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您的检索式：作者名="Muhammad A Abbas"
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| 1 | Pam3CSK4 enhances adaptive immune responses to recombinant Mycobacterium bovis bacille Calmette-Guérin expressing Plasmodium falciparum C-terminus merozoite surface protein-1显示文摘Objective: To determine the effects of toll-like receptor 2(TLR-2) agonist, Pam3 CSK4, on cellular and humoral immune response against recombinant Mycobacterium bovis bacille Calmette-Guérin(rBCG) expressing the C-terminus of merozoite surface protein-1 of Plasmodium falciparum.Methods: Six groups of mice(n=6 per group) received intraperitoneal phosphate buffered saline T80(PBS-T80), BCG or rBCG in the presence or absence of Pam3 CSK4. Enzymelinked immunosorbent assay was carried out to measure serum total IgG, IgG1, IgG2 a, and Ig G2 b production. Spleens were also harvested and splenocytes were co-cultured with rBCG antigen for in vitro determination of IL-4 and IFN-γ via enzyme-linked immunosorbent assay.Results: The production of total IgG and the isotype IgG1, IgG2 a and IgG2 b was significantly higher in rBCG-immunised mice than in the BCG and PBS-T80-immunised mice, and Pam3 CSK4 further enhanced their productions. A similar pattern was also observed in IFN-γ production. Moreover, there was no significant difference in IL-4 production in all groups either in the presence or absence of Pam3 CSK4.Conclusions: We present evidence of the adjuvant effects of TLR-2 agonist in enhancing the production of total IgG, IgG1, IgG2 a, IgG2 b, as well as IFN-γ in response to rBCG. However, the presence or absence of Pam3 CSK4 had no effect on IL-4 production. | Mohamed H Abdikarim Muhammad A Abbas Munirah N Zakaria Robaiza Zakaria Rapeah Suppian | 2019 | Asian Pacific Journal of Tropical Biomedicine2019，9，7： | 3 |
| 2 | The production of dry powder by the sonocrystallisation for inhalation drug delivery 显示文摘 | Muhammad S Oubani H Abbas A | 2013 | Powder Technol2013，246，9： | 1 |
| 3 | Biological characteristics and host stage preference of mealybug parasitoid Aenasius bambawalei Hayat (Hymenoptera:Encyrtidae)显示文摘 | Zainul-Abdin AM J Gogi MD Muhammad A Fiaz H Abbas SK Hoor S Atif M | | 0，，01： | 1 |
| 4 | Dry reforming of methane : influence of process parame- ters a review 显示文摘 | Muhammad Usman Wan Daud W M A Hazzim F Abbas | 2015 | Renewable and Sustainable Energy Reviews2015，45，5： | 1 |
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