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| 1 | Double-balloon endoscopy in the diagnosis and management of GI tract diseases:Methodology,indications,safety,and clinical impact显示文摘AIM: To prospectively evaluate the indications, method-ology, safety, and clinical impact of double-balloon en-doscopy.METHODS: A total of 60 patients with suspected or documented small- or large-bowel diseases were investi-gated by double balloon endoscopy. A total of 103 proce-dures were performed (42 from the oral route, 60 from the anal route, and 1 from the stoma route). The main outcome measurements were the time of insertion and the entire examination, complications, diagnostic yields, and the ability to successfully perform treatment.RESULTS: Observation of the entire small intestine was possible in 10 (40%) of 25 patients with total enteros-copy. The median insertion time was 122 min (range, 74-199 min). Observation of the entire colon was possi-ble in 13 (93%) of 14 patients after failure of total colo-noscopy using a conventional colonoscope. Small-intes-tine abnormalities were found in 20 (43%) of 46 patients with indications of suspected or documented small bowel diseases, obscure GI tract bleeding, or a history of ileus. Endoscopic procedures including tattooing (n = 33), bite biopsy (n = 17), radiographic examination (n = 7), EUS (n = 5), hemostasis (n = 1), polypectomy (n = 5), balloon dilatation (n = 1), endoscopic mucosal resection (n = 1) and lithotripsy (n = 1) were all successfully performed. No relevant technical problems or severe complications were encountered.CONCLUSION: Double balloon endoscopy is a feasible technique that allows adequate small and large bowel examination and potentially various endoscopic proce-dures of small-intestinal lesions. It is safe, useful, and also provides a high clinical impact. | Kazuya Akahoshi Masaru Kubokawa Masahiro Matsumoto Shingo Endo Yasuaki Motomura Jiro Ouchi Mitsuhide Kimura Atsuhiko Murata Michiaki Murayama | 2006 | World Journal of Gastroenterology2006，12，47： | 8 |
| 2 | Safety advantage of endocut mode over endoscopic sphincterotomy for choledocholithiasis显示文摘瞄准:评估一个自动地控制的切割系统(endocut 模式) 是否能与常规混合切割模式相比在 EST 以后减少内视镜的括约肌切开术(EST ) 和浆液血淀粉酶过多的复杂并发症率。方法:从 2001 年 1 月到 2003 年 10 月,有胆总管石病的 134 个病人在括约肌切开术的时候被分到任何一个 endocut 模式组或常规混合切割模式组。二个组回顾地在 EST 和浆液淀粉酶以后为复杂并发症被比较水平在前和在过程以后的 24 h。结果:对待的 134 个病人, 79 被分到常规混合切割模式组, 55 组织到 endocut 模式。在年龄,性别,和在在二个组之间的 EST 前的浆液淀粉酶水平没有有效差量。复杂并发症在 endocut 模式组(9%) 的 5 个病人被发现:血淀粉酶过多(比正常高 5 倍) 在 4 并且在 1 的中等胰腺炎。复杂并发症在常规混合切割模式组(16%) 的 13 个病人被发现:在 12 的血淀粉酶过多和在 1 的中等胰腺炎。浆液淀粉酶层次在两个组被提高在 EST (P<0.02 ) 以后的 24 h。在在常规混合切割模式的 EST 以后的 24 h 组织的平均浆液淀粉酶水平在 endocut 模式组(P<0.05 ) 比那显著地高。结论:Endocut 模式由减少血淀粉酶过多在 EST 以后为胰腺炎在常规混合切割模式上提供一个安全优点。 | Hirotada Akiho Yorinobu Sumida Kazuya Akahoshi Atsuhiko Murata Jiro Ouchi Yasuaki Motomura Taisuke Toyomasu Mitsuhide Kimura Masaru Kubokawa Masahiro Matsumoto Shingo Endo Kazuhiko Nakamura | 2006 | World Journal of Gastroenterology2006，12，13： | 6 |
| 3 | 64-slice multidetector computed tomography evaluation of gastrointestinal tract perforation site: detectability of direct findings in upper and lower GI tract显示文摘 | Sota Oguro Tomohiro Funabiki Koji Hosoda Yukio Inoue Takashi Yamane Michihiro Sato Mitsuhide Kitano Masahiro Jinzaki | 2010 | European Radiology2010，，6： | 3 |
| 4 | Basic helix-loop-helix transcription factors DEC1 and DEC2 regulatethe paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer cells显示文摘 | Yunyan Wu Fuyuki Sato Ujjal Bhawal Takeshi Kawamoto Katsumi Fujimoto Mitsuhide Noshiro Satoko Morohashi Yukio Kato Hiroshi Kijima | 2011 | International Journal of Molecular Medicine2011，，4： | 3 |
