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| 1 | PEComa of the colon resistant to sirolimus but responsive to doxorubicin/ifosfamide显示文摘A 23-year-old male presented with a three-week-history of crampy abdominal pain and melaena.Colonoscopy revealed a friable mass filling the entire lumen of the cecum;histologically,it was classified as perivascular epithelioid cell tumor(PEComa).An magnetic resonance imaging scan showed,in addition to the primary tumor,two large mesenteric lymph node metastases and four metastatic lesions in the liver.The patient underwent right hemicolectomy and left hemihepatectomy combined with wedge resections of metastases in the right lobe of the liver,the resection status was R0.Subsequently,the patient was treated with sirolimus.After 4 mo of adjuvant mammalian target of rapamycin inhibition he developed two new liver metastases and a local pelvic recurrence.The visible tumor formations were again excised surgically,this time the resection status was R2 with regard to the pelvic recurrence.The patient was treated with 12 cycles of doxorubicin and ifosfamide under which the disease was stable for 9 mo.The clinical course was then determined by rapid tumor growth in the pelvic cavity.Second line chemotherapy with gemcitabine and docetaxel was ineffective,and the patient died 23 mo after the onset of disease.This case report adds evidence that,in malignant PEComa,the mainstay of treatment is curative surgery.If not achievable,the effects of adjuvant or palliative chemotherapy are unpredictable. | Wolfgang Scheppach Nikolaus Reissmann Thomas Sprinz Ekkehard Schippers Bjoern Schoettker Justus G Mueller | 2013 | World Journal of Gastroenterology2013，19，10： | 8 |
| 2 | Machine-learned multi-system surrogate models for materials prediction显示文摘Surrogate machine-learning models are transforming computational materials science by predicting properties of materials with the accuracy of ab initio methods at a fraction of the computational cost.We demonstrate surrogate models that simultaneously interpolate energies of different materials on a dataset of 10 binary alloys(AgCu,AlFe,AlMg,AlNi,AlTi,CoNi,CuFe,CuNi,FeV,and NbNi)with 10 different species and all possible fcc,bcc,and hcp structures up to eight atoms in the unit cell,15,950 structures in total.We find that the deviation of prediction errors when increasing the number of simultaneously modeled alloys is<1 meV/atom.Several state-of-the-art materials representations and learning algorithms were found to qualitatively agree on the prediction errors of formation enthalpy with relative errors of<2.5% for all systems. | Chandramouli Nyshadham Matthias Rupp Brayden Bekker Alexander V.Shapeev Tim Mueller Conrad W.Rosenbrock Gábor Csányi David W.Wingate Gus L.W.Hart | 2019 | npj Computational Materials2019，，1： | 8 |
| 3 | Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study显示文摘 | Andri Rauch Zoltán Kutalik Patrick Descombes Tao Cai Julia Di Iulio Tobias Mueller Murielle Bochud Manuel Battegay Enos Bernasconi Jan Borovicka Sara Colombo Andreas Cerny Jean–Fran?ois Dufour Hansjakob Furrer Huldrych F. Günthard Markus Heim Bernard Hirs | 2010 | Gastroenterology2010，，4： | 2 |
| 4 | CEO characteristics and firm R&D spending显示文摘 | BARKER V G MUELLER | 2002 | Management Science2002，48，6： | 1 |
| 5 | Intraoperative high-dose anti-Tlymphocyte globulin bolus in addition to triple-drug therapy improves kidney graft survival显示文摘 | Kaden J May G Mueller P | | 0，，01： | 1 |
| 6 | Macrofungal diversity of a temperate oak forest:a test of species richness estimators显示文摘 | Schmit P J Murphy J F Mueller G M | | 0，，07： | 1 |
| 7 | Affect and creativity at work显示文摘 | Amabile T M Barsade S G Mueller J S and Staw B M | 2005 | Administrative Science Quarter- ly2005，50，3： | 1 |
| 8 | The chemokine receptor,CCR5显示文摘 | Mueller A Strange P G | 2004 | Int J Biochem Cell Biol2004，36，1： | 1 |
| 9 | Industrial Research and Development, Intangible Capital Stocks, and Firm Profit Rates 显示文摘 | Grabowski H G D C Mueller | 1978 | The Bell Journal of Economics1978，9，2： | 1 |
| 10 | Embryonic critical windows: changes in incubation temperature alter survival, hatchling phenotype, and cost of development in lake whitefish (Coregonus clupeaformis) 显示文摘 | Mueller C A Eme J Manzon R G | 2015 | J Comp Physiol B2015，185，： | 1 |
| 11 | Outcomes of patients with definite and suspected isolated cardiac sarcoidosis treated with an implantable cardiac defibrillator 显示文摘 | Kron J Saner W Mueller G | 2015 | J Interv Card Eleclrophysiol2015，43，1： | 1 |
| 12 | Effect of SiO2 on densification and microstructure development in Nd:YAG transparent ceramics 显示文摘 | STEVENSON A J LI Xin MART1NEZ M A ANDERSON J M SUCHY D L KUPP E R DICKEY1 Z C MUELLER K T MESSING G L | 2011 | J Am Ceram Soc2011，94，： | 1 |
| 13 | Perioperative prediction by MRI of prostate volume six to twelve months after laser-induced thermotherapy of benign prostatic hyperplasia显示文摘 | Ullrich G Mueller Markus F | 2001 | JMRI2001，13，： | 1 |
| 14 | Displacement of estradiol from estrogen receptors by simplealkylphenols显示文摘 | Mueller G C | 1978 | Endocrine1978，102，5： | 1 |
| 15 | Prevention of contrast me- dia associated nephropathy: randomized comparison of hydration regimens in 1620 patients undergoing coronary angioplasty 显示文摘 | Mueller C Buerkle G Buettner HJ | 2002 | Arch Intern Med2002，162，3： | 1 |
| 16 | The eddects of antiscalants on fouling of cooling Water显示文摘 | Libuttil Knudsen J G Mueller R W | 1984 | Material PerformanCr1984，23，11： | 1 |
| 17 | Different Structural Correlates for Verbal Memory Impairment in Temporal Lobe Epilepsy with and Without Mesial Temporal Lobe Sclerosis 显示文摘 | MUELLER S G LAXER K D SCANLON C | 2012 | Hum Brain Mapp2012，33，2： | 1 |
| 18 | Structure and function of claudins显示文摘 | Krause G Winkler L Mueller SL | 2008 | Biochim Biophys Acta2008，1778，3： | 1 |
| 19 | CEO Character- istics and Firm RD Spending显示文摘 | BARKER III V L MUELLER G C | 2002 | Management Sci- ence2002，48，6： | 1 |
| 20 | Influence of particle fluxes from a target on the characteristics of intense electron beams显示文摘 | Engelko V Mueller G | 2001 | Vacuum2001，62，： | 1 |
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