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12篇 您的检索式:作者名="Muscari R"
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1Rescue associating liver partition and portal vein ligation for staged hepatectomy after portal embolization: Our experience and literature review显示文摘AIM To report a single-center experience in rescue associating liver partition and portal vein ligation for staged hepatectomy(ALPPS), after failure of previous portal embolization. We also performed a literature review.METHODS Between January 2014 and December 2015, every patient who underwent a rescue ALPPS procedure in Toulouse Rangueil University Hospital, France, was included. Every patient included had a project of major hepatectomy and a previous portal vein embolization(PVE) with insufficient future liver remnant to body weight ratio after the procedure. The ALPPS procedure was performed in two steps(ALPPS-1 and ALPPS-2), separated by an interval phase. ALPPS-2 was done within 7 to 9 d after ALPPS-1. To estimate the FLR, a computed tomography scan examination was performed 3 to 6 wk after the PVE procedure and 6 to 8 d after ALPPS-1. A transcystic stent was placed during ALPPS-1 and remained opened duringthe interval phase, in order to avoid biliary complications. Postoperative liver failure was defined using the 50-50 criteria. Postoperative complications were assessed according to the Dindo-Clavien Classification.RESULTS From January 2014 to December 2015, 7 patients underwent a rescue ALPPS procedure. Median FLR before PVE, ALPPS-1 and ALPPS-2 were respectively 263 cc(221-380), 450 cc(372-506), and 660 cc(575-776). Median FLR/BWR before PVE, ALPPS-1 and ALPPS-2 were respectively 0.4%(0.3-0.5), 0.6%(0.5-0.8), and 1%(0.8-1.2). Median volume growth of FLR was 69%(18-92) after PVE, and 45%(36-82) after ALPPS-1. The combination of PVE and ALPPS induced a growth of median initial FLR of +408 cc(254-513), leading to an increase of +149%(68-199). After ALPPS-2, 4 patients had stage Ⅰ-Ⅱ complications. Three patients had more severe complications(one stage Ⅲ, one stage Ⅳ and one death due to bowel perforation). Two patients suffered from postoperative liver failure according to the 50/50 criteria. None of our patients developed any biliary complication during the ALPPS procedure.CONCLUSION Rescue ALPPS may be an alternative after unsuccessful PVE and could allow previously unresectable patients to reach surgery. Biliary drainage seems to reduce biliary complications.Charlotte Maulat Antoine Philis Bérénice Charriere Fatima-Zohra Mokrane Rosine Guimbaud Philippe Otal Bertrand Suc Fabrice Muscari 2017World Journal of Clinical Oncology2017,8,4:7
2Contribution of alpha-fetoprotein in liver transplantation for hepatocellular carcinoma显示文摘Alpha-fetoprotein(AFP) is the main tumor biomarker available for the management of hepatocellular carcinoma(HCC). Although it is neither a good screening test nor an accurate diagnostic tool for HCC, it seems to be a possible prognostic marker. However, its contribution in liver transplantation for HCC has not been fully determined, although its use to predict recurrence after liver transplantation has been underlined by international societies. In an era of organ shortages, it could also have a key role in the selection of patients eligible for liver transplantation. Yet unanswered questions remain. First, the cut-off value of serum AFP above which liver transplantation should not be performed is still a subject of debate. We show that a concentration of 1000 ng/m L could be an exclusion criterion, whereas values of < 15 ng/m L indicate patients with an excellent prognosis whatever the size and number of tumors. Monitoring the dynamics of AFP could also prove useful. However, evidence is lacking regarding the values that should be used. Today, the real input of AFP seems to be its integration into new criteria to select patients eligible for a liver transplantation. These recent tools have associated AFP values with morphological criteria, thus refining pre-existing criteria, such as Milan, University of California, San Francisco, or 'up-to-seven'. We provide a review of the different criteria submitted within the past years. Finally, AFP can be used to monitor recurrence after transplantation, although there is little evidence to support this claim. Future challenges will be to draft new international guidelines to implement the use of AFP as a selection tool, and to determine a clear cut-off value above which liver transplantation should not be performed.Bérénice Charrière Charlotte Maulat Bertrand Suc Fabrice Muscari 2016World Journal of Hepatology2016,8,21:3
3Modeling of vortex dynamics in the wake of a marine propeller显示文摘MUSCARI R DI MASCIO A VERZICCO R 2013Computers & Fluids2013,73,6:1
4On the wake dynamics of a propeller operating in drift显示文摘DI MASCIO A MUSCARI R DUBBIOSO G 2014Journal of Fluid Mechanics2014,754,9:1
5Analysis of a marine propeller operating in oblique flow,part 2:very high incidence angles显示文摘Dubbioso G Muscari R Mascio A D 2014Computers&Fluids2014,92,:1
6Posttraumatic Pseudoaneurysm of the Hepatic Artery: Treatment with Ultrasound-Guided Percutaneous Transhepatic Thrombin Injection显示文摘Camille Dambrin Bertrand Marcheix Tudor Birsan Christophe Cron Fabrice Muscari Bertrand Suc Alain Cérène Hervé Rousseau 2005The Journal of Trauma: Injury, Infection, and Critical Care2005,,1:1
7CO as an important high altitude tracer of dynamics in the polar stratosphere and mesosphere显示文摘de Zafra R L Muscari G 0,,:1
8Blood pressure and intellectual function in elderly subjects显示文摘Palombo V Scurti R Muscari A 1997Age Aging1997,26,2:1
9Blood presure and intellectual function in elderly subjects显示文摘Palombo V Scurti R Muscari A 1997Age and Ageing1997,26,:1
10On the application of the single-phase level set method to na val hydrodynamics flows显示文摘MASCIO A D BROGLIA R MUSCARI R 2007Computers & Fluids2007,,36:1
11Mod eling of vortex dynamics in the wake of a marine pro peller显示文摘MUSCARI R MASCIO A D VERZICCO R 2013Computers & Fluids2013,73,:1
12Blood pressure and intellectual function in elderly subjects显示文摘PALOMBO V SCURTI R MUSCARI A 1997Age Ageing1997,26,2:1
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