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| 1 | Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis显示文摘 | Rosa M. Pascale Maria M. Simile Maria R. De Miglio Maria R. Muroni Diego F. Calvisi Giuseppina Asara Daniela Casabona Maddalena Frau Maria A. Seddaiu Francesco Feo | 2002 | Hepatology2002，，6： | 1 |
| 2 | One-step laparoscopic and endoscopic treatment of gallbladder and common bile duct stones : our experience of the last 9 years in a retrospective study 显示文摘 | Liverani A Muroni M Santi F | 2013 | Am Surg2013，79，12： | 1 |
| 3 | Synchronous gastric adenocarcinoma and pancreatic ductal adenocarcinoma显示文摘BACKGROUND:The association between gastric and pancreatic carcinoma is a relatively rare condition.In gastric carcinoma patients,the prevalence of second tumors varies 2.8% to 6.8% according to the reported statistics.Gastric cancer associated with pancreatic cancer is uncommon.METHODS:We report a case of a 73-year-old patient hospitalized for vomiting and weight loss.Esophagogastroduodenoscopy demonstrated an ulcerative lesion of the gastric antrum.Computed tomography and magnetic resonance showed a gastric thickening in the antral and pyloric portion and a nodular mass (3×1.7 cm) in the uncinate portion of the pancreas.RESULTS:The patient underwent pancreaticoduoden-ectomy according to Whipple regional type Ⅰ Fortner.Histological examination of the specimen demonstrated a moderately differentiated adenocarcinoma of the stomach and a poorly differentiated ductal adenocarcinoma of the pancreas.CONCLUSIONS:Long survival is rare in patients with associated gastric and pancreatic cancer.Surgical resection remains the only potentially curative treatment. | Mirko Muroni Francesco D'Angelo Massimo Pezzatini Simone Sebastiani Samantha Noto Emanuela Pilozzi Giovanni Ramacciato | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，1： | 1 |
| 4 | Down - regulation of c-mye and cyelinDl genes by antisense oli- godeoxy nueleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells显示文摘 | Simile MM De Miglio MR Muroni MR Frau M Asara G Ser- ra S Muntoai MD Seddaiu MA Daino L Feo F Pascale RM | 2004 | Carcino- genesis2004，25，3： | 1 |
| 5 | Down-regulation of c- myc and Cyclin D1 genes by antisense oligodeoxy nucleotides in- hibits the expression of E2F1 and in vitro growth of HepG2 ang Morris 5123 liver cancer ceils 显示文摘 | Simile M M Miglio M R Muroni M R | 2004 | Carcinogenesis2004，25，3： | 1 |
| 6 | Implication of Bcl-2 family genes in basal and D-amphetamine-induced apoptosis in preneoplastic and neoplastic rat liver lesions显示文摘 | De Miglio MR Muroni MR Simile MM | 2000 | Hepatology2000，31，4： | 1 |
| 7 | Frequent loss of heterozygosity at the Hcrl ( hepatocarcinogenesis resistance) locus on chromosome 10 in primary hepatocellular carcinomas from LFF1 rat strain 显示文摘 | De Miglio MR Muroni MR Simile MM | 2001 | Hepatology2001，33，5： | 1 |
| 8 | Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells显示文摘 | Simile MM Miglio MR Muroni MR | 2004 | Carcinogenesis2004，25，3： | 1 |
| 9 | Implication of Bcl-2 family genes in basal and D-amphetamine-induced apoptosis in preneoplasticand neoplastic rat liver lesions显示文摘 | De Miglio MR Muroni MR Simile MM | 2000 | Hepatology2000，31，： | 1 |
| 10 | Down-regulation of c-myc and CyclinD1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F and in ritro growth of HepG2 and Morris 5123 liver cancer cells 显示文摘 | Simile MM Miglio MR Muroni MR | 2004 | Carcinogennesis2004，25，3： | 1 |
| 11 | Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nuclcotides inhibits the expression of E2F1 and in vitro growth of Hep G2 and Morris5123 liver cancer cells显示文摘 | SIMILE MIGLUO DE MR MURONI MR | 2004 | Carcinoge-nesis2004，25，3： | 1 |
