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| 1 | Effects of Helicobacterpyloriinfection on gastric emptying rate in patients with non-ulcer dyspepsia显示文摘AIM: The pathogenesis of delayed gastric emptying in patients with non-ulcer dyspepsia (NUD) remains unclear. We aimed to examine whether gastric emptying rate in NUD patients was associated with Helicobacterpylori(Hpylori) infection and whether it was affected by eradication of the infection. METHODS: Gastric emptying rate of a mixed solid-liquid meal was assessed by the paracetamol absorption method in NUD patients and asymptomatic controls (n=-17). Hpylori status was assessed by serology and biopsy urease test. Hpylori-positive NUD patients (n=-23) received 10-day triple eradication therapy. H pylori status was re-assessed by biopsy urease test four weeks later, and if eradication was confirmed, gastric emptying rate was re-evaluated. RESULTS: Thirty-three NUD patients and 17 controls were evaluated. NUD patients had significantly delayed gastric emptying compared with controls. The mean maximum plasma paracetamol concentration divided by body mass (Cmax/BM) was 0.173 and 0.224 mg/L.kg respectively (P=0.02), the mean area under plasma paracetamol concentration-time curve divided by body mass (AUC/BM) was 18.42 and 24.39 mg.min/L.kg respectively (P=-0.01). Gastric emptying rate did not differ significantly between H pylori-positive and H pylori-negative NUD patients. The mean Cmax/BM was 0.172 and 0.177 mg/Ukg respectively (P=-0.58), the mean AUC/BM was 18.43 and 18.38 rag.min/L.kg respectively (P=0.91). Among 14 NUD patients who were initially H pylori-positive, confirmed eradication of the infection did not significantly alter gastric emptying rate. The mean Cmax/BM was 0.171 and 0.160 mg/Ukg before and after Hp eradication, respectively (P=0.64), the mean AUC/BM was 17.41 and 18.02 mg.min/Ukg before and after eradication, respectively (P=-0.93). CONCLUSION: Although gastric emptying is delayed in NUD patients compared with controls, gastric emptying rate is not associated with H pylori status nor it is affected by eradication of the infection. | Grigoris I Leontiadis George I Minopoulos Efstratios Maltezos Stamatia Kotsiou Konstantinos I Manolas Konstantinos Simopoulos Dimitrios Hatseras | 2004 | World Journal of Gastroenterology2004，10，12： | 9 |
| 2 | Mucocele of the appendix: a report of five cases显示文摘 | M. Pitiakoudis A. K. Tsaroucha K. Mimidis A. Polychronidis G. Minopoulos C. Simopoulos | 2004 | Techniques in Coloproctology2004，，2： | 1 |
| 3 | Perceptions of Hazard and Risk on Santorini 显示文摘 | Dominey-Howes D Minos- Minopoulos D | 2004 | Journal of Volcanology and Geothermal Research2004，，137： | 1 |
| 4 | Amifostine before Chemotherapy:Improved Tolerance Profile of the Subcutaneous over the Intravenous Route显示文摘 | Koukourakis M I Simopoulos C Minopoulos G | 2003 | Clin Cancer Res2003，9，9： | 1 |
| 5 | Both early-onset and late-onset ventilator-associated pneumonia are caused mainly by potentially multiresistant bacteria显示文摘 | Elpis Giantsou Nikolaos Liratzopoulos Eleni Efraimidou Maria Panopoulou Eleonora Alepopoulou Sofia Kartali-Ktenidou George I. Minopoulos Spyros Zakynthinos Konstantinos I. Manolas | 2005 | Intensive Care Medicine2005，，11： | 1 |
| 6 | Angiogenesis relates to estrogen receptor negativity, c-erbB-2 overexpression and early relapse in node-negative ductal carcinoma of the breast显示文摘 | Manolas C Minopoulos G | 2003 | Int J Surg Pathol2003，11，1： | 1 |
| 7 | Emergency operations for carcinoma of the colon显示文摘 | Minopoulos GI Lyratzopoulas N Efremidou HI | 2004 | Tech Coloproctol2004，8，1： | 1 |
| 8 | Angiogenesis relates to estrogen receptor negativity,c-erbB-2 overexpression and early relapse in node-negative ductal carcinoma of the breast显示文摘 | Koukourakis M I Manolas C Minopoulos G | 2003 | Int J Surg Pathol2003，11，1： | 1 |
| 9 | Angiogenesis relates to estrogen receptor negativity,c-erbB-2 overexpression and early relapse in node-negative ductal carcinoma of the breast显示文摘 | Koukourakis MI Manolas C Minopoulos G | | 0，，01： | 1 |
| 10 | Angiogenesis relates to estrogen receptor negativity,c-erbB-2 over-expression and early relapse in node-negative ductal carcinoma of the breast 显示文摘 | Koukourakis MI Manolas C Minopoulos G | 2003 | Int J Surg pathol2003，11，1： | 1 |
| 11 | Therapie des rezidivierenden epithelialen Ovarialkarzinoms mit sekund?rer Tumorreduktion und kontinuierlicher intraoperativer intraperitonealer hyperthermischer Chemoperfusion (CIIPHCP)显示文摘 | K. Chatzigeorgiou S. Economou G. Chrysafis A. Dimasis G. Zafiriou K. Setzis N. Lyratzopoulos G. Minopoulos K. Manolas N. Chatzigeorgiou | 2003 | Zentralbl Gynakol2003，，10： | 1 |
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