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| 1 | Incidence trends and survival prediction of hepatoblastoma in children:a population-based study显示文摘Background:Hepatoblastoma is a rare disease that nevertheless accounts for the majority of liver malignancies in children.Due to limited epidemiological data,therapy for hepatoblastoma tends to be individualized.This study aimed to evaluate incidence trends of hepatoblastoma and to develop a nomogram to predict the survival of children with newly diagnosed hepatoblastoma on a population-based level.Methods:Individuals up to 18 years of age with hepatoblastoma recorded in 18 registries of the Surveillance,Epi-demiology,and End Results(SEER)database between 2004 and 2015 were examined.Joinpoint regression analyses were applied to assess incidence trends in annual percentage change(APC).Multivariable Cox regression was used to identify factors associated with overall survival(OS).A nomogram was constructed to predict OS in individual cases based on independent predictors.Concordance index(C-index)and calibration curves were used to evaluate predic-tive performance.Results:Between 2004 and 2015,hepatoblastoma incidence increased significantly(APC,2.2%;95%confidence interval[CI]0.5%to 3.8%,P<0.05).In particular,this increase was observed among 2-to 4-year-old patients,males,and African-Americans.The 5-and 10-year OS rates were 81.5%and 81.0%,respectively.Age of 2 to 4 years,Afri-can-American ethnicity,and no surgery were independent predictors for short OS.Distant disease at presentation was found not to be an independent factor of survival.The nomogram had a C-index of 0.79(95%CI 0.74-0.84)with appropriate calibration curve fitting.Conclusions:We constructed a nomogram that integrates common factors associated with survival for hepatoblas-toma patients.It provides accurate prognostic prediction for children with hepatoblastoma. | Jincheng Feng Georgios Polychronidis Ulrike Heger Giovanni Frongia Arianeb Mehrabi Katrin Hoffmann | 2019 | Cancer Communications2019，39，1： | 10 |
| 2 | Circulating vegf levels in the serum of gastric cancer patients:Correlation with pathological variables,patient survival,and tumor surgery显示文摘 | Karayiannakis AJ Syrigos KN Polychronidis A | 2002 | Ann Surg2002，236，： | 1 |
| 3 | Circulating VEGF levels in the serum of gastric cancer patients:correlation with pathological variables, patient survival,and tumor surgery 显示文摘 | KARAYIANNAKIS AJ SYRIGOS KN POLYCHRONIDIS A | 2002 | Ann Surg2002，236，1： | 1 |
| 4 | Circu- lating VEGF levels in the serum of gastric cancer patients 显示文摘 | Karayiannakis A Syrigos KN Polychronidis A | 2002 | Ann Surg2002，236，： | 1 |
| 5 | Circulating VEGF levels in the serum of gastric cancer patients: correlation with pathological variables, patient survival, and tumor surgery显示文摘 | Karayiannakis A J Syrigos KN Polychronidis A | 2002 | Ann Surg2002，236，1： | 1 |
| 6 | Circulating VEGF levels in the serum of gastric cancer patients:correlation with pathological variables,patient survival and tmorsurgery显示文摘 | Karayiannakis AJ Syrigos KN Polychronidis A | 2002 | Ann Surg2002，236，： | 1 |
| 7 | Laparoscopic cholecystectomy in patients with previous upper or lower ab- dominal surgery 显示文摘 | Karayiannakis A J Polychronidis A Perente S | 2004 | Surg Endosc2004，18，1： | 1 |
| 8 | Laparoscopic cholecystectomy in patients with previous upper or lower abdominal surgery显示文摘 | Karayiannakis A J Polychronidis A Perente S | 2004 | Surg Endosc2004，18，1： | 1 |
| 9 | Risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy显示文摘 | SIMOPOULOS C BOTAITIS S POLYCHRONIDIS A | 2005 | Surg Endosc2005，19，7： | 1 |
| 10 | Serum levels of tumor necrosis factor-alpha and nutritional status in pancreatic cancer patients显示文摘 | Karayiannakis A J Syrigos K N Polychronidis A | 2001 | Anticancer Res2001，21，2： | 1 |
| 11 | Risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy显示文摘 | C. Simopoulos S. Botaitis A. Polychronidis G. Tripsianis A. J Karayiannakis | 2005 | Surgical Endoscopy2005，，7： | 1 |
| 12 | Surgical treatment of femoral artery ilrfected false aneurysms in drug abusers显示文摘 | Lazarides MK Georgiadis GS Polychronidis A | 2005 | ANZ J Surg2005，75，11： | 1 |
| 13 | Mucocele of the appendix: a report of five cases显示文摘 | M. Pitiakoudis A. K. Tsaroucha K. Mimidis A. Polychronidis G. Minopoulos C. Simopoulos | 2004 | Techniques in Coloproctology2004，，2： | 1 |
| 14 | Laparoscopie cholecystectomy in patients with previous upper or lower abdominal surgery显示文摘 | Karayiannakis A J Polychronidis A Perente S | 2004 | SurgEndosc2004，18，1： | 1 |
| 15 | Risk factors for conversion of laparoscopic cholecystectomy to open cholecystecoty 显示文摘 | Simopoulos C Botaitis S Polychronidis A | 2005 | Surg Endosc2005，19，7： | 1 |
| 16 | Twenty years of laparoscopic cholecystectomy:Philippe Mouret--March 17,1987显示文摘 | Polychronidis A Laftsidis P Bounovas A | 2008 | JSLS2008，，： | 1 |
| 17 | Laparoscopic cholecystectomy in patients with previous upper or lower abdominal surgery显示文摘 | Karayiannakis AJ Polychronidis A Perente S | 2004 | Surg Endosc2004，18，1： | 1 |
| 18 | Twenty years of laparoscopic cholecystectomy: Philippe Mouret--March 17, 1987 显示文摘 | Polychronidis A Laftsidis P Bounovas A | 2008 | JSLS2008，12，1： | 1 |
| 19 | In traperitoneal air in the diagnosis of blunt diaphragmatic rupture 显示文摘 | Polychronidis A Bounovas A Didilis B | 2001 | J Cardiovasc Surg2001，42，6： | 1 |
| 20 | Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer显示文摘 | Koukourakis MI Giatromanolaki A Polychronidis A | 2006 | Cancer Sci2006，97，7： | 1 |
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