| 12 | Pancreas-preserving segmental duodenectomy for gastrointestinal stromal tumor of the duodenum and splenectomy for splenic angiosarcoma显示文摘BACKGROUND: Gastrointestinal stromal tumors are the most common mesenchymal tumors of the gastrointestinal tract and occur rarely in the duodenum. Splenic angiosarcoma is an aggressive neoplasm with an extremely poor prognosis. METHODS: We report a case of a 70-year-old man hospitalized for abdominal pain in the upper quadrants, dyspepsia and nausea, previously treated for Hodgkin lymphoma 30 years ago. Abdominal CT showed a solid nodular lesion in the third portion of the duodenum, the presence of retropancreatic, aortic and caval lymph nodes, and four nodular splenic masses. 111 In-octreotide scintigraphy revealed pathological tissue accumulation in the duodenal region, and in the retropancreatic, retroduodenal, aortic and caval lymph nodes, suggesting a nonfunctioning neuroendocrine peripancreatic tumor. RESULTS: At exploratory laparotomy, an exophytic soft tumor was found originating from the third portion of the duodenum. Pancreas-preserving duodenectomy with duodenojejunostomy, splenectomy and lymphnodectomy of retropancreatic aortic and caval lymph nodes were performed. Pathological evaluation and immunohistochemical studies showed the presence of a duodenal gastrointestinal stromal tumor with low mitotic activity and a well-differentiated angiosarcoma localized to the spleen and invading lymph nodes.CONCLUSIONS: We speculated that the angiosarcoma and duodenal gastrointestinal stromal tumors of this patient were due to the treatment of Hodgkin lymphoma with radiotherapy 30 years ago. Pancreas-preserving segmental duodenectomy can be used to treat non-malignant neoplasms of the duodenum and avoid extensive surgery. Splenectomy is the treatment of choice for localized angiosarcomas but a strict follow-up is mandatory because of the possibility of recurrence. | Mirko Muroni Matteo Ravaioli Massimo Del Gaudio Giuseppe Nigri Francesco D'Angelo Stefania Uccini Giovanni Ramacciato | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 1 |
| 13 | Analysis of PIK3CA Mu- tations and Activation Pathways in Triple Negative Breast Cancer显示文摘 | Cossu-Rocca P Orr0 S Muroni MR | 2015 | PLoS One2015，10，01： | 1 |
| 14 | Down-regulation of c-myc and Cyclin Dl genes by antisense oligodeoxy nucleotides inhibits the expression of E2Fl and in vitro growth of HepG2 and Morris 5123 liver cancer cells显示文摘 | Simile MM De Miglio MR Muroni M R | 2004 | Carcinogenesis2004，25，3： | 1 |
| 15 | Transferrin and transferrin receptor gene expression and iron uptake in hepatocellular carcinoma in the rat显示文摘 | Pascale RM De Miglio MR Muroni MR | | 0，，02： | 1 |
| 16 | Frequent loss of heterozygosity at the Hcrl (hepatocarcinogenesis resistance) locus on chromosome 10 in primary hepatocellular carcinomas from LFF1 rat strain显示文摘 | DE MIGLIO MR MURONI MR SIMILE MM | 2001 | Hepatology2001，33，5： | 1 |
| 17 | Down-regulation of cmyc and cyclinD1 genes by antisense oligodeoxy nucleofides inhibits the expression of E2F and in vitro growth of HepG2 and Morris5123 liver cancer cells显示文摘 | Simile MM Miglio MR Muroni MR | 2004 | Carcinogennesis2004，25，3： | 1 |
| 18 | One-step laparoscopic and endoscopic treatment of gallbladder and common bile duct stones:our experience of the last 9 years in a retrospective study 显示文摘 | Liverani A Muroni M Santi F | 2013 | Am Surg2013，79，12： | 1 |
| 19 | Down-regulation of c-myc and cyclinD1 genes by antisense oliodeoxy nucleotides inhibits the expression of E2 F and in ritro growth of HepG2and Morris 5123 liver cancer cells显示文摘 | Simile MM Miglio MR Muroni MR | 2004 | Carcinogennesis2004，25，3： | 1 |
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