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| 1 | Short-and long-term results of endoscopic ultrasoundguided transmural drainage for pancreatic pseudocysts and walled-off necrosis显示文摘AIM To evaluate the short-and long-term results of endoscopic ultrasound-guided transmural drainage(EUS-GTD) for pancreatic fluid collection(PFC) and identify the predictive factors of treatment outcome for walled-off necrosis(WON) managed by EUS-GTD alone.METHODS We investigated 103 consecutive patients with PFC who underwent EUS-GTD between September 1999 and August 2015. Patients were divided into four groups as follows: WON(n = 40), pancreatic pseudocyst(PPC; n = 11), chronic pseudocyst(n = 33), and others(n = 19). We evaluated the short-and long-term outcomes of the treatment. In cases of WON, multiple logistic regression analyses were performed to identify the predictor variables associated with the treatment success. In addition, PFC recurrence was examined in patients followed up for more than 6 mo and internal stent removal after successful EUS-GTD was confirmed.RESULTS In this study, the total technical success rate was 96.1%. The treatment success rate of WON, PPC, chronic pseudocyst, and others was 57.5%, 90.9%, 91.0%, and 89.5%, respectively. Contrast-enhanced computed tomography using the multivariate logistic regression analysis revealed that the treatment success rate of WON was significantly lower in patients with more than 50% pancreatic parenchymal necrosis(OR = 17.0; 95%CI: 1.9-150.7; P = 0.011) and in patients with more than 150 mm of PFC(OR = 27.9; 95%CI: 3.4-227.7; P = 0.002).The recurrence of PFC in the long term was 13.3%(median observation time, 38.8 mo). Mean amylase level in the cavity was significantly higher in the recurrence group than in the no recurrence group(P = 0.02).CONCLUSION The reduction of WON by EUS-GTD alone was associated with the proportion of necrotic tissue and extent of the cavity. The amylase level in the cavity may be a predictive factor for recurrence of PFC. | Yuto Watanabe Rintaro Mikata Shin Yasui Hiroshi Ohyama Harutoshi Sugiyama Yuji Sakai Toshio Tsuyuguchi Naoya Kato | 2017 | World Journal of Gastroenterology2017，23，39： | 7 |
| 2 | Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct显示文摘Bile duct epithelial tumours showing papillary neoplasm in the bile duct lumen are present in the intrahepatic and extrahepatic bile ducts.Clinicopathological images of these tumours are distinctive and diverse,including histological images with a low to high grade dysplasia,infiltrating and noninfiltrating characteristics,excessive mucus production,and similarity to intraductal papillary mucinous neoplasm(IPMN)of the pancreas.The World Health Organization Classification of Tumours of the Digestive System in 2010 named these features,intraductal papillary neoplasm of the bile duct(IPNB),as precancerous lesion of biliary carcinoma.IPNB is currently classified into type 1 that is similar to IPMN,and type 2 that is not similar to IPMN.Many of IPNB spreads superficially,and diagnosis with cholangioscopy is considered mandatory to identify accurate localization and progression.Prognosis of IPNB is said to be better than normal bile duct cancer. | Yuji Sakai Masayuki Ohtsuka Harutoshi Sugiyama Rintaro Mikata Shin Yasui Izumi Ohno Yotaro Iino Jun Kato Toshio Tsuyuguchi Naoya Kato | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 3 | Micro RNA ‐148a is downregulated in gastric cancer, targets MMP 7, and indicates tumor invasiveness and poor prognosis显示文摘 | Naoya Sakamoto Yutaka Naito Naohide Oue Kazuhiro Sentani Naohiro Uraoka Htoo Zarni Oo Kazuyoshi Yanagihara Kazuhiko Aoyagi Hiroki Sasaki Wataru Yasui | 2014 | Cancer Sci2014，，2： | 2 |
| 4 | Molecular pathology of gastric cancer: Research and practice显示文摘 | Wataru Yasui Kazuhiro Sentani Naoya Sakamoto Katsuhiro Anami Yutaka Naito Naohide Oue | 2011 | Pathology - Research and Practice2011，，10： | 2 |
| 5 | Changes in the Properties of Anodic Oxidefilms formed on Titanium During Long-term Immersion in Deaerated Neutral Solutions 显示文摘 | KAZUHKISA AZUMI NAOYA YASUI MASHIRO | 2000 | Corrosion Science2000，42，5： | 1 |
| 6 | Liver–intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer显示文摘 | Naoya Sakamoto Naohide Oue Kazuhiro Sentani Katsuhiro Anami Naohiro Uraoka Yutaka Naito Htoo Zarni Oo Takao Hinoi Hideki Ohdan Kazuyoshi Yanagihara Kazuhiko Aoyagi Hiroki Sasaki Wataru Yasui | 2012 | Cancer Sci2012，，9： | 1 |
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