| 5 | Hepatic artery pseudoaneurysm associated with cholecystitis that ruptured into the gallbladder显示文摘 | Tomotaka Akatsu Shinobu Hayashi Tomohisa Egawa Masakazu Doi Atsushi Nagashima Mitsuhide Kitano Takashi Yamane Hiroshi Yoshii Masaki Kitajima | 2004 | Journal of Gastroenterology2004，，9： | 2 |
| 6 | Novel hexagonal structure and ultrahigh strength of magnesium solid solution in the Mg–Zn–Y system显示文摘 | Akihisa Inoue Yoshihito Kawamura Mitsuhide Matsushita Kentaro Hayashi Junichi Koike | 2001 | Journal of Materials Research2001，，7： | 2 |
| 7 | Combina- tion Chemotherapy with Cyelophosphamide, Vincristine, and Da- earbazine in Patients with Malignant Pheoehromocytoma and Para- ganglioma显示文摘 | Akiyo Tanabe Mitsuhide Naruse Kaoru Nomura | 2013 | Horm Cane2013，4，： | 1 |
| 8 | Computed tomngraphic scanning and selective laparoscopy in the diagnosis of blunt bowel injury:a prospective study显示文摘 | Mitsuhide K Junichi S Atsushi N | 2005 | J Trauma2005，58，4： | 1 |
| 9 | Lep?tin-to adiponectin ratio as a potential atherogenic index in obese type 2 diabetic patients显示文摘 | Noriko Satoh Mitsuhide Naruse Takeshi Usui | 2004 | Diabetes Care2004，27，0： | 1 |
| 10 | Prospective Comparative Study on the Acceptability of Unsedated Transnasal Endoscopy in Younger Versus Older Patients显示文摘 | Atsuhiko Murata Kazuya Akahoshi Yasuaki Motomura Noriaki Matsui Masaru Kubokawa Mitsuhide Kimura Jiro Ouchi Kuniomi Honda Shingo Endo Kazuhiko Nakamura Ryoichi Takayanagi | 2008 | Journal of Clinical Gastroenterology2008，，9： | 1 |
| 11 | Direct observation of icosahedral cluster in Zr70Pd30 binary glassy alloy显示文摘 | Junji Saida Mitsuhide Matsushita Akihisa Inoue | | 0，，3： | 1 |
| 12 | Plasma concentration of immunoreactive vascular endothelial growth factor and its relation to smoking显示文摘 | Taro Wasada Reiko Kawahara Kozo Katsumori Mitsuhide Naruse Yasue Omori | 1998 | Metabolism1998，，： | 1 |
| 13 | Regulation of nuclear retention of glucocorticoid receptor by nuclear Hsp90 显示文摘 | Katsuya Tago Fujiko Tsukahara Mitsuhide Naruse | 2004 | Mol Cell Endocrinol2004，213，： | 1 |
| 14 | Novel hexagonal structure and ultrahigh strength of magnesium solid solution in the Mg-Zn-Y system显示文摘 | Yoshihito K Mitsuhide M | 2001 | J Mater Res2001，16，7： | 1 |
| 15 | High strength nanocrystalline Mg-based alloys显示文摘 | Yoshihito K Mitsuhide M | 2002 | Mater Sci Forum2002，，： | 1 |
| 16 | nanomcter-sized phase-change recording using a scanning near-field optical microscope with a laser diode显示文摘 | Sumio Hosaka Toshimichi Shintanz Mitsuhide | 1996 | Applied Physics1996，35，2： | 1 |
| 17 | Effectiveness of aldosterone blockade in patients with diabetic nephropathy显示文摘 | Atsuhisa S Koichi H Mitsuhide N | 2003 | Hypertension2003，41，2： | 1 |
| 18 | The Adrenal Vein Sampling International Study (AVIS) for Identifying the Major Subtypes of Primary Aldosteronism显示文摘 | Gian Paolo Rossi Marlena Barisa Bruno Allolio Richard J. Auchus Laurence Amar Debbie Cohen Christoph Degenhart Jaap Deinum Evelyn Fischer Richard Gordon Ralph Kickuth Gregory Kline Andre Lacroix Steven Magill Diego Miotto Mitsuhide Naruse Tetsuo Nishikawa | 2012 | The Journal of Clinical Endocrinology & Metabolism2012，，5： | 1 |
| 19 | Hsp90 inhibitors attenuate effect of dexamethasone on activated NF-κ B and AP-1显示文摘 | Katsuya T Fujiko T Mitsuhide N | 2004 | Life Sci2004，74，2： | 1 |
| 20 | 醛固酮与原发性醛固酮增多症的研究进展显示文摘近来的研究突出了醛固酮的两个新的方面。一个是醛固酮对心血管系统的直接病理作用,醛固酮通过激活氧自由基的机制引起血管内皮功能紊乱和血管平滑肌细胞凋亡。虽然阻断肾素一血管紧张素系统是心血管疾病的上要治疗手段,但是一个重要的现象是在长期使用血管紧张素转换酶抑制剂(ACEI)和血管紧张素受体拮抗剂(ARB)的过程中观察到醛周酮水平的再升高(醛崮酮突破,aldosterone breakthrough)。 | Mitsuhide Naruse | 2006 | 中华医学信息导报2006，21，17： | 0 |
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