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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Relation between the viscoelastic and Flammability properties of Polymer nanocomposites显示文摘 | Kashiwagi T Mu M F Winey K | 2008 | Polymer2008，49，： | 1 |
| 3 | Development of a global evapotranspiration algorithm based on MODIS and global meteorology data显示文摘 | Mu Q Z Heinseh F A Zhao M | 2007 | Remote Sensing of Environment2007，111，： | 1 |
| 4 | Evaluating water stress controls on primary production in biogeochemical and remote sensing based models显示文摘 | Mu Q Zhao M Hemsch F A | 2007 | Journal of Geophysical Research2007，，： | 1 |
| 5 | Measuring soluble platelet glycoprotein VI in human plasma by E LISA显示文摘 | Al-Tamimi M Mu F T Moroi M | 2009 | Platelets2009，20，3： | 1 |
| 6 | Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory显示文摘 | Liu F Day M Muiz LC | 2008 | Nat Neurosci2008，11，3： | 1 |
| 7 | Ultrasonic irradiation in the enzymatic extraction of collagen 显示文摘 | Li D F Mu C D Cai S M | 2009 | Ultrasonics sonochemistry2009，16，5： | 1 |
| 8 | Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up显示文摘ObjectiveTo 评估立即的 transcatheter 在有严重、征兆的大动脉的狭窄的很老的病人的大动脉的阀门培植(TAVI ) 结果和中期的后续(作为).MethodsThis multicenter,观察、未来的学习在三所医院里被执行。我们包括了连续很老(>85 年) 病人与作为严重由 TAVI 对待。主要端点是在包括的二 years.ResultsThe 研究从任何原因评估死亡率有一个平均数的 160 个连续病人 87 ± 变老;2.1 年(从 85 ~ 94 年的范围) 和 18.8%± 的吝啬的逻辑 EuroSCORE;11.2% 与 57 (35.6%) 病人得分 ≥20% 。程序的成功率是 97.5% ,与 25 (15.6%) 与主要流血经历尖锐复杂并发症的病人(最经常) 。全球死亡率在住院期间是 8.8%(n = 14 ) 并且 30 天的死亡率是 10%(n = 16 ) 。中部在时期上面列在后面是 252.24 ±232.17 天。在后续时期期间, 28 (17.5%) 病人们死了(他们中的 17 个由于心脏的原因) 。估计的二年全面、心脏的幸存率使用 Kaplan-Meier 方法分别地是 71% 和 86.4% 。比例的危险回归给看了的考克斯可变 EuroSCORE ≥20 是与全面 mortality.ConclusionsTAVI 联系的唯一的变量在很老的病人的一张选择人口安全、有效。我们的调查结果支持在病人的这个复杂的组的这个新过程的采纳。 | Isaac Pascual Antonio J Mu oz-García Diego López-Otero Pablo Avanzas Manuel F Jimenez-Navarro Belén Cid-Alvarez Raquel del Valle Juan H Alonso-Briales Raimundo Ocaranza-Sanchez José M Hemández Ramiro Trillo-Nouche César Morís | 2015 | Journal of Geriatric Cardiology2015，12，4： | 1 |
| 9 | Acidic solution properties ofy9-casein-graft-dextran copolymer prepared through Maillard reaction显示文摘 | MU M F PAN X Y YAO P | 2006 | Journal of Colloid and Interface Science2006，301，1： | 1 |
| 10 | Development of a global evapotranspiration algorithm based on MODIS and global meteorology data 显示文摘 | Mu Q Z Heinsch F A Zhao M S | 2007 | Remote Sensing of Environment2007，111，4： | 1 |
| 11 | Subspace analysis of spatial time-frequency distribution matrices 显示文摘 | Zhang Y M Mu W F Amin M G | 2001 | IEEE Transactions on Signal Processing2001，49，4： | 1 |
| 12 | Genome sequence and analysis of the tuber crop potato显示文摘 | Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G | 2011 | Nature2011，475，7355： | 1 |
| 13 | An evaluation of JPCP faulting and transverse cracking models of the mechanistic-empirical pavement design guide显示文摘 | MU F VANDENBOSSCHE J M GATTI K A | 2012 | Road Materials and Pavement Design2012，13，1： | 1 |
| 14 | De Novo Characterization of the spleen transcriptome of the large yellow croaker( Pseudosciaena crocea)and analysis of the immune relevant genes and pathways involved in the antiviral response 显示文摘 | Mu Y Li M Ding F | 2014 | PLOS ONE2014，9，97： | 1 |
| 15 | Uniform Rotational Motion Compensation for Inverse Synthetic Aperture Radar with Non-cooperative Targets显示文摘 | Mu(n)oz-Ferreras J M Pérez-Martínez F | 2008 | IET Radar Sonar Navig2008，2，1： | 1 |
| 16 | A d-psicose 3-epimerase with neutral pH optimum from clostridium bolteae for d-psicose production:cloning,expression,purification,and characterization显示文摘 | Jia M Mu W Chu F | 2014 | Applied Microbiology and Biotechnology2014，98，2： | 1 |
| 17 | Influence of rare el- ement on microstructure and mechanical properties of cast high-speed steel rolls 显示文摘 | Wang M J Mu S M Sun F F | 2007 | Journal of Rare Earths2007，25，： | 1 |
| 18 | Nano-silicon carbide supported catalysts for PEM fuel cells with high electrochemical stability and improved performance by addition of carbon显示文摘 | LV H'F MU S C CHENG N C PAN M | 2010 | Appl Catal B:Environ2010，100，12： | 1 |
| 19 | Study on microstructure and properties of aged Cu-Cr-Zr--Mg-RE alloy 显示文摘 | MU S G GUO F A TANG Y Q CAO X M TANG M T | 2008 | Mater Sci Eng A2008，475，12： | 1 |
| 20 | Activation of estrogen receptor-be-ta regulates hippocampal synaptic plasticity and improves memory显示文摘 | Liu F Day M Muiz LC | 2008 | Nat Neurosci2008，11，： | 1 |
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