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122篇 您的检索式:作者名="Moorthy R"
    题名 作者 年代 出处 被引量
1Preparation and characterization of curcumin-piperine dual drug loaded nanoparticles显示文摘Objective:To prepare curcumin-piperine(Cu-Pi) nanoparticles by various methods and to study the effect of various manufacturing parameters on Cu-Pi nanoparticles and to identify a suitable method for the preparation of Cu-Pi nanoparticles to overcome oral bioavailability and cancer cell targeting limitations in the treatment of cancer.Methods:Cu-Pi nanoparticles were prepared by thin film hydration method,solid dispersion method,emulsion polymerization method and Fessi method.Optimization was carried out to study the effect of various manufacturing parameter on the Cu-Pi nanoparticles.Results:Out of four methods,Fessi method produced a minimum average particle size of 85.43 nm with a polydispersity index of 0.183 and zeta potential of 29.7 mV.Change of organic solvent(acetone or ethanol) did not have any significant effect on Cu-Pi nanoparticles.However,increase in sonication time,stirring speed,viscosity,use of 1:10:10 ratio of drag/polymer/surfactant,and use of anionic surfactant or combination of anionic surfactant with cationic polymer or combination of non-ionic surfactant with cationic polymer had a significant effect on Cu-Pi nanoparticles.Conclusions:Cu-Pi nanoparticles coated with PEC containing copolymer produced by Fessi method had a minimum average particle size,excellent polydispersity index and optimal zeta potential which fall within the acceptable limits of the study.This dual nanoparticulate drug delivery system appears to be promising to overcome oral bioavailability and cancer cell targeting limitations in the treatment of cancer.C Moorthi Kiran Krishnan R Manavalan K Kathiresan 2012Asian Pacific Journal of Tropical Biomedicine2012,2,11:3
2Managing a distribution channel under asymmetric information with performation with performance requirements显示文摘Desiraju R Moorthy S 1997Management Science1997,43,12:1
3Branding in developing markets显示文摘Keller K L Moorthi Y L R 2003Business Horizons2003,46,3:1
4Retrieving crown leaf area index from an individual tree using ground-based lidar data显示文摘Moorthy I Miller J R 2008Canadian Journal of Remote Sensing2008,34,3:1
5Berth management in container terminal: the template design problem显示文摘Moorthy R Teo C 2006OR Spectrum2006,28,:1
6EPR and electron absorption spectra of copper bearing turquoise mineral 显示文摘Sharma K B N Moorthy L R Reddy B J 1988Phys Lett A1988,132,:1
7Managing a distribution channel under asymmetric information with performance requirements显示文摘Desiraju R Moorthy S 1997Management Science1997,43,:1
8Laparoscopic skills training and assessment 显示文摘Aggarwal R Moorthy K Darzi A 2004British Journal of Surgery2004,,91:1
9Managing a distribution channel under asymmetric information with performance re- quirements 显示文摘Desiraju R Moorthy S 1997Management Science1997,43,12:1
10Smad4 regulates elaudirr 1 expression in a transforming growth factor beta independent manner in colon cancer cells显示文摘Shion S R singh A B Moorthy K 2007Cancer Res2007,67,4:1
11Laparoscopic skills training and assessmen显示文摘Aggarwal R Moorthy K Darzi A 2004Br J Surg2004,,91:1
12Cyclic deadlock prediction and avoidance for zone-con- trolled AGV system 显示文摘MOORTHY R HOCK-GUAN W WING-CHEONG N 2003International Journal of Production Economics2003,83,3:1
13Resolving carbonate complexi ty显示文摘A1-Marzouqi ML Budebes I Griffiths R Gzara K Rama- moorthy R Husser A 2010Oilfield Review2010,22,2:1
14A comparison of plasma and muscle carnitine levels in patients on peritoneal or hemodialysis for chronic renal failure显示文摘MOORTHY A V ROSENBLUM M RAJARAM R 1983Am J Nephrol1983,3,4:1
15A comparison of plasma and muscle carntine levels in patients on peritoneal or hemodialysis for chronic renal railure显示文摘Moorthy A Rosenblum M R ajaram R 1983Am J Neprol1983,3,:1
16Nontuberculous mycobacterial ocular and adnexal infections显示文摘Moorthy R S Valluri S Rao N A 0,,03:1
17Managing a distribu-tion channel under asymmetric information with per-formance requirements显示文摘DESIRAJU R MOORTHY S 1997Management Science1997,43,12:1
18Estimating chlorophyll concentration in conifer needles with hyperspectral data:an assessment at the needle and canopy level显示文摘Moorthy I Miller J R Noland T L 2008Remote Sensing of Environment2008,112,6:1
19Mucosal immunization of mice with malaria protein on lactic acid bacterial cell walls显示文摘Moorthy G Ramasamy R 2007Vaccine2007,25,18:1
20Left supraclavicular spindle cell lipoma 显示文摘Olaleye O Fu B Moorthy R 2010Int J Otolaryngol2010,25,94:1
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