection system for on-circular knitting machine 显示文摘Ghazi Saeidi R Latifi M Shaikhzadeh Najar S 2005T R J2005,75,6:1
7Inflammation and toll-like re- ceptor ligation differentially affect the osteogenic potential of human mesenchymal stromal cells depending on their tissue origin显示文摘Raicevic G Najar M Pieters K 2012Tis- sue Eng Part A2012,18,:1
8C-reactive protein (CRP) gene polymorphisms: implication in CRP plasma levels and susceptibility to acute myocardial infarction显示文摘Reza Akbarzadeh Najar Sayyed Mohammad Hossein Ghaderian Akram Sadat Tabatabaei Panah 2012Molecular Biology Reports2012,,4:1
9On the phenomenon of large photoluminescence red shift in GaN nanoparticles 显示文摘Ahmed Ben Slimane Adel Najar Rami Elafandy 2013Nanoscale Research Letters2013,8,342:1
10Inflammation and Toll-like receptor ligation differentially affect the osteogenic potential of human mesenchymal stromal cells depending on their tissue origin显示文摘Raicevic G Najar M Pieters K 2012Tissue Eng Part A2012,18,1314:1
11Genetic polymorphisms and plasma levels of matrix metalloproteinases and their relationships with developing acute myocardial infarction 显示文摘Ghaderian SM Akbarzadeh Najar R Tabatabaei Panah AS 2010Coron Artery Dis2010,21,6:1
12The Traceability in the Agricultural and Food Industry: Stakes, Marks Bench 显示文摘LECOMTE C NAJAR L NEFUSSI J 2003Industries Alimentaires et Agricoles2003,120,5:1
13Mesenchymal stremal ceils use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton's Jelly and bone marrow sourees显示文摘Najar M Raicevic G Boufker HI 2010Cell Immunol2010,264,2:1
14Profile of renal tuberculosis in 63 patients显示文摘Najar MS Bhat MA Wani IA 2003Indian J Nephrol2003,13,:1
15Modulated expression of adhesion molecules and galectin-I : Role during mesenehymalstromal cell immunoregulatory functions显示文摘Najar M Raicevic G Id Bouker H 2010Exp Hematol2010,38,10:1
16The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts显示文摘ID BOUFKER H LAGNEAUX L NAJAR M 2010BMC Cancer2010,10,:1
17Tumor necrosis factor - α : investigation of gene polymorphism and regula- tion of TACE - TNF - α system in patients with acute myocardial infarction显示文摘Ghaderian SM Akbarzadeh Najar R Tabatabaei Panah AS 2011Mol Biol Rep2011,38,8:1
18Bacterial diversity and sulfur cycling in a mesophilic sulfide-rich spring显示文摘Elshahed MS Senko JM Najar FZ 0,,09:1
19Genetic polymorphisms and plasma levels of matrix metalloproteinases and their relationships with developing acute myocardial infarction 显示文摘Ghaderian SM Akbarzadeh Najar R Tabatabaei Panah AS 2010Coron Artery Dis2010,21,6:1
20Involvement of P-glyco-protein and CYP 3A4 in the enhancement of etoposide bioavaila-bility by a piperine analogue显示文摘Najar IA Sharma SC Singh GD 2011Chem Biol Interact2011,190,23:1
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