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| 1 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016,19,9: | 10 |
| 2 | Systems biology approaches for studying the pathogenesis of non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD) is a progressive disease of increasing public health concern.In western populations the disease has an estimated prevalence of 20%-40%,rising to 70%-90% in obese and type Ⅱ diabetic individuals.Simplistically,NAFLD is the macroscopic accumulation of lipid in the liver,and is viewed as the hepatic manifestation of the metabolic syndrome.However,the molecular mechanisms mediating both the initial development of steatosis and its progression through non-alcoholic steatohepatitis to debilitating and potentially fatal fibrosis and cirrhosis are only partially understood.Despite increased research in this field,the development of non-invasive clinical diagnostic tools and the discovery of novel therapeutic targets has been frustratingly slow.We note that,to date,NAFLD research has been dominated by in vivo experiments in animal models and human clinical studies.Systems biology tools and novel computational simulation techniques allow the study of large-scale metabolic networks and the impact of their dysregulation on health.Here we review current systems biology tools and discuss the benefits to their application to the study of NAFLD.We propose that a systems approach utilising novel in silico modelling and simulation techniques is key to a more comprehensive,better targeted NAFLD research strategy.Such an approach will accelerate the progress of research and vital translation into clinic. | Ciarán P Fisher Andrzej M Kierzek Nick J Plant J Bernadette Moore | 2014 | World Journal of Gastroenterology2014,20,41: | 2 |
| 3 | Corrosion protection of magnesium by electroactive polypyrrole/paint coatings显示文摘 | Truong V T Lai P K Moore B T | 2000 | Synthetic Metals2000,111,: | 2 |
| 4 | Therapeutic use of etanercept in polyarticular course juvenile idiopathic arthritis over a two year period显示文摘 | Kietz D A Pepmueller P H Moore T L | 2002 | Ann Rheum Dis2002,61,2: | 1 |
| 5 | The management of ascites in cirrhosis : report on the consensus conference of the international ascite club 显示文摘 | Moore KP Wong F Gines P | 2003 | Hepatology2003,38,1: | 1 |
| 6 | Association between polysomnographic sleep measures and health-related quality of life in obstructive sleep apnea显示文摘 | Moore P Bardwell W A Ancoli-Israel S | 2001 | J Sleep Res2001,10,4: | 1 |
| 7 | The percutaneous absorption of lead-203 in humans from cosmetic preparations containing lead acetate, as assessed by whole-body counting and other techniques 显示文摘 | Moore M Meredith P Watson W | 1980 | Food and Cosmetics Toxicology1980,18,: | 1 |
| 8 | The impact of behavior and addiction on psychological models of cigarette and alcohol use during pregnancy显示文摘 | Moore P J Turner R Park C L | 1996 | Addictive Behavior1996,21,5: | 1 |
| 9 | Effect of chemical amendments on ammonia volatilization from poultry litter显示文摘 | Moore P A J Daniel T C Edwards D R | 1995 | Journal of Environmental Quality1995,24,: | 1 |
| 10 | The development and application of genetic markers for the Kuruma prawn Penaeus japonicus显示文摘 | Moore S S Whan V Davis G P | 1999 | Aquaculture1999,173,14: | 1 |
| 11 | Modularity,strategic flexibility,and firm performance:A study of the home appliance industry显示文摘 | WORREN N MOORE K CARDONA P | 2002 | Strategic Management Journal2002,,23: | 1 |
| 12 | Predictive value of cell cycle markers p53,mdm2,p21 and ki-67 in superficial bladder tumor recurrence显示文摘 | Pfister C Moore L Allard P | 1999 | Clin Cancer Res1999,5,: | 1 |
| 13 | Corrosion behavior of laser-surface melted and laser-surface alloyed steels 显示文摘 | Mcafferty E Moore P G | 1986 | Journal of the Electrochemical Society1986,133,6: | 1 |
| 14 | GMP -140, a platelet alph a granule membrane protein is also synthesized by vascular endothelial cells and islocalized in Weibel - Palade bodies显示文摘 | MCEVER R P BECKSTEAD J H MOORE K L | 1989 | J Clin Invest1989,84,1: | 1 |
| 15 | Improved distal distribution of n - butyl cyanoacrylate glue by simultaneous injection of dextrose 5 through the guiding catheter: Technical note显示文摘 | Moore C Murphy K Gailloud P | 2006 | Neuroradiology2006,48,: | 1 |
| 16 | Differential gene expression following early renal ischemia/reperfusion 显示文摘 | Supavekin S Zhang W Kucherlapati R Kaskel F J Moore L C Devarajan P | 2003 | Kid Int2003,63,: | 1 |
| 17 | Invasive Pneumococcal Disease in Children 5 Years After Conjugate Vaccine Introduction - Eight States, 1998-2005显示文摘 | Reingold A Hadler J Farley M M Harrison L Lynfield R Lexau C Bennett N Thomas A Craig A S Smith P J Beall B Whitney C G Moore M Pilishvili T | 2008 | MMWR Morbidity and Mortality Weekly Report2008,,6: | 1 |
| 18 | The trouble with overconfidence 显示文摘 | MOORE D HEALY P | 2008 | Psy- chological Review2008,115,2: | 1 |
| 19 | The Lessons We (don't) Learn : Counterfactual Thinking and Organizational Accountability After a Close Call 显示文摘 | Morris M W Moore P C | 2000 | Administrative Science Quarterly2000,45,12: | 1 |
| 20 | Network formation in gluten - free bread with application of transglutaminase 显示文摘 | Moore M Heinbockel M Dockery P | 2006 | Cereal chemistry2006,83,1: | 1 |